Bombesin receptors as a novel anti-anxiety therapeutic target: BB 1 receptor actions on anxiety through alterations of serotonin activity

Journal of Neuroscience

Volumn 26, Issue 41, 2006, Pages 10387-10396

  Merali, Zul ^a   Bédard, Tania ^a   Andrews, Nick ^b   Davis, Ben ^c   McKnight, Alexander T ^d   Gonzalez, M Isabel ^e   Pritchard, Martyn ^f   Kent, Pam ^a   Anisman, Hymie ^g  

^a UNIVERSITY OF OTTAWA   (Canada)

^b MERCK RESEARCH LABORATORIES   (United States)

^c BioWisdom Ltd   (United Kingdom)

^d ATMcK Consulting   (United Kingdom)

^e GLAXOSMITHKLINE   (United Kingdom)

^f Cambridge BioTechnology   (United Kingdom)

^g CARLETON UNIVERSITY   (Canada)

Author keywords

5 hydroxytryptamine; Anxiety; Dorsal raph nucleus; Fear potentiated startle; Guinea pig pup vocalizations; Neuromedin B; Social interaction

Indexed keywords

3 (1H INDOL 3 YL) N [ 5 METHOXYPYRIDIN 2 YL)CYCLOHEXYLMETHYL] 2 METHYL 2 [ 3 (NITROPHENYL)UREIDO]PROPIONAMIDE; ANXIOLYTIC AGENT; BOMBESIN ANTAGONIST; BOMBESIN RECEPTOR; SEROTONIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANXIETY; ARTICLE; CONTROLLED STUDY; DORSAL RAPHE NUCLEUS; DOSE RESPONSE; FEAR; GUINEA PIG; IN VIVO STUDY; LATENT PERIOD; NERVE ENDING; NONHUMAN; PRIORITY JOURNAL; RAT; SOCIAL INTERACTION; VOCALIZATION;

ANIMALS; ANTI-ANXIETY AGENTS; ANXIETY; DRUG DELIVERY SYSTEMS; FEMALE; GUINEA PIGS; INDOLES; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, BOMBESIN; SEROTONIN;

EID: 33749848054     PISSN: 02706474     EISSN: 02706474     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1219-06.2006     Document Type: Article

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