Comparison of N-terminal pro-B-type natriuretic peptide levels in critically ill children with sepsis versus acute left ventricular dysfunction

Pediatrics

Volumn 118, Issue 4, 2006, Pages

  Fried, Iris ^a   Bar Oz, Benjamin ^a   Algur, Nurit ^b   Fried, Elchanan ^a   Gavri, Sagui ^a   Yatsiv, Ido ^a   Perles, Zeev ^a   Rein, Azaria J J T ^a   Zonis, Zeev ^c   Bass, Roman ^a   Nir, Amiram ^b  

^a HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^b SHAARE ZEDEK MEDICAL CENTER   (Israel)

^c WESTERN GALILEE HOSPITAL   (Israel)

Author keywords

B type natriuretic peptide; Children; Infants; Left ventricular dysfunction; Sepsis

Indexed keywords

BIOLOGICAL MARKER; BRAIN NATRIURETIC PEPTIDE; PEPTIDE FRAGMENT; PRO BRAIN NATRIURETIC PEPTIDE (1 76); PRO-BRAIN NATRIURETIC PEPTIDE (1-76);

ARTICLE; CHILD CARE; CLINICAL ARTICLE; CONTROLLED STUDY; CRITICAL ILLNESS; ECHOCARDIOGRAPHY; HEART LEFT VENTRICLE FAILURE; HUMAN; INFANT; INTENSIVE CARE PSYCHOSIS; PRESCHOOL CHILD; PRIORITY JOURNAL; SEPSIS; SYSTOLIC DYSFUNCTION; ACUTE DISEASE; BLOOD; CHILD; COMPARATIVE STUDY; DIFFERENTIAL DIAGNOSIS; EVALUATION; FEMALE; HEART LEFT VENTRICLE FUNCTION; MALE; NEWBORN; REFERENCE VALUE; SENSITIVITY AND SPECIFICITY;

ACUTE DISEASE; CHILD; CHILD, PRESCHOOL; CRITICAL ILLNESS; DIAGNOSIS, DIFFERENTIAL; FEMALE; HUMANS; INFANT; INFANT, NEWBORN; MALE; NATRIURETIC PEPTIDE, BRAIN; PEPTIDE FRAGMENTS; REFERENCE VALUES; SENSITIVITY AND SPECIFICITY; SEPSIS; VENTRICULAR DYSFUNCTION, LEFT;

EID: 33750122718     PISSN: 00314005     EISSN: 02105721     Source Type: Journal    
DOI: 10.1542/peds.2006-0569     Document Type: Article

References (14)

1. Baugman KL. B-type natriuretic peptide: a window to the heart. N Engl J Med. 2002;347:158-159
2. Masson S, Vago T, Baldi G, et al. Comparative measurement of N-terminal pro-brain natriuretic peptide and brain natriuretic peptide in ambulatory patients with heart failure. Clin Chem Lab Med. 2002;40:761-763
3. Nir A, Bar-Oz B, Perles Z, Brooks R, Korach A, Rein AJ. N-terminal pro-B-type natriuretic peptide: reference plasma levels from birth to adolescence - elevated levels at birth and in heart diseases. Acta Paediatr. 2004;93:603-607
4. Hoffmann U, Brueckmann M, Bertsch T, et al. Increased plasma levels of NT-proANP and NT-proBNP as markers of cardiac dysfunction in septic patients. Clin Lab. 2005;51:373-379
5. Brueckmann M, Huhle G, Lang S, et al. Prognostic value of plasma N-terminal pro-brain natriuretic peptide in patients with severe sepsis. Circulation. 2005;112:527-534
6. Jacobs RF, Darville T. Bacteremia, sepsis and septic shock. In: Rudolph CB, Rudolph AM, eds. Rudolph's Pediatrics. 21st ed. New York, NY: McGraw-Hill; 2002:896-900
7. Mir TS, Marohn S, Laer S, Eiselt M, Grollmus O, Weil J. Plasma concentrations of N-terminal pro-brain natriuretic peptide in control children from the neonatal to adolescent period and in children with congestive heart failure. Pediatrics. 2002;110(6). Available at: www.pediatrics.org/cgi/ content/full/110/6/e76
8. Hammerer-Lercher A, Neubauer E, Muller S, et al. Head-to-head comparison of N-terminal pro-brain natriuretic peptide, brain natriuretic peptide and N-terminal pro-atrial natriuretic peptide in diagnosing left ventricular dysfunction. Clin Chim Acta. 2001;310:193-197
9. Witthaut R, Busch C, Fraunberger P, et al. Plasma atrial natriuretic peptide and brain natriuretic peptide are increased in septic shock: impact of interleukin-6 and sepsis-associated left ventricular dysfunction. Intensive Care Med. 2003;29:1696-1702
10. Charpentier J, Luyt C, Fulla Y, et al. Brain natriuretic peptide: a marker of myocardial dysfunction and prognosis during severe sepsis. Crit Care Med. 2004;32:660-665
11. Ma KK, Ogawa T, de Bold AJ. Selective upregulation of cardiac brain natriuretic peptide at the transcriptional and translational levels by pro-inflammatory cytokines and by conditioned medium derived from mixed lymphocyte reactions via p38 MAP kinase. J Mol Cell Cardiol. 2004;36:505-513
12. Clerico A, Recchia FA, Passino C, et al. Cardiac endocrine function is an essential component of the homeostatic regulation network: physiological and clinical implications. Am J Physiol Heart Circ Physiol. 2006;290:H17-H29
13. Vesely DL. Natriuretic peptides and acute renal failure. Am J Physiol Renal Physiol. 2003;285:F167-F177
14. Luchner A, Hengstenberg C, Lowel H, Riegger GA, Schunkert H, Holmer S. Effect of compensated renal dysfunction on approved heart failure markers: direct comparison of brain natriuretic peptide (BNP) and N-terminal pro-BNP. Hypertension. 2005;46:118-123