Is there a place for activated protein C (Xigris®) in the treatment of severe imported malaria in the adult?;Y a-t-il une place pour la protéine C activée (Xigris®) dans le traitement du paludisme grave d'importation de l'adulte ?

Annales Francaises d'Anesthesie et de Reanimation

Volumn 25, Issue 10, 2006, Pages 1085-1086

  Nau, A ^a   Peytel, E ^a   Petrognani, R ^a  

^a LAVERAN MILITARY TEACHING HOSPITAL   (France)

Author keywords

Drotrecogin alpha (activated); Severe imported malaria

Indexed keywords

ANTIPARASITIC AGENT; DROTRECOGIN; NORADRENALIN; QUININE;

BLOOD CLOTTING DISORDER; DISEASE SEVERITY; HUMAN; LETTER; MALARIA FALCIPARUM; MICROANGIOPATHY; MORTALITY; MULTIPLE ORGAN FAILURE; PLASMODIUM FALCIPARUM; SYSTEMIC DISEASE; TREATMENT INDICATION;

ADULT; ANTI-INFECTIVE AGENTS; HUMANS; MALARIA, FALCIPARUM; MALE; PROTEIN C; RECOMBINANT PROTEINS; SEVERITY OF ILLNESS INDEX; TRAVEL;

EID: 33750328534     PISSN: 07507658     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.annfar.2006.06.011     Document Type: Letter

References (5)

1. World Health Organisation. Severe falciparum malariae. Trans. R. Soc. Trop. Med. Hyg. 94 Suppl 1 (2000) 1-90
2. Saïssy J.M., Rouvin B., and Koulmann P. Le paludisme grave en réanimation en 2003. Med. Trop. 63 (2003) 258-266
3. Bernard G.R., Vincent J.L., Laterre P.F., LaRosa S.P., Dhainaut J.F., Lopez-Rodriguez A., et al. Recombinant human protein C Worldwide Evaluation in Severe Sepsis (PROWESS) study group. Efficacy and safety of recombinant human activated protein C for severe sepsis. N. Engl. J. Med. 344 (2001) 699-709
4. Opal S.M., Garber G.E., LaRose S.P., Maki D.G., Freebairn R.C., Kinasewitz G.T., et al. Systemic host responses in severe sepsis analysed by causative microorganism and treatment effects of drotrecogin alpha (activated). Clin. Infect. Dis. 37 (2003) 50-58
5. Bone R.C., Balk R.A., Cerra F.B., Dellinger R.P., Fein A.M., Knaus W.A., et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. Chest 101 (1992) 1644-1655