An inhibitor of serine proteases, neuroserpin, acts as a neuroprotective agent in a mouse model of neurodegenerative disease

Journal of Neuroscience

Volumn 26, Issue 41, 2006, Pages 10614-10619

  Simonin, Yannick ^a   Charron, Yves ^a   Sonderegger, Peter ^b   Vassalli, Jean Dominique ^a   Kato, Ann C ^a,c  

^a UNIVERSITY OF GENEVA   (Switzerland)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c Centre Médical Universitaire   (Switzerland)

Author keywords

Axon; Motoneurons; Neuroserpin; Plasminogen activator; pmn mice; Spinal cord

Indexed keywords

NEUROPROTECTIVE AGENT; NEUROSERPIN; SERINE PROTEINASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; DEGENERATIVE DISEASE; ENZYME ACTIVITY; LOCOMOTION; MOTOR NEURON DISEASE; MOTOR NEUROPATHY; MOUSE; NERVE FIBER DEGENERATION; NONHUMAN; PRIORITY JOURNAL; SCIATIC NERVE; TRANSGENIC MOUSE;

ANIMALS; DISEASE MODELS, ANIMAL; MICE; MICE, TRANSGENIC; NEURODEGENERATIVE DISEASES; NEUROPEPTIDES; NEUROPROTECTIVE AGENTS; SERINE ENDOPEPTIDASES; SERINE PROTEINASE INHIBITORS; SERPINS;

EID: 33749855725     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3582-06.2006     Document Type: Article

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