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Volumn 12, Issue 37, 2006, Pages 5932-5940

Complementary analysis of microsatellite tumor profile and mismatch repair defects in colorectal carcinomas

Author keywords

Colon carcinoma; Hereditary non polyposis colon cancer; Microsatellites; Mismatch repair

Indexed keywords

B RAF KINASE; DNA; FLUOROURACIL; K RAS PROTEIN; PROTEIN MLH1;

EID: 33750237434     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v12.i37.5932     Document Type: Review
Times cited : (16)

References (68)
  • 3
    • 0030592517 scopus 로고    scopus 로고
    • Lessons from hereditary colorectal cancer
    • Kinzler KW, Vogelstein B. Lessons from hereditary colorectal. cancer. Cell 1996; 87:159-170
    • (1996) Cell , vol.87 , pp. 159-170
    • Kinzler, K.W.1    Vogelstein, B.2
  • 4
    • 0032525214 scopus 로고    scopus 로고
    • Microsatellite instability in human solid tumors
    • Arzimanoglou II, Gilbert F, Barber HR. Microsatellite instability in human solid tumors. Cancer 1998; 82:1808-1820
    • (1998) Cancer , vol.82 , pp. 1808-1820
    • Arzimanoglou, I.I.1    Gilbert, F.2    Barber, H.R.3
  • 5
    • 0035132202 scopus 로고    scopus 로고
    • Histopathological identification of colon cancer with microsatellite instability
    • Alexander J, Watanabe T, Wu TT, Rashid A, Li S, Hamilton SR. Histopathological identification of colon cancer with microsatellite instability. Am J Pathol 2001; 158: 527-535
    • (2001) Am J Pathol , vol.158 , pp. 527-535
    • Alexander, J.1    Watanabe, T.2    Wu, T.T.3    Rashid, A.4    Li, S.5    Hamilton, S.R.6
  • 6
    • 0037381250 scopus 로고    scopus 로고
    • The clinical importance and prognostic implications of microsatellite instability in sporadic cancer
    • Lawes DA, SenGupta S, Boulos PB. The clinical importance and prognostic implications of microsatellite instability in sporadic cancer. Eur J Surg Oncol 2003; 29: 201-212
    • (2003) Eur J Surg Oncol , vol.29 , pp. 201-212
    • Lawes, D.A.1    SenGupta, S.2    Boulos, P.B.3
  • 7
    • 0030883915 scopus 로고    scopus 로고
    • Common patterns of genetic evolution in human solid tumors
    • Shackney SE, Shankey TV. Common patterns of genetic evolution in human solid tumors. Cytometry 1997; 29: 1-27
    • (1997) Cytometry , vol.29 , pp. 1-27
    • Shackney, S.E.1    Shankey, T.V.2
  • 9
    • 0029089259 scopus 로고
    • Hereditary nonpolyposis colorectal cancer: The syndrome, the genes, and historical perspectives
    • Marra G, Boland CR. Hereditary nonpolyposis colorectal cancer: the syndrome, the genes, and historical perspectives. J Natl Cancer Inst 1995; 87: 1114-1125
    • (1995) J Natl Cancer Inst , vol.87 , pp. 1114-1125
    • Marra, G.1    Boland, C.R.2
  • 10
    • 0028276666 scopus 로고
    • Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite sequences
    • Kim H, Jen J, Vogelstein B, Hamilton SR. Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite sequences. Am J Pathol 1994; 145:148-156
    • (1994) Am J Pathol , vol.145 , pp. 148-156
    • Kim, H.1    Jen, J.2    Vogelstein, B.3    Hamilton, S.R.4
  • 11
    • 0022978562 scopus 로고
    • Histopathology of colorectal carcinomas and adenomas in cancer family syndrome
    • Mecklin JP, Sipponen P, Jarvinen HJ. Histopathology of colorectal carcinomas and adenomas in cancer family syndrome. Dis Colon Rectum 1986; 29: 849-853
    • (1986) Dis Colon Rectum , vol.29 , pp. 849-853
    • Mecklin, J.P.1    Sipponen, P.2    Jarvinen, H.J.3
  • 12
    • 0038235154 scopus 로고    scopus 로고
    • Sporadic colorectal cancers with defective mismatch repair display a number of specific morphological characteristics: Relationship between the expression of hMLH1 and hMSH2 proteins and clinicopathological features of 273 adenocarcinomas
    • Chapusot C, Martin L, Mungra N, Rageot D, Bouvier AM, Bonithon Kopp C, Ponnelle T, Faivre J, Piard F. Sporadic colorectal cancers with defective mismatch repair display a number of specific morphological characteristics: relationship between the expression of hMLH1 and hMSH2 proteins and clinicopathological features of 273 adenocarcinomas. Histopathology 2003; 43: 40-47
    • (2003) Histopathology , vol.43 , pp. 40-47
    • Chapusot, C.1    Martin, L.2    Mungra, N.3    Rageot, D.4    Bouvier, A.M.5    Bonithon Kopp, C.6    Ponnelle, T.7    Faivre, J.8    Piard, F.9
  • 14
    • 0029879384 scopus 로고    scopus 로고
    • Microsatellites and PCR genomic analysis
    • Koreth J, O'Leary JJ, O'D McGee J. Microsatellites and PCR genomic analysis. J Pathol 1996; 178: 239-248
    • (1996) J Pathol , vol.178 , pp. 239-248
    • Koreth, J.1    O'Leary, J.J.2    O'D McGee, J.3
  • 15
    • 0029841222 scopus 로고    scopus 로고
    • Setting microsatellites free
    • Boland CR. Setting microsatellites free. Nat Med 1996; 2: 972-974
    • (1996) Nat Med , vol.2 , pp. 972-974
    • Boland, C.R.1
  • 16
    • 0029372742 scopus 로고
    • Microsatellite instability. Shifting concepts in tumorigenesis
    • Brentnall TA. Microsatellite instability. Shifting concepts in tumorigenesis. Am J Pathol 1995; 147: 561-563
    • (1995) Am J Pathol , vol.147 , pp. 561-563
    • Brentnall, T.A.1
  • 17
    • 0027314411 scopus 로고
    • Microsatellite instability in cancer of the proximal colon
    • Thibodeau SN, Bren G, Schaid D. Microsatellite instability in cancer of the proximal colon. Science 1993; 260: 816-819
    • (1993) Science , vol.260 , pp. 816-819
    • Thibodeau, S.N.1    Bren, G.2    Schaid, D.3
  • 19
    • 0033837572 scopus 로고    scopus 로고
    • Designing a molecular analysis of clonality in tumours
    • Diaz-Cano SJ. Designing a molecular analysis of clonality in tumours. J Pathol 2000; 191: 343-344
    • (2000) J Pathol , vol.191 , pp. 343-344
    • Diaz-Cano, S.J.1
  • 21
    • 0035673125 scopus 로고    scopus 로고
    • Are PCR artifacts in microdissected samples preventable?
    • Diaz-Cano SJ. Are PCR artifacts in microdissected samples preventable? Hum Pathol 2001; 32:1415-1416
    • (2001) Hum Pathol , vol.32 , pp. 1415-1416
    • Diaz-Cano, S.J.1
  • 22
    • 0032414656 scopus 로고    scopus 로고
    • Multiple genetic diagnoses from single cells using multiplex PCR: Reliability and allele dropout
    • Findlay I, Matthews P, Quirke P. Multiple genetic diagnoses from single cells using multiplex PCR: reliability and allele dropout. Prenat Diagn 1998; 18:1413-1421
    • (1998) Prenat Diagn , vol.18 , pp. 1413-1421
    • Findlay, I.1    Matthews, P.2    Quirke, P.3
  • 23
    • 0030089526 scopus 로고    scopus 로고
    • Increasing the denaturation temperature during the first cycles of amplification reduces allele dropout from single cells for preimplantation genetic diagnosis
    • Ray PF, Handyside AH. Increasing the denaturation temperature during the first cycles of amplification reduces allele dropout from single cells for preimplantation genetic diagnosis. Mol Hum Reprod 1996; 2: 213-218
    • (1996) Mol Hum Reprod , vol.2 , pp. 213-218
    • Ray, P.F.1    Handyside, A.H.2
  • 24
    • 0345516014 scopus 로고    scopus 로고
    • DNA extraction from formalin-fixed, paraffin-embedded tissues: Protein digestion as a limiting step for retrieval of high-quality DNA
    • Diaz-Cano SJ, Brady SP. DNA extraction from formalin-fixed, paraffin-embedded tissues: protein digestion as a limiting step for retrieval of high-quality DNA. Diagn Mol Pathol 1997; 6: 342-346
    • (1997) Diagn Mol Pathol , vol.6 , pp. 342-346
    • Diaz-Cano, S.J.1    Brady, S.P.2
  • 25
    • 0034122741 scopus 로고    scopus 로고
    • Molecular evolution and intratumor heterogeneity by topographic compartments in muscle-invasive transitional cell carcinoma of the urinary bladder
    • Diaz-Cano SJ, Blanes A, Rubio J, Matilla A, Wolfe HJ. Molecular evolution and intratumor heterogeneity by topographic compartments in muscle-invasive transitional cell carcinoma of the urinary bladder. Lab Invest 2000; 80:279-289
    • (2000) Lab Invest , vol.80 , pp. 279-289
    • Diaz-Cano, S.J.1    Blanes, A.2    Rubio, J.3    Matilla, A.4    Wolfe, H.J.5
  • 26
    • 0032534069 scopus 로고    scopus 로고
    • A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: Development of international criteria for the determination of microsatellite instability in colorectal cancer
    • Boland CR, Thibodeau SN, Hamilton SR, Sidransky D, Eshleman JR, Burt RW, Meltzer SJ, Rodriguez-Bigas MA, Fodde R, Ranzani GN, Srivastava S. A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res 1998; 58: 5248-5257
    • (1998) Cancer Res , vol.58 , pp. 5248-5257
    • Boland, C.R.1    Thibodeau, S.N.2    Hamilton, S.R.3    Sidransky, D.4    Eshleman, J.R.5    Burt, R.W.6    Meltzer, S.J.7    Rodriguez-Bigas, M.A.8    Fodde, R.9    Ranzani, G.N.10    Srivastava, S.11
  • 29
    • 0032730774 scopus 로고    scopus 로고
    • Genetic susceptibility to nonpolyposis colorectal cancer
    • Lynch HT, de la Chapelle A. Genetic susceptibility to nonpolyposis colorectal cancer. J Med Genet 1999; 36: 801-818
    • (1999) J Med Genet , vol.36 , pp. 801-818
    • Lynch, H.T.1    de la Chapelle, A.2
  • 30
    • 0025848680 scopus 로고
    • The International Collaborative Group on Hereditary Non-Polyposis Colorectal Cancer (ICG-HNPCC)
    • Vasen HF, Mecklin JP, Khan PM, Lynch HT. The International Collaborative Group on Hereditary Non-Polyposis Colorectal Cancer (ICG-HNPCC). Dis Colon Rectum 1991; 34:424-425
    • (1991) Dis Colon Rectum , vol.34 , pp. 424-425
    • Vasen, H.F.1    Mecklin, J.P.2    Khan, P.M.3    Lynch, H.T.4
  • 33
    • 0036569940 scopus 로고    scopus 로고
    • Mutations at coding repeat sequences in mismatch repair-deficient human cancers: Toward a new concept of target genes for instability
    • Duval A, Hamelin R. Mutations at coding repeat sequences in mismatch repair-deficient human cancers: toward a new concept of target genes for instability. Cancer Res 2002; 62: 2447-2454
    • (2002) Cancer Res , vol.62 , pp. 2447-2454
    • Duval, A.1    Hamelin, R.2
  • 34
    • 0035054387 scopus 로고    scopus 로고
    • Deficient DNA mismatch repair: A common etiologic factor for colon cancer
    • Peltomaki P. Deficient DNA mismatch repair: a common etiologic factor for colon cancer. Hum Mol Genet 2001; 10: 735-740
    • (2001) Hum Mol Genet , vol.10 , pp. 735-740
    • Peltomaki, P.1
  • 35
    • 0035101436 scopus 로고    scopus 로고
    • DNA mismatch repair and cancer
    • Peltomaki P. DNA mismatch repair and cancer. Mutat Res 2001; 488: 77-85
    • (2001) Mutat Res , vol.488 , pp. 77-85
    • Peltomaki, P.1
  • 38
    • 2942514668 scopus 로고    scopus 로고
    • Both BRAF and KRAS mutations are rare in colorectal carcinomas from patients with hereditary nonpolyposis colorectal cancer
    • Miyaki M, Iijima T, Yamaguchi T, Kadofuku T, Funata N, Mori T. Both BRAF and KRAS mutations are rare in colorectal carcinomas from patients with hereditary nonpolyposis colorectal cancer. Cancer Lett 2004; 211: 105-109
    • (2004) Cancer Lett , vol.211 , pp. 105-109
    • Miyaki, M.1    Iijima, T.2    Yamaguchi, T.3    Kadofuku, T.4    Funata, N.5    Mori, T.6
  • 39
    • 0032938961 scopus 로고    scopus 로고
    • Clinicopathologic and carcinogenetic appraisal of DNA replication error in sporadic T3N0M0 stage colorectal cancer after curative resection
    • Liang JT, Chang KJ, Chen JC, Lee CC, Cheng YM, Hsu HC, Chien CT, Wang SM. Clinicopathologic and carcinogenetic appraisal of DNA replication error in sporadic T3N0M0 stage colorectal cancer after curative resection. Hepatogastroenterology 1999; 46: 883-890
    • (1999) Hepatogastroenterology , vol.46 , pp. 883-890
    • Liang, J.T.1    Chang, K.J.2    Chen, J.C.3    Lee, C.C.4    Cheng, Y.M.5    Hsu, H.C.6    Chien, C.T.7    Wang, S.M.8
  • 40
    • 33644828368 scopus 로고    scopus 로고
    • Expression of mlh1/msh2 in colo-rectal adenocarcinomas: SAGE/microarray profile and tumor phenotype
    • (Abstract)
    • Jimenez-Martin JJ, Miranda MT, Blanes A, Diaz-Cano SJ. Expression of mlh1/msh2 in colo-rectal adenocarcinomas: SAGE/microarray profile and tumor phenotype. Lab Invest 2003; 83: 296A (Abstract)
    • (2003) Lab Invest , vol.83
    • Jimenez-Martin, J.J.1    Miranda, M.T.2    Blanes, A.3    Diaz-Cano, S.J.4
  • 41
    • 33644820486 scopus 로고    scopus 로고
    • Abscence of the physiologic cellular kinetic balance and down-regulation of mlh1/msh2 characterize deep topographic compartments of colo-rectal adenocarcinomas
    • (Abstract)
    • Blanes A, Jimenez-Martin JJ, Miranda MT, Diaz-Cano SJ. Abscence of the physiologic cellular kinetic balance and down-regulation of mlh1/msh2 characterize deep topographic compartments of colo-rectal adenocarcinomas. Lab Invest 2003; 83:114A-115A (Abstract)
    • (2003) Lab Invest , vol.83
    • Blanes, A.1    Jimenez-Martin, J.J.2    Miranda, M.T.3    Diaz-Cano, S.J.4
  • 42
    • 0032032682 scopus 로고    scopus 로고
    • Somatic frameshift mutations in DNA mismatch repair and proapoptosis genes in hereditary nonpolyposis colorectal cancer
    • Yamamoto H, Sawai H, Weber TK, Rodriguez-Bigas MA, Perucho M. Somatic frameshift mutations in DNA mismatch repair and proapoptosis genes in hereditary nonpolyposis colorectal cancer. Cancer Res 1998; 58: 997-1003
    • (1998) Cancer Res , vol.58 , pp. 997-1003
    • Yamamoto, H.1    Sawai, H.2    Weber, T.K.3    Rodriguez-Bigas, M.A.4    Perucho, M.5
  • 44
    • 0346396341 scopus 로고    scopus 로고
    • Microsatellite instability in colon cancer
    • author reply 1774-1776
    • Jimenez JJ, Blanes A, Diaz-Cano SJ. Microsatellite instability in colon cancer. N Engl J Med 2003; 349: 1774-1776; author reply 1774-1776
    • (2003) N Engl J Med , vol.349 , pp. 1774-1776
    • Jimenez, J.J.1    Blanes, A.2    Diaz-Cano, S.J.3
  • 47
    • 0035126870 scopus 로고    scopus 로고
    • Genetic testing for cancer predisposition
    • Eng C, Hampel H, de la Chapelle A. Genetic testing for cancer predisposition. Annu Rev Med 2001; 52:371-400
    • (2001) Annu Rev Med , vol.52 , pp. 371-400
    • Eng, C.1    Hampel, H.2    de la Chapelle, A.3
  • 48
    • 0033825587 scopus 로고    scopus 로고
    • Sensitivity and specificity of clinical criteria for hereditary non-polyposis colorectal cancer associated mutations in MSH2 and MLH1
    • Syngal S, Fox EA, Eng C, Kolodner RD, Garber JE. Sensitivity and specificity of clinical criteria for hereditary non-polyposis colorectal cancer associated mutations in MSH2 and MLH1. J Med Genet 2000; 37: 641-645
    • (2000) J Med Genet , vol.37 , pp. 641-645
    • Syngal, S.1    Fox, E.A.2    Eng, C.3    Kolodner, R.D.4    Garber, J.E.5
  • 49
    • 0034950515 scopus 로고    scopus 로고
    • American Gastroenterological Association medical position statement: Hereditary colorectal cancer and genetic testing
    • American Gastroenterological Association
    • American Gastroenterological Association. American Gastroenterological Association medical position statement: hereditary colorectal cancer and genetic testing. Gastroenterology 2001; 121: 195-197
    • (2001) Gastroenterology , vol.121 , pp. 195-197
  • 50
    • 0034038956 scopus 로고    scopus 로고
    • Hereditary nonpolyposis colorectal cancer: A call for attention
    • Syngal S. Hereditary nonpolyposis colorectal cancer: a call for attention. J Clin Oncol 2000; 18: 2189-2192
    • (2000) J Clin Oncol , vol.18 , pp. 2189-2192
    • Syngal, S.1
  • 51
    • 0036187460 scopus 로고    scopus 로고
    • Loss of DNA mismatch repair proteins in skin tumors from patients with Muir-Torre syndrome and MSH2 or MLH1 germline mutations: Establishment of immunohistochemical analysis as a screening test
    • Mathiak M, Rutten A, Mangold E, Fischer HP, Ruzicka T, Friedl W, Propping P, Kruse R. Loss of DNA mismatch repair proteins in skin tumors from patients with Muir-Torre syndrome and MSH2 or MLH1 germline mutations: establishment of immunohistochemical analysis as a screening test. Am J Surg Pathol 2002; 26: 338-343
    • (2002) Am J Surg Pathol , vol.26 , pp. 338-343
    • Mathiak, M.1    Rutten, A.2    Mangold, E.3    Fischer, H.P.4    Ruzicka, T.5    Friedl, W.6    Propping, P.7    Kruse, R.8
  • 55
    • 0029070143 scopus 로고
    • Isolation of an hMSH2-p160 heterodimer that restores DNA mismatch repair to turnor cells
    • Drummond JT, Li GM, Longley MJ, Modrich P. Isolation of an hMSH2-p160 heterodimer that restores DNA mismatch repair to turnor cells. Science 1995; 268: 1909-1912
    • (1995) Science , vol.268 , pp. 1909-1912
    • Drummond, J.T.1    Li, G.M.2    Longley, M.J.3    Modrich, P.4
  • 56
    • 0024396565 scopus 로고
    • DNA mismatch correction in a defined system
    • Lahue RS, Au KG, Modrich P. DNA mismatch correction in a defined system. Science 1989; 245: 160-164
    • (1989) Science , vol.245 , pp. 160-164
    • Lahue, R.S.1    Au, K.G.2    Modrich, P.3
  • 57
    • 0028128601 scopus 로고
    • MLH1, PMS1, and MSH2 interactions during the initiation of DNA mismatch repair in yeast
    • Prolla TA, Pang Q, Alani E, Kolodner RD, Liskay RM. MLH1, PMS1, and MSH2 interactions during the initiation of DNA mismatch repair in yeast. Science 1994; 265: 1091-1093
    • (1994) Science , vol.265 , pp. 1091-1093
    • Prolla, T.A.1    Pang, Q.2    Alani, E.3    Kolodner, R.D.4    Liskay, R.M.5
  • 58
    • 0035812238 scopus 로고    scopus 로고
    • Sporadic colorectal cancers with microsatellite instability and their possible origin in hyperplastic polyps and serrated adenomas
    • Hawkins NJ, Ward RL. Sporadic colorectal cancers with microsatellite instability and their possible origin in hyperplastic polyps and serrated adenomas. J Natl Cancer Inst 2001; 93: 1307-1313
    • (2001) J Natl Cancer Inst , vol.93 , pp. 1307-1313
    • Hawkins, N.J.1    Ward, R.L.2
  • 61
    • 0037096801 scopus 로고    scopus 로고
    • Evaluation of microsatellite instability and immunohistochemistry for the prediction of germ-line MSH2 and MLH1 mutations in hereditary nonpolyposis colon cancer families
    • Wahlberg SS, Schmeits J, Thomas G, Loda M, Garber J, Syngal S, Kolodner RD, Fox E. Evaluation of microsatellite instability and immunohistochemistry for the prediction of germ-line MSH2 and MLH1 mutations in hereditary nonpolyposis colon cancer families. Cancer Res 2002; 62: 3485-3492
    • (2002) Cancer Res , vol.62 , pp. 3485-3492
    • Wahlberg, S.S.1    Schmeits, J.2    Thomas, G.3    Loda, M.4    Garber, J.5    Syngal, S.6    Kolodner, R.D.7    Fox, E.8
  • 62
    • 0033986545 scopus 로고    scopus 로고
    • p53 gene mutation, microsatellite instability and adjuvant chemotherapy: Impact on survival of 388 patients with Dukes' C colon carcinoma
    • Elsaleh H, Powell B, Soontrapornchai P, Joseph D, Goria F, Spry N, Iacopetta B. p53 gene mutation, microsatellite instability and adjuvant chemotherapy: impact on survival of 388 patients with Dukes' C colon carcinoma. Oncology 2000; 58:52-59
    • (2000) Oncology , vol.58 , pp. 52-59
    • Elsaleh, H.1    Powell, B.2    Soontrapornchai, P.3    Joseph, D.4    Goria, F.5    Spry, N.6    Iacopetta, B.7
  • 63
    • 0037010411 scopus 로고    scopus 로고
    • DNA markers predicting benefit from adjuvant fluorouracil in patients with colon cancer: A molecular study
    • Barratt PL, Seymour MT, Stenning SP, Georgiades I, Walker C, Birbeck K, Quirke P. DNA markers predicting benefit from adjuvant fluorouracil in patients with colon cancer: a molecular study. Lancet 2002; 360:1381-1391
    • (2002) Lancet , vol.360 , pp. 1381-1391
    • Barratt, P.L.1    Seymour, M.T.2    Stenning, S.P.3    Georgiades, I.4    Walker, C.5    Birbeck, K.6    Quirke, P.7
  • 65
    • 0035428087 scopus 로고    scopus 로고
    • Microsatellite instability is a predictive marker for survival benefit from adjuvant chemotherapy in a population-based series of stage III colorectal carcinoma
    • Elsaleh H, Iacopetta B. Microsatellite instability is a predictive marker for survival benefit from adjuvant chemotherapy in a population-based series of stage III colorectal carcinoma. Clin Colorectal Cancer 2001; 1: 104-109
    • (2001) Clin Colorectal Cancer , vol.1 , pp. 104-109
    • Elsaleh, H.1    Iacopetta, B.2
  • 66
    • 0037145305 scopus 로고    scopus 로고
    • High-frequency microsatellite instability predicts better chemosensitivity to high-dose 5-fluorouracil plus leucovorin chemotherapy for stage IV sporadic colorectal cancer after palliative bowel resection
    • Liang JT, Huang KC, Lai HS, Lee PH, Cheng YM, Hsu HC, Cheng AL, Hsu CH, Yeh KH, Wang SM, Tang C, Chang KJ. High-frequency microsatellite instability predicts better chemosensitivity to high-dose 5-fluorouracil plus leucovorin chemotherapy for stage IV sporadic colorectal cancer after palliative bowel resection. Int J Cancer 2002; 101: 519-525
    • (2002) Int J Cancer , vol.101 , pp. 519-525
    • Liang, J.T.1    Huang, K.C.2    Lai, H.S.3    Lee, P.H.4    Cheng, Y.M.5    Hsu, H.C.6    Cheng, A.L.7    Hsu, C.H.8    Yeh, K.H.9    Wang, S.M.10    Tang, C.11    Chang, K.J.12
  • 67
    • 0036319027 scopus 로고    scopus 로고
    • Increased sensitivity of colorectal cancer cell lines with microsatellite instability to 5-fluorouracil in vitro
    • Chen X, Lai MD, Huang Q. Increased sensitivity of colorectal cancer cell lines with microsatellite instability to 5-fluorouracil in vitro. Chin Med J (Engl) 2002; 115:1048-1052
    • (2002) Chin Med J (Engl) , vol.115 , pp. 1048-1052
    • Chen, X.1    Lai, M.D.2    Huang, Q.3


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