Inhibition of P-glycoprotein-mediated transport by terpenoids contained in herbal medicines and natural products

Food and Chemical Toxicology

Volumn 44, Issue 12, 2006, Pages 2033-2039

  Yoshida, Naoko ^a   Koizumi, Mariya ^a   Adachi, Isao ^a   Kawakami, Junichi ^b  

^a TOYAMA UNIVERSITY HOSPITAL   (Japan)

^b HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Abietic acid; Citronellal; Drug interaction; Glycyrrhetic acid; P glycoprotein; Terpenoids

Indexed keywords

ABIETIC ACID; BETA PINENE; CITRONELLAL; CITRONELLOL; CUCURBITACIN GLYCOSIDE; DIGOXIN; GLYCOPROTEIN P; GLYCYRRHETINIC ACID; TERPENOID DERIVATIVE; TERPINENE; TERPINOLENE; VERAPAMIL;

ARTICLE; CONTROLLED STUDY; GENETIC TRANSFECTION; HERBAL MEDICINE; HUMAN; HUMAN CELL; MEMBRANE TRANSPORT; PROTEIN INTERACTION;

ANIMALS; BIOLOGICAL TRANSPORT; CACO-2 CELLS; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ANTAGONISM; DRUG COMBINATIONS; HUMANS; INTESTINAL ABSORPTION; LLC-PK1 CELLS; P-GLYCOPROTEIN; PLANT PREPARATIONS; SWINE; TERPENES;

EID: 33749539429     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2006.07.003     Document Type: Article

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