Infertility, ovulation induction treatments and the incidence of breast cancer - A historical prospective cohort of Israeli women

Breast Cancer Research and Treatment

Volumn 100, Issue 2, 2006, Pages 201-212

  Lerner Geva, L ^a,i   Keinan Boker, L ^b,i   Blumstein, T ^a   Boyko, V ^a   Olmar, L ^a   Mashiach, S ^c,i   Rabinovici, J ^c,i   Potashnik, G ^d   Lunenfeld, E ^d   Schenker, J G ^e   Shushan, A ^e   Fishman, A ^f,i   Cohen, I ^f,i   Vagman, I ^g   Lunenfeld, B ^h  

^a GERTNER INSTITUTE FOR EPIDEMIOLOGY AND HEALTH POLICY RESEARCH   (Israel)

^b UNIVERSITY OF HAIFA   (Israel)

^c SHEBA MEDICAL CENTER   (Israel)

^d BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^e HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^f MEIR MEDICAL CENTER   (Israel)

^g TEL AVIV SOURASKY MEDICAL CENTER   (Israel)

^h BAR ILAN UNIVERSITY   (Israel)

ⁱ TEL AVIV UNIVERSITY   (Israel)

Author keywords

Breast cancer; Clomiphene citrate; Infertility; Ovulation induction; Prospective

Indexed keywords

CLOMIFENE CITRATE;

ADULT; ARTICLE; BREAST CANCER; CANCER RISK; CONTROLLED STUDY; FEMALE; FOLLOW UP; HUMAN; INCIDENCE; INFERTILITY; INTERVIEW; MAJOR CLINICAL STUDY; MEDICAL RECORD; OVULATION; OVULATION INDUCTION; PRIORITY JOURNAL;

ADULT; BREAST NEOPLASMS; CASE-CONTROL STUDIES; CLOMIPHENE; COHORT STUDIES; FEMALE; FERTILITY AGENTS, FEMALE; HUMANS; INCIDENCE; INFERTILITY, FEMALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; OVULATION INDUCTION; PROSPECTIVE STUDIES;

EID: 33750340235     PISSN: 01676806     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10549-006-9238-4     Document Type: Article

References (56)

1. Mosher WD, Pratt WF (1991) Fecundity and infertility in the United States: incidence and trends. Fertil Steril 56:192-198
2. Schenker JG, Laufer N, Weinstein D, Yarkoni S (1980) Quintuplet pregnancies. Eur J Obstet Gynecol Reprod Biol 10:257-268
3. Hack M, Brish M, Serr DM, Insler V, Salomy M, Lunenfeld B (1972) Outcome of pregnancy after induced ovulation. Follow-up of pregnancies and children born after clomiphene therapy. JAMA 220:1329-1333
4. Oelsner G, Menashe Y, Tur-Kaspa I, Ben-Rafael Z, Blankstein J, Serr DM, Mashiach S (1989) The role of gonadotropins in the etiology of ectopic pregnancy. Fertil Steril 52:514-516
5. Bider D, Menashe Y, Oelsner G, Serr DM, Mashiach S, Ben-Rafael Z (1989) Ovarian hyperstimulation syndrome due to exogenous gonadotropin administration. Acta Obstet Gynecol Scand 68:511-514
6. Schenker JG, Weinstein D (1978) Ovarian hyperstimulation syndrome: a current survey. Fertil Steril 30:255-268
7. Navot D, Relou A, Birkenfeld A, Rabinowitz R, Brzezinski A, Margalioth EJ (1988) Risk factors and prognostic variables in the ovarian hyperstimulation syndrome. Am J Obstet Gynceol 159:210-215
8. Johannes CB, Caro JJ, Hartz SC, Marrs R (1993) Adverse effects of ovulatory stimulants: a review. Assis Reprod Rev 3:68-74
9. Schenker JG, Ezra Y (1994) Complications of assisted reproductive techniques. Fertil Steril 61:411-422
10. Cancer in Israel, State of Israel Ministry of Health, Israel Cancer Registry, 1996
11. Kelsey JL, Gammon MD (1991) The epidemiology of breast cancer. Cancer 41:146-165
12. Key TJ, Verkasaklo PK, Banke E (2001) Epidemiology of breast cancer. Lancet Oncol 2:133-140
13. Sutherland RL, Watts CKW, Hall RE, Ruenitz PC (1987) Mechanisms of growth inhibition by non-steroidal antiestrogens in human breast cancer cells. J Steroid Biochem 27:891-897
14. Gammon M, Thompson WD (1990) Infertility and breast cancer: a population-based case-control study. Am J Epidemiol 132:708-716
15. Braga C, Negri E, La Vecchia C, Parazzini F, Dal Maso L, Franceschi S (1996) Fertility treatment and risk of breast cancer. Hum Reprod 11:300-303
16. Ricci E, Parazzini F, Negri E, Marsico S, La Vecchia C (1999) Fertility and the risk of breast cancer. Human Reprod 14:1653-1655
17. Burkman RT, Tang MC, Malone KE, Marchbanks PA, McDonald JA, Folger SG (2003) Infertility and the risk of breast cancer: findings from the national institute of child health and human development women's contraceptive and reproductive experiences study. Fertil Steril 79:844-854
18. Cowan LD, Gordis L, Tonascia JA, Jones GS (1981) Breast cancer incidence in women with a history of progesterone deficiency. Am J Epidemiol 114:209-217
19. Coulam CB, Annegers JF, Kranz JS (1983) Chronic anovulation syndrome and associated neoplasia. Obstet Gynecol 61:403-407
20. Ron E, Lunenfeld B, Menczer J, Blumstein T, Katz L, Oelsner G, Serr D (1987) Cancer incidence in a cohort of infertile women. Am J Epidemiol 125:780-790
21. Brinton LA, Melton LJ, Malkasian GD Jr, Bond A, Hoover R (1989) Cancer risk after evaluation for infertility. Am J Epidemiol 129:712-722
22. Modan B, Ron E, Lerner-Geva L, Blumstein T, Menczer J, Rabinovici J, Oelsner G, Freedman L, Mashiach S, Lunenfeld B (1998) Cancer incidence in a cohort of infertile women. Am J Epidemiol 147:1038-1042
23. Rossing MA, Daling JR, Weiss NS, Moore DE, Self SGL (1996) Risk of breast cancer in a cohort of infertile women. Gynecol Oncol 60:3-7
24. Potashnik G, Lerner-Geva L, Genkin L, Chetrit A, Lunenfeld E, Porath A (1999) Fertility drugs and the risk of breast and ovarian cancers: results of a long-term follow-up study. Fertil Steril 71:853-859
25. Doyle P, Maconochie N, Beral V, Swerdlow AJ, Tan SL (2002) Cancer incidence following treatment for infertility at a clinic in the UK. Human Reprod 17:2209-2213
26. Brzezinski A, Peretz T, Mor-Yosef S, Schenker JG (1994) Ovarian stimulation and breast cancer: is there a link? Gynecol Oncol 52:292-295
27. Venn A, Watson L, Lumley J, Giles G, King C, Healy D (1995) Breast and ovarian cancer incidence after infertility and in-vitro fertilization. Lancet 346:995-1000
28. Venn A, Watson L, Bruinsma F, Giles G, Healy D (1999) Risk of cancer after use of fertility drugs with in-vitro fertilization. Lancet 354:1586-1590
29. Dor J, Lerner-Geva L, Rabinovici J, Chetrit A, Levran D, Lunenfeld B, Mashiach S, Modan B (2002) Cancer incidence in a cohort of infertile women treated with in vitro fertilization. Fertil Steril 77:324-327
30. Lerner-Geva L, Geva E, Lessing JB, Chetrit A, Modan B, Amit A (2003) The possible association between in vitro fertilization treatments and cancer development. Int J Gynecol Cancer 13:23-27
31. Gauthier E, Paoletti X, Clavel-Chapelon F, the E3N Group (2004) Breast cancer risk associated with being treated for infertility: results from the French E3N cohort study. Human Reprod 19:2216-2221
32. Brinton LA, Scoccia B, Moghissi KS, Westhoff CL, Althuis MD, Mabie JE, Lamb EJ (2004) Breast cancer risk associated with ovulation-stimulating drug. Hum Reprod 19(9):2005-2013
33. Fishler Y, Chetrit A, Barchana M, Modan B (2003) The completeness of the national cancer registry database. Methods and results. Completeness of the data in the year 1991 and its implications on the completeness of current data. Israel Center for Disease Control, Israel, publication # 230 [Hebrew]
34. Rothman KJ, Boice JD Jr (1979) Epidemiologic analysis with a programmable calculator. US GPO, Washington, DC (DHEW publication no. (NIH) 79-1649)
35. SAS/STAT Software (1996) Changes and enhancements through release 6.11. SAS Institute Inc., Cary, NC, USA
36. Garland M, Hunter DJ, Colditz GA, Manson JE, Stampfer MJ, Spiegelman D, Speizer F, Willett WC (1998) Menstrual cycle characteristics and history of ovulatory infertility in relation to breast cancer risk in a large cohort of US women. Am J Epidemiol 147:636-643
37. Kelsey JL, Bernstein L (1996) Epidemiology and prevention of breast cancer. Ann Rev Public Health 17:47-67
38. Tung KH, Wilkens LR, Wu AH, Mcduffie K, Nomura AMY, Koionel LN, Terada KY, Goodman MT (2005) Effect of anovulation factors on pre and postmenopausal ovarian cancer risk: revisiting the incessant ovulation hypothesis. Am J Epidemiol 161:321-329
39. Key TJ, Pike MC (1998) The role of oestrogens and progestagens in the epidemiology and prevention of breast cancer. Eur J Cancer Clin Oncol 24:29-43
40. Klip H, Burger CW, Kenemans P, van Leeuwen FE (2000) Cancer risk associated with subfertility and ovulation induction: a review. Cancer Causes and Control 11:319-344
41. Chavez-MacGregor M, Elias SG, Onland-Moret NC, van der Schouw YT, Van Gils CH, Monninkhof E, Grobbee DE, Peeters PH (2005) Postmenopausal breast cancer risk and cumulative number of menstrual cycles. Cancer Epidemiol Biomarkers Prev 14(4):799-804
42. Speroff L, Glass RH, Kase NG (1999) Induction of ovulation. In: Clinical, gynecologic, endocrinology and infertility. Lippincott Williams and Wilkins, Baltimore, Maryland, USA, pp 1097-1132
43. Clark JH, Markaverich BM (1982) The agonist-antagonist properties of clomiphene: a review. Pharmacol Ther 15:467-519
44. Adashi EY (1984) Clomiphene citrate: mechanism(s) and site(s) of action - a hypothesis revisited. Fertil Steril 42:331-344
45. Henderson BE, Ross RK, Judd HL, Krailo MD, Pike MC (1985) Do regular ovulatory cycles increase breast cancer risk? Cancer 56:1206-1208
46. Milliken EL, Ameduri RK, Landis MD, Behrooz A, Abdul-Karim FW, Keri RA (2002) Ovarian hyperstimulation by LH leads to mammary gland hyperplasia and cancer predisposition in transgenic mice. Endocrinol 143:3671-3680
47. Adlercreutz H (1998) Epidemiology of phytoestrogens. Baillieres Clin Endocrinol Metab 12:605-623
48. Messina MJ, Loprinzi CL (2001) Soy for breast cancer survivals: a critical review of the literature. J Nutr 131:3095S-3108S
49. Petrakis NL, Barnes S, King EB, Lowenstein J, Wiencke J, Lee MM, Miike R, Kirk M, Coward L (1996) Stimulatory influence of soy protein isolate on breast secretion in pre- and postmenopausal women. Cancer Epidemiol Biomarkers Prev 5:785-794
50. Peeters PHM, Keinan-Boker L, van der Schouw YT, Grobbee DE (2003) Phytoestrogens and breast cancer risk. Review of the epidemiological evidence. Breast Cancer Res Treat 77:171-183
51. This P, De La Rochefordiere A, Clough K, Fourquet A, Magdelenat H, the Breast Cancer Group of the Institute Curie (2001) Phytoestrogens after breast cancer. Endocrin Related Cancer 8:129-134
52. Baker VL, Jaffe RB (1996) Clinical uses of antiestrogens. Obstet Gynecol Surv 51(1):45-59
53. Lerner LJ, Jordan VC (1990) Development of antiestrogens and their use in breast cancer: eighth chain memorial lecture Cancer Res 50:4177-4189
54. Palmer JR, Hatch EE, Rosenberg CL, Hartge P, Kaufman RH, Titus-Ernstoff L, Noller KL, Herbst AL, Rao RS, Troisi R, Colton T, Hoover RN (2002) Risk of breast cancer in women exposed to diethylstilbestrol in utero: preliminary results (United States). Cancer Causes and Control 13:753-758
55. Goldstein S, Siddhantu S, Ciaccia AV, Plouffe L Jr (2000) A pharmacological review of selective oestrogen receptor modulators. Hum Reprod Update 6(3):212-224
56. Baumann RJ, Bush TL, Cross-Doersen DE, Cashman EA, Wright PS, Zwolshen JH, Davis GF, Matthews DP, Bender DM, Bitonti AJ (1998) Clomiphene analogs with activity in vitro and in vivo against human breast cancer cells. Biochemical Pharmacol 55(6):841-851