Common variants of Cholesteryl ester transfer protein gene and their association with lipid parameters in healthy volunteers of Tamilian population

Clinica Chimica Acta

Volumn 375, Issue 1-2, 2007, Pages 140-146

  Padmaja, N ^a   Ravindra Kumar, M ^a   Soya, S S ^a   Adithan, C ^a  

^a JAWAHARLAL INSTITUTE OF POSTGRADUATE MEDICAL EDUCATION AND RESEARCH   (India)

Author keywords

CETP; Genotyping; HDL C; PCR RFLP; Polymorphism; Tamilian population

Indexed keywords

CHOLESTEROL ESTER TRANSFER PROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ADULT; AFRICAN AMERICAN; ARTICLE; CHOLESTEROL BLOOD LEVEL; ETHNIC GROUP; EUROPEAN AMERICAN; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HUMAN; HUMAN CELL; INDIA; LIPID BLOOD LEVEL; MALE; NORMAL HUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN VARIANT; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; TRIACYLGLYCEROL BLOOD LEVEL;

CHOLESTEROL ESTER TRANSFER PROTEINS; FEMALE; GENE FREQUENCY; GENOTYPE; HUMANS; INDIA; LIPIDS; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC;

EID: 33750055746     PISSN: 00098981     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cca.2006.06.031     Document Type: Article

References (37)

1. Ohashi R., Mu H., Wang X., Yao Q., and Chen C. Reverse cholesterol transport and cholesterol efflux in atherosclerosis. QJM 98 (2005) 845-856
2. Ruggeri R.B. Cholesteryl ester transfer protein: pharmacological inhibition for the modulation of plasma cholesterol concentrations and promising target for the prevention of atherosclerosis. Curr Top Med Chem 5 (2005) 257-264
3. Inazu A., Brown M.L., Hesler C.B., et al. Increased high density lipoprotein concentrations caused by a common cholesteryl-ester transfer protein gene mutation. N Engl J Med 323 (1990) 1234-1238
4. van der Steeg W.A., Kuivenhoven J.A., Klerkx A.H., Boekholdt S.M., Hovingh G.K., and Kastelein J.J. Role of CETP inhibitors in the treatment of dyslipidemia. Curr Opin Lipidol 15 (2004) 631-636
5. Lloyd D.B., Lira M.E., Wood L.S., et al. Cholesteryl ester transfer protein variants have differential stability but uniform inhibition by torcetrapib. J Biol Chem 280 (2005) 14918-14922
6. Blankenberg S., Rupprecht H.J., Bickel C., et al. Common Genetic variation of the cholesteryl ester transfer protein gene strongly predicts cardiovascular death in patients with coronary artery disease. J Am Coll Cardiol (2003) 1983-1989
7. Kondo I., Berg K., Drayna D.T., and Lawn R.M. DNA polymorphism at the locus for human cholesteryl ester transfer protein (CETP) is associated with high density lipoprotein cholesterol and apolipoprotein concentrations. Clin Genet 35 (1989) 49-56
8. Boekholdt S.M., and Thompson J.F. Natural genetic variation as a tool in understanding the role of CETP in lipid concentrations and disease. J Lipid Res 44 (2003) 1080-1093
9. Dachet C., Poirier O., Cambien F., Chapman J., and Rouis M. New functional promoter polymorphism, CETP/-629, in cholesteryl ester transfer protein (CETP) gene related to CETP mass and high density lipoprotein cholesterol concentrations: role of Sp1/Sp3 in transcriptional regulation. Arterioscler Thromb Vasc Biol 20 (2000) 507-515
10. Eiriksdottir G., Bolla M.K., Thorsson B., Sigurdsson G., Humphries S.E., and Gudnason V. The -629C-A polymorphism in the CETP gene does not explain the association of TaqIB polymorphism with risk and age of myocardial infarction in Icelandic men. Atherosclerosis 159 (2001) 187-192
11. Kakko S., Tamminen M., Paivansalo M., et al. Variation at the cholesteryl ester transfer protein gene in relation to plasma high density lipoproteins cholesterol concentrations and carotid intima-media thickness. Eur J Clin Invest 31 (2001) 593-602
12. Agellon L.B., Quinet E.M., Gillette T.G., et al. Organization of the human cholesteryl ester transfer protein gene. Biochemistry 29 (1990) 1372-1376
13. Okumura K., Matsui H., Kamiya H., et al. Differential effect of two common polymorphisms in the cholesteryl ester transfer protein gene on low-density lipoprotein particle size. Atherosclerosis 161 (2002) 425-431
14. Mendis S., Shepherd J., Packard C.J., and Gaffriey D. Genetic variation in the cholesteryl ester transfer protein and apolipoprotein A-I genes and its relation to coronary heart disease in a Sri Lankan population. Atherosclerosis 83 (1990) 21-27
15. Takahashi K., Jiang X.C., Sakai N., et al. A missense mutation in the cholesteryl ester transfer protein gene with possible dominant effects on plasma high density lipoproteins. J Clin Invest 92 (1993) 2060-2064
16. Freeman D.J., Griffin B.A., Holmes A.P., et al. Regulation of plasma HDL cholesterol and subfraction distribution by genetic and environmental factors. Associations between the TaqIB RFLP in the CETP gene and smoking and obesity. Arterioscler Thromb 14 (1994) 336-344
17. Kuivenhoven J.A., de Knijff P., Boer J.M., et al. Heterogeneity at the CETP gene locus. Influence on plasma CETP concentrations and HDL cholesterol concentrations. Arterioscler Thromb Vasc Biol 17 (1997) 560-568
18. Gudnason V., Kakko S., Nicaud V., et al. Cholesteryl ester transfer protein gene effect on CETP activity and plasma high-density lipoprotein in European populations. The EARS Group. Eur J Clin Invest 29 (1999) 116-128
19. Heiba I.M., DeMeester C.A., Xia Y.R., et al. Genetic contributions to quantitative lipoprotein traits associated with coronary artery disease: analysis of a large pedigree from the Bogalusa Heart Study. Am J Med Genet 47 (1993) 875-883
20. Tai E.S., Ordovas J.M., Corella D., et al. The TaqIB and -629C>A polymorphisms at the cholesteryl ester transfer protein locus: associations with lipid concentrations in a multiethnic population. The 1998 Singapore National Health Survey. Clin Genet 63 (2003) 19-30
21. Begom R., and Singh R.B. Prevalence of coronary artery disease and its risk factors in the urban population of South and North India. Acta Cardiol 50 (1995) 227-240
22. Rissam H.S., Kishore S., and Trehan N. Coronary artery disease in young Indians-the missing link. J Indian Acad Clin Med 2 (2001) 128-132
23. Friedewald W.T., Levy R.I., and Fredrickson D.S. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem 18 (1972) 499-502
24. Ordovas J.M., Cupples A., Corella D., et al. Association of cholesteryl ester transfer protein-Taq1B polymorphism with variations in lipoprotein subclasses and coronary heart disease risk. The Framingham study. Arterioscler Thromb Vasc Biol 20 (2000) 1323-1329
25. Wu J.H., Lee Y.T., Hsu H.C., and Hseih L.L. Influence of CETP gene variation on plasma lipid concentrations and coronary heart disease: a survey in Taiwan. Atherosclerosis 159 (2001) 451-458
26. Cuchel M., Wolfe M.L., deLemos A.S., and Rader D.J. The frequency of the cholesteryl ester transfer protein-TaqI B2 allele is lower in African Americans than in Caucasians. Atherosclerosis 163 (2002) 169-174
27. Dixit M., and Mittal B. Frequencies of CETP gene TaqIB and D442G polymorphisms in North Indian population. Curr Sci 88 (2005) 1973-1976
28. Kuivenhoven J.A., Jukema J.W., Zwinderman A.H., et al. The role of a common variant of the cholesteryl ester protein gene in the progression of coronary atherosclerosis. The Regression Growth Evaluation Statin Study Group. N Engl J Med 338 (1998) 86-93
29. Freeman D.J., Samani N.J., Wilson V., et al. A polymorphism of the cholesteryl ester transfer protein gene predicts cardiovascular events in non-smokers in the West of Scotland Coronary Prevention Study. Eur Heart J 24 (2003) 1833-1842
30. Liu S., Schmitz C., Stampfer M.J., et al. A prospective study of TaqIB polymorphism in the gene coding for cholesteryl ester transfer protein and risk of myocardial infarction in middle-aged men. Atherosclerosis 161 (2002) 469-474
31. Klerkx A.H., Tanck M.W., Kastelein J.J., et al. Haplotype analysis of the CETP gene: not TaqIB, but the closely linked -629C->A polymorphism and a novel promoter variant are independently associated with CETP concentration. Hum Mol Genet 15 12 (2003) 111-123
32. Durlach A., Clavel C., Globa G.A., and Durlach V. Sex-dependent association of a genetic polymorphism of cholesteryl ester transfer protein with high-density Lipoprotein cholesterol and macrovascular pathology in Type II diabetic patients. J Clin Endocrinol Metab 84 (1999) 3656-3659
33. Thompson J.F., Durham L.K., Lira M.E., Shear C., and Milos P.M. CETP polymorphisms associated with HDL cholesterol may differ from those associated with cardiovascular disease. Atherosclerosis 181 (2005) 45-53
34. Larsen A.B., Nordestgaard B.G., Steffensen R., et al. Elevated HDL cholesterol is a risk factor for ischemic heart disease in white women when caused by a common mutation in the cholesteryl ester transfer protein gene. Circulation 25 101 (2000) 1907-1912
35. Bruce C., Sharp D.S., and Tall A.R. Relationship of HDL and coronary heart disease to a common amino acid polymorphism in the cholesteryl ester transfer protein in men with and without hypertriglyceridemia. J Lipid Res 39 (1998) 1071-1078
36. Van Venrooij F.V., Stolk R.P., Banga J.D., et al. Common cholesteryl ester transfer protein gene polymorphisms and the effect of atorvastatin therapy in type 2 diabetes. Diabetes Care 26 (2003) 1216-1223
37. Arai H., Yamamoto A., Matsuzawa Y., and Saito Y. Polymorphisms in tour genes related to triglyceride and HDL-cholesterol concentrations in the general Japanese population in 2000. J Atheroscler Thromb 12 (2005) 240-250