Prediction of the solubility of 6APA in aqueous phase and optimum control scheme for batch crystallization process through pH variation

Korean Journal of Chemical Engineering

Volumn 19, Issue 6, 2002, Pages 992-995

  ZareNezhad, Bahman ^a  

^a IRAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Iran)

Author keywords

6APA solubility; Batch crystallization; Crystal size distribution; Optimum pH profile

Indexed keywords

EID: 33749864185     PISSN: 02561115     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02707222     Document Type: Article

References (8)

1. Brown, M. G. and Rousseau, R. W, "Effect of Sodium Hydroxide on the Solubilities of L-isoleucine, L-leucine and L-valine", Biotechnology Progress, 10,253 (1994).
2. ICI Technical Boultin, London, England (1995). Mwangi, S, "Chemistry Lab. Report", UMIST, Manchester, England (1994).
3. Patrickios, C. S, Herder, W. R, Abbot, N. L. and Haton, T. A., "Diblock, ABC Triblock and Random Methacrylic Polyampholytes: Synthesis by Group Transfer Polymerization and Solution Behaviour, Macromoleades, 27,115 (1993).
4. Randolph, A. D. and Larson, M. A, "Theory of Particulate Processes", Academic Press, New York (1971).
5. Tavare, N. S. and Garside, J, "Simultaneous Estimation of Crystal Nu- cleation and Growth Kinetics from Batch Experiments", Chem. Eng. Res. Des., 64,109 (1986).
6. Tewari, Y. B. and Goldberg, R. N, "Solubility of Amino Acids in Pure Solvent Systems", Biophys. Chem., 29,245 (1988).
7. ZareNezhad, B, "Determination of 6APA Crystallization Kinetics", Research Report, IUST, Tehran, Iran (2001).
8. Zhu, Y, Evans, L. B. and Chen, C, "Representation of Phase Equilibrium Behaviour of Antibiotics", Biotechnol. Prog, 6,266 (1990).