Cellular effects and metabolic stability of N1-cyclic inosine diphosphoribose and its derivatives

British Journal of Pharmacology

Volumn 149, Issue 4, 2006, Pages 337-344

  Kirchberger, T ^a   Wagner, G ^b   Xu, J ^c   Cordiglieri, C ^d   Wang, P ^c   Gasser, A ^a   Fliegert, R ^a   Bruhn, S ^a   Flugel A ^d   Lund, F E ^e   Zhang, L H ^c   Potter, B V L ^b   Guse, A H ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^b University of Bath   (United Kingdom)

^c PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^d MAX PLANCK INSTITUTE OF NEUROBIOLOGY   (Germany)

^e TRUDEAU INSTITUTE   (United States)

Author keywords

ADP ribosyl cyclase; Calcium signalling; CD38; Cyclic ADP ribose; Cytokine expression; Primary T cell; Proliferation; Signal transduction; Stable analogues; T lymphoma cell

Indexed keywords

8 BROMO CYCLOINOSINE 5' DIPHOSPHORIBOSE; ADENOSINE; ADENOSINE DIPHOSPHATE RIBOSE; ADENOSINE DIPHOSPHATE RIBOSYL CYCLASE; ANTINEOPLASTIC AGENT; CALCIUM ION; CD38 ANTIGEN; CYCLIC ADENOSINE DIPHOSPHATE RIBOSE; CYTOKINE; INOSINE; INOSINE DIPHOSPHATE; N1 [(PHOSPHORYL O ETHOXY)METHYL] N9 [(PHOSPHORYL O ETHOXY)METHYL]HYPOXANTHINE CYCLOPYROPHOSPHATE; N1 CYCLIC INOSINE DIPHOSPHORIBOSE; N1 CYCLIC INOSINE DIPHOSPHORIBOSE DERIVATIVE; N1 ETHOXYMETHYL CYCLOINOSINE 5' DIPHOSPHORIBOSE; NICOTINAMIDE ADENINE DINUCLEOTIDE NUCLEOSIDASE; RIBOSE PHOSPHATE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM SIGNALING; CELL PROLIFERATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG DESIGN; DRUG HYDROLYSIS; DRUG MECHANISM; DRUG METABOLISM; DRUG STABILITY; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LYMPHOCYTE PROLIFERATION; LYMPHOMA CELL; NONHUMAN; PRIORITY JOURNAL; RAT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; SECOND MESSENGER; T LYMPHOCYTE;

ADP-RIBOSYL CYCLASE; ANTIGENS, CD38; ANTINEOPLASTIC AGENTS; CALCIUM; CELL PROLIFERATION; CYCLIC ADP-RIBOSE; CYTOKINES; HUMANS; HYDROLYSIS; INOSINE NUCLEOTIDES; JURKAT CELLS; NAD+ NUCLEOSIDASE; SIGNAL TRANSDUCTION; T-LYMPHOCYTES;

EID: 33750067718     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706869     Document Type: Article

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