Principal component, Varimax rotation and cost analysis of volume effects in rectal bleeding in patients treated with 3D-CRT for prostate cancer

Physics in Medicine and Biology

Volumn 51, Issue 20, 2006, Pages 5105-5123

  Bauer, J D ^a,b   Jackson, Andrew ^a   Skwarchuk, Mark ^a,c   Zelefsky, Michael ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b LAWRENCE LIVERMORE NATIONAL LABORATORY   (United States)

^c KALISPELL REGIONAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOSE VOLUME COMBINATIONS; INTERPRETABILITY; RECTAL BLEEDING; TREATMENT PLANNING;

CATHODE RAY TUBES; COST BENEFIT ANALYSIS; DEGREES OF FREEDOM (MECHANICS); ONCOLOGY; PRINCIPAL COMPONENT ANALYSIS; RADIOTHERAPY;

PATIENT TREATMENT;

ARTICLE; COMPUTER ASSISTED RADIOTHERAPY; COST BENEFIT ANALYSIS; COVARIANCE; FALSE POSITIVE RESULT; HISTOGRAM; HUMAN; LOGISTIC REGRESSION ANALYSIS; MAJOR CLINICAL STUDY; MATHEMATICAL MODEL; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; PROSTATE CANCER; RADIATION DOSE; RADIATION INJURY; RECEIVER OPERATING CHARACTERISTIC; RECTUM HEMORRHAGE; TREATMENT PLANNING; TUMOR VOLUME; VARIMAX ROTATION;

GASTROINTESTINAL HEMORRHAGE; HUMANS; MALE; PRINCIPAL COMPONENT ANALYSIS; PROSTATIC NEOPLASMS; RADIATION INJURIES; RADIOTHERAPY PLANNING, COMPUTER-ASSISTED; RADIOTHERAPY, CONFORMAL; RECTUM; RISK ASSESSMENT; RISK FACTORS;

EID: 33749648136     PISSN: 00319155     EISSN: 13616560     Source Type: Journal    
DOI: 10.1088/0031-9155/51/20/003     Document Type: Article

References (16)

1. Bauer J D, Jackson A, Skwarchuk M, Zelefsky M, Leibel S and Ling C 2004 Principal component analysis as applied to volume effects in treatment outcomes for patients with prostate cancer treated with 3D-CRT AAPM 46th Ann. Mtg. (Pittsburgh, PA, June 2004) Med. Phys. 31 1910
2. Bradley A P 1997 The use of the area under the ROC curve in the evaluation of machine learning algorithms Pattern Recognit. 30 1145-59
3. Dawson L A, Biersack M, Lockwood G, Math M, Eisbruch A, Lawrence T S and Ten Haken R K 2005 Use of principal component analysis to evaluate the partial organ tolerance of normal tissues to radiation Int. J. Radiat. Oncol. Biol. Phys. 62 829-37
4. Hand D J and Till R J 2001 A simple generalization of the area under the ROC curve for multiple class classification problems Mach. Learn. 45 171-86
5. Hanley J A and McNeil B 1982 The meaning and use of the area under a receiver operating characteristic (ROC) curve Radiology 143 29-36
6. Hanley J A and McNeil B 1983 The method of comparing the areas under receiver operating characteristic curves derived from the same cases Radiology 148 839-43
7. Harman H H 1970 Modern Factor Analysis 2nd revised edn (Chicago, IL: University of Chicago Press)
8. Jackson A et al 2001 Late rectal bleeding after conformal radiotherapy of prostate cancer: II. Volume effects and dose-volume histograms Int. J. Radiat. Oncol. Biol. Phys. 49 685-98
9. Joliffe I T 1995 Rotation of principal components: choice of normalization constraints J. Appl. Stat. 22 29-35
10. Kleinbaum D G 2004 Logistic Regression: A Self-Learning Text (New York: Springer)
11. Krzanowski W J 2000 Principles of Multivariate Analysis: A User's Perspective revised edn (Oxford: Oxford University Press)
12. Lawton C A et al 1991 Long-term treatment sequelae following external beam irradiation for adenocarcinoma of the prostate: analysis of RTOG studies 7506 & 7706 Int. J. Radiat. Oncol. Biol. Phys. 21 935-9
13. Le C T 2003 Introductory Biostatistics (Hoboken, NJ: Wiley)
14. McCullagh P and Nelder J A 1989 Generalized Linear Models 2nd edn (London: Chapman and Hall)
15. Prentice R L and Pyke R 1979 Logistic disease incidence models and case-control studies Biometrika 66 403-11
16. Skwarchuk M W, Jackson A, Zelefsky M J, Venkatraman E S, Cowen D M, Levegrun S, Burman C M, Fuks Z, Leibel S A and Ling C C 2000 Late rectal toxicity after conformal radiotherapy of prostate cancer: I. Multivariate analysis and dose response Int. J. Radiat. Oncol. Biol. Phys. 47 103-13