Tumor microvascular architecture phenotype (T-MAP) as a new concept for studies of angiogenesis and oncology

Journal of Neuro-Oncology

Volumn 80, Issue 2, 2006, Pages 211-213

  Bian, Xiu Wu ^a   Wang, Qing Liang ^a   Xiao, Hua Liang ^a   Wang, Ji Ming ^b  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Angiogenesis; Glioma; Heterogeneity; Tumor microvascular architecture phenotype (T MAP)

Indexed keywords

ANGIOGENESIS INHIBITOR; CELL MARKER; EPHRIN B2; EPHRIN RECEPTOR B4;

ANGIOGENESIS; ARTICLE; BRAIN BLOOD FLOW; CANCER DIAGNOSIS; CANCER INVASION; CARCINOGENESIS; CELL DENSITY; CELL HETEROGENEITY; CELL STRUCTURE; DRUG DESIGN; ENDOTHELIUM CELL; GENE EXPRESSION PROFILING; GENETIC VARIABILITY; GLIOMA; HUMAN; ONCOLOGY; PHENOTYPE; PREDICTION; TREATMENT OUTCOME;

BRAIN NEOPLASMS; CAPILLARIES; GLIOMA; HUMANS; IMMUNOHISTOCHEMISTRY; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; PHENOTYPE; REGIONAL BLOOD FLOW;

EID: 33750346288     PISSN: 0167594X     EISSN: 15737373     Source Type: Journal    
DOI: 10.1007/s11060-006-9167-4     Document Type: Article

References (7)

1. Ribatti D, Nico B, Vacca A, Roncali L, Dammacco F (2002) Endothelial cell heterogeneity and organ specificity. J Hematother Stem Cell Res 11:81-90
2. Lacorre DA, Baekkevold ES, Garrido I, Brandtzaeg P, Haraldsen G, Amalric F, Girard JP (2004). Plasticity of endothelial cells: Rapid dedifferentiation of freshly isolated high endothelial venule endothelial cells outside the lymphoid tissue microenvironment. Blood 103:4164-4172
3. Bian XW, Chen JH, Jiang XF, Bai JS, Zhang X (2004) Angiogenesis as an immunopharmacologic target in inflammation and cancer. Int Immunopharmacol 4:1537-1547
4. Bian XW, Jiang XF, Chen JH, Bai JS, Dai C, Wang QL, Lu JY, Zhao W, Xin R, Liu MY, Shi JQ, Wang JM (2006) Increased angiogenic capabilities of endothelial cells from microvessels of malignant human gliomas. Int Immunopharmacol 5:90-99
5. Miebach S, Grau S, Humme V, Rieckmann P, Tonn J-C, Goldbrunner RH (2006) Isolation and culture of microvascular endothelial cells from gliomas of different WHO grades. J Neuro-Oncol 76:39-48
6. Shaked Y, Bertolini F, Man S, et al (2005) Genetic heterogeneity of the vasculogenic phenotype parallels angiogenesis; implications for cellular surrogate marker analysis of antiangiogenesis. Cancer Cell 7(1):101-111
7. Bian XW, Du LL, Shi JQ, Cheng YS, Liu FX (2000) Correlation of bFGF, FGFR-1 and VEGF expression with vascularity and malignancy of human astrocytomas. Anal Quant Cytol Histol 22:267-274