Parallel synthesis of diarylureas and their evaluation as inhibitors of insulin-like growth factor receptor

Journal of Combinatorial Chemistry

Volumn 8, Issue 5, 2006, Pages 784-790

  Anderson, Marc O ^a   Yu, Hong ^a   Penaranda, Cristina ^a   Maddux, Betty A ^a   Goldfine, Ira D ^a   Youngren, Jack F ^a   Guy, R Kiplin ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN KINASE INHIBITOR; SOMATOMEDIN C RECEPTOR; UREA;

ANIMAL; ARTICLE; CHEMISTRY; CHO CELL; COMBINATORIAL CHEMISTRY; CRICETULUS; DRUG ANTAGONISM; HAMSTER; HUMAN; SYNTHESIS;

ANIMALS; CHO CELLS; COMBINATORIAL CHEMISTRY TECHNIQUES; CRICETINAE; CRICETULUS; HUMANS; PROTEIN KINASE INHIBITORS; RECEPTOR, IGF TYPE 1; UREA;

EID: 33750081128     PISSN: 15204766     EISSN: None     Source Type: Journal    
DOI: 10.1021/cc050136z     Document Type: Article

References (19)

1. LeRoith, D.; Helman, L. Cancer Cell 2004, 5, 201-2.
2. Mazitschek, R.; Giannis, A. Curr. Opin. Chem. Biol. 2004, 8, 432-41.
3. Morin, M. J. Oncogene 2000, 19, 6574-83.
4. Arteaga, C. L.; Kitten, L. J.; Coronado, E. B.; Jacobs, S.; Kull, F. C., Jr.; Allred, D. C.; Osborne, C. K. J. Clin. Invest. 1989, 84, 1418-23.
5. Firth, S. M.; Baxter, R. C. Endocrine Rev. 2002, 23, 824-54.
6. Pietrzkowski, Z.; Mulholland, G.; Gomella, L.; Jameson, B. A.; Wernicke, D.; Baserga, R. Cancer Res. 1993, 53, 1102-6.
7. Blum, G.; Gazit, A.; Levitzki, A. Biochemistry 2000, 39, 15705-12.
8. Blum, G.; Gazit, A.; Levitzki, A. J. Biol. Chem. 2003, 278, 40442-54.
9. Mitsiades, C. S.; Mitsiades, N. S.; McMullan, C. J.; Poulaki, V.; Shringarpure, R.; Akiyama, M.; Hideshima, T.; Chauhan, D.; Joseph, M.; Libermann, T. A.; Garcia-Echeverria, C.; Pearson, M. A.; Hofmann, F.; Anderson, K. C.; Kung, A. L. Cancer Cell 2004, 5, 221-30.
10. Gable, K. L.; Maddux, B. A.; Penaranda, C.; Zavodovskaya, M.; Campbell, M. J.; Lobo, M.; Robinson, L.; Schow, S.; Kerner, J. A.; Goldfine, I. D.; Youngren, J. F. Mol. Cancer Ther. 2006, 5, 1079-86.
11. Larock, R. C. Comprehensive Organic Transformations: A Guide to Functional Group Preparations, 2nd ed.; VCH Publishers: New York, NY, 1999.
12. Bartolozzi, A.; Grogan, M. J.; Kates, S. A. Methods Enzymol. 2003, 369, 347-66.
13. Edwards, P. J. Comb. Chem. High Throughput Screening 2003, 6, 11-27.
14. Garcia, J. G. Methods Enzymol. 2003, 369, 391-412.
15. Pender, C.; Goldfine, I. D.; Manchem, V. P.; Evans, J. L.; Spevak, W. R.; Shi, S.; Rao, S.; Bajjalieh, S.; Maddux, B. A.; Youngren, J. F. J. Biol. Chem. 2002, 277, 43565-71.
16. Letot, E.; Koch, G.; Falchetto, R.; Bovermann, G.; Oberer, L.; Roth, H. J. J. Comb. Chem. 2005, 7, 364-71.
17. Yan, B.; Fang, L.; Irving, M.; Zhang, S.; Boldi, A. M.; Woolard, F.; Johnson, C. R.; Kshirsagar, T.; Figliozzi, G. M.; Krueger, C. A.; Collins, N. J. Comb. Chem. 2003, 5, 547-59.
18. Taylor, E. W.; Qian, M. G.; Dollinger, G. D. Anal. Chem. 1998, 70, 3339-3347.
19. Purchased from CalBiochem.