Leishmania major: Reactive oxygen species and interferon gamma induction by soluble lipophosphoglycan of stationary phase promastigotes

Experimental Parasitology

Volumn 114, Issue 4, 2006, Pages 323-328

  Kavoosi, Gholamreza ^a   Ardestani, Sussan K ^a   Kariminia, Amina ^b   Abolhassani, Mohssen ^b   Turco, Salvatore J ^c  

^a UNIVERSITY OF TEHRAN   (Iran)

^b PASTEUR INSTITUTE OF IRAN   (Iran)

^c UNIVERSITY OF KENTUCKY MEDICAL CENTER   (United States)

Author keywords

IFN ; IL 10; IL 12; Leishmania major; Membrane LPG; ROS; Soluble LPG

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; LIPOPHOSPHOGLYCAN; PROTOZOAL VACCINE; REACTIVE OXYGEN METABOLITE;

ARTICLE; CELL CULTURE; CELL ISOLATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DRUG PURITY; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOLOGICAL PARAMETERS; LEISHMANIA MAJOR; MEMBRANE; NONHUMAN; NORMAL HUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROMASTIGOTE; PROTEIN INDUCTION; SUPERNATANT; TH1 CELL; THIN LAYER CHROMATOGRAPHY;

ANIMALS; BLOTTING, WESTERN; CELL MEMBRANE; CHROMATOGRAPHY, THIN LAYER; GLYCOSPHINGOLIPIDS; HUMANS; INTERFERON TYPE II; INTERLEUKIN-10; INTERLEUKIN-12; LEISHMANIA MAJOR; LEISHMANIASIS, CUTANEOUS; LEUKOCYTES, MONONUCLEAR; MICE; MICE, INBRED BALB C; PROTOZOAN VACCINES; REACTIVE OXYGEN SPECIES; SOLUBILITY;

LEISHMANIA MAJOR; PROTOZOA;

EID: 33750339808     PISSN: 00144894     EISSN: 10902449     Source Type: Journal    
DOI: 10.1016/j.exppara.2006.04.006     Document Type: Article

References (24)

1. Aebischer T., Bennett C.L., Pelizzola M., Vizzardelli C., Pavelka N., Urbano M., Capozzoli M., Luchini A., Ilg T., Granucci F., Blackburn C.C., and Ricciardi-Castagnoli P. A critical role for lipophosphoglycan in proinflammatory responses of dendritic cells to Leishmania mexicana. European Journal of Immunology 35 (2005) 476-486
2. Ames B.N. Assay of inorganic phosphate, total phosphate and phosphatases. Methods in Enzymology 8 (1996) 115-118
3. Balaraman S., Singh V.K., Tewary P., and Madhubala R. Leishmania lipophosphoglycan activates the transcription factor activating protein 1 in J774A.1 macrophages through the extracellular signal-related kinase (ERK) and p38 mitogen-activated protein kinase. Molecular and Biochemical Parasitology 139 (2005) 117-127
4. Becker I., Salaiza N., Aguirre M., Delagado J., Carrillo-carrasco N., Kobeh L.G., Ruiz A., Cervantes R., Torres A.P., Cabrera N., Gonzalez A., Maldonado C., and Isibasi A. Leishmania lipophosphoglycan activates NK cells through toll-like receptor-2. Molecular and Biochemical Parasitology 130 (2003) 65-74
5. Bhattacharya S., Ghosh S., Jhonson P.L., Battacharya S.K., and Majumdar S. Immunomodulatory role of IL-10 in visceral leishmaniasis: defective activation of protein kinase C mediated signal transduction. Infection and Immunity 69 (2001) 1499-1507
6. Conour J.E., Graham W.V., and Gaskins H.R. A combined in vitro/bioinformatic investigation of redox regulatory mechanisms governing cell cycle progression. Physiological Genomics 18 (2004) 196-205
7. Davies C.R., Cooper A.M., Peacock C., Lane R.P., and Blackwell J.M. Expression of LPG and GP63 by different developmental stages of Leishmania major in the sand fly Phlebotomus papatasi. Parasitology 101 (1990) 337-356
8. De Veer M.J., Curtis J.M., Baldwin T.M., Didonato J.A., Sexton A., Mc Conville M.J., Handman E., and Schofield L. MyD88 is essential for clearance of Leishmania major: possible role for lipophosphoglycan and toll-like receptor 2 signalling. European Journal of Immunology 33 (2003) 2822-2831
9. Descoteaux A., and Turco S.J. Glycoconjugate in Leishmania infectivity. Biochimica et Biophysica Acta 1455 (1999) 341-352
10. Handman E., and Bullen V.R.D. Interaction of Leishmania with host macrophage. Trends in Parasitology 18 (2002) 332-334
11. Ilg T., Stierhof Y.-D., Craik D., Simpson R., Handman E., and Bacic A. Purification and structural characterization of a filamentous, mucinlike proteophosphoglycan secreted by Leishmania parasites. Journal Biological Chemistry 271 (1996) 21583-21596
12. Ilg T., Stierhof Y.D., Wiese M., Mc Conville M.J., and Overath P. Characterization of phosphoglycan-containing secretory products of Leishmania. Parasitology 108 (1994) S63-S71
13. Liew F.Y., Wei X.-Q., and Proudfoot L. Cytokines and nitric oxide as effector molecules against parasitic infections. Philosophical transactions of the Royal Society of London. Series B 352 (1997) 1311-1316
14. Naderer T., Vince J.E., and Mc Conville M.J. Surface determinants of Leishmania parasites and their role in infectivity in the mammalian host. Current Molecular Medicine 4 (2004) 649-665
15. Nathan C. Specificity of a third kind: reactive oxygen and nitrogen intermediates in cell signaling. Journal of Clinical Investigation 111 (2003) 769-778
16. Rao P., and Pattabiraman T.N. Re-evolution of the phenol-sulfuric acid reaction for the estimation of hexoses and pentoses. Analytical Biochemistry 181 (1989) 18-22
17. + cells during initiation of infection. Journal of Experimental Medicine 179 (1994) 447-459
18. Ryan K.B., Smith Jr. M.F., Sanders M.K., and Ernst P.B. Reactive oxygen and nitrogen species differentially regulate toll-like receptor 4-mediated activation of NF-κB and interleukin-8 expression. Infection and Immunity 72 (2004) 2123-2130
19. Sacks D.L. Metacyclogenesis in Leishmania amastigotes. Experimental Parasitology 69 (1989) 100-103
20. Sacks D.L., Brodin T.N., and Turco S.J. Developmental modification of the lipophosphoglycan from Leishmania major promastogotes during metacyclogenesis. Molecular and Biochemical Parasitology 42 (1990) 225-234
21. Sacks D.L., Hieny S., and Sher A. Identification of cell surface carbohydrate and antigenic changes between noninfective and infective developmental stages of Leishmania major promastigotes. Journal of Immunology 135 (1985) 564-569
22. Tonui W.K., Mbati P.A., Anjili C.O., Orago A.S., Turco S.J., Githure J.I., and Koech D.K. Transmission blocking vaccine studies in leishmaniasis: I. Lipophosphoglycan is a promising transmission blocking vaccine molecule against cutaneous leishmaniasis. East African Medical Journal 78 (2001) 84-89
23. Turco S.J., Wilkerson M.A., and Clawsons D.R. Expression of an unusual acidic glycoconjugate in Leishmania donovanis. Journal of Biological Chemistry 259 (1984) 3883-3889
24. Werling D., Hope J.C., Howard C.J., and Jungi T.W. Differential production of cytokines, reactive oxygen and nitrogen by bovine macrophages and dendritic cells stimulated with toll-like receptor agonists. Immunology 111 (2004) 41-52