Production of polyclonal and monoclonal antibodies

Handbook of Laboratory Animal Science, Second Edition: Essential Principles and Practices

Volumn 1, Issue , 2002, Pages 391-411

  Hendriksen, Coenraad ^a   Hau, Jann ^b  

^a NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^b UPPSALA UNIVERSITY   (Sweden)

Author keywords

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Indexed keywords

EID: 33750338624     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (74)

1. Behring, E. von and Kitasato, Uber das Zustandekommen der Diphtherie-Immunität und der Tetanus-Immunität bei Tieren (Production of diphtheria immunity and tetanus immunity in animals), Deutsche Medizinische Wochenschrift, 49, 113, 1890.
2. Köhler, G. and Milstein, C., Continuous cultures of fused cells secreting antibody of predefined specificity, Nature, 256, 495, 1975.
3. Roitt, J., Brostoff, J., and Male, D., Immunology, 6th ed., Mosby, Baltimore, MD, 2001.
4. Austyn, J.M., and Wood, K.J., Principles of Cellular and Molecular Immunology. Oxford University Press, Oxford, 1994.
5. Smith, C.P., Jensen, D., Allen, T., and Kreger, M., Eds., Information resources for adjuvants and antibody production: comparisons and alternative technologies 1990-1997, AWIC Resources Series, 3, 1, 1997.
6. Leenaars, M., Claassen, E., and Boersma, W.J.A., Modulation of the humoral immune response; antigens and antigen presentation, in Immunology Methods Manual. I. Lefkovits, Ed., Academic Press, New York, 1996, p. 989.
7. Hanly, W.C., Artwohl, J.E., and Bennett, B.T., Review of polyclonal antibody production procedures in mammals and poultry, ILAR News, 37, 93, 1995.
8. McCullough, K.C., Hendriksen, C.F.M., and Seeback, T., In vitro methods in vaccinology, in Veterinary Vaccinology, Pastoret P.-P., Blancou, J., Vannier, P., and Verschueren, C., Eds., Elsevier, Amsterdam; New York, 1997, p. 69.
9. Poulsen, O.M., Hau, J., and Kollerup, J., Effect of homogenization and pasteurization on the allergenicity of bovine milk analysed by a murine anaphylactic shock model, Clin. Allergy, 17, 5, 449-458, 1987.
10. Poulsen, O.M., Nielsen, B.R., Basse, A., and Hau, J., Comparison of intestinal anaphylactic reactions in sensitized mice challenged with untreated bovine milk and homogenized bovine milk, Allergy, 45, 321, 1990.
11. Leenaars, M., Adjuvants in Laboratory Animals, Thesis, Erasmus University Rotterdam, Ponsen & Looijen BV., Wageningen, The Netherlands, 1997.
12. Leenaars, P.P.A.M., Hendriksen, C.F.M., De Leeuw, W.A., Carat, F., Delahaut, P., Fischer, R., Halder, M., Hanley, W.C., Hartinger, J., Hau, J., Lindblad, E.B., Nicklas, W., Outschoorn, I.M., and Stewart-Tull, E.S., The production of polyclonal antibodies in laboratory animals, ATLA, 27, 79, 1999.
13. Ramon, G., Sur l’augmentation anormale de l’antitoxine chez les chevaux producteurs de serum antidiphterique, Bull. Soc. Centr. Med. Vet., 101, 227, 1925.
14. Freund, J., Casals, J., and Hosmer, E.P., Sensitization and antibody formation after injection of tubercle bacilli and parafin oil, Proc. Soc. Exp. Biol. Med., 37, 509, 1937.
15. Hohmann, A.W., Freund’s adjuvant and immune responses, in The Use of Immuno-adjuvants in Animals in Australia and New-Zealand, ANZCCART, Glen Osmond, SA, Australia, 1998.
16. Talmage, J. and Dixon, F.J., The influence of adjuvants on the elimination of soluble protein antigens and the associated antibody responses, J. Infect. Dis., 93, 176, 1953.
17. Kittell, C.L., Banks, R.E., and Hadick, C.L., Raised skin lesions in rabbits after immunization, Lab. Anim., 25, 16, 1991.
18. Hau, J., The rabbit as antibody producer - advantages and disadvantages, in Symposium über Zucht, Haltung und Ernährung des Kaninches. Das Kanin als Modell in der Biomed. Forschung. Altromin & Akademi für tierärztliche Fortbildung, 1988, p. 68.
19. Bollen, L.S., Hau, J., Freund’s complete adjuvant has a negative impact on egg laying frequency in immunised chickens, In Vivo, 13, 107, 1999.
20. Colpaert, F.C., Evidence that adjuvant arthritis in the rat is associated with chronic pain, Pain, 28, 201, 1987.
21. Erb, K. and Hau, J., Monoclonal and polyclonal antibodies, in Handbook of Laboratory Animal Science Vol. I, 99, Svendsen, P. and Hau, J., Eds., CRC Press, Boca Raton, FL, 1994, pp. 293-309.
22. Lindblad, E.B. and Hau, J., Escaping from the use of Freund’s complete adjuvant, in Progress in the reduction, refinement and replacement of animal experimentation, Proceedings from the 3rd world congress on alternatives and animal use in the life sciences 1999, Balls, M., van Zeller, A.-M., and Halder, M.E., Eds., Elsevier, Amsterdam, 2000, 1681-1685.
23. Herbert, W.J., Methods for preparation of water-in-oil, and multiple, emulsions for use as antigen adjuvants; and notes on their use in immunization procedures, in Handbook of Experimental Immunology, Weir, D.M., Ed., Blackwell Scientific, Oxford, 1967.
24. Lindblad, E.B. and Sparck, J.V., Basic concepts in the application of immunological adjuvants, Scand. J. Lab. Anim. Sci., 14, 1, 1987.
25. Claassen, E. and Boersma, W.J.A., Characteristics and practical use of new generation adjuvants as an acceptable alternative for Freund’s complete adjuvant, Res. in Immunol., 143, 475, 1992.
26. Stewart-Tull, D.E.S., The Theory and Practical Application of Adjuvants, John Wiley & Sons, New York, 1995.
27. Jennings, V.M., Review of selected adjuvants used in antibody production, ILAR J., 37, 119, 1995.
28. Chapel, H.M. and August, P.J., Report on nine cases of accidental injury to man with Freund’s complete adjuvant, Clin. Exp. Immunol., 24, 558, 1976.
29. Freund, J., Some aspects of active immunization, Ann. Rev. Microbiol., 1, 291, 1947.
30. Bollen, L.S. and Hau, J., Immunoglobulin G in the developing oocytes of the domestic hen and immunospecific antibody response in serum and corresponding egg yolk, In Vivo, 11, 395, 1997.
31. Jensenius, J.C., Andersen, I., Hau, J., Crone, M., and Koch, C., Eggs: conveniently packaged antibodies. Methods for purification of yolk IgG, J. Immunol. Methods, 46, 63, 1981.
32. Svendsen, L., Crowley, A., Ostergaard, L.H., Stodulski, G., and Hau, J., Development and comparison of purification strategies for chicken antibodies from egg yolk, Lab. Anim. Sci., 45, 89, 1995.
33. Svendsen Bollen, L., Crowley, A., Stodulski, G., and Hau, J., Antibody production in rabbits and chickens immunized with human IgG. A comparison of titre and avidity development in rabbit serum, chicken serum and egg yolk using three different adjuvants, J. Immunol. Meth., 27, 191, 113, 1996.
34. Schade, R., Staak, C., Hendriksen, C., Erhard, M., Hugl, H., Koch, G., Larsson, A., Pollmann, W., van Regenmortel, M., Rijke, E., Spielmann, H., Steinbusch, H., and Straughan, D., The production of avian (egg yolk) antibodies: IgY. ECVAM Workshop Report 21, ATLA, 24, 925, 1996.
35. Schade, R., Behn, I., Erhard, M., Hlinak, A. and Staak, C., Eds., Chicken Egg Yolk Antibodies, Production and Application. IgY-Technology. Springer Lab Manual, Berlin, 2001.
36. Hau, J., Westergaard, J.G., Svendsen, P., Bach, A., and Teisner, B., Comparison between pregnancyassociated murine protein-2 (PAMP-2) and human pregnancy-specific beta 1-glycoprotein (SP-1), J. Reprod. Fertil., 60, 115, 1980.
37. Hau, J., Westergaard, J.G., Svendsen, P., Bach, A. and Teisner, B., Comparison of the pregnancyassociated murine protein-1 and human pregnancy zone protein, J. Reprod. Immunol., 3, 341, 1981.
38. Persdotter Hedlund, G. and Hau, J., Oral immunization of chickens using cholera toxin B subunit and Softigen as adjuvants results in high antibody titre in the egg yolk, In Vivo, 15, 384, 2001.
39. Russell, W.M.S. and Burch, R.L., The Principles of Humane Experimental Technique, Methuen & Co. LTD, London, 1959.
40. Cannat, A., Feingold, N., Caffin, J.C., and Serre, A., Studies on the genetic control of murine humoral response to immunization with a peptidoglycan-containing fraction extracted from Brucella melitensis, Ann. Immunol., 130c, 675, 1979.
41. Lifschitz, R., Schwartz, M., and Mozes, E., Specificity of genes controlling immune responsiveness to (T, G)-A-L and (Phe, G)-A-L, Immunol., 41, 339, 1980.
42. Long, D.A., The influence of the thyroid gland upon immune responses of different species to bacterial infection, CIBA Found, Colloq., Endocrinol., 10, 287, 1957.
43. Harboe, N.M.G. and Ingild, A., Immunization, isolation of immunoglobulins, and antibody titre determination, Scand. J. Immunol., 17 Suppl. 10, 245, 1983.
44. Young, C.R. and Atassi, M.Z., Genetic control of antibody response to antigenic sites by increasing the dose of antigen used in immunization, J. Immunogen., 9, 343, 1982.
45. Abraham, L., O’Brien, D., Poulsen, O.M., and Hau, J., The effect of social environment on the production of specific immunoglobulins against an immunogen (human IgG) in mice, in Welfare and Science, Bunyan, J., Ed., 1994, p. 165.
46. Kaplan, P.J., Caperna, T.J., and Garvey, J.S., Bovine serum albumin humoral immune response in aged Fischer 344 rats, Mech. Ageing Dev., 16, 61, 1981.
47. Poulsen, O.M. and Hau, J., Suppression of humoral antibody response during pregnancy in mice, In Vivo, 4, 381, 1990.
48. Bollen, L.S. and Hau, J., Comparison of immunospecific antibody response in young and old chickens immunized with human IgG, Lab. Anim., 33, 71, 1996.
49. Nielsen, B.R., Poulsen, O.M., and Hau, J., Reagin production in mice: effect of subcutaneous and oral sensitization with untreated bovine milk and homogenized bovine milk, In Vivo, 3, 271, 1989.
50. Halliday, L.C. et al., Physiologic and behavioral assessment of rabbits immunized with Freund’s complete adjuvant, Cont. Topics Lab. Anim. Sci., 39, 8, 2000.
51. BVA/FRAME/RSPCA/UFAW Joint Working Group on Refinement: removal of blood from laboratory animals and birds, Lab. Anim., 27, 1-22, 1993.
52. Zutphen van, L.F.M., Baumans, V., and Beynen, A.C., Eds., Principles of Laboratory Animal Science, Elsevier, Amsterdam; New York, 2001, p. 322.
53. Leenaars, P.P.A.M., Koedam, M.A., Wester, P.W., Baumans, V., Claassen, E., and Hendriksen, C.F.M., Assessment of side effects induced by injection of different adjuvant/antigen combinations in rabbits and mice, Lab. Anim., 32, 387, 1998.
54. CCAC, Guidelines on Antibody Production, Ottawa, Ontario, Canada, 2002.
55. Grumstrupp-Scott, J. and Greenhouse, D.D., NIH intramural recommendations for the research use of Freund’s complete adjuvant, ILAR News, 2, 9, 1988.
56. De Kruijf, J. et al., New perspectives on recombinant human antibodies, Immunology Today, 17, 453, 1996.
57. Marx, U., Embleton, M.J., Fischer, R., Gruber, F.P., Hansson, U., Heuer, J., de Leeuw, W.A., Logtenberg, T., Merz, W., Portelle, D., Romette, J.-L., and Straughan, D.W., Monoclonal antibody production. The report and recommendations of ECVAM workshop 23, ATLA, 25, 121, 1997.
58. Johnson, D.R., Murine monoclonal antibody development, in Methods in Molecular Biology, Vol. 51, Antibody Engineering Protocols, Paul, S., Ed., Humane Press, Totowa, NJ, 1995, p. 123.
59. Hendriksen, C.F.M., A call for a European prohibition of monoclonal antibody production by ascites in laboratory animals, ATLA, 26, 523, 1998.
60. Hendriksen, C.F.M., Production of monoclonal antibodies by the ascites method: animal welfare implications, in Proceedings of the Production of Monoclonal Antibodies Workshop, McCardle, J.E. and Lund, C.J., Eds., August 29, 1999, Bologna, Italy, Alternatives Research and Development Foundation, Eden Prairie, 2000, p. 6.
61. Hendriksen, C.F.M. and De Leeuw, W., Production of monoclonal antibodies by the ascites method in laboratory animals, Research in Immunology, 6, 149, 535, 1998.
62. Walvoort, N.C., Assessment of distress through pathological examination, in Replacement, Reduction and Refinement: Present Possibilities and Future Prospects, Hendriksen, C.F.M. and Köeter, H.B.W.M., Eds., Elsevier, Amsterdam; New York, 1991, p. 265.
63. Kuhlmann, I., Kurth, W., and Ruhdel, I., Monoclonal antibodies: in vivo and in vitro production on a laboratory scale, with consideration of the legal aspects of animal protection, ATLA, 17, 73, 1989.
64. Moore, J.M. and Rajan T.V., Pristane retards the clearance of particulate materials from the peritoneal cavity of laboratory mice, J. Immunol. Meth., 173, 273, 1994.
65. O’Driscoll, C.M., Anatomy and physiology of the lymphatics, in Lymphatic Transport of Drugs, Charman, W.N. and Stella, V.J., Eds., CRC Press, Boca Raton, FL, 1992.
66. Gilette, R.W., Alternatives to pristane priming for ascites fluid and monoclonal antibody production, J. Immunol. Meth., 99, 21, 1987.
67. Jackson, L.R., Trudel, L.J., Fox, J.G., and Lipman, N.S., Monoclonal antibody production in murine ascites. I. Clinical and pathological features, Lab. Anim. Sci., 49, 70, 1999.
68. Brodeur, B.R., Tsang, P., and Larose, Y., Parameters affecting ascites tumour formation in mice and monoclonal antibody production, J. Immunol. Meth., 71, 265, 1984.
69. Behammer, W., Kluge, M., Ruschoff, J., and Mannel, D.N., Tumor necrosis factor effects on ascites formation in an experimental tumor model, J. Interferon and Cytokine Research, 14, 403, 1996.
70. De Geus, B. and Hendriksen, C.F.M., Eds., In vivo and in vitro production of monoclonal antibodies:current possibilities and future perspectives, 74th Forum in Immunology, Research in Immunology, 6, 149, 533, 1998.
71. Jackson, L.R., Trudel, L.J., and Lipman, N.S., Small-scale monoclonal antibody production in vitro:methods and resources, in Proceedings of the Production of Monoclonal Antibodies Workshop, McCardle, J.E. and Lund, C.J., Eds., August 29, 1999, Bologna, Italy, Alternatives Research and Development Foundation, Eden Prairie, 2000, p. 16.
72. Falkenberg, F.W., Monoclonal antibody production: problems and solutions, Research in Immunology, 149, 542, 1998.
73. Peterson, N., A comprehensive cost comparison of in vitro and ascites approaches to Mab production, in Proceedings of the Production of Monoclonal Antibodies Workshop, McCardle, J.E. and Lund, C.J., Eds., August 29, 1999, Bologna, Italy, Alternatives Research and Development Foundation, Eden Prairie, 2000, p. 48.
74. National Research Council (NRC), Monoclonal Antibody Production, National Academy Press, Washington, DC, 1999.