One-pot cyclization of carbon nucleophiles with 2- isothiocyanatobenzonitrile (ITCB): Synthesis of 4-alkylidene-3,4- dihydroquinazoline-2(1H)thiones

Synthesis

Volumn , Issue 18, 2006, Pages 3067-3074

  Albrecht, Uwe ^a   Reinke, Helmut ^b   Langer, Peter ^b  

^a UNIVERSITY OF GREIFSWALD   (Germany)

^b UNIVERSITY OF ROSTOCK   (Germany)

Author keywords

Cyclizations; Heterocycles; Isothiocyanates; One pot reactions

Indexed keywords

HETEROCYCLES; ISOTHIOCYANATES; ONE POT REACTIONS; THIONES;

AROMATIC COMPOUNDS; AROMATIZATION; OLEFINS; REACTION KINETICS; STEREOCHEMISTRY; SYNTHESIS (CHEMICAL);

NITROGEN COMPOUNDS;

2 [1 CYANO 1 (4 TOLYL)]METHYLIDENE 3,4 DIHYDROQUINAZOLINE 2(1H)THIONE; 2 [1,2 DIHYDRO 2 OXOQUINAZOLIN 4(1H)YLIDENE]CYCLOHEXANE 1,3 DIONE; 2 ISOTHIOCYANATOBENZONITRILE; 2 N 2 (CYANO 1 (METHYLTHIO) 2 (4 METHOXYPHENYL)VINYL N (METHYLAMINO)BENZONITRILE; 2 N 2 CYANO 1 (METHYLTHIO) 2 (2 METHOXYPHENYL)VINYL N (METHYLAMINO)BENZONITRILE; 2 N 2 CYANO 1 (METHYLTHIO) 2 (2 TOLYL)VINYL N (METHYLAMINO)BENZONITRILE; 2 N 2 CYANO 1 (METHYLTHIO) 2 (4 TOLYL)VINYL N (METHYLAMINO)BENZONITRILE; 2 N [2 CYANO 1 (THIOMETHYL) 2 PHENYL]VINYL N (METHYLAMINO)BENZONITRILE; 4 (1 CYANO 1 PHENYL)METHYLIDENE 3,4 DIHYDROQUINAZOLINE 2(1H)THIONE; 4 [1 CYANO 1 (3 METHOXYPHENYL)]METHYLIDENE 3,4 DIHYDROQUINAZOLINE 2(1H)THIONE; 4 [1 CYANO 1 (3 TOLYL)]METHYLIDENE 3,4 DIHYDROQUINAZOLINE 2(1H)THIONE; 4 [1 CYANO 1 (4 BROMPHENYL)]METHYLIDENE 3,4 DIHYDROQUINAZOLINE 2(1H)THIONE; 4 [1 CYANO 1 (4 CYANOMETHYLPHENYL)]METHYLIDENE 3,4 DIHYROQUINAZOLINE 2(1H)THIONE; 4 [1 CYANO 1 (4 METHOXYPHENYL)]METHYLIDENE 3,4 DIHYDROQUINAZOLINE 2(1H)THIONE; 4 [1,2 DIHYDRO 2 THIOXOQUINAZOLIN 2(1H)YLIDENE] 5,5 DIMETHYLCYCLOHEXANE 1,3 DIONE; 4 [1,2 DIHYDRO 2 THIOXOQUINAZOLIN 2(1H)YLIDENE]CYCLOHEXANE 1,3 DIONE; 4 ALKYLIDENE 3,4 DIHYDROQUINAZOLINE 2(1H)THIONE; ANTINEOPLASTIC AGENT; BENZONITRILE; QUINAZOLINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACILLUS SUBTILIS; CARBON NUCLEAR MAGNETIC RESONANCE; CRYSTAL STRUCTURE; CYCLIZATION; DIASTEREOISOMER; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROGEN BOND; NUCLEAR MAGNETIC RESONANCE; PROTON NUCLEAR MAGNETIC RESONANCE; STAPHYLOCOCCUS AUREUS; STRUCTURE ACTIVITY RELATION;

EID: 33749517362     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2006-950182     Document Type: Article

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