Microchips and single-photon avalance diodes for DNA separation with high sensitivity

Electrophoresis

Volumn 27, Issue 19, 2006, Pages 3797-3804

  Rech, Ivan ^a   Cova, Sergio ^a,b   Restelli, Alessandro ^a   Ghioni, Massimo ^a,b   Chiari, Marcella ^c   Cretich, Marina ^c  

^a POLITECNICO DI MILANO   (Italy)

^b Micron Photon Devices   (Italy)

^c CNR   (Italy)

Author keywords

DNA separation; Electrophoresis; Microchip; Single photon avalance diode

Indexed keywords

AVALANCHE DIODES; DNA; MICROELECTRONICS; MICROPROCESSOR CHIPS; OLIGONUCLEOTIDES; PARTICLE BEAMS; PHOTOMULTIPLIERS; PHOTONS;

DNA ANALYSIS; DNA SEPARATION; HIGH SENSITIVITY; MICROCHIP; MODERN TECHNIQUES; PROTEIN ANALYSIS; PROTEIN SEPARATIONS; SINGLE PHOTON AVALANCHE DIODE; SINGLE PHOTONS; SINGLE-PHOTON AVALANCE DIODE;

ELECTROPHORESIS;

CYSTEINE; DNA FRAGMENT; OLIGONUCLEOTIDE; SILICON;

ARTICLE; COMPUTER INTERFACE; COMPUTER PROGRAM; CONTROLLED STUDY; DATA ANALYSIS; DIODE; DNA DETERMINATION; ELECTRIC POTENTIAL; ELECTRONICS; FLUORESCENCE ANALYSIS; MATERIAL COATING; MATHEMATICAL ANALYSIS; MICROCHIP ELECTROPHORESIS; PHOTON; PROTEIN ANALYSIS; SENSITIVITY ANALYSIS; SEPARATION TECHNIQUE;

EID: 33750268533     PISSN: 01730835     EISSN: 15222683     Source Type: Journal    
DOI: 10.1002/elps.200600144     Document Type: Article

References (26)

1. Mastrangelo, C. H., Burns, M. A., Burke, D. T, Proc. IEEE 1998, 86, 1769-1787.
2. Cova, S., Ghioni, M., Lacaita, A., Samori, C., Zappa, F., Appl. Opt. 1996, 35, 1956-1976.
3. Cova, S., Longoni, A., Andreoni, A., Rev. Sci. Instrum. 1981, 52, 408-412.
4. Cova, S., Ghioni, M., Lotito, A., Rech, I., Zappa, F., J. Mod. Opt. 2004, 51, 1267-1288.
5. Gulinatti, A., Maccagnani, P., Rech, I., Ghioni, M., Cova, S., Electron. Lett. 2005, 41, 272-274.
6. Dautet, H., Deschamps, P., Dion, B., MacGregor, A. D. et al., Appl. Opt. 1993, 32, 3894-3900.
7. Ghioni, M., Cova, S., Lacaita, A., Ripamonti, G., Electron. Left. 1988, 24, 1476-1477.
8. Lacaita, A., Ghioni, M., Cova, S., Electron. Lett. 1989, 25, 841-843.
9. Lacaita, A., Cova, S., Ghioni, M., Zappa F., IEEE Electron Device Lett. 1993, 14, 360-362.
10. Vasile, S., Gotoshkar, P., Farrell, R., Sdrulla, D., IEEE Trans. Nucleic Sci. 1998, 45, 720-723.
11. Rochas, A., Gani, M., Furrer, B., Ribordy, G. et al., Rev. Sci. Instr. 2003, 74, 3263-3270.
12. Zhang, J., Voss, K. O., Shaw, D. F., Roos, K. P. et al., Nucleic Acids Res. 1999, 27, E36.
13. Dovichi, N. J., Zhang, J. Z., Methods Mol. Biol. 2001, 162, 85-94.
14. McWhorter, S., Soper, S. S., Electrophoresis 2000, 21, 1267-1280.
15. Chabinyc, M. L., Chiu, D. T., McDonald, J. C., Stroock, A. D. et al., Anal. Chem. 2001, 73, 4491-4498.
16. Chiari, M., Cretich, M., Damin, F., Cerotti, L., Consonni, R., Electrophoresis 2000, 21, 909-916.
17. Zappa, F., Lotto, A., Giudice, A. C., Cova, S., Ghioni, M., IEEE J. Solid-State Circuits 2003, 38, 1298-1301.
18. US Pat. 6541752 B2, invs.: Zappa, F., Cova, S., Ghioni, M., 2003 (priority March 9, 2000); European patent application no. 01200852.2-2217, 2001.
19. Patankar, N. A., Howard, H. H., Anal. Chem. 1998, 70, 1870-1881.
20. Dolnik, V., Electrophoresis 2004, 3589-3601.
21. Belder, D., Ludwig, M., Electrophoresis 2003, 24, 3595-3606.
22. Geschke, O., Klank, H., Telleman, R, Microsystem Engineering of Lab-on-chip Devices, Wiley-VCH, Weinheim 2004.
23. Huang, X., Gordon, M. J., Zara, R. N., Anal. Chem. 1988, 60, 1837-1838.
24. Ren, X., Bachman, M., Sims, C., Li, G. P., Albritton, N., J. Chromatogr. B 2001, 762, 117-125.
25. Cretich, M., Chiari, M., Rech, I., Cova, S., Electrophoresis 2003, 24, 3793-3799.
26. Wilmshurst, T. H., Signal Recovery from Noise in Electronic Instrumentation, IOP Publishing Ltd., Bristol 1990, Chapter 10.