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Volumn 15, Issue 6, 2006, Pages 566-570

Dyslipidemia, inflammation and dialysis outcomes: What we know now

Author keywords

Dialysis; Dyslipidemia; Inflammation; Mortality; Outcome; Type 2 diabetes mellitus

Indexed keywords

ATORVASTATIN; C REACTIVE PROTEIN; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; ROSUVASTATIN;

EID: 33750213124     PISSN: 10624821     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.mnh.0000247501.41420.dd     Document Type: Review
Times cited : (9)

References (27)
  • 1
    • 0037137562 scopus 로고    scopus 로고
    • Effect of dialysis dose and membrane flux in maintenance hemodialysis
    • Hemodialysis (HEMO) Study Group
    • Eknoyan G, Beck GJ, Cheung AK, et al., Hemodialysis (HEMO) Study Group. Effect of dialysis dose and membrane flux in maintenance hemodialysis. N Engl J Med 2002; 347:2010-2019.
    • (2002) N Engl J Med , vol.347 , pp. 2010-2019
    • Eknoyan, G.1    Beck, G.J.2    Cheung, A.K.3
  • 2
    • 0036236303 scopus 로고    scopus 로고
    • Effects of increased peritoneal clearances on mortality rates in peritoneal dialysis: ADEMEX, a prospective, randomized, controlled trial
    • Mexican Nephrology Collaborative Study Group
    • Paniagua R, Amato D, Vonesh E, et al., Mexican Nephrology Collaborative Study Group. Effects of increased peritoneal clearances on mortality rates in peritoneal dialysis: ADEMEX, a prospective, randomized, controlled trial. J Am Soc Nephrol 2002; 13:1307-1320.
    • (2002) J Am Soc Nephrol , vol.13 , pp. 1307-1320
    • Paniagua, R.1    Amato, D.2    Vonesh, E.3
  • 3
    • 10744229858 scopus 로고    scopus 로고
    • Effect of fluvastatin on cardiac outcomes in renal transplant recipients: A multicentre, randomised, placebo-controlled trial
    • Assessment of LEscol in Renal Transplantation (ALERT) Study Investigators
    • Holdaas H, Fellstrom B, Jardine AG, et al., Assessment of LEscol in Renal Transplantation (ALERT) Study Investigators. Effect of fluvastatin on cardiac outcomes in renal transplant recipients: a multicentre, randomised, placebo-controlled trial. Lancet 2003; 361:2024-2031.
    • (2003) Lancet , vol.361 , pp. 2024-2031
    • Holdaas, H.1    Fellstrom, B.2    Jardine, A.G.3
  • 4
    • 22344458137 scopus 로고    scopus 로고
    • Atorvastatin in patients with type 2 diabetes mellitus undergoing hemodialysis
    • German Diabetes and Dialysis Study Investigators
    • Wanner C, Krane V, Marz W, et al., German Diabetes and Dialysis Study Investigators. Atorvastatin in patients with type 2 diabetes mellitus undergoing hemodialysis. N Engl J Med 2005; 353:238-248. This is the first large-scale, prospective, randomized, placebo-controlled trial testing the so far commonly accepted hypothesis that statin therapy in CKD patients is effective and safe. Against all expectations, it showed no significant reduction in the primary endpoint raising many questions about the type and character of cardiac and vascular disease in CKD patients and the associated causes of death. Simultaneously, it advises us to be cautious when extrapolating data from the general population to CKD patients and encourages us to get involved in clinical trials.
    • (2005) N Engl J Med , vol.353 , pp. 238-248
    • Wanner, C.1    Krane, V.2    Marz, W.3
  • 5
    • 0031007046 scopus 로고    scopus 로고
    • Atherogenic lipoprotein changes in the absence of hyperlipidemia in patients with chronic renal failure treated by hemodialysis
    • Shoji T, Ishizawa Y, Kawagishi T, et al. Atherogenic lipoprotein changes in the absence of hyperlipidemia in patients with chronic renal failure treated by hemodialysis. Atherosclerosis 1997; 131:229-236.
    • (1997) Atherosclerosis , vol.131 , pp. 229-236
    • Shoji, T.1    Ishizawa, Y.2    Kawagishi, T.3
  • 6
    • 0032895670 scopus 로고    scopus 로고
    • Apolipoprotein B-containing lipoproteins in renal failure: The relation to mode of dialysis
    • Attman P-O, Samuelsson O, Moberly J, et al. Apolipoprotein B-containing lipoproteins in renal failure: the relation to mode of dialysis. Kidney Int 1999; 55:1536-1542.
    • (1999) Kidney Int , vol.55 , pp. 1536-1542
    • Attman, P.-O.1    Samuelsson, O.2    Moberly, J.3
  • 7
    • 1642540483 scopus 로고    scopus 로고
    • Association between cholesterol level and mortality in dialysis patients: Role of inflammation and malnutrition
    • Liu Y, Coresh J, Eustace JA, et al. Association between cholesterol level and mortality in dialysis patients: role of inflammation and malnutrition. JAMA 2004; 291:451-459.
    • (2004) JAMA , vol.291 , pp. 451-459
    • Liu, Y.1    Coresh, J.2    Eustace, J.A.3
  • 8
    • 33744920293 scopus 로고    scopus 로고
    • Apolipoprotein B: A predictor of inflammatory status in postmenopausal overweight and obese women
    • Faraj M, Messier L, Bastard JP, et al. Apolipoprotein B: a predictor of inflammatory status in postmenopausal overweight and obese women. Diabetologia 2006; 49:1637-1646.
    • (2006) Diabetologia , vol.49 , pp. 1637-1646
    • Faraj, M.1    Messier, L.2    Bastard, J.P.3
  • 9
    • 4043134745 scopus 로고    scopus 로고
    • Rate of production of plasma and very-low-density lipoprotein (VLDL) apolipoprotein C-III is strongly related to the concentration and level of production of VLDL triglyceride in male subjects with different body weights and levels of insulin sensitivity
    • Cohn JS, Patterson BW, Uffelman KD, et al. Rate of production of plasma and very-low-density lipoprotein (VLDL) apolipoprotein C-III is strongly related to the concentration and level of production of VLDL triglyceride in male subjects with different body weights and levels of insulin sensitivity. J Clin Endocrinol Metab 2004; 89:3949-3955.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 3949-3955
    • Cohn, J.S.1    Patterson, B.W.2    Uffelman, K.D.3
  • 10
    • 0034680309 scopus 로고    scopus 로고
    • VLDL, apolipoproteins B, CIII, and E, and risk of recurrent coronary events in the Cholesterol and Recurrent Events (CARE) trial
    • Sacks FM, Alaupovic P, Moye LA, et al. VLDL, apolipoproteins B, CIII, and E, and risk of recurrent coronary events in the Cholesterol and Recurrent Events (CARE) trial. Circulation 2000; 102:1886-1892.
    • (2000) Circulation , vol.102 , pp. 1886-1892
    • Sacks, F.M.1    Alaupovic, P.2    Moye, L.A.3
  • 11
    • 33644866843 scopus 로고    scopus 로고
    • Apolipoprotein CIII in apolipoprotein B lipoproteins enhances the adhesion of human monocytic cells to endothelial cells
    • Kawakami A, Aikawa M, Libby P, et al. Apolipoprotein CIII in apolipoprotein B lipoproteins enhances the adhesion of human monocytic cells to endothelial cells. Circulation 2006; 113:691-700. By discovering that increased levels of apolipoprotein CIII cause enhanced adhesion of inflammatory cells to endothelial cells via PKC- and RhoA-mediated beta 1 integrin activation, the authors demonstrate a direct interrelation between the special type of dyslipidemia in chronic kidney disease and inflammation.
    • (2006) Circulation , vol.113 , pp. 691-700
    • Kawakami, A.1    Aikawa, M.2    Libby, P.3
  • 12
    • 33646458863 scopus 로고    scopus 로고
    • Mechanisms of dysregulation of low-density lipoprotein receptor expression in vascular smooth muscle cells by inflammatory cytokines
    • Ruan XZ, Moorhead JF, Tao JL, et al. Mechanisms of dysregulation of low-density lipoprotein receptor expression in vascular smooth muscle cells by inflammatory cytokines. Arterioscler Thromb Vasc Biol 2006; 26:1150-1155.
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , pp. 1150-1155
    • Ruan, X.Z.1    Moorhead, J.F.2    Tao, J.L.3
  • 13
    • 0042821576 scopus 로고    scopus 로고
    • Impact of dyslipidemia in end-stage renal disease
    • Prichard SS. Impact of dyslipidemia in end-stage renal disease. J Am Soc Nephrol 2003; 14:315-320.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 315-320
    • Prichard, S.S.1
  • 14
    • 0036233727 scopus 로고    scopus 로고
    • Hypocholesterolemia is a significant predictor of death in a cohort of chronic hemodialysis patients
    • Iseki K, Yamazato M, Tozawa M, Takishita S. Hypocholesterolemia is a significant predictor of death in a cohort of chronic hemodialysis patients. Kidney Int 2002; 61:1887-1893.
    • (2002) Kidney Int , vol.61 , pp. 1887-1893
    • Iseki, K.1    Yamazato, M.2    Tozawa, M.3    Takishita, S.4
  • 15
    • 21244498597 scopus 로고    scopus 로고
    • Clinical epidemiology of major nontraditional risk factors in peritoneal dialysis patients
    • Zoccali C, Enia G, Tripepi G, et al. Clinical epidemiology of major nontraditional risk factors in peritoneal dialysis patients. Perit Dial Int 2005; 25:84-87.
    • (2005) Perit Dial Int , vol.25 , pp. 84-87
    • Zoccali, C.1    Enia, G.2    Tripepi, G.3
  • 17
    • 33745494892 scopus 로고    scopus 로고
    • Association between C-reactive protein and clinical outcomes in peritoneal dialysis patients
    • Avram MM, Fein PA, Paluch MM, et al. Association between C-reactive protein and clinical outcomes in peritoneal dialysis patients. Adv Perit Dial 2005; 21:154-158.
    • (2005) Adv Perit Dial , vol.21 , pp. 154-158
    • Avram, M.M.1    Fein, P.A.2    Paluch, M.M.3
  • 18
    • 29244475380 scopus 로고    scopus 로고
    • Serum albumin, C-reactive protein, interleukin 6, and fetuin a as predictors of malnutrition, cardiovascular disease, and mortality in patients with ESRD
    • Honda H, Qureshi AR, Heimburger O, et al. Serum albumin, C-reactive protein, interleukin 6, and fetuin a as predictors of malnutrition, cardiovascular disease, and mortality in patients with ESRD. Am J Kidney Dis 2006; 47:139-148.
    • (2006) Am J Kidney Dis , vol.47 , pp. 139-148
    • Honda, H.1    Qureshi, A.R.2    Heimburger, O.3
  • 19
    • 0041342004 scopus 로고    scopus 로고
    • Cholesterol and the risk of renal dysfunction in apparently healthy men
    • Schaeffner ES, Kurth T, Curhan GC, et al. Cholesterol and the risk of renal dysfunction in apparently healthy men. J Am Soc Nephrol 2003; 14:2084-2091.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 2084-2091
    • Schaeffner, E.S.1    Kurth, T.2    Curhan, G.C.3
  • 20
    • 0037252331 scopus 로고    scopus 로고
    • C-reactive protein is associated with renal function abnormalities in a nondiabetic population
    • Stuveling EM, Hillege HL, Bakker SJ, et al. C-reactive protein is associated with renal function abnormalities in a nondiabetic population. Kidney Int 2003; 63:654-661.
    • (2003) Kidney Int , vol.63 , pp. 654-661
    • Stuveling, E.M.1    Hillege, H.L.2    Bakker, S.J.3
  • 21
    • 24944576760 scopus 로고    scopus 로고
    • Biomarkers of inflammation and progression of chronic kidney disease
    • Cholesterol and Recurrent Events (CARE) Trial Investigators
    • Tonelli M, Sacks F, Pfeffer M, et al., Cholesterol and Recurrent Events (CARE) Trial Investigators. Biomarkers of inflammation and progression of chronic kidney disease. Kidney Int 2005; 68:237-245. This post hoc subgroup analysis suggests that the loss of kidney function among subjects with chronic kidney disease and concomitant coronary disease may be mediated by inflammation.
    • (2005) Kidney Int , vol.68 , pp. 237-245
    • Tonelli, M.1    Sacks, F.2    Pfeffer, M.3
  • 22
    • 33746012877 scopus 로고    scopus 로고
    • Do inflammatory markers add predictive information of death beyond that provided by age and comorbidity in chronic renal failure patients?
    • Caravaca F, Martin MV, Barroso S, et al. Do inflammatory markers add predictive information of death beyond that provided by age and comorbidity in chronic renal failure patients? Nephrol Dial Transplant 2006; 21:1575-1581.
    • (2006) Nephrol Dial Transplant , vol.21 , pp. 1575-1581
    • Caravaca, F.1    Martin, M.V.2    Barroso, S.3
  • 23
    • 3042677716 scopus 로고    scopus 로고
    • C-reactive protein: Risk marker or mediator in atherothrombosis?
    • Jialal I, Devaraj S, Venugopal SK. C-reactive protein: risk marker or mediator in atherothrombosis? Hypertension 2004; 44:6-11.
    • (2004) Hypertension , vol.44 , pp. 6-11
    • Jialal, I.1    Devaraj, S.2    Venugopal, S.K.3
  • 24
    • 0037188605 scopus 로고    scopus 로고
    • Elevated C-reactive protein in patients with obstructive sleep apnea
    • Shamsuzzaman AS, Winnicki M, Lanfranchi P, et al. Elevated C-reactive protein in patients with obstructive sleep apnea. Circulation 2002; 105:2462-2464.
    • (2002) Circulation , vol.105 , pp. 2462-2464
    • Shamsuzzaman, A.S.1    Winnicki, M.2    Lanfranchi, P.3
  • 25
    • 0345492466 scopus 로고    scopus 로고
    • C-reactive protein and the risk of developing hypertension
    • Sesso HD, Buring JE, Rifai N, et al. C-reactive protein and the risk of developing hypertension. JAMA 2003; 290:2945-2951.
    • (2003) JAMA , vol.290 , pp. 2945-2951
    • Sesso, H.D.1    Buring, J.E.2    Rifai, N.3
  • 26
    • 4644272251 scopus 로고    scopus 로고
    • Randomized controlled trial on the efficacy and safety of atorvastatin in patients with type 2 diabetes on hemodialysis (4D study): Demographic and baseline characteristics
    • Deutsche Diabetes-Dialyse-Studie (4D) Study Group
    • Wanner C, Krane V, Marz W, et al., Deutsche Diabetes-Dialyse-Studie (4D) Study Group. Randomized controlled trial on the efficacy and safety of atorvastatin in patients with type 2 diabetes on hemodialysis (4D study): demographic and baseline characteristics. Kidney Blood Press Res 2004; 27:259-266.
    • (2004) Kidney Blood Press Res , vol.27 , pp. 259-266
    • Wanner, C.1    Krane, V.2    Marz, W.3
  • 27
    • 27544489356 scopus 로고    scopus 로고
    • Effect of rosuvastatin on outcomes in chronic haemodialysis patients: Design and rationale of the AURORA study
    • AURORA Study Group
    • Fellstrom B, Zannad F, Schmieder R, et al., AURORA Study Group. Effect of rosuvastatin on outcomes in chronic haemodialysis patients: design and rationale of the AURORA study. Curr Control Trials Cardiovasc Med 2005; 6:9.
    • (2005) Curr Control Trials Cardiovasc Med , vol.6 , pp. 9
    • Fellstrom, B.1    Zannad, F.2    Schmieder, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.