Role of endothelin-1 and its receptors on hypertrophy or proliferation of cultured cardial cells

Acta Academiae Medicinae Sinicae

Volumn 28, Issue 4, 2006, Pages 520-523

  You, Hong Wen ^a   Chen, Xi ^a,b   You, Hong Jie ^a,c   Zhang, Yu Qing ^a,b   Cai, Yan ^a,b   Liu, Guo Zhang ^a,b  

^a SHANDONG PROVINCIAL HOSPITAL AFFILIATED TO SHANDONG UNIVERSITY   (China)

^b FUWAI HOSPITAL   (China)

^c CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Cardiac fibroblast; Cardiomyocyte; Endothelin receptor; Endothelin 1

Indexed keywords

ATRIAL NATRIURETIC FACTOR; CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); ENDOTHELIN 1; ENDOTHELIN RECEPTOR; ENDOTHELIN RECEPTOR ANTAGONIST; LEUCINE; MESSENGER RNA; N (2,6 DIMETHYLPIPERIDINOCARBONYL) 4 METHYLLEUCYL DEXTRO (1 METHOXYCARBONYLTRYPTOPHANYL) DEXTRO NORLEUCINE; TRYPSIN;

ARTICLE; CELL CULTURE; CELL ISOLATION; CELL PROLIFERATION; CONTROLLED STUDY; DNA DETERMINATION; DNA SYNTHESIS; FIBROBLAST; HEART HYPERTROPHY; HEART MUSCLE CELL; PROTEIN CONTENT; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; ANIMALS, NEWBORN; ATRIAL NATRIURETIC FACTOR; CELL PROLIFERATION; CELLS, CULTURED; ENDOTHELIN-1; FIBROBLASTS; HYPERTROPHY; MYOCYTES, CARDIAC; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, ENDOTHELIN A; RNA, MESSENGER;

EID: 33749841621     PISSN: 1000503X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. 2+ modulation. Circ Res, 1996, 78:302-311.
2. Kedzierski RM, Grayburn PA, Kisanuki YY, et al. Cardiomyocyte-specific endothelin A receptor knockout mice have normal cardiac function and an unaltered hypertrophic response to angiotensin II and isoproterenol. Mol Cell Biol, 2003, 23 (22): 8226-8232.
3. Hafizi S, Wharton J, Cheste AH, et al. Profibrotic effects of endothelin-1 via the ETA receptor in cultured human cardiac fibroblasts. Cell Physiol Biochem, 2004, 14(4-6):285-292.
4. Simpson P, Mc Grath A, Savion S. Myocyte hypert rophy in neonatal rat heart cultures and its regulation by serum and by catecholamines. Circ Res, 1982, 51(6):787-801.
5. Chinese source. 2004, 12(2):161-164.
6. Smith JA, Ausubel FM, Brent R, et al. Short protocols in molecular biology. 3rd ed. New York: John Wiley & Sons, Inc., 1995. 402.
7. Lee YJ, Shin SJ, Tan MS. Increased renal atrial natriuretic peptide synthesis in rats with deoxycorticosterone acetate-salt treatment Am J Physiol, 1996, 271:F779-F789.
8. Turner NA, O'regan DJ, Ball SG, et al. Endothelin-1 is an essential co-factor for beta2-adrenergic receptor-induced proliferation of human cardiac fibroblasts. FEBS Lett, 2004, 576(1-2):156-160.
9. Rothermund L, Vetter R, Dieterich M, et al. Endothelin-A receptor blockade prevents left ventricular hypertrophy and dysfunction in salt-sensitive experimental hypertension. Circulation, 2002, 106(18):2305-2308.