Giardia duodenalis: Analysis of secreted proteases upon trophozoite-epithelial cell interaction in vitro

Memorias do Instituto Oswaldo Cruz

Volumn 101, Issue 6, 2006, Pages 693-696

  Rodríguez Fuentes, Guadalupe Beatriz ^a   Cedillo Rivera, Roberto ^b   Fonseca Liñán, Rocío ^c   Argüello García, Raúl ^c   Muñoz, Onofre ^a   Ortega Pierres, Guadalupe ^c   Yépez Mulia, Lilián ^a  

^a HOSPITAL DE PEDIATRÍA   (Mexico)

^b INSTITUTO MEXICANO DEL SEGURO SOCIAL   (Mexico)

^c DEPARTAMENTO DE FÍSICA   (Mexico)

Author keywords

Adhesion; Giardia duodenalis; Protease secretion

Indexed keywords

GIARDIA INTESTINALIS;

EID: 33749664379     PISSN: 00740276     EISSN: 16788060     Source Type: Journal    
DOI: 10.1590/S0074-02762006000600020     Document Type: Article

References (19)

1. Adam RD 1991. The biology of Giardia spp. Microbiol Rev 55: 706-732.
2. Argüello-García R, Cruz-Soto M, Romero-Montoya L, Ortega-Pierres MG 2004. Variability and variation in drug susceptibility among Giardia duodenalis isolates and clones exposed to 5-nitroimidazoles and bencimidazoles in vitro. J Antimicrob Chemother 54: 711-721.
3. Arroyo R, Alderete JF 1995. The mechanism and molecules involved in cytoadherence and pathogenesis of Trichomonas vaginalis. Parasitol Today 11: 70-74.
4. Bermúdez-Cruz RM, Ortega-Pierres G, Ceja V, Coral-Vázquez R, Fonseca R, Cervantes L, Sánchez A, Depardon F, Newport G, Montañez C 2004. A 63 kDa VSP9B10A-like protein expressed in a C-8 Giardia duodenalis Mexican clone. Arch Med Res 35: 199-208.
5. Beynon RJ, Bond JS 1994. Proteolytic Enzymes. A Practical Approach, IRL Press, Oxford.
6. Chávez B, González-Mariscal L, Cedillo-Rivera R, Martínez-Palomo A 1995. Giardia lamblia: in vitro cytopathic effect of human symptomatic and asymptomatic isolates. Exp Parasitol 80: 133-137.
7. Coradi ST, Guimarães S 2006. Giardia duodenalis: protein substrates degradation by trophozoite proteases. Parasitol Res 99: 131-136.
8. Feely DE, Dyer JK 1987. Localization of acid phosphatase activity in Giardia lamblia and Giardia muris trophozoites. J Protozool 34: 80-83.
9. García-Rivera G, Rodríguez MA, Ocadiz M, Martínez-López M, Arroyo R, González-Robles A, Orozco E 1999. Entamoeba hystolytica: a novel cysteine protease and an adhesin form the 112 kDa surface protein. Mol Microbiol 33: 556-568.
10. Hare DF, Jarroll EL, Lindmark DG 1989. Giardia lamblia: characterization of proteinase activity in trophozoites. Exp Parasitol 68: 168-175.
11. Jiménez JC, Fontaine J, Grzych JM, Dei-Cas E, Capron M 2004. Systemic and mucosal responses to oral administration of excretory and secretory antigens from Giardia duodenalis. Clin Diag Lab Immunol 11: 152-160.
12. Jiménez JC, Uzcanga G, Zambrano A, Di Prisco M, Lymch NR 2000. Identification and partial characterization of excretory/secretory products with proteolytic activity in Giardia duodenalis. J Parasitol 86: 662-667.
13. Knaippe F 1990. Giardia lamblia attachment to biological and inert sustrates. Micr Electr Biol Cel 14: 35-42.
14. McCabe RE, Yu GSM, Conteas C, Morril PR, McMorrow B 1991. In vitro model of attachment of Giardia intestinalis trophozoites to IEC6 cells, an intestinal cell line. Antimicrob Agents Chemother 35: 29-35.
15. Paget TA, James SL 1994. The mucolytic activity of polyamines and mucosal invasion. Biochem Soc Trans 22: 394S-398S.
16. Parenti DM 1989. Characterization of a thiol proteinase in Giardia lamblia. J Infect Dis 106: 1076-1080.
17. Pegado MGF, Souza W 1994. Role of surface components in the process of interaction of Giardia duodenalis with epithelial cells in vitro. Parasitol Res 80: 320-325.
18. Werries E, Franz A, Hippe H, Acil Y 1991. Purification and substrate specificity of two cysteine proteinases from Giardia lamblia. J Protozool 38: 378-383.
19. Williams AG, Coombs HG 1995. Multiple protease activities in Giardia intestinalis trophozoites. Int J Parasitol 25: 771-778.