Blood pressure regulation by CCR genes

Clinical and Experimental Hypertension

Volumn 28, Issue 7, 2006, Pages 611-618

  Mettimano, Marco ^a   Specchia, Maria Lucia ^a   La Torre, Giuseppe ^a   Bruno, Antonio ^a   Ricciardi, Gualtiero ^a   Savi, Luigi ^a   Romano Spica, Vincenzo ^b  

^a CATHOLIC UNIVERSITY   (Italy)

^b UNIVERSITY OF ROME FORO ITALICO   (Italy)

Author keywords

ABPM; Chemokine; Hypertension

Indexed keywords

CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CCR5;

ADULT; ALLELE; AMBULATORY MONITORING; ARTICLE; BLOOD PRESSURE MONITORING; BLOOD PRESSURE REGULATION; BLOOD PRESSURE VARIABILITY; CCR2 GENE; CCR5 GENE; CIRCADIAN RHYTHM; DEVICE; DIASTOLIC BLOOD PRESSURE; DNA POLYMORPHISM; ESSENTIAL HYPERTENSION; FEMALE; GENE; GENE CONTROL; GENE FREQUENCY; GENETIC ASSOCIATION; GENOTYPE; HUMAN; IMMUNE SYSTEM; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MALE; MOLECULAR BIOLOGY; MONITOR; OUTPATIENT; POLYMERASE CHAIN REACTION; SYSTOLIC BLOOD PRESSURE;

ADULT; BLOOD PRESSURE; BLOOD PRESSURE MONITORING, AMBULATORY; CIRCADIAN RHYTHM; FEMALE; GENE EXPRESSION REGULATION; GENE FREQUENCY; GENOTYPE; HUMANS; HYPERTENSION; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; RECEPTORS, CCR5; RECEPTORS, CHEMOKINE; REGRESSION ANALYSIS;

EID: 33750170448     PISSN: 10641963     EISSN: 15256006     Source Type: Journal    
DOI: 10.1080/10641960600945728     Document Type: Article

References (19)

1. Ward R. Familial aggregation in genetic epidemiology of blood pressure. In: Hypertension: Pathophysiology, Diagnosis, and Management. New York: Raven Press, 1995, 67-86.
2. Hamet P. Genes and hypertension: where we are and where we should go. Clin Exp Hypertens 1999;21(5-6):947-960.
3. Dorffel Y, Latsch C, Stuhmuller B, Schreiber S, Scholze S, Burmester GR, Scholze J. Preactivated peripheral blood monocytes in patients with essential hypertension. Hypertension 1999,34(1):113-117.
4. Dzielak DJ. The immune system and hypertension. Hypertension 1992;19(Suppl. 1):I36-I44.
5. Khraibi AA. Association between disturbances in the immune system and hypertension. Am J Hypertens 1991;4:635-641.
6. Bush E, Maeda N, Kuziel WA, Dawson TC, Wilcox JN, DeLeon H, Taylor WR. CC chemokine receptor 2 is required for macrophage infiltration and vascular hypertrophy in angiotensin II-induced hypertension. Hypertension 2000;36:360-363.
7. Gerard C, Rollins BJ. Chemokines and disease. Nat Immunol February 2001;2(2):108-115.
8. Nguyen GT, Carrington M, Beeler JA, Dean M, Aledort LM, Blatt PM, Cohen AR, DiMichele D, Eyster ME, Kessler CM, Konkle B, Leissinger C, Luban N, O'Brien SJ, Goedert JJ, O'Brien TR. Phenotypic expressions of CCR5-Δ32/Δ32 homozygosity. J Acquir Immune Defic Syndr 1999;22(1):75-82.
9. Mettimano M, Specchia ML, Ianni A, Arzani D, Ricciardi G, Savi L, Romano Spica V. CCR5 and CCR2 gene polymorphisms in hypertensive patients. Br J Biomed Sci 2003;60(1):19-21.
10. WHO Guidelines Subcommittee. 1999 World Health Organisation-International Society of Hypertension guidelines for the management of hypertension. J Hypertens 1999;17(2):151-183.
11. Matsubara M, Kikuya M, Ohkubo T, Metoki H, Omori F, Fujiwara T, Suzuki M, Michimata M, Hozawa A, Katsuya T, Higaki J, Tsuji I, Araki T, Oginara T, Satoh H, Hisamichi S, Nagai K, Kitaoka H, Imai Y. Aldosterone synthase gene (CYP11B2) C-334T polymorphism, ambulatory blood pressure and nocturnal decline in blood pressure in the general Japanese population: the Ohasama Study. J Hypertens 2001;19:2179-2184.
12. Ausubel FM, et al. Current Protocols in Molecular Biology. New York: John Wiley and Sons, Inc., 1998.
13. Romano-Spica V, Ianni A, Arzani D, Cattarini L, Majore S, Dean M. Allelic distribution of CCR5 and CCR2 genes in an Italian population sample. AIDS Res Hum Retrovir 2000;16(2):99-101.
14. Eri R, Jonsson JR, Pandeya N, Purdie DM, Clouston AD, Martin N, Duffy D, Powell EE, Fawcett J, Florin TH, Radford-Smith G. CCR5-delta 32 mutation is strongly associated with primary sclerosing cholangitis. Genes Immun 2004;5(6):444-4450.
15. Ishibashi M, Hiasa K, Zhao Q, Inoue S, Ohtani K, Kitamoto S, Tsuchihashi M, Sugaya T, Charo IF, Kura S, Tsuzuki T, Ishibashi T, Takeshita A, Egashira K. Critical role of monocyte chemoattractant protein-1 receptor CCR2 on monocytes in hypertension-induced vascular inflammation and remodeling. Circulation Res 2004;14:94(9):1203-1210.
16. Izawa H, Yamada Y, Okada T, Tanaka M, Hirayama H, Yokota M. Prediction of genetic risk for hypertension. Hypertension 2003;41:1035-1040.
17. Julve R, Chaves FJ, Rovira E, Pascual JM, Miralles A, Armengod ME, Redon J. Polymorphism insertion/deletion of the ACE gene and ambulatory blood pressure circadian variability in essential hypertension. Blood Pressure Monitoring 2001;6:27-32.
18. Fujiwara T, Katsuja T, Matsubara M, Mikami T, Ishikawa K, Kikuya M, Ohkubo T, Hozawa A, Michimata M, Suzuki M, Metoki H, Asayama K, Araki T, Tsuji I, Higaki J, Satoh H, Hisamichi S, Oginara T, Imai Y. T+31C polymorphism of angiotensinogen gene and nocturnal blood pressure decline: the Ohasama study. Am J Hypertens 2002;15:628-632.
19. Imai Y, Nishiyama A, Ohkubo T, Tsuji I, Nagai K, Kikuchi N, Satoh H, Hisamichi S, et al. Factors affecting the nocturnal decrease in blood pressure: a community-based study in Ohasama. J Hypertens 1997;15:827-838.