Transfusion-associated immunomodulation: Experimental facts and clinical reality - New perspectives

Transfusion Medicine and Hemotherapy

Volumn 33, Issue 4, 2006, Pages 324-329

  Nielsen, Hans Jørgen ^a  

^a HVIDOVRE HOSPITAL   (Denmark)

Author keywords

Blood transfusion; Cancer recurrence; Gene polymorphism; Immunomodulation; Infectious complications; Leukofiltration

Indexed keywords

BACTERIAL INFECTION; BLOOD AUTOTRANSFUSION; BLOOD COMPONENT THERAPY; BLOOD TRANSFUSION; CARCINOMA; CONFERENCE PAPER; GENETIC POLYMORPHISM; HEMODYNAMICS; IMMUNOMODULATION; POSTOPERATIVE INFECTION; SURVIVAL TIME; TISSUE OXYGENATION;

EID: 33750182022     PISSN: 16603796     EISSN: None     Source Type: Journal    
DOI: 10.1159/000092261     Document Type: Conference Paper

References (79)

1. Busch MP: Testing blood donors for HIV: current controversies. Immunol Invest 1995;24:147-54.
2. Tattevin P, Cremieux AC, Descamps D, Carbon C: Transfusion-related infectious mononucleosis. Scand J Infect Dis 2002;34:777-8.
3. Busch MP, Kleinman SH, Nemo GJ: Current and emerging infectious risks of blood transfusions. JAMA 2003;289:959-62.
4. Busch MP, Glynn SA, Stramer SL, Strong DM, Caglioti S, Wright DJ, Pappalardo B, Kleinman SH: A new strategy for estimating risks of transfusion-transmitted viral infections based on rates of detection of recently infected donors. Transfusion 2005;45:254-64.
5. Domen RE: An overview of immune hemolytic anemias. Cleve Clin J Med 1998;65:89-99.
6. Bux J: Transfusion-related acute lung injury (TRALI): a serious adverse event of blood transfusion. Vox Sang 2005;89:1-10.
7. Nusbacher J: Blood transfusion is mononuclear cell transplantation. Transfusion 1994;34:1002-6.
8. Izbicki G, Rudensky B, Na'amad M, Hershko C, Huerta M, Hersch M: Transfusion-related leukocytosis in critically ill patients. Crit Care Med 2004;32:439-42.
9. Olszewski WL, Interewicz B, Maksymowicz M, Stanislawska J: Transplantation of organs is transplantations of donor DNA: fate of DNA disseminated in recipient. Transpl Int 2005;18:412-8.
10. Bouwman LH, Roos A, Terpstra OT, de Knijff P, van Hoek B, Verspaget HW, Berger SP, Daha MR, Frolich M, van der Slik AR, Doxiadis Jr, Roep BO, Schaapherder AF: Mannose binding lectin gene polymorphisms confer a major risk for severe infections after liver transplantation. Gastroenterology 2005;129:408-14.
11. Lee TH, Paglieroni T, Ohto H, Holland PV, Busch MP: Survival of donor leukocyte subpopulations in immunocompetent transfusion recipients: frequent long-term microchimerism in severe trauma patients. Blood 1999;93:3127-39.
12. Utter GH, Owings JT, Lee TH, Paglieroni TG, Reed WF, Gosselin RC, Holland PV, Busch MP: Blood transfusion is associated with donor leukocyte microchimerism in trauma patients. J Trauma 2004;57:702-8.
13. Busch MP, Lee TH: Role of donor leukocytes and leukodepletion in transfusion-associated viral infections; in Sweeney J, Heaton WA (eds): Clinical Benefits of Leukodepletet Blood Products. Austin, Landers, 1995, pp 97-102.
14. Mosier DE, Baird SM, Kirven MB, Gulizia RJ, Wilson DB, Kunayashi R, Picchio G, Garnier JL, Sullivan JL, Kipps TJ: EBV-associated B-cell lymphomas following transfer of severe human peripheral blood lymphocytes to mice with severe combined immune deficiency. Curr Top Microbiol Immunol 1990;166:317-23.
15. Di Bisceglie AM, Simpson LH, Lotze MT, Hoofnagle JH: Development of hepatocellular carcinoma among patients with chronic liver disease due to hepatitis C viral infection. J Clin Gastroenterol 1994;19:222-6.
16. Blomberg J, Möller T, Olsson H, Anderson H, Jonsson M: Cancer morbidity in blood recipients - results of a cohort study. Eur J Cancer 1993;29A:2101-5.
17. Memon A, Doll R: A search for unknown bloodborne oncogenic viruses. Int J Cancer 1994;58:366-8.
18. Brandt L, Brandt J, Olsson H, Anderson H, Möller T: Blood transfusion as a risk factor for non-Hodgkin lymphoma. Br J Cancer 1996;73:1148-51.
19. Cerhan JR, Wallace RB, Folsom AR, Potter JD, Sellers TA, Zheng W, Lutz CT: Medical history risk factors for non-Hodgkin's lymphoma in older women. J Natl Cancer Inst 1997;89:314-8.
20. Adami J, Nyren O, Bergström R, Ekbom A, McLaughlin JK, Hogman C, Fraumeri JF, Glimelius B: Blood transfusion and non-Hodgkin lymphoma: lack of association. Ann Intern Med 1997;127:365-71.
21. Vamvakas EC: Allogeneic blood transfusion as a risk factor for the subsequent development of non-Hodgkin's lymphoma. Transfus Med Rev 2000;14:258-68.
22. Cerhan JR, Wallace RB, Dick F, Kemp J, Parker AS, Zheng W, Sellers TA, Folsom AR: Blood transfusions and risk of non-Hodgkin's lymphoma subtypes and chronic lymphocytic leukaemia. Cancer Epidemiol Biomarkers Prev 2001;10:361-8.
23. Anderson H, Brandt L, Ericson A, Olsson H, Möller T: Blood transfusion at delivery and risk of subsequent malignant lymphoma in the mother. Vox Sang 1998;75:145-8.
24. Skanberg J, Frisk B: Blood transfusion does not influence the development of malignant tumours. Eur J Surg 1999;165:528-34.
25. Blajchman MA: Transfusion immunomodulation or TRIM: what does it mean clinically? Hematology 2005;10(suppl 1):208-14.
26. Mynster T: Blood transfusion-induced immunomodulation - is storage time important? Thesis. Dan Med Bull 2003;50:368-84.
27. Nielsen HJ: Clinical impact of bioactive substances in blood components: Implications for leukocyte filtration. Infusionther Transfusionmed 1998;25:296-304.
28. Nielsen HJ: The effect of histamine type-2 receptor antagonists on posttraumatic immune competence. Thesis. Dan Med Bull 1995;42:162-74.
29. Carson JL, Altman DG, Duff A, Noveck H, Weinstein MP, Sonnenberg FA, Hudson JI, Provenzano G: Risk of bacterial infection associated with allogeneic blood transfusion among patients undergoing hip fracture repair. Transfusion 1999;39:694-700.
30. Chang H, Hall GA, Geerts WH, Greenwood C, McLeod RS, Sher GD: Allogeneic red blood cell transfusion is an independent risk factor for the development of postoperative bacterial infection. Vox Sang 2000;78:13-8.
31. Taylor RW, Manganaro L, O'Brian J, Trottier SJ, Parkar N, Veremakis C: Impact of allogeneic packed red blood cell transfusion on nosocomial infection rates in the critically ill patient. Crit Care Med 2002;30:2249-54.
32. Claridge JA, Sawyer RG, Schulman Am, McLemore EC, Young JS: Blood transfusions correlate with infections in trauma patients in a dose-dependent manner. Am Surg 2002;68:566-72.
33. Malone DL, Dunne J, Tracy JK, Putman AT, Scalea TM, Napolitano LM: Blood transfusion, independent of shock severity, is associated with worse outcome in trauma. J Trauma 2003;54:898-907.
34. Hill GE, Frawley WH, Griffith KE, Forester JE, Minei JP: Allogeneic blood transfusion increases the risk of postoperative bacterial infection: A meta-analysis. J Trauma 2003;54:908-14.
35. Hammer JH, Basse L, Werther K, Svendsen MN, Brünner N, Christensen IJ, Nielsen HJ. Impact of elective resection on plasma TIMP-1 levels in patients with colorectal cancer. Colorectal Dis 2006;8:168-72.
36. Amato AC, Pescatori M: Effect of perioperative blood transfusions on recurrence of colorectal cancer. Meta-analysis stratified on risk factors. Dis Colon Rectum 1998;41:570-85.
37. Oda S, Zhao Y, Maehara Y: Microsatellite instability in gastrointestinal cancers: abrief update. Surg Today 2005;35:1005-15.
38. Pantel K, Woelfle U: Detection and molecular characterisation of disseminated tumour cells: implications for anti-cancer therapy. Biochim Biophys Acta 2005;1756:53-64.
39. McArdle CS, Hole D: Impact of variability among surgeons on postoperative morbidity and mortality and ultimate survival. BMJ 1991;302:1501-5.
40. McArdle CS, Hole DJ: Emergency presentation of colorectal cancer is associated with poor 5-year survival. Br J Surg 2004;91:605-9.
41. Mynster T, Christensen IJ, Moesgaard F, Nielsen HJ: Effects of the combination of blood transfusion and postoperative infectious complications on prognosis after surgery for colorectal cancer. Br J Surg 2000;87:1553-62.
42. Grandis JR, Snyderman CH, Johnsen JT, Yu VL, D'Amico F: Postoperative wound infection. A poor prognostic sign for patients with head and neck cancer. Cancer 1992;70:2166-70.
43. Sturgis EM, Congdon DJ, Mather FJ, Miller RH: Perioperative transfusion, postoperative infection, and recurrence of head and neck cancer. South Med J 1997;90:1217-24.
44. Kressner U, Graf W, Mehteme H, Påhlman L, Glimelius B: Septic complications and prognosis after surgery for rectal cancer. Dis Colon Rectum 2002;45:316-21.
45. Innerhofer P, Klingler A, Klimmer C, Fries D, Nussbaumer W: Risk for postoperative infection after blood transfusion of white blood cell-filtered allogeneic or autologous blood components in orthopedic patients undergoing primary arthroplasty. Transfusion 2005;45:103-10.
46. Busch OR, Hop WCJ, Hoynck van Papendrecht MAW, Marquet RL, Jeekel J: Blood transfusion and prognosis in colorectal cancer. N Engl J Med 1993;328:1372-6.
47. Nielsen HJ, Reimert CM, Pedersen AN, Brünner N, Edvardsen L, Dybkjaer E, Kehlet H, Skov PS: Time-dependent, spontaneous release of white cell-and platelet-derived bioactive substances from stored human blood. Transfusion 1996;36:900-5.
48. Nielsen HJ, Reimert C, Pedersen AN, Dybkjaer E, Brünner N, Alsbjorn B, Skov PS: Leucocyte-derived bioactive substances in fresh frozen plasma. Br J Anaesth 1997;78:548-52.
49. Edvardsen L, Taaning E, Drachmann O, Mynster T, Nielsen HJ: Accumulation of bioactive substances during storage of various platelet components. Am J Hematol 2001;67:157-62.
50. Nielsen HJ, Werther K, Mynster T, Brünner N: Soluble vascular endothelial growth factor in various blood transfusion components. Transfusion 1999;39:1078-83.
51. Biedler AE, Schneider SO, Seyfert U, Reusing H, Grenner S, Gimdt M, Bauer I, Bauer M: Impact of alloantigens and storage-associated factors on stimulated cytokine response in an in vitro model of blood transfusion. Anesthesiology 2002;97:1002-9.
52. Patel HB, Nasir FA, Nash GF, Scully MF, Kakkar AK: Enhanced angiogenesis following allogeneic blood transfusion. Clin Lab Haematol 2004;26:129-35.
53. Purdy FR, Tweeddale MA, Merrick PM: Association of mortality with age of blood transfused in septic ICU patients. Can J Anaesth 1997;44:1256-61.
54. Vamvakas EC, Carven JH: Transfusion and postoperative pneumonia in coronary artery bypass graft surgery: effect of the length of storage of transfused red cells. Transfusion 1999;39:701-10.
55. Zallen G, Offner PJ, Moore EE, Blackwell J, Ciesla DJ, Gabriel J, Denney C, Silliman CC: Age of transfused blood is an independent risk factor for postinjury multiple organ failure. Am J Surg 1999;178:570-2.
56. Mynster T, Nielsen HJ: The impact of storage time of transfused blood on postoperative infectious complications in rectal cancer surgery. Scand J Gastroenterol 2000;35:212-7.
57. Offner PJ, Moore EE, Biffl WL, Johnson JL, Silliman CC: Increased rate of infection associated with transfusion of old blood after severe injury. Arch Surg 2002;137:711-7.
58. Keller ME, Jean R, LaMorte WW, Millham F, Hirsch E: Effects of age of transfused blood on length of stay in trauma patients: a preliminary report. J Trauma 2002;53:1023-5.
59. Nielsen HJ, Hammer JH, Krarup AL, Nielsen LM, Reimert CM, Pedersen AN, Dybkjær E, Partoft S, Alsbjørn B: Prestorage leucocyte filtration may reduce leucocyte-derived bioactive substance accumulation in patients operated for burn trauma. Burns 1999;25:162-170.
60. Hebert PC, Fergusson D, Blajchman MA, Wells GA, Kmetic A, Coyle D, Heddle N, Germain M, Goldman M, Toye B, Schweitzer I, van Wakraven C, Devine D, Sher GD: Clinical outcomes following institution of the Canadian universal leukoreduction program for red blood cell transfusions. JAMA 2003;289:1941-9.
61. van Hilten JA, van de Watering LMG, van Bockel JH, van de Velde CJH, Kivit J, Brand R, van den Hout WB, Geelkerken RH, Roumen RMH, Wesselink RMJ, Koopman-van Gemert AW, Koning J, Brand A: Effects of transfusion with red cells filtered to remove leucocytes: randomised controlled trial in patients undergoing major surgery. BMJ 2004;328:1281-9.
62. Fergusson D, Khanna MP, Tinmouth A, Hebert PC: Transfusion of leukoreduced red blood cells may decrease postoperative infections: two meta-analyses of randomized controlled trials. Can J Anaesth 2004;51:417-24.
63. Houbiers JG, Brand A, van de Watering LM, Hermans J, Verwey PJ, Bijnen AB, Pahlplatz P, Eeftinck Schattenkerk M, Wobbes T, de Vries JE: Randomised controlled trial comparing transfusion of leucocyte-depleted or buffy-coat-depleted blood in surgery for colorectal cancer. Lancet 1994;344:573-8.
64. van de Watering LM, Brand A, Houbiers JG, Klein Kranenbarg WM, Hermans J, van de Velde C: Perioperative blood transfusions, with or without allogeneic leucocytes, relate to survival, not to cancer recurrence. Br J Surg 2001;88:267-72.
65. Jensen LS, Puho E, Pedersen L, Mortensen FV, Sørensen HT: Long-term survival after colorectal surgery associated with buffy-coat-poor and leukocyte-depleted blood transfusion: a follow-up study. Lancet 2005;365:681-2.
66. Hammer JH, Mynster T, Reimert CM, Brünner N, Nielsen HJ: Reduction of bioactive substances in donor blood. Prestorage versus bedside leucofiltration. Eur J Haematol 1999;63:29-34.
67. Mynster T, Hammer JH, Nielsen HJ: Prestorage and bedside leucofiltration of whole blood modulates storage time dependent suppression of in vitro TNF release. Br J Haematol 1999;106:248-51.
68. Nielsen HJ, Werther K, Mynster T, Svendsen MN, Rosendahl S, Elley T, Skov F: Bacteria-induced release of white cell- and platelet-derived vascular endothelial growth factor in vitro. Vox Sang 2001;80:170-8.
69. Hammer JH, Mynster T, Reimert CM, Brünner N, Skov F, Nielsen HJ: Bacteria-induced release of white cell- and platelet-derived bioactive substances in vitro. Int J Gastrointest Cancer 2003;31:165-79.
70. Bordin JO, Bardossy L, Blajchman MA: Growth enhancement of established tumors by allogeneic blood transfusion in experimental animals and its amelioration by leukodepletion. Blood 1994;84:344-8.
71. Sirchia G, Giovanetti AM, McClelland B, Fracchia GN: Safe and Good Use of Blood in Surgery (SANGUIS). Use of Blood and Artificial Colloids in 43 European Hospitals. Strasbourg, Council of Europe Publishing 1994, pp 1-235.
72. Carson JL, Duff A, Berlin JA, Lawrence VA, Poses RM, Huber EC, O'Hara DA, Noveck H, Strom BL: Perioperative blood transfusion and postoperative mortality. JAMA 1998;279:199-205.
73. Hebert PC, Wells G, Blajchman MA, Marshall J, Martin C, Pagliarello G, Tweeddale M, Schweitzer I, Yetisir E: A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. N Engl J Med 1999;340:409-17.
74. Vincent LJ, Baron JF, Reinhart K, Gattinoni L, Thijs L, Webb A, Meier-Hellmann A, Nollet G, Pers-Bota D: Anemia and blood transfusion in critically ill patients. JAMA 2002;288:1499-507.
75. Poon RT, FAN ST, Lo CM, Liu CL, Yuen WK, Yeung C, Wu J: Improving perioperative outcome expands the role of hepatotectomy in management of benign and malignant hepatobiliary diseases: analysis of 1222 consecutive patients from a prospective data set. Ann Surg 2004;240:698-708.
76. Ytting H, Jensenius JC, Thiel S, Christensen IJ, Nielsen HJ: Increased activity of the MBL pathway in patients with colorectal cancer. Scand J Gastroenterol 2004;39:674-9.
77. Ytting H, Christensen IJ, Jensenius JC, Thiel S, Nielsen HJ: Preoperative mannan-binding lectin pathway and prognosis in colorectal cancer. Cancer Immunol Immunother 2005:54:265-72.
78. Gomi K, Tokue Y, Kobayashi T, Takahashi H, Watanabe A, Fujita T, Nukiwa T: Mannose-binding lectin gene polymorphism is a modulating factor in repeated respiratory infections. Chest 2004;126:95-9.
79. Thiel S, Frederiksen PD, Jensenius JC: Clinical manifestations of mannan-binding lectin deficiency. Mol Immunol 2006;43:86-96.