A new expert systems (SeDeM Diagram) for control batch powder formulation and preformulation drug products

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 64, Issue 3, 2006, Pages 351-359

  Pérez, Pilar ^a   Suñé Negre, Josep M ^a   Miñarro, Montserrat ^a   Roig, Manel ^a   Fuster, Roser ^a   García Montoya, Encarna ^a   Hernández, Carmen ^b   Ruhí, Ramón ^b   Ticó, Josep R ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b Bioiberica S A   (Spain)

Author keywords

Angle of repose ( ); Bulk density (Da); Direct compression (DC); Expert system; Flowability (t ); Formulation; Inter particle porosity (Ie); Particle size ( Pf); Preformulation; Tapped density (Dc)

Indexed keywords

GLUCOSAMINE;

ARTICLE; CONTROLLED RELEASE FORMULATION; DRUG FORMULATION; DRUG MECHANISM; EXPERT SYSTEM; POWDER; PREFORMULATION; REPRODUCIBILITY; TABLET COMPRESSION; TABLET FORMULATION;

CHEMISTRY, PHARMACEUTICAL; COMPRESSIVE STRENGTH; EXPERT SYSTEMS; GLUCOSAMINE; MODELS, CHEMICAL; POWDERS; QUALITY CONTROL; REPRODUCIBILITY OF RESULTS; TABLETS; TECHNOLOGY, PHARMACEUTICAL;

EID: 33750040538     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2006.06.008     Document Type: Article

References (13)

1. Suñé Negre J.M., Roig Carreras M., Fuster Garci{dotless}́a R., Hernández Pérez C., Ruhi{dotless}́ Roura R., Garci{dotless}́a Montoya E., Miñarro Carmona M., Pérez Lozano P., and Ticó Grau J.R. Nueva metodologi{dotless}́a de preformulación galénica para la caracterización de sustancias en relación a su viabilidad para la compresión: diagrama SeDeM. Cien. Technol. Pharm. 3 (2005) 125-136
2. European Pharmacopoeia, fifth ed., vol. 5.0, Council of Europe, Strasbourg (France), 2005, p. 2.9.15.
3. Font Quer P. Medicamenta. sixth ed. (1962), Editorial Labor, Barcelona pp. 340-341
4. Rubinstein M.H. Pharmaceutical Technology (Tableting Technology). first ed. (1987), Ellis Horwood Limited, Liverpool pp. 162
5. Córdoba Borrego M., Moreno Cerezo J.M., Córdoba Di{dotless}́az M., and Córdoba Di{dotless}́az D. Preformulación y desarrollo galénico de nuevas formulaciones por compresión directa con agentes hidrotrópicos. Ind. Farm. 4 (1996) 65-70
6. Torres Suárez A.I., and Camacho Sánchez M.A. Planteamiento de un programa de preformulación y formulación de comprimidos. Ind. Farm. 2 (1991) 85-92
7. Brittain H.G. On the Physical Characterization of Pharmaceutical Solids. Pharm. Technol. 1 (1997) 100-106
8. Wong L.W., and Pilpel N. The effect of particle shape on the mechanical properties of powders. Int. J. Pharm. 59 (1990) 145-154
9. Muñoz Rui{dotless}́z A., Muñoz Muñoz N., Monedero Perales M.C., Velasco Antequera M.V., and Jiménez Castellanos Ballesteros M.R. Determinación de la fluidez de sólidos a granel. Métodos (I). Ind. Farm. 1 (1993) 49-55
10. European Pharmacopoeia, fifth ed., vol. 5.0, Council of Europe, Strasbourg (France), 2005, p. 2.9.16; vol. 5.1, p. 2.9.36.
11. European Pharmacopoeia, fifth ed., vol. 5.1, Council of Europe, Strasbourg (France), 2005, p. 2.2.32.
12. European Pharmacopoeia, fifth ed., vol. 5.1, Council of Europe, Strasbourg (France), 2005, p. 2.9.38.
13. Handbook of Pharmaceutical Excipients. fifth ed. (2006), American Pharmaceutical Association, Pharmaceutical Press, London