A cyclic model for particle motion in the pulmonary acinus

Journal of Fluid Mechanics

Volumn 567, Issue , 2006, Pages 157-184

  Haber, S ^a   Tsuda, A ^b  

^a TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MATERIALS; CHAOS THEORY; INCOMPRESSIBLE FLOW; SHEAR FLOW;

LUNG ALVEOLI; PARTICLE MOTION; PULMONARY ACINUS;

FLOW OF SOLIDS;

BIOLOGICAL MATERIALS; CHAOS THEORY; FLOW OF SOLIDS; INCOMPRESSIBLE FLOW; SHEAR FLOW;

INCOMPRESSIBLE FLOW; PARTICLE MOTION; SHEAR FLOW;

EID: 33750215653     PISSN: 00221120     EISSN: 14697645     Source Type: Journal    
DOI: 10.1017/S0022112006002345     Document Type: Article

References (31)

1. Aref, H. 1984 Stirring by chaotic advection. J. Fluid Mech. 143, 1-21.
2. Aref, H. & Balachandar, S. 1986 Chaotic advection in a Stokes flow. Phys. Fluids 29, 3515-3521.
3. Ballal, B. Y. & Rivlin, R. S. 1976 Flow of a Newtonian fluid between eccentric rotating cylinders: Inertial effects. Arch. Rat. Mech. Anal. 62, 237-294.
4. Darquenne, C. & Pavia, M. 1996 Two- and -three dimensional simulations of aerosol transport and deposition in alveolar zone of human lung. J. Appl. Physiol. 80, 2889-2898.
5. Darquenne, C. 2001 A realistic two dimensional model of aerosol transport and deposition in the alveolar zone of the human lung. J. Aerosol Sci. 32, 1161-1174.
6. Federspiel, W. J. & Fredberg, J. J. 1988 Axial dispersion in respiratory bronchioles and alveolar ducts. J. Appl. Physiol. 64, 2614-2621.
7. Fredberg, J. J. 2000. Frozen objects: Small airways, big breaths, and asthma. J Allergy Clin Immunol. 106, 615-624.
8. Gradshtyn, I. S. & Ryzhik, I. M. 1984 Tables of Integrals, Series, and Products, 5th edn. Academic.
9. Haber, S., Butler, J. P., Brenner, H., Emanuel, I. & Tsuda, A. 2000 Shear flow over a self similar expanding pulmonary alveolus during rhythmical breathing. J. Fluid Mech. 405, 243-268.
10. Haber, H. & Tsuda, A. 2003 Gravitational deposition in a rhythmically expanding and contracting alveolus. J. Appl. Physiol. 95, 657-671.
11. Happel, J. & Brenner, H. 1983 Low Reynolds Number Hydrodynamics. Kluwer.
12. Henry, F. S., Butler, J. P. & Tsuda, A. 2002 Kinematically irreversible flow and aerosol transport in the pulmonary acinus: A departure from classical dispersive transport. J. Appl. Physiol. 92, 835-845.
13. Horner, M., Metcalfe, G., Wiggins, S. & Ottino, J. M. 2002 Transport enhancement mechanisms in open cavities. J. Fluid Mech. 452, 199-229.
14. Hydon, P. E. 1994 Resonant advection by oscillatory flow in a curved pipe. Physica D 76, 44-54.
15. Hydon, P. E. 1994 Resonant and chaotic advection in a curved pipe. Caos, Solitons Fractals 4, 941-954.
16. Karl, A., Henry, F. S. & Tsuda, A. 2004 Low Reynolds number viscous flow in an alveolated duct. Trans. ASME: J. Biomech. Engng 126, 13-19.
17. Lichtenberg, A. J. & Lieberman, M. A. 1992 Regular and Chaotic Dynamics. Springer.
18. Miki, H., Butler, J. P., Rogers, R. A., & Lehr, J. 1993 Geometric hysteresis in pulmonary surface to volume ratio during tidal breathing. J. Appl. Physiol. 75, 1630-1636.
19. Ottino, J. M., Leong, C. W., Rising, H. & Swanson, P. D. 1988 Morphological structures produced by mixing in chaotic flows. Nature 333, 419-425.
20. Ottino, J. M. 1989 The Kinematics of Mixing: Stretching, Chaos, and Transport. Cambridge University Press.
21. Pozrikidis, C. 1994 Shear flow over a plane wall with an axisymmetric cavity or a circular orifice of finite thickness. Phys. Fluids 6, 68-79.
22. Solomon, T. H., Weeks, E. R. & Swinney, H. L. 1994 Chaotic advection in a two-dimensional flow: Levy flights and anomalous diffusion. Physica D 76, 70-84.
23. Tabor, M. 1989 Chaos and Integrability in Nonlinear Dynamics. Wiley.
24. Tippe, A. & Tsuda, A. 2000 Recirculating flow in an expanding alveolar model: Experimental evidence of flow-induced mixing of aerosols in the pulmonary acinus. J. Aerosol Sci. 31, 979-986.
25. Tsuda, A., Butler, J. P. & Fredberg, J. J. 1994a Effects of alveolated duct structure on aerosol kinetics. I. diffusional deposition in the absence of gravity. J. Appl. Physiol. 76, 2497-2509.
26. Tsuda, A., Butler, J. P. & Fredberg, J. J. 1994b Effects of alveolated duct structure on aerosol kinetics. II. Gravitational sedimentation and inertial impaction. J. Appl. Physiol. 76, 2510-2516.
27. Tsuda, A., Federspiel, W. J., Grant, Jr, P. A. & Fredberg, J. J. 1991 Axial dispersion of inert species in alveolated channels. Chem. Engng Sci. 46, 1419-1426.
28. Tsuda, A., Henry, F. S. & Butler, J. P. 1995 Chaotic mixing of alveolated duct flow in rhythmically expanding pulmonary acinus. J. Appl. Physiol. 79, 1055-1063.
29. Tsuda, A., Rogers, R. A., Hydon, P. E. & Butler, J. P. 2002 Chaotic mixing deep in the lung. Proc. Natl Acad. Sci. USA 99, 10173-10178.
30. Weibel, E. R. 1963 Morphology of the lung. Academic.
31. Weibel, E. R. 1986 Functional morphology of lung parenchyma. In: Handbook of Physiology, The Respiratory System (ed. A. P. Fishman), sect. 3, vol. III, chap. 8, pp. 89-111. American Physiology Society, Bethesda, MD.