Effect of high-dose intravenous dexamethasone on postlumbar discectomy pain

Spine

Volumn 31, Issue 21, 2006, Pages 2415-2417

  Aminmansour, Bahram ^a   Khalili, Hossein A ^a,b   Ahmadi, Jalal ^a   Nourian, Mahmood ^a  

^a ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b Kashani Hospital   (Iran)

Author keywords

Corticosteroids; Dexamethasone; Lumbar disc herniation; Lumbar discectomy

Indexed keywords

ANALGESIC AGENT; ANTIBIOTIC AGENT; DEXAMETHASONE; MORPHINE SULFATE; NARCOTIC AGENT; PLACEBO; RANITIDINE;

ADULT; ANALYSIS OF VARIANCE; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DATA ANALYSIS; DOSE RESPONSE; DRUG EFFECT; DRUG EFFICACY; DRUG MEGADOSE; EVALUATION; FEMALE; HOSPITAL ADMISSION; HUMAN; INFLAMMATION; LOW BACK PAIN; MALE; NERVE ROOT INFLAMMATION; OUTCOME ASSESSMENT; POSTOPERATIVE COMPLICATION; POSTOPERATIVE PAIN; POSTOPERATIVE PERIOD; PREOPERATIVE PERIOD; PRIORITY JOURNAL; PROSPECTIVE STUDY; RADICULAR PAIN; RANDOMIZED CONTROLLED TRIAL; SKIN INCISION; TRIPLE BLIND PROCEDURE; VISUAL ANALOG SCALE; WOUND INFECTION;

ADULT; DEXAMETHASONE; DISKECTOMY; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; FEMALE; HUMANS; INJECTIONS, INTRAVENOUS; INTERVERTEBRAL DISK DISPLACEMENT; LUMBAR VERTEBRAE; MALE; MIDDLE AGED; PAIN; PAIN MEASUREMENT; PAIN, POSTOPERATIVE; PROSPECTIVE STUDIES;

EID: 33749512837     PISSN: 03622436     EISSN: 15281159     Source Type: Journal    
DOI: 10.1097/01.brs.0000238668.49035.19     Document Type: Article

References (17)

1. Govind J. Lumbar radicular pain. Aust Fam Physician 2004;33:409-12.
2. Debi R, Halperin N, Mirovsky Y. Local application of steroids following lumbar discectomy. J Spinal Disord Tech 2002;15:273-6.
3. Ng LC, Sell P. Outcomes of a prospective cohort study on peri-radicular infiltration for radicular pain in patients with lumbar disc herniation and spinal stenosis. Eur Spine J 2004;13:325-9.
4. Karst M, Kegel T, Lukas A, et al. Effect of celecoxib and dexamethasone on postoperative pain after lumbar disc surgery. Neurosurgery 2003;53:331-7.
5. Lundin A, Magnuson A, Axelsson K, et al. The effect of perioperative corticosteroids on the outcome of microscopic lumbar disc surgery. Eur Spine J 2003;12:625-30.
6. King JS. Dexamethasone - A helpful adjunct in management after lumbar discectomy. Neurosurgery 1984;14:697-700.
7. Langmayr JJ, Obwegeser AA, Schwarz AB, et al. Intrathecal steroids to reduce pain after lumbar disc surgery: A double-blind, placebo-controlled prospective study. Pain 1995;62:357-61.
8. Manniche C, Lauritsen B, Vinterberg H. Peroperative prednisolone fails to improve the clinical outcome following surgery for prolapsed lumbar intervertebral disc. A randomized controlled trial. Scand J Rheumatol 1994;23: 30-5.
9. Lavyne MH, Bilsky MH. Epidural steroids, postoperative morbidity, and recovery in patients undergoing microsurgical lumbar discectomy. J Neurosurg 1992;77:90-5.
10. Lowell TD, Errico TJ, Eskenazi MS. Use of epidural steroids after discectomy may predispose to infection. Spine 2000;25:516-9.
11. Orpen NM, Birch NC. Delayed presentation of septic arthritis of a lumbar facet joint after diagnostic facet joint injection. J Spinal Disord Tech 2003;16:285-7.
12. Yue WM, Tan SB. Distant skip level discitis and vertebral osteomyelitis after caudal epidural injection: A case report of a rare complication of epidural injections. Spine 2003;28:E209-11.
13. Watters WC III, Temple AP, Granberry M. The use of dexamethasone in primary lumbar disc surgery. A prospective, randomized, double-blind study. Spine 1989;14:440-2.
14. Mirzai H, Tekin I, Alincak H. Perioperative use of corticosteroid and bupivacaine combination in lumbar disc surgery: A randomized controlled trial. Spine 2002;27:343-6.
15. Olmarker K, Byrod G, Cornefjord M, et al. Effects of methylprednisolone on nucleus pulposus-induced nerve root injury. Spine 1994;19:1803-8.
16. Glasser RS, Knego RS, Delashaw JB, et al. The perioperative use of corticosteroids and bupivacaine in the management of lumbar disc disease. J Neurosurg 1993;78:383-7.
17. Naylor A, Flowers MW, Bramley JE. The value of dexamethasone in the postoperative treatment of lumbar disc prolapse. Orthop Clin North Am 1977;8:3-8.