메뉴 건너뛰기




Volumn 20, Issue 6, 2006, Pages 546-551

Panax ginseng C.A. Mayer G115 modulates pro-inflammatory cytokine production in mice throughout the increase of macrophage toll-like receptor 4 expression during physical stress

Author keywords

Cytokines; Ginseng; Stress; TLRs

Indexed keywords

GINSENG EXTRACT; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; MESSENGER RNA; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA;

EID: 33749528498     PISSN: 08891591     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbi.2005.11.007     Document Type: Article
Times cited : (42)

References (43)
  • 1
    • 0037177825 scopus 로고    scopus 로고
    • Novel signal transduction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4
    • Asea A., Rehli M., Kabingu E., Boch J.A., Bare O., Auron P.E., Stevenson M.A., and Calderwood S.K. Novel signal transduction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4. J. Biol. Chem. 17 (2002) 15028-15034
    • (2002) J. Biol. Chem. , vol.17 , pp. 15028-15034
    • Asea, A.1    Rehli, M.2    Kabingu, E.3    Boch, J.A.4    Bare, O.5    Auron, P.E.6    Stevenson, M.A.7    Calderwood, S.K.8
  • 2
    • 0344549853 scopus 로고    scopus 로고
    • Ginseng pharmacology: multiple constituents and multiple actions
    • Attele A.S., Wu J.A., and Yunan C.S. Ginseng pharmacology: multiple constituents and multiple actions. Biochem. Pharmacol. 11 (1999) 1685-1693
    • (1999) Biochem. Pharmacol. , vol.11 , pp. 1685-1693
    • Attele, A.S.1    Wu, J.A.2    Yunan, C.S.3
  • 3
    • 0042234050 scopus 로고    scopus 로고
    • The inflammatory response is an integral part of the stress response: Implications for atherosclerosis, insulin resistance, type II diabetes and metabolic syndrome X
    • Black P.H. The inflammatory response is an integral part of the stress response: Implications for atherosclerosis, insulin resistance, type II diabetes and metabolic syndrome X. Brain Behav. Immun. 5 (2003) 350-364
    • (2003) Brain Behav. Immun. , vol.5 , pp. 350-364
    • Black, P.H.1
  • 4
    • 0036911319 scopus 로고    scopus 로고
    • Stress and the inflammatory response: a review of neurogenic inflammation
    • Black P.H. Stress and the inflammatory response: a review of neurogenic inflammation. Brain Behav. Immun. 6 (2002) 622-653
    • (2002) Brain Behav. Immun. , vol.6 , pp. 622-653
    • Black, P.H.1
  • 5
    • 0033861419 scopus 로고    scopus 로고
    • The interleukin-1 receptor/Toll-like receptor superfamily: signal generators for pro-inflammatory interleukins and microbial products
    • Bowie A., and O'Neill L.A. The interleukin-1 receptor/Toll-like receptor superfamily: signal generators for pro-inflammatory interleukins and microbial products. J. Leukoc. Biol. 4 (2000) 508-514
    • (2000) J. Leukoc. Biol. , vol.4 , pp. 508-514
    • Bowie, A.1    O'Neill, L.A.2
  • 6
    • 0037215211 scopus 로고    scopus 로고
    • Role of extracellular HSP72 in acute stress induced potentiation of innate immunity in active rats
    • Campisi J., and Fleshner M. Role of extracellular HSP72 in acute stress induced potentiation of innate immunity in active rats. J. Appl. Physiol. 94 (2003) 43-52
    • (2003) J. Appl. Physiol. , vol.94 , pp. 43-52
    • Campisi, J.1    Fleshner, M.2
  • 7
    • 0033559496 scopus 로고    scopus 로고
    • Human 60 Kda heat shock protein: a danger signal to the innate immune system
    • Chen W., Syldath U., Bellmann K., Burkart V., and Kolb H. Human 60 Kda heat shock protein: a danger signal to the innate immune system. J. Immunol. 162 (1999) 3212-3219
    • (1999) J. Immunol. , vol.162 , pp. 3212-3219
    • Chen, W.1    Syldath, U.2    Bellmann, K.3    Burkart, V.4    Kolb, H.5
  • 8
    • 0036175621 scopus 로고    scopus 로고
    • Hyperthermic stress stimulates the association of both constitutive and inducible isoforms of 70 kDa heat shock protein with rat liver glucocorticoid receptor
    • Cvoro A., and Matic G. Hyperthermic stress stimulates the association of both constitutive and inducible isoforms of 70 kDa heat shock protein with rat liver glucocorticoid receptor. Int. J. Biochem. Cell Biol. 34 (2002) 279-285
    • (2002) Int. J. Biochem. Cell Biol. , vol.34 , pp. 279-285
    • Cvoro, A.1    Matic, G.2
  • 9
    • 0036920021 scopus 로고    scopus 로고
    • Stress-induced augmentation of immune function-the role of stress hormones, leukocyte trafficking, and cytokines
    • Dhabhar F.S. Stress-induced augmentation of immune function-the role of stress hormones, leukocyte trafficking, and cytokines. Brain Behav. Immun. 6 (2002) 785-798
    • (2002) Brain Behav. Immun. , vol.6 , pp. 785-798
    • Dhabhar, F.S.1
  • 10
    • 0038542113 scopus 로고    scopus 로고
    • Stress, leukocyte trafficking, and the augmentation of skin immune function
    • Dhabhar F.S. Stress, leukocyte trafficking, and the augmentation of skin immune function. Ann. N Y. Acad. Sci. 992 (2003) 205-217
    • (2003) Ann. N Y. Acad. Sci. , vol.992 , pp. 205-217
    • Dhabhar, F.S.1
  • 11
    • 0029880782 scopus 로고    scopus 로고
    • Stress-induced enhancement of antigen-specific cell-mediated immunity
    • Dhabhar F.S., and McEwen B.S. Stress-induced enhancement of antigen-specific cell-mediated immunity. J. Immunol. 7 (1996) 2608-2615
    • (1996) J. Immunol. , vol.7 , pp. 2608-2615
    • Dhabhar, F.S.1    McEwen, B.S.2
  • 12
    • 0037065909 scopus 로고    scopus 로고
    • Inflammatory response after open heart surgery: release of heat-shock protein 70 and signaling through toll-like receptor-4
    • Dybdahl B., Wahba A., Lien E., Flo TH., Waage A., Qureshi N., Sellevold O.F., Espevik T., and Sundan A. Inflammatory response after open heart surgery: release of heat-shock protein 70 and signaling through toll-like receptor-4. Circulation 6 (2002) 685-690
    • (2002) Circulation , vol.6 , pp. 685-690
    • Dybdahl, B.1    Wahba, A.2    Lien, E.3    Flo, TH.4    Waage, A.5    Qureshi, N.6    Sellevold, O.F.7    Espevik, T.8    Sundan, A.9
  • 13
    • 22244486324 scopus 로고    scopus 로고
    • Physical activity and stress resistance: sympathetic nervous system adaptations prevent stress-induced immunosuppression
    • Fleshner M. Physical activity and stress resistance: sympathetic nervous system adaptations prevent stress-induced immunosuppression. Exerc. Sport. Sci. Rev. 33 (2005) 120-126
    • (2005) Exerc. Sport. Sci. Rev. , vol.33 , pp. 120-126
    • Fleshner, M.1
  • 14
    • 3042636977 scopus 로고    scopus 로고
    • Cat exposure induces both intra- and extracellular Hsp72: the role of adrenal hormones
    • Fleshner M., Campisi J., Amiri L., and Diamone D.M. Cat exposure induces both intra- and extracellular Hsp72: the role of adrenal hormones. Psychoneuroendocrinology. 29 (2004) 1142-1152
    • (2004) Psychoneuroendocrinology. , vol.29 , pp. 1142-1152
    • Fleshner, M.1    Campisi, J.2    Amiri, L.3    Diamone, D.M.4
  • 16
    • 0031656163 scopus 로고    scopus 로고
    • Acute stressor exposure both suppresses acquired immunity and potentiate innate immunity
    • Fleshner M., Nguyen K.T., Cotter C.S., Watkins L.R., and Maier L.R. Acute stressor exposure both suppresses acquired immunity and potentiate innate immunity. Am. J. Physiol. 275 (1998) R870-R878
    • (1998) Am. J. Physiol. , vol.275
    • Fleshner, M.1    Nguyen, K.T.2    Cotter, C.S.3    Watkins, L.R.4    Maier, L.R.5
  • 17
    • 0035861792 scopus 로고    scopus 로고
    • The effects of Eleutherococcus senticosus and Pena ginseng on steroidal hormoneindices of stress and lymphocyte subset numbers in endurance athletes
    • Gaffney B.T., Hugel H.M., and Rich P.A. The effects of Eleutherococcus senticosus and Pena ginseng on steroidal hormoneindices of stress and lymphocyte subset numbers in endurance athletes. Life Sci. 70 (2001) 431-442
    • (2001) Life Sci. , vol.70 , pp. 431-442
    • Gaffney, B.T.1    Hugel, H.M.2    Rich, P.A.3
  • 18
    • 0012964229 scopus 로고    scopus 로고
    • Voluntary freewheel running selectively modulates catecholamine content in peripheral tissue and c-Fos expression in the central sympathetic circuit following exposure to uncontrollable stress in rats
    • Greenwood B.N., Kennedy S., Smith T.P., Campeau S., Day H.E., and Fleshner M. Voluntary freewheel running selectively modulates catecholamine content in peripheral tissue and c-Fos expression in the central sympathetic circuit following exposure to uncontrollable stress in rats. Neuroscience 120 (2003) 269-281
    • (2003) Neuroscience , vol.120 , pp. 269-281
    • Greenwood, B.N.1    Kennedy, S.2    Smith, T.P.3    Campeau, S.4    Day, H.E.5    Fleshner, M.6
  • 20
    • 0034485512 scopus 로고    scopus 로고
    • Critical roles of Toll-like receptors in host defence
    • Kaisho T., and Akira S. Critical roles of Toll-like receptors in host defence. Crit. Rev. Immunol. 20 (2000) 393-405
    • (2000) Crit. Rev. Immunol. , vol.20 , pp. 393-405
    • Kaisho, T.1    Akira, S.2
  • 21
    • 0345714711 scopus 로고    scopus 로고
    • The inhibitory effect of ginseng saponins on the stress-induced plasma interleukin-6 level in mice
    • Kim D.H., Moon Y.S., Lee T.H., Jung J.S., Suh H.W., and Song D.K. The inhibitory effect of ginseng saponins on the stress-induced plasma interleukin-6 level in mice. Neurosci. Lett. 1 (2003) 13-16
    • (2003) Neurosci. Lett. , vol.1 , pp. 13-16
    • Kim, D.H.1    Moon, Y.S.2    Lee, T.H.3    Jung, J.S.4    Suh, H.W.5    Song, D.K.6
  • 22
    • 0031966674 scopus 로고    scopus 로고
    • Acidic polysaccharide from Panax ginseng, ginsan, induces Th1 cell and macrophage cytokines and generates LAK cells in synergy with rIL-2
    • Kim K.H., Lee Y.S., Jung I.S., Park S.Y., Chung H.Y., Lee I.R., and Yun Y.S. Acidic polysaccharide from Panax ginseng, ginsan, induces Th1 cell and macrophage cytokines and generates LAK cells in synergy with rIL-2. Planta Med. 64 (1998) 110-115
    • (1998) Planta Med. , vol.64 , pp. 110-115
    • Kim, K.H.1    Lee, Y.S.2    Jung, I.S.3    Park, S.Y.4    Chung, H.Y.5    Lee, I.R.6    Yun, Y.S.7
  • 23
    • 4844220475 scopus 로고    scopus 로고
    • Ginseng modulates the immune response by induction of interleukin-12
    • Larsen M.W., Moser C., Hoiby N., Song Z., and Kharazmi A. Ginseng modulates the immune response by induction of interleukin-12. APMIS. 112 (2004) 369-373
    • (2004) APMIS. , vol.112 , pp. 369-373
    • Larsen, M.W.1    Moser, C.2    Hoiby, N.3    Song, Z.4    Kharazmi, A.5
  • 24
    • 0030838299 scopus 로고    scopus 로고
    • Ginsenoside-Rg1, one of the major active molecules from Panax ginseng, is a functional ligand of glucocorticoid receptor
    • Lee Y.J., Chung E., Lee K.Y., Lee Y.H., Huh B., and Lee S.K. Ginsenoside-Rg1, one of the major active molecules from Panax ginseng, is a functional ligand of glucocorticoid receptor. Mol. Cell. Endocrinol. 2 (1997) 135-140
    • (1997) Mol. Cell. Endocrinol. , vol.2 , pp. 135-140
    • Lee, Y.J.1    Chung, E.2    Lee, K.Y.3    Lee, Y.H.4    Huh, B.5    Lee, S.K.6
  • 25
    • 0025372712 scopus 로고
    • The effects of psychological stress on plasma interleukin-6 activity in rats
    • LeMay L.G., Vander A.J., and Kluger M.J. The effects of psychological stress on plasma interleukin-6 activity in rats. Physiol. Behav. 47 (1990) 957-961
    • (1990) Physiol. Behav. , vol.47 , pp. 957-961
    • LeMay, L.G.1    Vander, A.J.2    Kluger, M.J.3
  • 26
    • 0035219948 scopus 로고    scopus 로고
    • Changes in skeletal muscle heat shock proteins: pathological significance
    • Liu Y., and Steinacker J.M. Changes in skeletal muscle heat shock proteins: pathological significance. Front. Biosci. 6 (2001) D12-D25
    • (2001) Front. Biosci. , vol.6
    • Liu, Y.1    Steinacker, J.M.2
  • 27
    • 0002261456 scopus 로고    scopus 로고
    • Immunoglobulin, antibody, and exercise
    • Mackinnon L.T. Immunoglobulin, antibody, and exercise. Exerc. Immunol. Rev. 2 (1996) 1-35
    • (1996) Exerc. Immunol. Rev. , vol.2 , pp. 1-35
    • Mackinnon, L.T.1
  • 28
    • 0035985916 scopus 로고    scopus 로고
    • Beta-adrenergic signaling and thryoid hormones affect HSP72 expression during heat acclimation
    • Maloyan A., and Horowitz M. Beta-adrenergic signaling and thryoid hormones affect HSP72 expression during heat acclimation. J. Appl. Physiol. 93 (2002) 107-115
    • (2002) J. Appl. Physiol. , vol.93 , pp. 107-115
    • Maloyan, A.1    Horowitz, M.2
  • 29
    • 0030831210 scopus 로고    scopus 로고
    • A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
    • Medzhitov R., Preston-Hurlburt P., and Janeway Jr. C.A. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 388 (1997) 394-397
    • (1997) Nature , vol.388 , pp. 394-397
    • Medzhitov, R.1    Preston-Hurlburt, P.2    Janeway Jr., C.A.3
  • 30
    • 0034035486 scopus 로고    scopus 로고
    • Exercise immunology: future directions for research related to athletes, nutrition and the elderly
    • Nieman D.C. Exercise immunology: future directions for research related to athletes, nutrition and the elderly. Int. J. Sports Med. 21 Suppl 1 (2000) S61-S68
    • (2000) Int. J. Sports Med. , vol.21 , Issue.SUPPL. 1
    • Nieman, D.C.1
  • 31
    • 0041765653 scopus 로고    scopus 로고
    • How stress influences the immune response
    • Padgett D.A., and Glaser R. How stress influences the immune response. Trends Immunol. 24 (2003) 444-448
    • (2003) Trends Immunol. , vol.24 , pp. 444-448
    • Padgett, D.A.1    Glaser, R.2
  • 32
    • 0034293075 scopus 로고    scopus 로고
    • Special feature for the Olympics: effects of exercise on the immune system: exercise and cytokines
    • Pedersen B.K. Special feature for the Olympics: effects of exercise on the immune system: exercise and cytokines. Immunol. Cell Biol. 78 (2000) 532-535
    • (2000) Immunol. Cell Biol. , vol.78 , pp. 532-535
    • Pedersen, B.K.1
  • 33
    • 0033922490 scopus 로고    scopus 로고
    • Exercise and the immune system: regulation, integration, and adaptation
    • Pedersen B.K., and Hoffman-Goetz L. Exercise and the immune system: regulation, integration, and adaptation. Physiol. Rev. 80 (2000) 1055-1081
    • (2000) Physiol. Rev. , vol.80 , pp. 1055-1081
    • Pedersen, B.K.1    Hoffman-Goetz, L.2
  • 34
    • 1042304299 scopus 로고    scopus 로고
    • Anti-stress effects of Ginkgo biloba and Panax ginseng: a comparative study
    • Rai D., Bhatia G., Sen T., and Palit G. Anti-stress effects of Ginkgo biloba and Panax ginseng: a comparative study. J. Pharmacol. Sci. 4 (2003) 458-464
    • (2003) J. Pharmacol. Sci. , vol.4 , pp. 458-464
    • Rai, D.1    Bhatia, G.2    Sen, T.3    Palit, G.4
  • 35
    • 0030945995 scopus 로고    scopus 로고
    • Characterization of early cytokine responses and an interleukin (IL)-6-dependent pathway of endogenous glucocorticoid induction during murine cytomegalovirus infection
    • Ruzek M.C., Miller A.H., Opal S.M., Pearce B.D., and Biron C.A. Characterization of early cytokine responses and an interleukin (IL)-6-dependent pathway of endogenous glucocorticoid induction during murine cytomegalovirus infection. J. Exp. Med. 185 (1997) 1185-1192
    • (1997) J. Exp. Med. , vol.185 , pp. 1185-1192
    • Ruzek, M.C.1    Miller, A.H.2    Opal, S.M.3    Pearce, B.D.4    Biron, C.A.5
  • 37
    • 0030330575 scopus 로고    scopus 로고
    • Efficacy and safety of the standardized ginseng extract G115 for potentiating vaccination against common cold and/or influenza syndrome
    • Scaglione F., Cattaneo G., Alessandria M., and Cogo R. Efficacy and safety of the standardized ginseng extract G115 for potentiating vaccination against common cold and/or influenza syndrome. Drugs Exp. Clin. Res. 22 (1996) 65-72
    • (1996) Drugs Exp. Clin. Res. , vol.22 , pp. 65-72
    • Scaglione, F.1    Cattaneo, G.2    Alessandria, M.3    Cogo, R.4
  • 38
    • 0036385569 scopus 로고    scopus 로고
    • Immunostimulating effects of acid polysaccharides extract of Panax ginseng on macrophages function
    • Shin J.Y., Song Z.J., Yun Y.S., Yang H.O., Rhee D.K., and Pio S. Immunostimulating effects of acid polysaccharides extract of Panax ginseng on macrophages function. Immunopharmacol. Immunotoxicol. 24 (2002) 469-482
    • (2002) Immunopharmacol. Immunotoxicol. , vol.24 , pp. 469-482
    • Shin, J.Y.1    Song, Z.J.2    Yun, Y.S.3    Yang, H.O.4    Rhee, D.K.5    Pio, S.6
  • 39
    • 0019048612 scopus 로고
    • HPLC separation and quantitative determination of ginsenosides from Panax ginseng, Panax quinquefolium and from ginseng drug preparations
    • Soldati F., and Sticher O. HPLC separation and quantitative determination of ginsenosides from Panax ginseng, Panax quinquefolium and from ginseng drug preparations. Planta Med. 4 (1980) 348-357
    • (1980) Planta Med. , vol.4 , pp. 348-357
    • Soldati, F.1    Sticher, O.2
  • 40
    • 0030740081 scopus 로고    scopus 로고
    • Ginseng treatment enhances bacterial clearance and decreases lung pathology in athymic rats with chronic P. aeruginosa pneumonia
    • Song Z.J., Johansen H.K., Faber V., and Hoiby N. Ginseng treatment enhances bacterial clearance and decreases lung pathology in athymic rats with chronic P. aeruginosa pneumonia. APMIS 105 (1997) 438-444
    • (1997) APMIS , vol.105 , pp. 438-444
    • Song, Z.J.1    Johansen, H.K.2    Faber, V.3    Hoiby, N.4
  • 41
    • 0034052503 scopus 로고    scopus 로고
    • Activation of HSF and selective increase in heat-shock proteins by acute dexamethasone treatment
    • Sun L., Chang J., et al. Activation of HSF and selective increase in heat-shock proteins by acute dexamethasone treatment. Am. J. Physiol. Heart Circ. Physiol. 4 (2000) H1091-H1097
    • (2000) Am. J. Physiol. Heart Circ. Physiol. , vol.4
    • Sun, L.1    Chang, J.2
  • 42
    • 0028294459 scopus 로고
    • Endocrine control of stress-induced heat shock protein 70 expression in vivo
    • Udelsman R., Blake M.J., et al. Endocrine control of stress-induced heat shock protein 70 expression in vivo. Surgery 5 (1994) 611-616
    • (1994) Surgery , vol.5 , pp. 611-616
    • Udelsman, R.1    Blake, M.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.