Lymphatic mapping and sentinel node analysis: Current concepts and applications

Ca-A Cancer Journal for Clinicians

Volumn 56, Issue 5, 2006, Pages 292-309

  Chen, Steven L ^a   Iddings, Douglas M ^a   Scheri, Randall P ^a   Bilchik, Anton J ^a,b  

^a JOHN WAYNE CANCER INSTITUTE   (United States)

^b Gastrointestinal Program   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKERATIN;

BREAST CANCER; CLINICAL TRIAL; COLON CANCER; COLORECTAL CANCER; ESOPHAGUS CANCER; HEAD AND NECK CANCER; HUMAN; IMMUNOHISTOCHEMISTRY; LUNG CANCER; LYMPHOSCINTIGRAPHY; MELANOMA; PRIORITY JOURNAL; REVIEW; SENTINEL LYMPH NODE BIOPSY; SKIN CANCER; STOMACH CANCER; THYROID CANCER; THYROID CARCINOMA;

BREAST NEOPLASMS; FEMALE; GASTROINTESTINAL NEOPLASMS; HEAD AND NECK NEOPLASMS; HUMANS; LUNG NEOPLASMS; LYMPHATIC METASTASIS; MALE; NEOPLASMS; SENTINEL LYMPH NODE BIOPSY; SKIN NEOPLASMS; THYROID NEOPLASMS;

EID: 33749520824     PISSN: 00079235     EISSN: 15424863     Source Type: Journal    
DOI: 10.3322/canjclin.56.5.292     Document Type: Review

References (160)

1. Morton D, Cagle L, Wong J, et al. Intraoperative lymphatic mapping and selective lymphadenectomy: technical details of a new procedure for clinical stage I melanoma. Presented at: Annual Meeting of the Society Surgical Oncology; May 1990, Washington, DC.
2. Morton DL, Wen DR, Wong JH, et al. Technical details of intraoperative lymphatic mapping for early stage melanoma. Arch Surg 1992;127:392-399.
3. Giuliano AE, Kirgan DM, Guenther JM, Morton DL. Lymphatic mapping and sentinel lymphadenectomy for breast cancer. Ann Surg 1994;220:391-398.
4. Wilke LG, McCall LM, Posther KE, et al. Surgical complications associated with sentinel lymph node biopsy: results from a prospective international cooperative trial. Ann Surg Oncol 2006;13:491-500.
5. Schrenk P, Rieger R, Shamiyeh A, Wayand W. Morbidity following sentinel lymph node biopsy versus axillary lymph node dissection for patients with breast carcinoma. Cancer 2000;88:608-614.
6. Purushotham AD, Upponi S, Klevesath MB, et al. Morbidity after sentinel lymph node biopsy in primary breast cancer: results from a randomized controlled trial. J Clin Oncol 2005;23:4312-4321.
7. Greene FL, Page DL, Fleming ID, et al. AJCC Cancer Staging Manual. 6th ed. New York: Springer-Verlag; 2002.
8. Essner R, Cochran AJ. Sentinel node biopsy: not only a staging tool? Recent Results Cancer Res 2002;160:133-148.
9. Xu X, Roberts SA, Pasha TL, et al. Undesirable cytokeratin immunoreactivity of native nonepithelial cells in sentinel lymph nodes from patients with breast carcinoma. Arch Pathol Lab Med 2000;124:1310-1313.
10. Bostick PJ, Morton DL, Turner RR, et al. Prognostic significance of occult metastases detected by sentinel lymphadenectomy and reverse transcriptase-polymerase chain reaction in early-stage melanoma patients. J Clin Oncol 1999;17:3238-3244.
11. Morton DL, Hoon DS, Cochran AJ, et al. Lymphatic mapping and sentinel lymphadenectomy for early-stage melanoma: therapeutic utility and implications of nodal microanatomy and molecular staging for improving the accuracy of detection of nodal micrometastases. Ann Surg 2003;238:538-549.
12. Lockett MA, Baron PL, O'Brien PH, et al. Detection of occult breast cancer micrometastases in axillary lymph nodes using a multimarker reverse transcriptase-polymerase chain reaction panel. J Am Coll Surg 1998;187:9-16.
13. Noguchi S, Aihara T, Nakamori S, et al. The detection of breast carcinoma micrometastases in axillary lymph nodes by means of reverse transcriptase-polymerase chain reaction. Cancer 1994;74:1595-1600.
14. Aihara T, Fujiwara Y, Ooka M, et al. Mammaglobin B as a novel marker for detection of breast cancer micrometastases in axillary lymph nodes by reverse transcription-polymerase chain reaction. Breast Cancer Res Treat 1999;58:137-140.
15. Wascher RA, Bostick PJ, Huynh KT, et al. Detection of the MAGE-A3 in breast cancer patients' sentinel nodes. Br J Cancer 2001;85:1340-1346.
16. Bilchik AJ, Saha S, Wiese D, et al. Molecular staging of early colon cancer and its impact on staging. Ann Surg Oncol 2000;7:120-124.
17. Kammula US, Ghossein R, Bhattacharya S, Coit DG. Serial follow-up and the prognostic significance of reverse transcriptase-polymerase chain reaction-staged sentinel lymph nodes from melanoma patients. J Clin Oncol 2004;22:3989-3996.
18. Leong SP, Donegan E, Heffernon W, et al. Adverse reactions to isosulfan blue during selective sentinel lymph node dissection in melanoma. Ann Surg Oncol 2000;7:361-366.
19. Blessing WD, Stolier AJ, Teng SC, et al. A comparison of methylene blue and lymphazurin in breast cancer sentinel node mapping. Am J Surg 2002;184:341-345.
20. Simmons R, Thevarajah S, Brennan MB, et al. Methylene blue dye as an alternative to isosulfan blue dye for sentinel lymph node localization. Ann Surg Oncol 2003;10:242-247.
21. Gershenwald JE, Tseng CH, Thompson W, et al. Improved sentinel lymph node localization in patients with primary melanoma with the use of radiolabelled colloid. Surgery 1998;24:203-210.
22. Krag DN, Meijer SJ, Weaver DL, et al. Minimal access surgery for staging of malignant melanoma. Arch Surg 1994;130:654-658.
23. Essner R. The role of lymphoscintigraphy and sentinel node mapping in assessing patient risk in melanoma. Semin Oncol 1997;24:S8-S10.
24. McMasters KM, Reintgen DS, Ross MI, et al. Sentinel lymph node biopsy for melanoma: how many radioactive nodes should be removed? Ann Surg Oncol 2001;8:192-197.
25. Stratmann SL, McCarty TM, Kuhn JA. Radiation safety with breast sentinel node biopsy. Am J Surg 1999;178:454-457.
26. Balch CM, Soong SJ, Murad TM, et al. A multifactorial analysis of melanoma. II. Prognostic factors in patients with stage I (localized) melanoma. Surgery 1979;86:343-351.
27. Milton GW, Shaw HM, McCarthy WH, et al. Prophylactic lymph node dissection in clinical stage I cutaneous malignant melanoma: results of surgical treatment in 1319 patients. Br J Surg 1982;69:108-111.
28. Sim FH, Taylor WF, Ivins JC, et al. A prospective randomized study of the efficacy of routine elective lymphadenectomy in management of malignant melanoma. Preliminary results. Cancer 1978;41:948-956.
29. Veronesi U, Adamus J, Bandiera DC, et al. Inefficacy of immediate node dissection in stage 1 melanoma of the limbs. N Engl J Med 1977;297:627-630.
30. Veronesi U, Adamus J, Bandiera DC, et al. Delayed regional lymph node dissection in stage I melanoma of the skin of the lower extremities. Cancer 1982;49:2420-2430.
31. Balch CM, Soong SJ, Bartolucci AA, et al. Efficacy of an elective regional lymph node dissection of 1 to 4 mm thick melanomas for patients 60 years of age and younger. Ann Surg 1996;224:255-266.
32. Balch CM, Soong SJ, Milton GW, et al. A comparison of prognostic factors and surgical results in 1,786 patients with localized (stage I) melanoma treated in Alabama, USA, and New South Wales, Australia. Ann Surg 1982;196:677-684.
33. Kelley MC, Ollila DW, Morton DL. Lymphatic mapping and sentinel lymphadenectomy for melanoma. Semin Surg Oncol 1998;14:283-290.
34. Glass EC, Essner R, Morton DL. Kinetics of three lymphoscintigraphic agents in patients with cutaneous melanoma. J Nucl Med 1998;39:1185-1190.
35. Haigh PI, Lucci A, Turner RR, et al. Carbon dye histologically confirms the identity of sentinel nodes in cutaneous melanoma. Cancer 2001;92:535-541.
36. Cochran AJ, Wen DR, Morton DL. Management of the regional lymph nodes in patients with cutaneous malignant melanoma. World J Surg 1992;16:214-221.
37. Leong SP, Steinmetz I, Habib FA, et al. Optimal selective sentinel lymph node dissection in primary malignant melanoma. Arch Surg 1997;132:666-673.
38. Morton DL, Thompson JF, Essner R, et al. Validation of the accuracy of intraoperative lymphatic mapping and sentinel lymphadenectomy for earlystage melanoma: a multicenter trial. Multicenter Selective Lymphadenectomy Trial Group. Ann Surg 1999;230:453-465.
39. Morton DL, Cochran AJ, Thompson JF, et al. Sentinel node biopsy for early-stage melanoma accuracy and morbidity in MSLT-1, an international multicenter trial. Ann Surg 2005;242:302-313.
40. Morton DL, Thompson JF, Cochran AJ, et al. 2005 ASCO Annual Meeting Proceedings. J Clin Oncol 2005;23:7500.
41. de Hullu JA, Hollema H, Piers DA, et al. Sentinel lymph node dissection is highly accurate in squamous cell carcinoma of the vulva. J Clin Oncol 2000;18:2811-2816.
42. Bilchik AJ, Giuliano A, Essner R, et al. Universal application of intraoperative lymphatic mapping and sentinel lymphadenectomy in solid neoplasms. Cancer J Sci Am 1998;4:351-358.
43. Hill AD, Brady MS, Coit DG. Intraoperative mapping and sentinel lymph node biopsy for Merkel cell carcinoma. Br J Surg 1999;86:518-521.
44. Wagner JD, Evdokimov DZ, Weisberger E, et al. Sentinel lymph biopsy for high risk nonmelanoma cutaneous malignancy. Arch Dermatol 2004;140:75-79.
45. Carter CL, Allen C, Henson DE. Relation of tumor size, lymph node status, and survival in 24,740 breast cancer cases. Cancer 1989;63:181-187.
46. Fisher ER, Anderson S, Redmond C, et al. Pathologic findings from the National Surgical Adjuvant Breast Project Protocol B-06. 10-year pathologic and clinical prognostic discriminants. Cancer 1993;71:2507-2514.
47. Halsted W. The results of operations for the cure of cancer of the breast performed at the Johns Hopkins Hospital from June, 1889, to January, 1894. Johns Hopkins Hosp Bull 1894;4:297-323.
48. Giuliano AE, Kirgan DM, Guenther JM, Morton DL. Lymphatic mapping and sentinel lymphadenectomy for breast cancer. Ann Surg 1994;220:391-398.
49. Krag DN, Weaver DL, Alex JC, Fairbank JT. Surgical resection and radiolocalization of the sentinel lymph node in breast cancer using a gamma probe. Surg Oncol 1993;2:335-339.
50. Albertini JJ, Lyman GH, Cox C, et al. Lymphatic mapping and sentinel node biopsy in the patient with breast cancer. JAMA 1996;276:1818-1822.
51. Giuliano AE, Jones RC, Brennan M, et al. Sentinel lymphadenectomy in breast cancer. J Clin Oncol 1997;15:2345-2350.
52. Krag D, Weaver D, Ashikaga T, et al. The sentinel node in breast cancer - a multicenter validation study. N Engl J Med 1998;339:941-946.
53. McMasters KM, Tuttle TM, Carlson DJ, et al. Sentinel lymph node biopsy for breast cancer: a suitable alternative to routine axillary dissection in multi-institutional practice when optimal technique is used. J Clin Oncol 2000;18:2560-2566.
54. Hsueh EC, Hansen N, Giuliano AE. Intraoperative lymphatic mapping and sentinel lymph node dissection in breast cancer. CA Cancer J Clin 2000;50:279-291.
55. Povoski SP, Olsen JO, Young DC, et al. Prospective randomized trial comparing intrdermal, intraparenchymal, and subareolar injection routes for sentinel lymph node mapping and biopsy in breast cancer. Ann Surg Oncol 2006;13:S10-S11.
56. Wong SL, Chao C, Edwards MJ, et al. Accuracy of sentinel lymph node biopsy for patients with T2 and T3 breast cancers. Am Surg 2001;67:522-526.
57. Bedrosian I, Reynolds C, Mick R, et al. Accuracy of sentinel lymph node biopsy in patients with large primary breast tumors. Cancer 2000;88:2540-2545.
58. Chung MH, Ye W, Giuliano AE. Role for sentinel lymph node dissection in the management of large (≥5 cm) invasive breast cancer. Ann Surg Oncol 2001;8:688-692.
59. Pendas S, Dauway E, Giuliano R, et al. Sentinel node biopsy in ductal carcinoma in situ patients. Ann Surg Oncol 2000;7:15-20.
60. Reitsamer R, Peintinger F, Rettenbacher L, et al. Sentinel lymph node biopsy in breast cancer patients after neoadjuvant chemotherapy. J Surg Oncol 2003;84:63-67.
61. Mamounas EP, Brown A, Anderson S, et al. Sentinel node biopsy after neoadjuvant chemotherapy in breast cancer: results from National Surgical Adjuvant Breast and Bowel Project Protocol B-27. J Clin Oncol 2005;23:2694-2702.
62. Lyman GH, Giuliano AE, Somerfield MR, et al. American Society of Clinical Oncology. American Society of Clinical Oncology guideline recommendations for sentinel lymph node biopsy in early-stage breast cancer. J Clin Oncol 2005;23:7703-7720.
63. Sabel MS, Schott AF, Kleer CG, et al. Sentinel node biopsy prior to neoadjuvant chemotherapy. Am J Surg 2003;186:102-105.
64. Singletary SE, Connolly JL. Breast cancer staging: working with the sixth edition of the AJCC cancer staging manual. CA Cancer J Clin 2006;56:37-47.
65. National Cancer Institute. Phase III randomized study of surgical resection with or without axillary lymph node dissection in women with clinically node-negative breast cancer with sentinel node micrometastases. Available at: http://www.cancer.gov/clinicaltrials/IBCSG-23-01. Accessed on April 17, 2006.
66. American College of Surgeons Oncology Group. A prognostic study of sentinel node and bone marrow micrometastases in women with clinical T1 or T2 N0 M0 breast cancer. Available at: https://www.acosog.org/studies/synopses/ Z0010_Synopsis.pdf. Accessed April 17, 2006.
67. Brogi E, Torres-Matundan E, Tan LK, Cody HS III. The results of frozen section, touch preparation, and cytological smear are comparable for introperative examination of sentinel lymph nodes: a study of 133 breast cancer patients. Ann Surg Oncol 2005;12:173-180.
68. Cox CE, Furman B, Dupont EL, et al. Novel techniques in sentinel lymph node mapping and localization of nonpalpable breast lesions: the Moffitt experience. Ann Surg Oncol 2004;11:222S-2226S.
69. Cox CE, Salud CJ, Cantor A, et al. Learning curves for breast cancer sentinel lymph node mapping based on surgical volume analysis. J Am Coll Surg 2001;193:593-600.
70. Tafra L, Lannin DR, Swanson MS, et al. Multicenter trial of sentinel node biopsy for breast cancer using both technetium sulfur colloid and isosulfan blue dye. Ann Surg 2001;233:51-59.
71. Veronesi U, Paganelli G, Viale G, et al. A randomized comparison of sentinel-node biopsy with routine axillary dissection in breast cancer. N Eng J Med 2003;349:546-553.
72. Swanson RS, Compton CC, Stewart AK, Bland KI. The prognosis of T3N0 colon cancer is dependent on the number of lymph nodes examined. Ann Surg Oncol 2003;10:65-71.
73. Le Voyer TE, Sigurdson ER, Hanlon AL, et al. Colon cancer survival in associated with increasing number of lymph nodes analyzed: a secondary survey of Intergroup trial INT-0089. J Clin Oncol 2003;21:2912-2919.
74. André T, Boni C, Mounedji-Boudiaf L, et al. Oxaliplatin, fluorouracil, and leucovorin as adjuvant treatment for colon cancer. N Eng J Med 2004;350:2343-2351.
75. Benson AB, Schrag D, Somerfield MR, et al. American Society of Clinical Oncology recommendations on adjuvant chemotherapy for stage II colon cancer. J Clin Oncol 2004;22:3408-3419.
76. Grothey A, Sargent DJ. FOLFOX for Stage II Colon Cancer? A commentary on the recent FDA approval of oxaliplatin for adjuvant therapy of stage III colon cancer. J Clin Oncol 2005;23:3311-3313.
77. Wong JH, Steineman S, Calderia C, et al. Ex vivo sentinel node mapping in carcinoma of the colon and rectum. Ann Surg 2001;233:515-521.
78. Wong JH, Johnson DS, Namiki T, et al. Validation of ex vivo lymphatic mapping in hematoxylin-eosin node-negative carcinoma of the colon and rectum. Ann Surg Oncol 2004;11:772-777.
79. Tuech JJ, Pessaux P, Di Fiore F, et al. Sentinel node mapping in colon carcinoma: in-vivo versus ex-vivo approach. Eur J Surg Oncol 2006;32:158-161.
80. Joosten JJ, Strobbe LJ, Wauters CA, et al. Intraoperative lymphatic mapping and the sentinel node concept in colorectal carcinoma. Br J Surg 1999;86:482-486.
81. Bilchik AJ, Saha S, Wiese D, et al. Molecular staging of early colon cancer on the basis of sentinel node analysis: a multicenter phase II trial. J Clin Oncol 2001;19:1128-1136.
82. Stojadinovic A, Allen PJ, Protic M, et al. Colon sentinel lymph node mapping: practical surgical applications. J Am Coll Surg, 2005;297-313.
83. Bertagnolli M, Miedema B, Redston M, et al. Sentinel node staging of resectable colon cancer: results of a multicenter study. Ann Surg 2004;240:624-630.
84. Redston M, Compton CC, Miedema BW, et al. Analysis of micrometastatic disease in sentinel lymph nodes from resectable colon cancer: results of cancer and leukemia group B trial 80001. J Clin Oncol 2006;24:878-883.
85. Saha S, Seghal R, Patel M, et al. A multicenter trial of sentinel lymph node mapping in colorectal cancer: prognostic implications for nodal staging and recurrence. Am J Surg 2006;191:305-310.
86. Bilchik AJ, DiNome M, Saha S, et al. Prospective multi-center trial of staging adequacy in colon cancer: preliminary results. Arch Surg 2006;141:527-534.
87. Braat AE, Oosterhuis JW, Moll FC, et al. Sentinel node detection after preoperative short-course radiotherapy in rectal carcinoma is not reliable. Br J Surg 2005;92:1533-1538.
88. Roukos DH. Current status and future perspectives in gastric cancer management. Cancer Treat Rev 2000;26:243-245.
89. Tsioulias GJ, Wood TF, Morton DL, Bilchik AJ. Lymphatic mapping and focused analysis of sentinel lymph nodes upstage gastrointestinal neoplasms. Arch Surg 2000;135:926-932.
90. Sano T, Katai H, Sasko M, et al. Gastric lymphadenectomy and detection of sentinel nodes. Recent Results Cancer Res 2000;157:253-258.
91. De Manzoni G, Verlato G, Guglielmi A, et al. Prognostic significance of lymph node dissection in gastric cancer. Br J Surg 1996;83:1604-1607.
92. Siewert JR, Bottcher K, Stein HJ, et al. Relevant prognostic factors in gastric cancer: ten-year results of the German gastric cancer study. Ann Surg 1998;228:449-461.
93. Ichikura T, Chochi K, Sugasawa H, et al. Individualized surgery for early gastric cancer guided by sentinel node biopsy. Surgery 2006;139:501-507.
94. Macdonald JS, Smalley SR, Benedetti J, et al. Chemoradiotherapy after surgery compared with surgery alone for adenocarcinoma of the stomach or gastroesophageal junction. N Engl J Med 2001;345:725-730.
95. Kitagawa Y, Fujii H, Kumai K, et al. Recent advances in sentinel node navigation for gastric cancer: a paradigm shift of surgical management. J Surg Oncol 2005;90:147-152.
96. Zulfikaroglu B, Koc M, Ozmen MM, et al. Intraoperative lymphatic mapping and sentinel lymph node biopsy using radioactive tracer in gastric cancer. Surgery 2005;138:899-904.
97. Kitagawa Y, Fujii H, Mukai M, et al. Sentinel lymph node mapping in esophageal and gastric cancer. Cancer Treat Res 2005;127:123-139.
98. Park DJ, Lee HJ, Lee HS, et al. Sentinel node biopsy for cT1 and cT2a gastric cancer. Eur J Surg Oncol 2006;32:48-54.
99. Kitagawa Y, Fujii H, Mukai M, et al. The role of the sentinel lymph node in gastrointestinal cancer. Surg Clin North Am 2000;80:799-809.
100. Yasuda S, Shimada H, Chino O, et al. Sentinel lymph node detection with Tc-99m tin colloids in patients with esophagogastric cancer. Jpn J Clin Oncol 2003;33:68-72.
101. Udagawa H, Akiyama H. Surgical treatment of esophageal cancer: Tokyo experience of the three-field technique. Dis Esophagus 2001;14:110-114.
102. Kitagawa Y, Fujii H, Mukai M, et al. Current status and future prospects of sentinel node navigational surgery for gastrointestinal cancers. Ann Surg Oncol 2004;11:242S-244S.
103. Udagawa H. Sentinel node concept in esophageal surgery: an elegant strategy. Ann Thorac Cardiovasc Surg 2005;11:1-3.
104. Lamb PJ, Griffen SM, Burt AD, et al. Sentinel node biopsy to evaluate the metastatic dissemination of oesophageal adenocarcinoma. Br J Surg 2005;92:60-67.
105. Alex JC, Sasaki CT, Krag DN, et al. Sentinel lymph node radiolocalization in head and neck squamous cell carcinoma. Laryngoscope 2000;110:198-203.
106. Shoaib T, Soutar DS, Prosser JE, et al. A suggested method for sentinel lymph node biopsy in squamous cell carcinoma of the head and neck. Head Neck 1999;21:728-733.
107. Stoeckli SJ, Steinert H, Pfaltz M, Schmid S. Sentinel lymph node evaluation in squamous cell carcinoma of the head and neck. Otolaryngol Head Neck Surg 2001:125;221-226.
108. Civanto FJ, Gomez C, Duque C, et al. Sentinel node biopsy in oral cavity cancer: correlation with PET scan and immunohistochemistry. Head Neck 2003;25:1-9.
109. Barzan L, Sulfaro S, Alberti F, et al. Gamma probe accuracy in detecting the sentinel node in clinically N0 squamous cell carcinoma of the head and neck. Ann Otol Rhinol Laryngol 2002;111:794-798.
110. Mozzillo N, Chiesa F, Botti G, et al. Sentinel node biopsy in head and neck cancer. Ann Surg Oncol 2001;8:1035-1055.
111. Stoeckli SJ, Pfaltz M, Ross GL, et al. The second international conference on sentinel node biopsy in mucosal head and neck cancer. Ann Surg Oncol 2005;12:919-924.
112. Paleri V, Rees G, Arullendran P, et al. Sentinel node biopsy in squamous cell cancer of the oral cavity and oral pharynx: a diagnostic meta-analysis. Head Neck 2005;27:739-747.
113. Ross GL, Soutar DS, Gordon MacDonald D, et al. Sentinel node biopsy in head and neck cancer: preliminary results of a multicenter trial. Ann Surg Oncol 2004;11:690-696.
114. Ross G, Shoaib T, Soutar D, et al. The use of sentinel node biopsy to upstage the clinically N0 neck in head and neck cancer. Arch Otolaryngol Head Neck Surg 2002;128:1287-1291.
115. Ross GL, Soutar D, MacDonald DG, et al. Improved staging of cervical metastasis in clinically negative patients with head and neck squamous cell carcinoma. Ann Surg Oncol 2004;11:213-218.
116. Werner JA, Dunne AA, Ramaswamy A, et al. The sentinel node concept in head and neck cancer: solution for the controversies in the N0 neck? Head Neck 2004;26:603-611.
117. Kovacs AF, Acker P, Berner U, et al. Sentinel lymph node excision. Treatment method of the N0 neck in patients with oral and oropharyngeal carcinoma. HNO 2001;49:646-653.
118. Pitman KT, Johnson JT, Brown ML, Myers EN. Sentinel lymph node biopsy in head and neck carcinoma. Laryngoscope 2002;112:2101-2113.
119. Shoaib T, Soutar DS, MacDonald DG, et al. The accuracy of head and neck carcinoma sentinel lymph node biopsy in the clinically N0 neck. Cancer 2001;91:2077-2083.
120. Pastore A, Turetta GD, Tarabini A, et al. Sentinel lymph node analysis in squamous cell carcinoma of the oral cavity and oralpharynx. Tumori 2002;88:S58-S60.
121. Hay ID, Bergstralh EJ, Goellner JR, et al. Predicting outcome in papillary thyroid carcinoma: development of a reliable prognostic scoring system in a cohort of 1779 patients surgically treated at one institution during 1940 through 1989. Surgery 1993;114:1050-1058.
122. Shaha AR, Shah JP, Loree TR. Risk group stratification and prognostic factors in papillary carcinoma of thyroid. Ann Surg Oncol 1996;3:534-538.
123. Hughes CJ, Shaha AR, Shah JP, Loree TR. Impact of lymph node metastasis in differentiated carcinoma of the thyroid: a matched-pair analysis. Head Neck 1996;18:127-132.
124. Scheumann GF, Gimm O, Wegener G, et al. Prognostic significance and surgical management of locoregional lymph node metastases in papillary thyroid cancer. World J Surg 1994;18:559-568.
125. Keleman PR, Van Herle AJ, Giuliano AE. Sentinel lymphadenectomy in thyroid malignant neoplasms. Arch Surg 1998;133:288-292.
126. Pelizzo MR, Boschin IM, Toniato A, et al. Sentinel node procedure with Patent Blue V dye in surgical treatment of papillary thyroid carcinoma. Acta Otolaryngol 2001;121:421-424.
127. McHenry CR, Rosen IB, Walfish PG. Prospective management of nodal metastases in differentiated thyroid cancer. Am J Surg 1991;162:353-356.
128. Henry JF, Gramatica L, Denizot A, et al. Morbidity of prophylactic lymph node dissection in the central neck area in patients with thyroid carcinoma. Langenbecks Arch Surg 1998;383:167-169.
129. Johnson PR, Sehon J, Li BD. Potential utility of sentinel node biopsy in the original surgical assessment of Hurlthle cell tumors of the thyroid: 23-year institutional review of Hurthle cell neoplasms. J Surg Oncol 1999;70:100-102.
130. Dixon E, McKinnon JG, Pasieka JL. Feasibility of sentinel node biopsy and lymphatic mapping in nodular thyroid neoplasms. World J Surg 2000;24:1396-1401.
131. Haigh PI, Giuliano AE. Sentinel lymph node dissection for thyroid malignancy. Recent Results Cancer Res 2000;157:201-205.
132. Arch-Ferrer J, Velazquez D, Fajardo R, et al. Accuracy of sentinel node in papillary thyroid carcinoma. Surgery 2001;130:907-913.
133. Fukui Y, Yamakawa T, Taniki T, et al. Sentinel lymph node biopsy in patients with papillary thyroid carcinoma. Cancer 2001;92:2868-2874.
134. Gallowitsch HJ, Mikosch P, Kresnik E, et al. Lymphoscintigrapy and gamma probe-guided surgery in papillary thyroid carcinoma: the sentinel lymph node concept in thyroid carcinoma. Clin Nucl Med 1999;24:744-746.
135. Rettenbacher L, Sungler P, Gmeiner D, et al. Detecting the sentinel lymph node in patients with differentiated thyroid carcinoma. Eur J Nucl Med 2000;27:1399-1401.
136. Catarci M, Zaraca F, Angeloni R, et al. Preoperative lymphoscintigraphy and sentinel lymph node biopsy in papillary thyroid cancer. A pilot study. J Surg Oncol 2001;77:21-25.
137. Keller SM, Adak S, Wagner H, Johnson DH. Mediastinal lymph node dissection improves survival in patients with stages II and IIIa non-small cell lung cancer. Eastern Cooperative Oncology Group. Ann Thorac Surg 2000;70:358-365.
138. Graham AN, Chan KJ, Pastorino U, et al. Systemic nodal dissection in the intrathoracic staging of patients with non-small cell lung cancer. J Thorac Cardiovasc Surg 1999;117:246-251.
139. Izbicki JR, Passlick B, Pantel K, et al. Effectiveness of radical systematic mediastinal lymphadenectomy in patients with resectable nonsmall cell lung cancer: results of a prospective randomized trial. Ann Surg 1998;227:138-144.
140. Wu Y, Huang ZF, Wang SY, et al. A randomized trial of systematic nodal dissection in resectable non-small cell lung cancer. Lung Cancer 2002;36:1-6.
141. Kubuschok B, Passlick B, Izbicki JR, et al. Disseminated tumor cells in lymph nodes as a determinate for survival in surgically resected non-small cell lung cancer. J Clin Oncol 1999;17:19-24.
142. Osaki T, Oyama T, Gu CD, et al. Prognostic impact of micrometastatic tumor cells in the lymph nodes and bone marrow of patients with completely resectable stage I non-small cell lung cancer. J Clin Oncol 2002;20:2930-2936.
143. Little AG, DeHoyos A, Kirgan DM, et al. Intraoperative lymphtic mapping for non-small cell lung cancer: the sentinel node technique. J Thorac Cardiovasc Surg 1999;117:220-224.
144. Lardinois D, Brack T, Gaspert A, et al. Bronchoscopic radioisotope injection for sentinel lymph-node mapping in potentially resectable non small-cell lung cancer. Eur J Cardiothorac Surg 2003;23:824-827.
145. Liptay MJ, Masters GA, Winchenchester DJ, et al. Intraoperative radioisotope sentinel lymph node mapping in non-small cell lung cancer. Ann Thorac Surg 2000;70:384-389.
146. Melfi FM, Chella A, Menconi GF, et al. Intraoperative radioguided sentinel lymph node biopsy in non-small cell lung cancer. Eur J Cardiothorac Surg 2003;23:214-220.
147. Faries MB, Bleicher RJ, Ye X, et al. Lymphatic mapping and sentinel lymphadenectomy for primary and metastatic pulmonary malignant neoplasms. Arch Surg 2004;139:870-877.
148. Nakagawa T, Minamiya Y, Katayose Y, et al. A novel method for sentinel node mapping using magnetite in patients with non-small cell lung cancer. J Thorac Cardiovasc Surg 2003;126:563-567.
149. Nomori H, Horio H, Naruke T, et al. Use of technetium-99m tin colloid for sentinel lymph node identification in non-small cell lung cancer. J Thorac Cardiovasc Surg 2002;124;486-492.
150. Nomori H, Watanabe K, Ohtsuka T, et al. In vivo identification of sentinel lymph nodes for clinically stage I non-small cell lung cancer for abbreviation of mediastinal lymph node dissection. Lung Cancer 2004;46:49-55.
151. Pulte D, Li E, Crawford BK, et al. Sentinel lymph node mapping and molecular staging in non-small cell lung carcinoma. Cancer 2005;104:1453-1461.
152. Schnidt FE, Woltering EA, Webb WR, et al. Sentinel nodal assessment in patients with carcinoma of the lung. Ann Thorac Surg 2002;74:870-874.
153. Sugi K, Fukuda M, Nakamura H, Kaneda Y. Comparison of three tracers for detection sentinel lymph nodes in patients with clinical N0 lung cancer. Lung Cancer 2003;39:37-40.
154. Tiffet O, Nicholson A, Khaddage A, et al. Feasibility of the detection of the sentinel lymph node in peripheral non-small cell lung cancer with radio isotopic and blue dye techniques. Chest 2005;127:443-448.
155. Yoshimasu T, Miyoshi S, Oura S, et al. Limited mediastinal lymph node dissection for non-small cell lung cancer according to intraoperative histologic examinations. J Thorac Cardiovasc Surg 2005;130:241-242.
156. Niikura H, Okamura C, Utsunomiya H, et al. Sentinel lymph node detection in patients with endometrial cancer. Gynecol Oncol 2005;92:669-674.
157. Di Stefano AB, Acquaviva G, Garozzo G, et al. Lymph node mapping and sentinel node detection in patients with cervical carcinoma: a 2-year experience. Gynecol Oncol 2005;99:671-679.
158. Dhar KK, Woolas RP. Lymphatic mapping and sentinel node biopsy in early vulvar cancer. BJOG 2005;112:696-702.
159. Wawroschek F. Prostate lymphoscintigraphy and radio-guided surgery for sentinel node identification in prostate cancer. Urol Int 2003;70:303-310.
160. Liedberg F, Chebil G, Davidsson T, et al. Intraoperative sentinel node detection improves nodal staging in invasive bladder cancer. J Urol 2006;175:84-88.