-
1
-
-
10044241785
-
Engineered biosynthesis of polyketides in heterologous hosts
-
Rude MA, Khosla C. Engineered biosynthesis of polyketides in heterologous hosts. Chem Eng Sci 59: 4693-4701 (2004)
-
(2004)
Chem Eng Sci
, vol.59
, pp. 4693-4701
-
-
Rude, M.A.1
Khosla, C.2
-
2
-
-
0035793858
-
Biosynthesis of complex polyketides in a metabolically engineered strain of E-coli
-
Pfeifer BA, Admiraal SJ, Gramajo H, Cane DE, Khosla C. Biosynthesis of complex polyketides in a metabolically engineered strain of E-coli. Science 291: 1790-1792 (2001)
-
(2001)
Science
, vol.291
, pp. 1790-1792
-
-
Pfeifer, B.A.1
Admiraal, S.J.2
Gramajo, H.3
Cane, D.E.4
Khosla, C.5
-
3
-
-
0015802957
-
Ansamycins, new class of microbial metabolites
-
Prelog V, Oppolzer W. Ansamycins, new class of microbial metabolites. Helv Chim Acta 56: 2279-2287 (1973)
-
(1973)
Helv Chim Acta
, vol.56
, pp. 2279-2287
-
-
Prelog, V.1
Oppolzer, W.2
-
4
-
-
0033376447
-
Intermediates of rifamycin polyketide synthase produced by an Amycolatopsis mediterranei mutant with inactivated rifF gene
-
Stratmann A, Toupet C, Schilling W, Traber R, Oberer L, Schupp T. Intermediates of rifamycin polyketide synthase produced by an Amycolatopsis mediterranei mutant with inactivated rifF gene. Microbiol-Uk 145: 3365-3375 (1999)
-
(1999)
Microbiol-Uk
, vol.145
, pp. 3365-3375
-
-
Stratmann, A.1
Toupet, C.2
Schilling, W.3
Traber, R.4
Oberer, L.5
Schupp, T.6
-
5
-
-
0032829914
-
Lessons from the rifamycin biosynthetic gene cluster
-
Floss HG, Yu TW. Lessons from the rifamycin biosynthetic gene cluster. Curr Opin Chem Biol 3: 592-597 (1999)
-
(1999)
Curr Opin Chem Biol
, vol.3
, pp. 592-597
-
-
Floss, H.G.1
Yu, T.W.2
-
6
-
-
13144258781
-
Biosynthesis of the ansamycin antibiotic rifamycin: Deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699
-
August PR, Tang L, Yoon YJ, Ning S, Mèuller R, Yu TW, Taylor M, Hoffmann D, Kim CG, Zhang X, Hutchinson CR, Floss HG. Biosynthesis of the ansamycin antibiotic rifamycin: deductions from the molecular analysis of the rif biosynthetic gene cluster of Amycolatopsis mediterranei S699. Chem Biol 5: 69-79 (1998)
-
(1998)
Chem Biol
, vol.5
, pp. 69-79
-
-
August, P.R.1
Tang, L.2
Yoon, Y.J.3
Ning, S.4
Mèuller, R.5
Yu, T.W.6
Taylor, M.7
Hoffmann, D.8
Kim, C.G.9
Zhang, X.10
Hutchinson, C.R.11
Floss, H.G.12
-
7
-
-
0037469308
-
Cloning and characterization of a gene cluster for geldanamycin production in Streptomyces hygroscopicus NRRL 3602
-
Rascher A, Hu Z, Viswanathan N, Schirmer A, Reid R, Nierman WC, Lewis M, Hutchinson CR. Cloning and characterization of a gene cluster for geldanamycin production in Streptomyces hygroscopicus NRRL 3602. FEMS Microbiol Lett 218: 223-230 (2003)
-
(2003)
FEMS Microbiol Lett
, vol.218
, pp. 223-230
-
-
Rascher, A.1
Hu, Z.2
Viswanathan, N.3
Schirmer, A.4
Reid, R.5
Nierman, W.C.6
Lewis, M.7
Hutchinson, C.R.8
-
8
-
-
0037062404
-
The biosynthetic gene cluster of the maytansinoid antitumor agent ansamitocin from Actinosynnema pretiosum
-
Yu TW, Bai L, Clade D, Hoffmann D, Toelzer S, Trinh KQ, Xu J, Moss SJ, Leistner E, Floss HG. The biosynthetic gene cluster of the maytansinoid antitumor agent ansamitocin from Actinosynnema pretiosum. Proc Natl Acad Sci USA 99: 7968-7973 (2002)
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 7968-7973
-
-
Yu, T.W.1
Bai, L.2
Clade, D.3
Hoffmann, D.4
Toelzer, S.5
Trinh, K.Q.6
Xu, J.7
Moss, S.J.8
Leistner, E.9
Floss, H.G.10
-
9
-
-
0037165707
-
Identification of a set of genes involved in the formation of the substrate for the incorporation of the unusual "glycolate" chain extension unit in ansamitocin biosynthesis
-
Carroll BJ, Moss SJ, Bai L, Kato Y, Toelzer S, Yu TW, Floss HG. Identification of a set of genes involved in the formation of the substrate for the incorporation of the unusual "glycolate" chain extension unit in ansamitocin biosynthesis. J Am Chem Soc 124: 4176-4177 (2002)
-
(2002)
J Am Chem Soc
, vol.124
, pp. 4176-4177
-
-
Carroll, B.J.1
Moss, S.J.2
Bai, L.3
Kato, Y.4
Toelzer, S.5
Yu, T.W.6
Floss, H.G.7
-
10
-
-
0041691117
-
Engineered biosynthesis of an ansamycin polyketide precursor in Escherichia coli
-
Watanabe K, Rude MA, Walsh CT, Khosla C. Engineered biosynthesis of an ansamycin polyketide precursor in Escherichia coli. Proc Natl Acad Sci USA 100: 9774-9778 (2003)
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 9774-9778
-
-
Watanabe, K.1
Rude, M.A.2
Walsh, C.T.3
Khosla, C.4
-
11
-
-
0034213759
-
Purification and biochemical properties of an N-hydroxyarylamine O-acetyltransferase from Escherichia coli
-
Yamamura E, Sayama M, Kakikawa M, Mon M, Taketo A, Kodaira K. Purification and biochemical properties of an N-hydroxyarylamine O-acetyltransferase from Escherichia coli. Biochim Biophys Acta 1475: 10-16 (2000)
-
(2000)
Biochim Biophys Acta
, vol.1475
, pp. 10-16
-
-
Yamamura, E.1
Sayama, M.2
Kakikawa, M.3
Mon, M.4
Taketo, A.5
Kodaira, K.6
-
12
-
-
0030780183
-
Glycyrrhizic acid inhibits arylamine N-acetyltransferase activity in Klebsiella pneumoniae in vitro
-
Lo HH, Yen YS, Hsieh SE, Chung JG. Glycyrrhizic acid inhibits arylamine N-acetyltransferase activity in Klebsiella pneumoniae in vitro. J Appl Toxicol 17: 385-390 (1997)
-
(1997)
J Appl Toxicol
, vol.17
, pp. 385-390
-
-
Lo, H.H.1
Yen, Y.S.2
Hsieh, S.E.3
Chung, J.G.4
-
13
-
-
0035996736
-
Expression and purification of the rifamycin amide synthase, RifF, an enzyme homologous to the prokaryotic arylamine N-acetyltransferases
-
Pompeo F, Mushtaq A, Sim E. Expression and purification of the rifamycin amide synthase, RifF, an enzyme homologous to the prokaryotic arylamine N-acetyltransferases. Prot Expr Purif 24: 138-151 (2002)
-
(2002)
Prot Expr Purif
, vol.24
, pp. 138-151
-
-
Pompeo, F.1
Mushtaq, A.2
Sim, E.3
-
14
-
-
0242663236
-
Crystal structure of an Acyl-ACP dehydrogenase from the FK520 polyketide biosynthetic pathway: Insights into extender unit biosynthesis
-
Watanabe K, Khosla C, Stroud RM, Tsai SC. Crystal structure of an Acyl-ACP dehydrogenase from the FK520 polyketide biosynthetic pathway: insights into extender unit biosynthesis. J Mol Biol 334: 435-444 (2003)
-
(2003)
J Mol Biol
, vol.334
, pp. 435-444
-
-
Watanabe, K.1
Khosla, C.2
Stroud, R.M.3
Tsai, S.C.4
-
15
-
-
5444268703
-
Engineered biosynthesis of 16-membered macrolides that require methoxymalonyl-ACP precursors in Streptomyces fradiae
-
Rodriguez E, Ward S, Fu H, Revill WP, McDaniel R, Katz L. Engineered biosynthesis of 16-membered macrolides that require methoxymalonyl-ACP precursors in Streptomyces fradiae. Appl Microbiol Biotechnol 66: 85-91 (2004)
-
(2004)
Appl Microbiol Biotechnol
, vol.66
, pp. 85-91
-
-
Rodriguez, E.1
Ward, S.2
Fu, H.3
Revill, W.P.4
McDaniel, R.5
Katz, L.6
-
16
-
-
23844467713
-
Stereochemical assignment of intermediates in the rifamycin biosynthetic pathway by precursor-directed biosynthesis
-
Hartung IV, Rude MA, Schnarr NA, Hunziker D, Khosla C. Stereochemical assignment of intermediates in the rifamycin biosynthetic pathway by precursor-directed biosynthesis. J Am Chem Soc 127: 11202-11203 (2005)
-
(2005)
J Am Chem Soc
, vol.127
, pp. 11202-11203
-
-
Hartung, I.V.1
Rude, M.A.2
Schnarr, N.A.3
Hunziker, D.4
Khosla, C.5
-
17
-
-
0024340114
-
New method for generating deletions and gene replacements in Escherichia coli
-
Hamilton CM, Aldea M, Washburn BK, Babitzke P, Kushner SR. New method for generating deletions and gene replacements in Escherichia coli. J Bacteriol 171: 4617-4622 (1989)
-
(1989)
J Bacteriol
, vol.171
, pp. 4617-4622
-
-
Hamilton, C.M.1
Aldea, M.2
Washburn, B.K.3
Babitzke, P.4
Kushner, S.R.5
|