Systemic distribution and elimination of plain and with Cy3.5 functionalized poly(vinyl alcohol) coated superparamagnetic maghemite nanoparticles after intraarticular injection in sheep in vivo

Journal of Nanoscience and Nanotechnology

Volumn 6, Issue 9-10, 2006, Pages 3261-3268

  Hellstern, Daniel ^a   Schulze, Katja ^a   Schöpf, Bernhard ^a   Petri Fink, Alke ^b   Steitz, Benedikt ^b   Kamau, Sarah ^a   Hilbe, Monika ^a   Koch Schneidemann, Sabine ^a   Vaughan, Lloyd ^a   Hottiger, Michael ^a   Hofmann, Margarethe ^c   Hofmann, Heinrich ^b   Von Rechenberg, Brigitte ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b EPFL   (Switzerland)

^c MatSearch   (Switzerland)

Author keywords

Confocal Microscopy; Fluorescent Microscopy; Poly(vinyl alcohol)

Indexed keywords

CONFOCAL MICROSCOPY; FLUORESCENT MICROSCOPY; INTRAARTICULAR INJECTION; PHYSIOLOGIC IRON; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLES (SPION);

BIOLOGICAL ORGANS; COPOLYMERS; DYES; FLUORESCENCE; IRON OXIDES; METABOLISM; OPTICAL MICROSCOPY; POLYVINYL ALCOHOLS; SUPERPARAMAGNETISM;

NANOSTRUCTURED MATERIALS;

BIOMATERIAL; CARBOCYANINE; CYANINE DYE 3; MAGNETITE; NANOMATERIAL; POLYVINYL ALCOHOL;

ANIMAL; ANTIBODY SPECIFICITY; ARTICLE; CHEMISTRY; COMPARATIVE STUDY; EVALUATION; INTRAARTICULAR DRUG ADMINISTRATION; METABOLIC CLEARANCE RATE; SHEEP; TISSUE DISTRIBUTION; ULTRASTRUCTURE;

ANIMALS; CARBOCYANINES; COATED MATERIALS, BIOCOMPATIBLE; FERROSOFERRIC OXIDE; INJECTIONS, INTRA-ARTICULAR; METABOLIC CLEARANCE RATE; NANOSTRUCTURES; ORGAN SPECIFICITY; POLYVINYL ALCOHOL; SHEEP; TISSUE DISTRIBUTION;

EID: 33750054394     PISSN: 15334880     EISSN: None     Source Type: Journal    
DOI: 10.1166/jnn.2006.482     Document Type: Conference Paper

References (16)

1. A. K. Gupta and M. Gupta, Biomaterials 26, 3995 (2005).
2. T. Neuberger, B. Schöpf, H. Hofmann, M. Hofmann, and B. v. Rechenberg, J. Magn. Magn. Mater. 293, 483 (2005).
3. B. J. Dardzinski, V. J. Schmithorst, S. K. Holland, G. P. Boivin, T. Imagawa, S. Watanabe, J. M. Lewis, and R. Hirsch, Magn. Reson. Imaging 19, 1209 (2001).
4. G. M. Lanza, P. Winter, S. Caruthers, A. Schmeider, K. Crowder, A. Morawski, H. Zhang, M. J. Scott, and S. A. Wickline, Curr. Pharm. Biotechnol. 5, 495 (2004).
5. S. J. McLachlan, M. R. Morris, M. A. Lucas, R. A. Fisco, M. N. Eakins, D. R. Fowler, R. B. Scheetz, and A. Y. Olukotun, J. Magn. Reson. Imagina 4, 301 (1994).
6. D. C. F. Chan, D. Kirpotin, and P. A. Bunn, J. Magn. Magn. Mater. 122, 374 (1993).
7. A. Jordan, P. Wust, and R. Scholz, in Scientific and Clinical Applications of Magnetic Carriers, edited by U. Häfeli, W. Schütt, J. Teller, and M. Zborowski, Plenum Press, New York (1997), Vol. 569.
8. N. Beckmann, R. Falk, S. Zurbrügg, J. Dawson, and P. Engelhardt, Magn. Reson. Med. 49, 1047 (2003).
9. K. Schulze, A. Koch, B. Schöpf, A. Petri, B. Steitz, M. Chastellain, M. Hofmann, H. Hofmann, and B. v. Rechenberg, J. Magn. Magn. Mater. 293, 419 (2005).
10. S. O. B. G. Storm, T. Daemen, and D. D. Lasic, Adv. Drug Deliv. Rev. 17, 31 (1995).
11. R. Weissleder, D. D. Stark, B. L. Engelstad, B. R. Bacon, C. C. Compton, D. L. White, P. Jacobs, and J. Lewis, AJR Am. J. Roentgenol. 152, 167 (1989).
12. M. Chastellain, A. Petri, and H. Hofmann, J. Coll. Interf. Sci. 278, 353 (2004).
13. R. M. Cornell and U. Schwertmann, The Iron Oxides, VCH Verlagsgesellschaft, Weinheim, Germany (1996).
14. B. Schöpf, Doctoral Thesis, Equine Hospital, Vetsuisse-Faculty, University of Zurich (2004).
15. B. Schöpf, T. Neuberger, K. Schulze, A. Petri, M. Chastellain, M. Hofmann, H. Hofmann, and B. v. Rechenberg, J. Magn. Magn. Mater. 293, 411 (2005).
16. U. Pfeifer, in Allgemeine Pathologie, edited by A. Roessner, U. Pfeifer, and H. K. Müller-Hermelink, Elsevier GmbH. München (2004). Vol. 10, p. 31.