α-cyclisation of tertiary amines: Synthesis of some novel annelated quinolines via a three-component reaction under solvent-free conditions

Synlett

Volumn , Issue 16, 2006, Pages 2593-2596

  Devi, Ipsita ^a   Baruah, Biswajita ^a   Bhuyan, Pulak J ^a  

^a REGIONAL RESEARCH LABORATORY   (India)

Author keywords

Multicomponent reaction; Pyrimidines; Quinolines; Solvent free reaction; Tertiary amine effect

Indexed keywords

1,4 OXAZINE DERIVATIVE; ACETANILIDE DERIVATIVE; CAMPTOTHECIN; INDOLIZINE DERIVATIVE; QUINOLINE DERIVATIVE; QUINOLIZINE DERIVATIVE; TERTIARY AMINE;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; CYCLIZATION; SOLID; SYNTHESIS;

EID: 33750068317     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2006-951477     Document Type: Article

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37. 2O and dried. The crude compound was then recrystallised from EtOAc. Yield: 80% (1.62 g); mp 142-143 °C. Similarly compounds 2b-d were synthesised and characterised.
38. +. Similarly compounds 5b-j and 7a-f were synthesised and characterised.
39. 2, 4 H), 6.9-7.6 (Ph, 5 H), 8.2 (CH, 1 H), 9.8 (CHO, 1 H).
40. 2, 4 H), 7.0-7.8 (Ph, 5 H), 8.5 (CH, 1 H). Yield: 1.24 g (88.5%). Similarly compounds 9b and 9c were synthesised and characterised.
41. 3-hexane, 2:1) to give a brown solid. Similarly compounds 5e, 5i and 7a were synthesised and characterised.