Thermal inactivation of ricin using infant formula as a food matrix

Journal of Agricultural and Food Chemistry

Volumn 54, Issue 19, 2006, Pages 7300-7304

  Jackson, Lauren S ^a   Tolleson, William H ^b   Chirtel, Stuart J ^a  

^a CENTER FOR DRUG EVALUATION AND RESEARCH   (United States)

^b NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

Author keywords

Cytotoxicity; Heat; Infant formula; Ricin; Stability; Thermal processing

Indexed keywords

RICIN;

ANIMAL; ARTICLE; ARTIFICIAL MILK; CELL DEATH; CELL LINE; CHEMISTRY; DRUG EFFECT; DRUG STABILITY; ENZYME LINKED IMMUNOSORBENT ASSAY; HEAT; MACROPHAGE; MILK; MOUSE; SOYBEAN;

ANIMALS; CELL DEATH; CELL LINE; DRUG STABILITY; ENZYME-LINKED IMMUNOSORBENT ASSAY; HEAT; INFANT FORMULA; MACROPHAGES; MICE; MILK; RICIN; SOYBEANS;

RICINUS COMMUNIS;

EID: 33749656178     PISSN: 00218561     EISSN: None     Source Type: Journal    
DOI: 10.1021/jf061199n     Document Type: Article

References (24)

1. Chen, G. Q.; He, X.; McKeon, T. A. A simple and sensitive assay for distinguishing the expression of ricin and Ricinus communis agglutinin genes in developing castor seed (R. communis L.). J. Agric. Food Chem. 2005, 53, 2358-2361.
2. Fredriksson, S.-A.; Hulst, A. G.; Artursson, E.; de Jong, A. L.; Nilsson, C.; van Baar, B. L. M. Forensic identification of neat ricin and of ricin from crude castor bean extracts by mass spectrometry. Anal. Chem. 2005, 77, 1545-1555.
3. Bradberry, S. M.; Dickers, K. J.; Rice, P.; Griffiths, G. D.; Vale, J. A. Ricin poisoning. Toxicol. Rev. 2003, 22, 65-70.
4. Frenoy, J.-P.; Tran, A.-T.; Bourrillon, R. Structure and stability of Ricinus communis haemagglutinin. Biochem. J. 1986, 240, 227-231.
5. Audi, J.; Belson, M.; Patel, M.; Schier, J.; Osterloh, J. Ricin poisoning. A comprehensive review. JAMA, J. Am. Med. Assoc. 2005, 294, 2342-2351.
6. Olsnes, S.; Fernandez-Puentes, C.; Carrasco, L.; Vazquez, D. Ribosome inactivation by the toxic lectins abrin and ricin. Kinetics of the enzymic activity of the toxin A-chains. Eur. J. Biochem. 1975, 60, 281-288.
7. Eiklid, K.; Olsnes, S.; Pihl, A. Entry of lethal doses of abrin, ricin and modeccin into the cytosol of HeLa cells. Exp. Cell Res. 1980, 126, 321-326.
8. Franz, D. R.; Jaax, N. K. Ricin Toxin. In Medical Aspects of Chemical and Biological Warfare; Sidell, F. R., Takafuji, F. T., Franz, D. R., Eds.; Office of the Surgeon General, Bordon Institute, Walter Reed Army Medical Center: Washington, DC, 1997; pp 631-642.
9. Winder, C. Toxicity of ricin. J. Toxicol., Toxin Rev. 2004, 23, 97-103.
10. Lord, M. J.; Jolliffe, N. A.; Marsden, C. J.; Pateman, C. S. C.; Smith, D. C.; Spooner, R. A.; Watson, P. D.; Roberts, L. M. Ricin. Mechanisms of cytotoxicity. Toxicol. Rev. 2003, 22, 53-64.
11. Crompton, R.; Gall, D. Georgi Markov: death in a pellet. Med.-Leg. J. 1980, 48, 51-62.
12. Challoner, K. R.; McCarron, M. M. Castor bean intoxication: review of reported cases. Ann. Emerg. Med. 1990, 19, 1177-1183.
13. Jenkins, F. P. Allergenic and toxic components of castor bean meal: Review of the literature and studies of the inactivation of these components. J. Sci. Food Agric. 1963, 14, 773-780.
14. Okorie, A. U.; Anugwa, F. O. I. The feeding value of roasted castor bean (Ricinus communis) to growing chicks. Plant Foods Human Nutr. 1987, 37, 97-102.
15. Battelli, M. G.; Musiani, S.; Monti, B.; Buonamici, L.; Sparapani, M; Contestabile, A.; Stirpe, F. Ricin toxicity to microglial and monocytic cells. Neurochem. Int. 2001, 39, 83-93.
16. Battelli, M. G. Cytotoxicity and toxicity to animals and humans of ribosome-inactivating proteins. Mini-Rev. Med. Chem. 2004, 4, 513-521.
17. Hassoun, E. A.; Wang, X. Time- and concentration-dependent production of superoxide anion, nitric oxide, DNA damage and cellular death by ricin in J774A. 1 macrophage cells. J. Biochem. Mol. Toxicol. 1999, 13, 179-185.
18. Higuchi, S.; Tamara, T.; Oda, T. Cross-talk between the pathways leading to the induction of apoptosis and the secretion of tumor necrosis factor-alpha in ricin-treated RAW 264.7 cells. J. Biochem. (Tokyo) 2003, 134, 927-933.
19. Layton, L. L. Castorbean allergens in tissues of catfish reared on a diet containing castorbean pomace. J. Sci. Food Agric. 1977, 28, 399-404.
20. Gardner, H. K., Jr.; D'Aquin, E. L.; Koltun, S. P.; McCourtney, E. J.; Vix, H. L. E.; Gastrock, E. A. Detoxification and deallergenization of castor beans. J. Am. Oil Chem. Soc. 1960, 37, 142-148.
21. Losikoff, M. E. Establishment of a heat inactivation curve for Clostridium botulinum 62A toxin in beef broth. Appl. Environ. Microbiol. 1978, 36, 386-388.
22. Denny, C. B.; Humber, J. Y.; Bohrer, C. W. Effect of toxin concentration on the heat inactivation of Staphylococcal enterotoxin A in beef bouillon and in phosphate buffer. Appl. Microbiol. 1971, 21, 1064-1066.
23. Hilker, J. S.; Heilman, W. R.; Tan, P. L.; Denny, C. B.; Bohrer, C. W. Heat inactivation of enterotoxin A from Staphylococcus aureus in veronal buffer. Appl. Microbiol. 1968, 16, 308-310.
24. Read, R. B., Jr.; Bradshaw, J. G. Thermal inactivation of Staphylococcal enterotoxin B in Veronal buffer. Appl. Microbiol. 1966, 14, 130-132.