Interleukin-8 and soluble intercellular adhesion molecule 1 during acute respiratory distress syndrome and in response to prolonged methylprednisolone treatment

Minerva Pneumologica

Volumn 45, Issue 2, 2006, Pages 93-103

  Sinclair, S E ^a   Golden, E B ^a   Carratu, P ^a   John, B E ^a   Umberger, R A ^a   Meduri, G U ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

Acute respiratory distress syndrome; Adhesion, molecules; Interleutins

Indexed keywords

INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 8; METHYLPREDNISOLONE; PLACEBO;

ADULT; ADULT RESPIRATORY DISTRESS SYNDROME; ARTICLE; BLOOD ANALYSIS; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DISEASE COURSE; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; FEMALE; HUMAN; LUNG LAVAGE; MALE; NEUTROPHILIA; RANDOMIZED CONTROLLED TRIAL; SCORING SYSTEM; SURVIVAL; TREATMENT DURATION; TREATMENT RESPONSE;

EID: 33750176031     PISSN: 00264954     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (60)

1. Downey GP, Dong Q, Kruger J, Dedhar S, Cherapanov V. Regulation of neutrophil activation in acute lung injury. Chest 1999;116(1 Suppl):46S-54S.
2. Chollet-Martin S, Montravers P, Gibert C, Elbim C, Desmonts JM, Fagon JY, Gougerot-Pocidalo MA. Relationships between polymorphonuclear neutrophils and cytokines in patients with adult respiratory distress syndrome. Ann N Y Acad Sci 1994;725: 354-66.
3. Martin TR, Pistorese BP, Hudson LD, Maunder RJ. The function of lung and blood neutrophils in patients with the adult respiratory distress syndrome. Implications for the pathogenesis of lung infections. Am Rev Respir Dis 1991;144:254-62.
4. Weiland JE, Davis WB, Holter JF, Mohammed JR, Dorinsky PM, Gadek JE. Lung neutrophils in the adult respiratory distress syndrome. Clinical and pathophysiologic significance. Am Rev Respir Dis 1986;133: 218-25.
5. Gunther K, Baughman RP, Rashkin M, Pattishall E. Bronchoalveolar lavage results in patients with sepsis-induced adult respiratory distress syndrome: evaluation of mortality and inflammatory response. Amer Rev Respir Dis 1993;147:A346.
6. Steinberg KP, Milberg JA, Martin TR, Maunder RJ, Cockrill BA, Hudson LD. Evolution of bronchoalveolar cell populations in the adult respiratory distress syndrome. Am J Respir Crit Care Med 1994;150: 113-22.
7. Strieter RM, Kunkel SL, Keane MP, Standiford TJ. Chemokines in lung injury: Thomas A. Neff Lecture. Chest 1999;116(1 Suppl):103S-110S.
8. Folkesson HG, Matthay MA, Hebert CA, Broaddus VC. Acid aspiration-induced lung injury in rabbits is mediated by interleukin-8-dependent mechanisms. J Clin Invest 1995;96:107-16.
9. Mukaida N. Pathophysiological roles of interleukin-8/CXCL8 in pulmonary diseases. Am J Physiol Lung Cell Mol Physiol 2003;284:L566-577.
10. Donnelly SC, Strieter RM, Kunkel SL, Walz A, Robertson CR, Carter DC et al. Interleukin-8 and development of adult respiratory distress syndrome in at-risk patient groups. Lancet 1993;341:643-7.
11. Collins T. Adhesion molecules in leukocyte emigration. Scientific American 1995;2:28-37.
12. Kasper M, Koslowski R, Luther T, Schuh D, Muller M, Wenzel KW. Immunohistochemical evidence for loss of ICAM-1 by alveolar epithelial cells in pulmonary fibrosis. Histochem Cell Biol 1995;104:397-405.
13. Korthuis RJ, Anderson DC, Granger DN. Role of neutrophil-endothelial cell adhesion in inflammatory disorders. J Crit Care 1994;9:47-71.
14. Cronstein BN, Weissmann G. The adhesion molecules of inflammation. Arthritis Rheum 1993;36:147-57.
15. Conner ER, Ware LB, Modin G, Matthay MA. Elevated pulmonary edema fluid concentrations of soluble intercellular adhesion molecule-1 in patients with acute lung injury: biological and clinical significance. Chest 1999;116(1 Suppl):83S-84S.
16. Grau GE, Mili N, Lou JN, Morel DR, Ricou B, Lucas R et al. Phenotypic and functional analysis of pulmonary microvascular endothelial cells from patients with acute respiratory distress syndrome. Lab Invest 1996;74: 761-70.
17. Moss M, Gillespie MK, Ackerson L, Moore FA, Moore EE, Parsons PE. Endothelial cell activity varies in patients at risk for the adult respiratory distress syndrome. Crit Care Med 1996;24:1782-6.
18. Nagase T, Ohga E, Sudo E, Katayama H, Uejima Y, Matsuse T et al. Intercellular adhesion molecule-1 mediates acid aspiration-induced lung injury. Am J Respir Crit Care Med 1996;154(2 Pt 1):504-10.
19. Gando S, Kameue T, Matsuda N, Sawamura A, Hayakawa M, Kato H. Systemic inflammation and disseminated intravascular coagulation in early stage of ALI and ARDS: role of neutrophil and endothelial activation. Inflammation 2004;28:237-44.
20. Gando S, Kameue T, Matsuda N, Hayakawa M, Ishitani T, Morimoto Y et al. Combined activation of coagulation and inflammation has an important role in multiple organ dysfunction and poor outcome after severe trauma. Thromb Haemost 2002;88:943-9.
21. Amat M, Barcons M, Mancebo J, Mateo J, Oliver A, Mayoral JF et al. Evolution of leukotriene B4, peptide leukotrienes, and interleukin-8 plasma concentrations in patients at risk of acute respiratory distress syndrome and with acute respiratory distress syndrome: mortality prognostic study. Crit Care Med 2000;28: 57-62.
22. Chollet-Martin S, Jourdain B, Gibert C, Elbim C, Chastre J, Gougerot-Pocidalo MA. Interactions between neutrophils and cytokines in blood and alveolar spaces during ARDS. Am J Respir Crit Care Med 1996;154(3 Pt 1):594-601.
23. Chollet-Martin S, Montravers P, Gibert C, Elbim C, Desmonts JM, Fagon JY et al. High levels of interleukin-8 in the blood and alveolar spaces of patients with pneumonia and adult respiratory distress syndrome. Infect Immun 1993;61:4553-4559.
24. Groeneveld AB, Kindt I, Raijmakers PG, Hack CE, Thijs LG. Systemic coagulation and fibrinolysis in patients with or at risk for the adult respiratory distress syndrome. Thromb Haemost 1997;78:1444-9.
25. Groeneveld AB, Raijmakers PG, Hack CE, Thijs LG. Interleukin 8-related neutrophil elastase and the severity of the adult respiratory distress syndrome. Cytokine 1995;7:746-52.
26. Hack CE, Hart M, van Schijndel RJ, Eerenberg AJ, Nuijens JH, Thijs LG et al. Interleukin-8 in sepsis: relation to shock and inflammatory mediators. Infect Immun 1992;60:2835-42.
27. Ikuta N, Taniguchi H, Kondoh Y, Takagi K, Hayakawa T. Sustained high levels of circulatory interleukin-8 are associated with a poor outcome in patients with adult respiratory distress syndrome. Intern Med 1996;3: 855-60.
28. Meduri GU, Headley S, Kohler G, Stentz F, Tolley E, Umberger R et al. Persistent elevation of inflammatory cytokines predicts a poor outcome in ARDS. Plasma IL-1 beta and IL-6 levels are consistent and efficient predictors of outcome over time. Chest 1995;107: 1062-73.
29. Nakae H, Endo S, Inada K, Kasai T, Yoshida M. Significance of alpha-tocopherol and interleukin 8 in septic adult respiratory distress syndrome. Res Commun Chem Pathol Pharmacol 1994;84:197-202.
30. Baughman RP, Gunther KL, Rashkin MC, Keeton DA, Pattishall EN. Changes in the inflammatory response of the lung during acute respiratory distress syndrome: prognostic indicators. Am J Respir Crit Care Med 1996;154:76-81.
31. Goodman RB, Strieter RM, Martin DP, Steinberg KP, Milberg JA, Maunder RJ et al. Inflammatory cytokines in patients with persistence of the acute respiratory distress syndrome. Am J Respir Crit Care Med 1996;154(3 Pt 1):602-11.
32. Gunther K, Baughman RP, Pattishall E, Whitsell J. Evaluation of intrapulmonary interleukin-8 in patients with sepsis-induced adult respiratory distres s syndrome. Am J Respir Crit Care Med 1994;149:A427.
33. Jorens PG, Van Damme J, De Backer W, Bossaert L, De Jongh RF, Herman AG et al. Interleukin 8 (IL-8) in the bronchoalveolar lavage fluid from patients with the adult respiratory distress syndrome (ARDS) and patients at risk for ARDS. Cytokine 1992;4:592-7.
34. Kiehl MG, Ostermann H, Thomas M, Muller C, Cassens U, Kienast J. Inflammatory mediators in bronchoalveolar lavage fluid and plasma in leukocytopenic patients with septic shock-induced acute respiratory distress syndrome. Crit Care Med 1998;26:1194-9.
35. Meduri GU, Kohler G, Headley S, Tolley E, Stentz F, Postlethwaite A. Inflammatory cytokines in the BAL of patients with ARDS. Persistent elevation over time predicts poor outcome. Chest 1995;108:1303-14.
36. Miller EJ, Cohen AB, Nagao S, Griffith D, Maunder RJ, Martin TR et al. Elevated levels of NAP-1/interleukin-8 are present in the airspaces of patients with the adult respiratory distress syndrome and are associated with increased mortality. Am Rev Respir Dis 1992;146: 427-32.
37. Villard J, Dayer-Pastore F, Hamacher J, Aubert JD, Schlegel-Haueter S, Nicod LP. GRO alpha and interleukin-8 in Pneumocystis carinii or bacterial pneumonia and adult respiratory distress syndrome. Am J Respir Crit Care Med 1995;152(5 Pt 1):1549-54.
38. Meduri GU, Headley S, Tolley E, Shelby M, Stentz F, Postlethwaite A. Plasma and BAL cytokine response to corticosteroid rescue treatment in late ARDS. Chest 1995;108:1315-25.
39. Bernard GR, Artigas A, Brigham KL, Carlet J, Falke K, Hudson L et al. The American-European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination. Am J Respir Crit Care Med 1994;149(3 Pt 1):818-824.
40. Murray JF, Matthay MA, Luce JM, Flick MR. An expanded definition of the adult respiratory distress syndrome. Am Rev Respir Dis 1988;138:720-3.
41. Slutsky AS. Mechanical ventilation. American College of Chest Physicians' Consensus Conference. Chest 1993;104:1833-59.
42. Meduri GU, Headley S, Golden E, Carson S, Umberger R, Kelso T et al. Effect of prolonged methylprednisolone therapy in unresolving acute respiratory distress syndrome. A randomized controlled trial. JAMA 1998;280: 159-65.
43. Meduri GU, Tolley EA, Chinn A, Stentz F, Postlethwaite A. Procollagen types I and III aminoterminal propeptide levels during acute respiratory distress syndrome and in response to methylprednisolone treatment. Am J Respir Crit Care Med 1998;158(5 Pt 1):1432-41.
44. Meduri GU, Chastre J. The standardization of bronchoscopic techniques for ventilator- associated pneumonia. Chest 1992;102(5 Suppl 1):557S-564S.
45. Meduri GU, Beals DH, Maijub AG, Baselski V. Protected bronchoalveolar lavage. A new bronchoscopic technique to retrieve uncontaminated distal airway secretions. Am Rev Respir Dis 1991;143(4 Pt 1):855-64.
46. Meduri GU, Tolley EA, Chrousos GP, Stentz F. Prolonged methylprednisolone treatment suppresses systemic inflammation in patients with unresolving acute respiratory distress syndrome. Evidence for inadequate endogenous glucocorticoid secretion and inflammation-induced immune cell resistance to glucocorticoids. Am J Respir Crit Care Med 2002;165: 983-91.
47. Doerschuk CM, Mizgerd JP, Kubo H, Qin L, Kumasaka T. Adhesion molecules and cellular biomechanical changes in acute lung injury: Giles F. Filley Lecture. Chest 1999;116(1 Suppl):37S-43S.
48. Groeneveld ABJ. A central role of interleukin-8 in the pathogenesis of ARDS. In: 1998 Yearbook of Intensive Care and Emergency Medicine. Edited by Vincent J-L. New York: Springer-Verlag, 1998.p.65-74.
49. McKay LI, Cidlowski JA. Molecular control of immune/inflammatory responses: interactions between nuclear factor-kappa B and steroid receptor-signaling pathways. Endocr Rev 1999;20:435-59.
50. Baeuerle PA, Baltimore D. NF-kappa B: ten years after. Cell 1996;87:13-20.
51. Stentz F, Tolley EA, Headley AS, Chrousos GP, Meduri GU. Mechanisms of NF-ÎB and glucocorticoid receptor (GR·) in activation and regulation of systemic inflammation (SI) in ARDS (Abstract). Am J Respir Crit Care Med 2001;163:A450.
52. Bamberger CM, Schulte HM, Chrousos GP. Molecular determinants of glucocorticoid receptor function and tissue sensitivity to glucocorticoids. Endocr Rev 1996;17: 245-61.
53. Didonato JA, Saatcioglu F, Karin M. Molecular mechanisms of immunosuppression and anti-inflammatory activities by glucocorticoids. Am J Respir Crit Care Med 1996;154(2Pt 2):S11-15.
54. Mukaida N, Monta M, Ishikawa Y, Rice N, Okamoto S, Kasahara T et al. Novel mechanism of glucocorticoid-mediated gene repression. Nuclear factor-kappa B is target for glucocorticoid-mediated interleukin 8 gene repression. J Biol Chem 1994;269:13289-95.
55. Kwon OJ, Au BT, Collins PD, Baraniuk JN, Adcock IM, Chung KF et al. Inhibition of interleukin-8 expression by dexamethasone in human cultured airway epithelial cells. Immunology 1994;81:389-94.
56. Tobler A, Meier R, Seitz M, Dewald B, Baggiolini M, Fey MF. Glucocorticoids downregulate gene expression of GM-CSF, NAP-1/IL-8, and IL-6, but not of M-CSF in human fibroblasts. Blood 1992;79:45-51.
57. Cronstein BN, Kimmel SC, Levin RI, Martiniuk F, Weissmann G. A mechanism for the antiinflammatory effects of corticosteroids: the glucocorticoid receptor regulates leukocyte adhesion to endothelial cells and expression of endothelial-leukocyte adhesion molecule 1 and intercellular adhesion molecule 1. Proc Natl Acad Sci USA 1992;89:9991-5.
58. van de Stolpe A, Caldenhoven E, Raaijmakers JA, van der Saag PT, Koenderman L. Glucocorticoid-mediated repression of intercellular adhesion molecule-1 expression in human monocytic and bronchial epithelial cell lines. Am J Respir Cell Mol Biol 1993;8:340-7.
59. Wang JH, Devalia JL, Sapsford RJ, Davies RJ. Effect of corticosteroids on release of RANTES and sICAM-1 from cultured human bronchial epithelial cells, induced by TNF-alpha. Eur Respir J 1997;10:834-40.
60. Warshawski FJ, Sibbald WJ, Driedger AA, Cheung H. Abnormal neutrophil-pulmonary interaction in the adult respiratory distress syndrome. Qualitative and quantitative assessment of pulmonary neutrophil kinetics in humans with in vivo 111indium neutrophil scintigraphy. Am Rev Respir Dis 1986;133:797-804.