Importance of bile acids for novel oral absorption system containing polyamines to improve intestinal absorption

Journal of Controlled Release

Volumn 115, Issue 2, 2006, Pages 130-133

  Miyake, Masateru ^a   Minami, Takanori ^b   Toguchi, Hajime ^a   Odomi, Masaaki ^a   Ogawara, Ken ichi ^c   Higaki, Kazutaka ^c   Kimura, Toshikiro ^c  

^a OTSUKA PHARMACEUTICAL CO LTD   (Japan)

^b Tokushima Research Institute   (Japan)

^c OKAYAMA UNIVERSITY   (Japan)

Author keywords

Beagle dog; Bile acid; Bile duct ligated rat; Intestinal absorption; Polyamine

Indexed keywords

BEAGLE DOG; BILE ACIDS; BILE DUCT LIGATED (BDL) RAT; INTESTINAL ABSORPTION; SODIUM TAUROCHOLATE (STC);

ABSORPTION; AMINES; BIOLOGICAL ORGANS; DRUG PRODUCTS; SODIUM COMPOUNDS;

ORGANIC ACIDS;

ACETONITRILE DERIVATIVE; BILE ACID; OPC 12853; POLYAMINE DERIVATIVE; REBAMIPIDE; SPERMINE; TAUROCHOLIC ACID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BILE DUCT LIGATION; CONTROLLED STUDY; DOG; DRUG ABSORPTION; DRUG FORMULATION; DRUG SOLUBILITY; INTESTINE ABSORPTION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

ALANINE; ANIMALS; AREA UNDER CURVE; BILE ACIDS AND SALTS; BILE DUCTS; BIOGENIC POLYAMINES; DOGS; INTESTINAL ABSORPTION; LIGATION; MALE; QUINOLONES; RATS; RATS, SPRAGUE-DAWLEY; SPERMINE; TAUROCHOLIC ACID;

EID: 33749548071     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2006.07.015     Document Type: Article

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