Gene expression changes during step-wise differentiation of embryonic stem cells along the inner ear hair cell pathway

Acta Oto-Laryngologica

Volumn 126, Issue 11, 2006, Pages 1148-1157

  De Silva, Michelle G ^a   Hildebrand, Michael S ^a,b   Christopoulos, Helen ^a   Newman, Michelle R ^a   Bell, Katrina ^a   Ritchie, Matthew ^c   Smyth, Gordon K ^c   Dahl, Hans Henrik M ^a,b  

^a ROYAL CHILDREN'S HOSPITAL   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

Embryonic stem cell differentiation; Epidermal growth factor; Hair cell development; Microarray expression profile

Indexed keywords

CYSTEINE; EPIDERMAL GROWTH FACTOR; GLUCOSE TRANSPORTER; OSTEONECTIN; PROTEIN SERPINH1; PROTEIN SLC2A10; PROTEINASE INHIBITOR; SERINE; SERINE PROTEINASE INHIBITOR; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL LINEAGE; CELL PROLIFERATION; CELL TYPE; CONTROLLED STUDY; CORTI ORGAN; DNA LIBRARY; DNA MICROARRAY; ECTODERM; EMBRYONIC STEM CELL; GENE; GENE EXPRESSION REGULATION; GENETIC SELECTION; HAIR CELL; INNER EAR; MOUSE; NEUROECTODERM; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; SERPINH1 GENE; SLC2A10 GENE;

ANIMALS; CELL DIFFERENTIATION; CELL DIVISION; CELL LINE; EMBRYONIC STEM CELLS; EPIDERMAL GROWTH FACTOR; GENE EXPRESSION REGULATION; GLUCOSE TRANSPORT PROTEINS, FACILITATIVE; HAIR CELLS, AUDITORY, INNER; HAIR CELLS, INNER; HSP47 HEAT-SHOCK PROTEINS; MICE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; ORGAN OF CORTI; OSTEONECTIN; PLURIPOTENT STEM CELLS; TISSUE ENGINEERING; UP-REGULATION;

EID: 33750070326     PISSN: 00016489     EISSN: 16512553     Source Type: Journal    
DOI: 10.1080/00016480600702118     Document Type: Article

References (23)

1. Malgrange B, Belachew S, Thiry M, Nguyen L, Rogister B, Alvarez ML, et al. Proliferative generation of mammalian auditory hair cells in culture. Mech Dev 2002;112:79-88.
2. Doetzlhofer A, White PM, Johnson JE, Segil N, Groves AK. In vitro growth and differentiation of mammalian sensory hair cell progenitors: a requirement for EGF and periotic mesenchyme. Dev Biol 2004;272:432-47.
3. Rathjen J, Lake JA, Bettess MD, Washington JM, Chapman G, Rathjen PD. Formation of a primitive ectoderm like cell population, EPL cells, from ES cells in response to biologically derived factors. J Cell Sci 1999;112(Pt 5):601-12.
4. Rathjen J, Haines BP, Hudson KM, Nesci A, Dunn S, Rathjen PD. Directed differentiation of pluripotent cells to neural lineages: homogeneous formation and differentiation of a neurectoderm population. Development 2002;129: 2649-61.
5. Smyth G, Yang Y, Speed T. Statistical issues in cDNA microarray data analysis. New Jersey: Humana Press; 2002.
6. Yang YH, Dudoit S, Luu P, Speed TP. Normalization for cDNA microarry data. In: Bittner ML, Chen Y, Dorsel AN, Dougherty ER, eds. Microarrays: optical technologies and informatics; 2001. SPIE, 2001:141-52.
7. Lonnstedt I, Speed TP. Replicated microarray data. Statistica Sinica 2001;12:31-46.
8. Whitlon DS, Szakaly R, Greiner MA. Cryoembedding and sectioning of cochleas for immunocytochemistry and in situ hybridization. Brain Res Brain Res Protoc 2001;6:159-66.
9. Myat A, Henrique D, Ish-Horowicz D, Lewis J. A chick homologue of Serrate and its relationship with Notch and Delta homologues during central neurogenesis. Dev Biol 1996;174:233-47.
10. Mothe AJ, Brown IR. Expression of mRNA encoding extracellular matrix glycoproteins SPARC and SC1 is temporally and spatially regulated in the developing cochlea of the rat inner ear. Hear Res 2001;155:161-74.
11. Chen P, Johnson JE, Zoghbi HY, Segil N. The role of Math1 in inner ear development: Uncoupling the establishment of the sensory primordium from hair cell fate determination. Development 2002;129:2495-505.
12. Yagil C, Hubner N, Monti J, Schulz H, Sapojnikov M, Luft FC, et al. Identification of hypertension-related genes through an integrated genomic-transcriptomic approach. Expression of genes involved in vascular development and angiogenesis in endothelial cells of adult lung. Circ Res 2005;96:617-25.
13. Favre CJ, Mancuso M, Maas K, McLean JW, Baluk P, McDonald DM. Expression of genes involved in vascular development and angiogenesis in endothelial cells of adult lung. Am J Physiol Heart Circ Physiol 2003;285:H1917-38.
14. Nagai N, Hosokawa M, Itohara S, Adachi E, Matsushita T, Hosokawa N, et al. Embryonic lethality of molecular chaperone hsp47 knockout mice is associated with defects in collagen biosynthesis. J Cell Biol 2000;150:1499-506.
15. McVie-Wylie AJ, Lamson DR, Chen YT. Molecular cloning of a novel member of the GLUT family of transporters, SLC2a10 (GLUT10), localized on chromosome 20q13.1: a candidate gene for NIDDM susceptibility. Genomics 2001; 72:113-7.
16. Chambard JM, Ashmore JF. Sugar transport by mammalian members of the SLC26 superfamily of anion-bicarbonate exchangers. J Physiol 2003;550(Pt 3):667-77.
17. Yoshihara T, Satoh M, Yamamura Y, Itoh H, Ishii T. Ultrastructural localization of glucose transporter 1 (GLUT1) in guinea pig stria vascularis and vestibular dark cell areas: an immunogold study. Acta Otolaryngol (Stockh) 1999;119:336-40.
18. Abe S, Katagiri T, Saito-Hisaminato A, Usami S, Inoue Y, Tsunoda T, et al. Identification of CRYM as a candidate responsible for nonsyndromic deafness, through cDNA microarray analysis of human cochlear and vestibular tissues. Am J Hum Genet 2003;72:73-82.
19. Iijima N, Suzuki N, Oguchi T, Hashimoto S, Takumi Y, Sugahara K, et al. The effect of hypergravity on the inner ear: CREB and syntaxin are up-regulated. Neuroreport 2004;15: 965-9.
20. Hildebrand MS, de Silva MG, Klockars T, Rose E, Price M, Smith RJ, et al. Characterisation of DRASIC in the mouse inner ear. Hear Res 2004;190:149-60.
21. Hildebrand MS, de Silva MG, Klockars T, Solares CA, Hirose K, Smith JD, et al. Expression of the carrier protein apolipoprotein D in the mouse inner ear. Hear Res 2005; 200:102-14.
22. Chen ZY, Corey DP. An inner ear gene expression database. J Assoc Res Otolaryngol 2002;3:140-8.
23. Heller S. Molecular screens for inner ear genes. J Neurobiol 2002;53:265-75.