Validation of the "L-DOPA test" for diagnosis of restless legs syndrome

Movement Disorders

Volumn 21, Issue 9, 2006, Pages 1333-1339

  Stiasny Kolster, Karin ^a   Kohnen, Ralf ^b   Möller, Jens Carsten ^a   Trenkwalder, Claudia ^c   Oertel, Wolfgang H ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b Inst Med Res Mgmt and Biometr   (Germany)

^c Center of Parkinsonism and Movement Disorders   (Germany)

Author keywords

Diagnosis; L DOPA test; Periodic leg movements (PLM); Polysomnography; Restless legs syndrome

Indexed keywords

BENSERAZIDE PLUS LEVODOPA; DOPAMINE RECEPTOR STIMULATING AGENT; LEVODOPA; RESTEX;

ADULT; AGED; ARTICLE; CLINICAL ARTICLE; CLINICAL PROTOCOL; CONTROLLED STUDY; DIAGNOSTIC ACCURACY; DIAGNOSTIC PROCEDURE; DIAGNOSTIC TEST; DISEASE SEVERITY; DRUG EFFICACY; FEMALE; HUMAN; LEG MOVEMENT; MALE; POLYSOMNOGRAPHY; PREDICTION; PRIORITY JOURNAL; RESTLESS LEGS SYNDROME; SENSITIVITY AND SPECIFICITY; STATISTICAL ANALYSIS; SYMPTOM; VALIDATION PROCESS; VISUAL ANALOG SCALE;

ADMINISTRATION, ORAL; ADULT; AGED; AGED, 80 AND OVER; BENSERAZIDE; COHORT STUDIES; DIAGNOSIS, DIFFERENTIAL; FEMALE; HUMANS; LEVODOPA; MALE; MIDDLE AGED; MOTOR ACTIVITY; PAIN MEASUREMENT; POLYSOMNOGRAPHY; PREDICTIVE VALUE OF TESTS; RESTLESS LEGS SYNDROME;

EID: 33750319131     PISSN: 08853185     EISSN: 15318257     Source Type: Journal    
DOI: 10.1002/mds.20969     Document Type: Article

References (25)

1. Walters AS. Toward a better definition of the restless legs syndrome. The International Restless Legs Syndrome Study Group. Mov Disord 1995;10:634-642.
2. Allen R, Picchietti D, Hening W, et a]. Restless legs syndrome: diagnostic criteria, special considerations, and epidemiology. A report from the restless legs syndrome diagnosis and epidemiology workshop at the National Institute of Health. Sleep Med 2003;4: 101-119.
3. Lesage S, Hening WA. The restless legs syndrome and periodic limb movement disorder: a review of management. Semin Neurol 2004;24:249-259.
4. Stiasny K, Oertel WH, Trenkwalder C. Clinical symptomatology and treatment of restless legs syndrome and periodic limb movement disorder. Sleep Med Rev 2002;6:253-265.
5. Hening WA, Allen RR, Earley CJ, Picchietti DL, Silber MH. An update on the dopaminergic treatment of restless legs syndrome and periodic limb movement disorder. An American Academy of Sleep Medicine interim review. Sleep 2004;27: 560-583.
6. Silber MH, Ehrenberg BL, Allen RP, et al. An algorithm for the management of restless legs syndrome. Mayo Clin Proc 2004;79: 916-922.
7. Garcia-Borreguero D, Odin P, Schwarz C. Restless legs syndrome: an overview of the current understanding and management. Acta Neurol Scand 2004;109:303-317.
8. Trenkwalder C, Stiasny K, Pollmächer T, et al. L-dopa therapy of uremic and idiopathic restless legs syndrome: a double-blind, crossover trial. Sleep 1995;18:681-688.
9. Benes H, Kurella B, Kummer J, et al. Rapid onset of action of levodopa in restless legs syndrome: a double-blind, randomised, multi-center, crossover trial. Sleep 1999;22:1073-1081.
10. Saletu M, Anderer P, Högl B, et al. Acute double-blind, placebo-controlled sleep laboratory and clinical follow-up studies with a combination treatment of rr-L-dopa and sr-L-dopa in restless legs syndrome. J Neural Transm 2003;110:611-626.
11. Atlas Task Force of the American Sleep Disorders Association. Recording and scoring leg movements. Sleep 1993;16:748-759.
12. Pollmächer T, Schulz H. Periodic leg movements (PLM): their relationship to sleep stages. Sleep 1993;16:572-577.
13. Atlas Task Force of the American Sleep Disorders Association. Guilleminault C, chairman. EEG arousals: scoring rules and examples. Sleep 1992;15:173-184.
14. Rechtschaffen A, Kales A. A manual of standardized terminology, techniques, and scoring system for sleep stages of human subjects. Los Angeles: UCLA Brain Information Service/Brain Research Institute; 1968.
15. National Institute of Mental Health. 028 CGI. Clinical Global Impressions. Rockville: MD: National Institute for Mental Health; 1976.
16. The International Restless Legs Syndrome Study Group. Validation of the International Restless Legs Syndrome Study Group rating scale for restless legs. Sleep Med 2003;4:121-132.
17. Hening W, Allen R. Restless legs syndrome (RLS): the continuing development of diagnostic standards and severity measures [editorial]. Sleep Med 2003;4:95-97.
18. Kohnen R, Oertel WH, Stiasny-Kolster K, Benes H, Trenkwalder C. Severity rating of restless legs syndrome: validation of the RLS-6 scales [abstract]. Sleep 2004;27(Suppl. 1):A304.
19. Dunn G. Statistics in Psychiatry. London: Arnold; 2002.
20. DeLong ER, De Long DM, Clarke Pearson DL. Comparing the areas under two or more correlated receiver operating characteristic curves: a nonparametric approach. Biometrics 1988;44:837-845.
21. Sevim S, Dogu O, Kaleagasi H, et al. Correlation of anxiety and depression symptoms in patients with restless legs syndrome: a population based survey. J Neurol Neurosurg Psychiatry 2004;75: 226-230.
22. Winkelmann J, Prager M, Lieb R, et al. "Anxietas Tibiarum" - Depression and anxiety disorders in patients with restless legs syndrome. J Neurol 2005;252:67-71.
23. Mahowald MW. Assessment of periodic leg movements is not an essential component of an overnight sleep study. Am J Respir Crit Care Med 2001;164:1340-1341.
24. Michaud M, Paquet J, Lavigne G, Desautels A, Montplaisir J. Sleep laboratory diagnosis of restless legs syndrome. Eur Neurol 2001;48:108-113.
25. Atlas Task Force of the American Sleep Disorders Association (ASDA). The International Classification of Sleep Disorders - diagnostic and coding manual. Rochester, MN: American Sleep Disorders Association; 2005.