Physico-chemical characterization and in vivo evaluation of indomethacin ethyl ester-loaded nanocapsules by PCS, TEM, SAXS, interfacial alkaline hydrolysis and antiedematogenic activity

Journal of Nanoscience and Nanotechnology

Volumn 6, Issue 9-10, 2006, Pages 3154-3162

  Cruz, Letícia ^a   Schaffazick, Scheila R ^a   Costa, Teresa Dalla ^a   Soares, Leonardo U ^a   Mezzalira, Graziela ^a   Da Silveira, Nádya P ^a   Schapoval, Elfrides E S ^a   Pohlmann, Adriana R ^a   Guterres, Sílvia S ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Alkaline Hydrolysis; Antiedematogenic Activity; Indomethacin; Mathematical Modeling; Polymeric Nanocapsules; Release; SAXS

Indexed keywords

ALKALINE HYDROLYSIS; ANTIEDEMATOGENIC ACTIVITY; NANOCAPSULES; NANOEMULSION; POLYMERIC WALL;

CONCENTRATION (PROCESS); DRUG PRODUCTS; HYDROLYSIS; MATHEMATICAL MODELS; NANOSTRUCTURED MATERIALS; PHARMACOKINETICS; POLYMERS; SURFACE ACTIVE AGENTS;

ESTERIFICATION;

ALKALI; DRUG DERIVATIVE; INDOMETACIN; INDOMETHACIN ETHYL ESTER; NANOMATERIAL; NONSTEROID ANTIINFLAMMATORY AGENT;

ANIMAL; ARTICLE; CHEMISTRY; CONFORMATION; EDEMA; EVALUATION; HYDROLYSIS; MALE; MICROCAPSULE; PARTICLE SIZE; PATHOLOGY; RAT; TRANSMISSION ELECTRON MICROSCOPY; TREATMENT OUTCOME; ULTRASTRUCTURE; WISTAR RAT; X RAY DIFFRACTION;

ALKALIES; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CAPSULES; EDEMA; HYDROLYSIS; INDOMETHACIN; MALE; MICROSCOPY, ELECTRON, TRANSMISSION; MOLECULAR CONFORMATION; NANOSTRUCTURES; PARTICLE SIZE; RATS; RATS, WISTAR; TREATMENT OUTCOME; X-RAY DIFFRACTION;

EID: 33750090086     PISSN: 15334880     EISSN: None     Source Type: Journal    
DOI: 10.1166/jnn.2006.417     Document Type: Conference Paper

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