Assessing the predictive accuracy of hMLH1 and hMSH2 mutation probability models

Journal of Genetic Counseling

Volumn 15, Issue 5, 2006, Pages 339-347

  Jasperson, Kory W ^a   Lowstuter, Katrina ^a   Weitzel, Jeffrey N ^a  

^a CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

hMLH1 and hMSH2 mismatch repair genes; HNPCC; Lynch syndrome; Mutation probability models

Indexed keywords

PROTEIN MLH1; PROTEIN MSH2;

ARTICLE; COLON CANCER; COLORECTAL CANCER; DIAGNOSTIC ACCURACY; DISEASE PREDISPOSITION; EVALUATION; FAMILY ASSESSMENT; GENE; GENE MUTATION; GENETIC ANALYSIS; GENETIC RISK; GENETIC SCREENING; GERM LINE; HMLH1 GENE; HMSH2 GENE; HUMAN; MAJOR CLINICAL STUDY; MUTATION RATE; MYRIAD GENETICS LABORATORY PREVALENCE TABLE; PREDICTION; PREDICTIVE VALIDITY; PREVALENCE; PROBABILITY; SENSITIVITY AND SPECIFICITY; STATISTICAL MODEL; WIJNEN PRE TEST PROBABILITY MODEL;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CARRIER PROTEINS; HUMANS; MODELS, GENETIC; MUTATION; MUTS HOMOLOG 2 PROTEIN; NUCLEAR PROTEINS; PROBABILITY;

EID: 33750001129     PISSN: 10597700     EISSN: 15733599     Source Type: Journal    
DOI: 10.1007/s10897-006-9035-6     Document Type: Article

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