A new dihydroxanthenone from a plant-associated strain of the fungus Chaetomium globosum demonstrates anticancer activity

Bioorganic and Medicinal Chemistry

Volumn 14, Issue 23, 2006, Pages 7917-7923

  Wijeratne, E M Kithsiri ^a   Turbyville, Thomas J ^a,b   Fritz, Anne ^a   Whitesell, Luke ^b   Gunatilaka, A A Leslie ^a  

^a School of Natural Resources and the Environment   (United States)

^b UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

Author keywords

Cell cycle disruptor; Chaetomium globosum; Cytotoxicity; Globosuxanthones A D; Opuntia leptocaulis; Plant associated fungus

Indexed keywords

CYTOTOXIC AGENT; DIHYDROXANTHENONE; GLOBOSUXANTHONE A; GLOBOSUXANTHONE B; GLOBOSUXANTHONE C; GLOBOSUXANTHONE D; UNCLASSIFIED DRUG; XANTHONE DERIVATIVE;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE S PHASE; CHAETOMIUM; CHAETOMIUM GLOBOSUM; CONTROLLED STUDY; CYTOTOXICITY; HUMAN; HUMAN CELL; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RHIZOSPHERE; SOLID TUMOR; X RAY CRYSTALLOGRAPHY;

ANTHRAQUINONES; ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL CYCLE; CELL LINE, TUMOR; CHAETOMIUM; DRUG SCREENING ASSAYS, ANTITUMOR; HUMANS; MOLECULAR STRUCTURE; STEREOISOMERISM; XANTHENES;

CHAETOMIUM GLOBOSUM; FUNGI; OPUNTIA LEPTOCAULIS;

EID: 33750090717     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2006.07.048     Document Type: Article

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