A pharmacological modulation of opiate withdrawal using an up-/down-regulation of the noradrenergic system in opiate-dependent rats

International Journal of Neuropsychopharmacology

Volumn 9, Issue 5, 2006, Pages 621-626

  Streel, Emmanuel ^a,c   Dan, Bernard ^a   Campanella, Salvatore ^b   Meyvaert, Alain ^a   Hanak, Catherine ^a   Pelc, Isy ^a   Verbanck, Paul ^a  

^a UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^b UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^c BRUGMANN UNIVERSITY HOSPITAL   (Belgium)

Author keywords

2 agonist antagonist; Clonidine; Opiate withdrawal; Rat; Yohimbine

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; ALPHA 2 ADRENERGIC RECEPTOR STIMULATING AGENT; CLONIDINE; MORPHINE; NALOXONE; OPIATE; YOHIMBINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; AUTONOMIC NERVOUS SYSTEM; BEHAVIOR; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG POTENTIATION; MALE; NONHUMAN; NORADRENERGIC SYSTEM; OPIATE ADDICTION; PRIORITY JOURNAL; RAT; STATISTICAL SIGNIFICANCE; WITHDRAWAL SYNDROME;

ADRENERGIC ALPHA-AGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANALYSIS OF VARIANCE; ANIMALS; BEHAVIOR, ANIMAL; CLONIDINE; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DOWN-REGULATION; DRUG INTERACTIONS; MALE; MORPHINE; MORPHINE DEPENDENCE; NARCOTICS; NOREPINEPHRINE; RATS; RATS, WISTAR; SUBSTANCE WITHDRAWAL SYNDROME; UP-REGULATION; YOHIMBINE;

EID: 33750204281     PISSN: 14611457     EISSN: 14695111     Source Type: Journal    
DOI: 10.1017/S1461145705006024     Document Type: Article

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