Delivery of intravenous treprostinil at low infusion rates using a miniaturized infusion pump in patients with pulmonary arterial hypertension

Journal of Vascular Access

Volumn 7, Issue 3, 2006, Pages 112-117

  Tapson, Victor F ^a   McLaughlin, V V ^b   Gomberg Maitland, M ^c   Widlitz, A C ^d   Krichman, A D ^a   Laliberte, K J ^e   Zaccardelli, D S ^e   Barst, R J ^d  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^c UNIVERSITY OF CHICAGO MEDICAL CENTER   (United States)

^d Columbia University College of Physicians and Surgeons ^*  (United States)

^e UNITED THERAPEUTICS CORPORATION   (United States)

Author keywords

407C; Drug delivery; Miniaturization; Pulmonary arterial hypertension; Remodulin; Treprostinil

Indexed keywords

UNIPROST;

ADULT; ARTICLE; CATHETER OCCLUSION; CLINICAL ARTICLE; CLINICAL FEATURE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEVICE; DIARRHEA; DISEASE SEVERITY; DIZZINESS; DRUG ACTIVITY; DRUG APPROVAL; DRUG EFFICACY; DRUG INFUSION; DRUG SAFETY; DRUG STABILITY; DRUG WITHDRAWAL; DYSPNEA; FATIGUE; FEMALE; FLUSHING; HEADACHE; HEART PALPITATION; HUMAN; INFUSION PUMP; INFUSION RATE; JAW; MALE; MULTICENTER STUDY; NAUSEA; OPEN STUDY; PAIN; PATIENT CODING; PULMONARY HYPERTENSION; ROOM TEMPERATURE; SKIN MANIFESTATION; SYMPTOM; WALKING;

EID: 33750330689     PISSN: 11297298     EISSN: None     Source Type: Journal    
DOI: 10.1177/112972980600700304     Document Type: Article

References (7)

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2. Pulmonary arterial hypertension: Epidemiology, pathobiology, assessment, and therapy. JACC 2004; 43: 1S-90S.
3. Laliberte K, Arneson C, Jeffs R, et al. Pharmacokinetics and steady state bioequivalience of treprostinil sodium (Remodulin®) administered by the intravenous and subcutaneous route to normal volunteers. J Cardiovasc Pharmacol 2004; 44: 209-14.
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5. Tapson VF, Gomberg-Maitland M, McLaughlin VV, et al. Safety and efficacy of intravenous treprostinil for pulmonary arterial hypertension: a prospective, multicenter, open-label 12-week trial. Chest 2006 (in press).
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7. IntraPump Infusion Systems, . 31 May 2006.