Time course of changes in in vitro lipolysis of intra-abdominal fat depots in relation to high-fat diet-induced hepatic steatosis in rats

British Journal of Nutrition

Volumn 96, Issue 2, 2006, Pages 268-275

  Collin, Pascal ^a   Chapados, Natalie ^a   Dufresne, Elise ^a   Corriveau, Pierre ^a   Imbeault, Pascal ^b   Lavoie, Jean Marc ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

^b UNIVERSITY OF OTTAWA   (Canada)

Author keywords

Isoproterenol induced lipolysis; Leptin: Hepatic steatosis; Perilipin; Plasma NEFA

Indexed keywords

PERILIPIN; TRIACYLGLYCEROL; FATTY ACID; INSULIN; LEPTIN; PHOSPHOPROTEIN;

ADIPOSE TISSUE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; FATTY LIVER; FEMALE; IN VITRO STUDY; INTRAABDOMINAL FAT; LIPID ANALYSIS; LIPID DIET; LIPOLYSIS; NONHUMAN; PROTEIN CONTENT; PROTEIN DETERMINATION; RAT; RETROPERITONEAL FAT; TIME; WESTERN BLOTTING; ADIPOCYTE; ANIMAL; BLOOD; BODY WEIGHT; CELL CULTURE; FAT INTAKE; GLUCOSE BLOOD LEVEL; LIVER; METABOLISM; PATHOLOGY; SPRAGUE DAWLEY RAT;

RATTUS;

ADIPOCYTES; ANIMALS; BLOOD GLUCOSE; BODY WEIGHT; CELLS, CULTURED; DIETARY FATS; FATTY ACIDS, NONESTERIFIED; FATTY LIVER; FEMALE; INSULIN; INTRA-ABDOMINAL FAT; LEPTIN; LIPOLYSIS; LIVER; PHOSPHOPROTEINS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 33750108341     PISSN: 00071145     EISSN: 14752662     Source Type: Journal    
DOI: 10.1079/BJN20061775     Document Type: Article

References (30)

1. Bellantani S, Saccoccio G, Masutti F, Croce LS, Brandi G, Sasso F, Cristanini G & Tiribelli C (2000) Prevalence and risk factors for hepatic steatosis in Northern Italy. Ann Intern Med 132, 112-117.
2. Berger JJ & Barnard RJ (1999) Effect of diet on fat cell size and hormone-sensitive lipase activity. J Appl Physiol 87, 227-232.
3. Brasaemle DL, Rubin B, Harten IA, Gruia-Gray J, Kimmel AR & Londos C (2000) Perilipin A increases triacylglycerol storage by decreasing the rate of triacyglycerol hydrolysis. J Biol Chem 275, 38486-38493.
4. Chitturi S & Farrell GC (2001) Etiopathogenesis of non-alcoholic steatohepatitis. Semin Liver Dis 21, 27-41.
5. Enevoldsen LH, Stallknecht B, Fluckey JD & Galbo C (2000) Effect of exercise training on in vivo lipolysis in intra-abdominal adipose tissue in rats. Am J Physiol Endocrinol Metab 279, E585-E592.
6. Festi D, Colecchia A, Sacco T, Bondi M, Roda E & Marchesini G (2004) Hepatic steatosis in obese patients: Clinical aspects and prognostic significance. Obes, Rev 5, 27-42.
7. Frayn KN (2000) Visceral fat and insulin resistance - causative or correlative? Br J Nutr 83, S71-S77.
8. Frayn KN & Maycock PF (1980) Skeletal muscle triacylglycerol in the rat: methods for sampling and measurement and studies of biological variability. J Lipid Res 21, 139-144.
9. Gauthier M-S, Couturier K, Charbonneau A & Lavoie J-M (2004) Effects of introducing physical training in the course of a 16-week high-fat diet regimen on hepatic steatosis, adipose tissue fat accumulation, and plasma lipid profile. Int J Obes 28, 1064-1071.
10. Gauthier M-S, Couturier K, Latour JG & Lavoie J-M (2003) Concurrent exercise prevents high-fat-diet-induced macrovesicular hepatic steatosis. J Appl Physiol 94, 2127-2134.
11. Gauthier M-S, Favier R & Lavoie J-M (2006) Time course of the development of non-alcoholic hepatic steatosis in response to high-fat diet-induced obesity in rats. Br J Nutr 95, 273-281.
12. Greenberg AS, Egan JJ, Wek SA, Garty NB, Blanchette-Mackie EJ & Londos C (1991) Perilipin, a major hormonally regulated adipocyte specific phosphoprotein associated with the periphery of lipid storage droplets. J Biol Chem 266, 11341-11346.
13. Havel RJ & Hamilton RL (2004) Hepatic catabolism of remnant lipoproteins: Where the action is. Arterioscler Thromb Vasc Biol 24, 213-215.
14. James O & Day C (1999) Non-alcoholic steatohepatitis. Another disease of affluence. Lancet 353, 1634-1636.
15. Kraegen EW, Clark PW, Jenkins AB, Daley EA, Chisholm DJ & Storlien LH (1991) Development of muscle insulin resistance after liver insulin resistance in high-fat-fed rats. Diabetes 40, 1397-1403.
16. Large V & Amer P (1998) Regulation of lypolysis in humans. Pathophysiological modulation in obesity, diabetes, and hyperlipidaemia. Diabetes Metab 24, 409-418.
17. Lewis GF, Carpentier A, Adeli K & Giacca A (2002) Disordered fat storage and mobilization in the pathogenesis of insulin resistance and type 2 diabetes. Endocrine Rev 23, 201-229.
18. Londos C, Brasaemle DJ, Schultz CJ, Segrest JP & Kimmel AR (1999) Perilipins, ADRP, and other proteins that associate with intracellular neutral lipid droplets in animal cells. Semin Cell Dev Biol 10, 51-58.
19. Londos C, Sztalryd C, Tansey JT & Kimmel AR (2005) Role of PAT proteins in lipid metabolism. Biochimie 87, 45-49.
20. Marchesini G, Brizi M, Bianchi G, Tomassetti S, Bugianesi E, Lenzi M, McCullogh AJ, Natale S, Forlani G & Melchionda N (2001) Nonalcoholic fatty liver disease. A feature of the metabolic syndrome. Diabetes 50, 1844-1850.
21. Miles JM, Park YS, Walewicz D, Russell-Lopez C, Windsor S, Isley WL, Coppack SW & Harris WS (2004) Systemic and forearm triglyceride metabolism: Fate of lipoprotein lipase-generated glycerol and free fatty acids. Diabetes 53, 521-527.
22. Mottagui-Tabar S, Ryden M, Lofgren P, Faulds G, Hoffstedt J, Brookes AJ, Andersson I & Arner P (2003) Evidence for an important role of perilipin in the regulation of human adipocyte lipolysis. Diabetologia 46, 789-797.
23. Must A, Spadano J, Coakley EH, Field AE, Colditz G & Dietz WH (1999) The disease burden associated with overweight and obesity. JAMA 282, 1523-1529.
24. Riemens SC, Sluiter WJ & Dullaart RP (2000) Enhanced escape of non-esterified fatty acids from tissue uptake: Its role in impaired insulin-induced lowering of total rate of appearance in obesity and type 2 diabetes mellitus. Diabetologia 43, 416-426.
25. Rodbell M (1964) Metabolism of isolated fat cells I. Effects of hormones on glucose metabolism and lipolysis. J Biol Chem 239, 375-380.
26. Samuel VT, Liu Z-X, Qu X, Elder BD, Bilz S, Belfroy D, Romanelli AJ & Shulman GI (2004) Mechanism of hepatic insulin resistance in non-alcoholic fatty liver disease. J Biol Chem 279, 32345-32353.
27. Scheen AJ & Luyckx FH (2002) Obesity and liver disease. Best Pract-Res Clin Endocrinol Met 16, 703-716.
28. Sniderman AD, Cianflone K, Arner P, Summers LKM & Frayn KN (1998) The adipocyte, fatty acid trapping, and atherogenesis. Arterioscler Thromb Vasc Biol 18, 147-151.
29. Sztalryd C, Xu G, Dorward H, Tansey JT, Contreras JA, Kimmel AR & Londos C (2003) Perilipin A is essential for the translocation of hormone-sensitive lipase during lipolytic activation. J Cell Biol 161, 1011-1012.
30. Wang Y, Sullivan S, Trujillo M, Lee M-J, Schneider S, Brolin RE, Kang YH, Werber Y, Greenberg AS & Fried SK (2003) Perilipin expression in human adipose tissues: Effects of severe obesity, gender, and depot. Obes Res 11, 930-936.