Montelukast in allergic rhinitis: A systematic review and meta-analysis

Clinical Otolaryngology

Volumn 31, Issue 5, 2006, Pages 360-367

  Grainger, J ^a   Drake Lee, A ^a  

^a QUEEN ELIZABETH HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIHISTAMINIC AGENT; CORTICOSTEROID; FEXOFENADINE; FLUTICASONE PROPIONATE; LEUKOTRIENE RECEPTOR BLOCKING AGENT; LORATADINE; MONTELUKAST; PSEUDOEPHEDRINE; STEROID; ZAFIRLUKAST;

ALLERGIC RHINITIS; CLINICAL TRIAL; CONFIDENCE INTERVAL; DRUG EFFICACY; HUMAN; MEDICAL PRACTICE; MEDICAL RESEARCH; META ANALYSIS; PRIORITY JOURNAL; REVIEW; SCORING SYSTEM; SYMPTOM; SYSTEMATIC REVIEW; TREATMENT RESPONSE;

ACETATES; ADRENAL CORTEX HORMONES; CLINICAL TRIALS; DRUG THERAPY, COMBINATION; HISTAMINE H1 ANTAGONISTS; HUMANS; LEUKOTRIENE ANTAGONISTS; QUALITY OF LIFE; QUESTIONNAIRES; QUINOLINES; RHINITIS, ALLERGIC, PERENNIAL; TREATMENT OUTCOME;

EID: 33749452692     PISSN: 17494478     EISSN: 17494486     Source Type: Journal    
DOI: 10.1111/j.1749-4486.2006.01276.x     Document Type: Review

References (55)

1. Richards S., Thornhill D., Roberts H. et al. (1992) How many people think they have hay fever, and what they do about it. Br. J. Gen. Pract. 42, 284-286
2. Gupta R., Sheikh A., Strachan D.P. et al. (2004) Burden of allergic disease in the UK: secondary analyses of national databases. Clin. Exp. Allergy 34, 520-526
3. Jones N.S., Smith P.A., Carney A.S. et al. (1998) The prevalence of allergic rhinitis and nasal symptoms in Nottingham. Clin. Otolaryngol. Allied. Sci. 23, 547-554
4. Sibbald B. & Rink E. (1991) Epidemiology of seasonal and perennial rhinitis: clinical presentation and medical history. Thorax 46, 895-901
5. Stuck B.A., Czajkowski J., Hagner A.E. et al. (2004) Changes in daytime sleepiness, quality of life, and objective sleep patterns in seasonal allergic rhinitis: a controlled clinical trial. J. Allergy. Clin. Immunol. 113, 663-668
6. van Cauwenberge C.P., Bachert C., Passalacqua G. et al. (2000) Consensus statement on the treatment of allergic rhinitis. European Academy of Allergology and Clinical Immunology. Allergy 55, 116-134
7. Weiner J.M., Abramson M.J. & Puy R.M. (1998) Intranasal corticosteroids versus oral H1 receptor antagonists in allergic rhinitis: systematic review of randomised controlled trials. BMJ. 317, 1624-1629
8. Yanez A. & Rodrigo G.J. (2002) Intranasal corticosteroids versus topical H1 receptor antagonists for the treatment of allergic rhinitis: a systematic review with meta-analysis. Ann. Allergy Asthma. Immunol. 89, 479-484
9. Altman L.C., Munk Z., Seltzer J. et al. (1998) A placebo-controlled, dose-ranging study of montelukast, a cysteinyl leukotriene-receptor antagonist. Montelukast Asthma Study Group. J. Allergy Clin. Immunol 102, 50-56
10. Lofdahl C.G., Reiss T.F., Leff J.A. et al. (1999) Randomised, placebo controlled trial of effect of a leukotriene receptor antagonist, montelukast, on tapering inhaled corticosteroids in asthmatic patients. BMJ. 319, 87-90
11. Blaiss M.S. (2005) Rhinitis-asthma connection: epidemiologic and pathophysiologic basis. Allergy Asthma Proc. 26, 35-40
12. Meltzer E.O. (2005) The relationships of rhinitis and asthma. Allergy Asthma Proc. 26, 336-340
13. Nayak A.S. (2003) The asthma and allergic rhinitis link. Allergy Asthma Proc. 24, 395-402
14. Lipworth B.J. (1999) Leukotriene-receptor antagonists. Lancet 353, 57-62
15. Wilson A.M., O'Byrne P.M. & Parameswaran K. (2004) Leukotriene receptor antagonists for allergic rhinitis: a systematic review and meta-analysis. Am. J. Med. 116, 338-344
16. Juniper E.F. & Guyatt G.H. (1991) Development and testing of a new measure of health status for clinical trials in rhinoconjunctivitis. Clin. Exp. Allergy 21, 77-83
17. Chervinsky P., Philip G., Malice M.P. et al. (2004) Montelukast for treating fall allergic rhinitis: effect of pollen exposure in 3 studies. Ann. Allergy Asthma Immunol. 92, 367-373
18. Di L.G., Pacor M.L., Pellitteri M.E. et al. (2004) Randomized placebo-controlled trial comparing fluticasone aqueous nasal spray in mono-therapy, fluticasone plus cetirizine, fluticasone plus montelukast and cetirizine plus montelukast for seasonal allergic rhinitis. Clin. Exp. Allergy 34, 259-267
19. Kurowski M., Kuna P. & Gorski P. (2004) Montelukast plus cetirizine in the prophylactic treatment of seasonal allergic rhinitis: influence on clinical symptoms and nasal allergic inflammation. Allergy 59, 280-288
20. Lee D.K., Jackson C.M., Soutar P.C. et al. (2004) Effects of single or combined histamine H1-receptor and leukotriene Cys-LT1-receptor antagonism on nasal adenosine monophosphate challenge in persistent allergic rhinitis. Br. J. Clin. Pharmacol. 57, 714-719
21. Meltzer E.O., Malmstrom K., Lu S. et al. (2000) Concomitant montelukast and loratadine as treatment for seasonal allergic rhinitis: a randomized, placebo-controlled clinical trial. J. Allergy Clin. Immunol. 105, 917-922
22. Nathan R.A., Yancey S.W., Waitkus-Edwards K. et al. (2005) Fluticasone propionate nasal spray is superior to montelukast for allergic rhinitis while neither affects overall asthma control. Chest 128, 1910-1920
23. Nayak A.S., Philip G., Lu S. et al. (2002) Efficacy and tolerability of montelukast alone or in combination with loratadine in seasonal allergic rhinitis: a multicenter, randomized, double-blind, placebo-controlled trial performed in the fall. Ann. Allergy Asthma Immunol. 88, 592-600
24. Patel P., Philip G., Yang W. et al. (2005) Randomized, double-blind, placebo-controlled study of montelukast for treating perennial allergic rhinitis. Ann. Allergy Asthma Immunol. 95, 551-557
25. Philip G., Malmstrom K., Hampel F.C. et al. (2002) Montelukast for treating seasonal allergic rhinitis: a randomized, double-blind, placebo-controlled trial performed in the spring. Clin. Exp. Allergy 32, 1020-1028
26. Philip G., Nayak A.S., Berger W.E. et al. (2004) The effect of montelukast on rhinitis symptoms in patients with asthma and seasonal allergic rhinitis. Curr. Med. Res. Opin. 20, 1549-1558
27. Pullerits T., Praks L., Ristioja V. et al. (2002) Comparison of a nasal glucocorticoid, antileukotriene, and a combination of antileukotriene and antihistamine in the treatment of seasonal allergic rhinitis. J. Allergy Clin. Immunol. 109, 949-955
28. Ratner P.H., Howland W.C. III, Arastu R. et al. (2003) Fluticasone propionate aqueous nasal spray provided significantly greater improvement in daytime and nighttime nasal symptoms of seasonal allergic rhinitis compared with montelukast. Ann. Allergy Asthma Immunol. 90, 536-542
29. Saengpanich S., deTineo M., Naclerio R.M. et al. (2003) Fluticasone nasal spray and the combination of loratadine and montelukast in seasonal allergic rhinitis. Arch. Otolaryngol. Head. Neck. Surg. 129, 557-562
30. van Adelsberg J., Philip G., Pedinoff A.J. et al. (2003) Montelukast improves symptoms of seasonal allergic rhinitis over a 4-week treatment period. Allergy 58, 1268-1276
31. van Adelsberg J., Philip G., LaForce C.F. et al. (2003) Randomized controlled trial evaluating the clinical benefit of montelukast for treating spring seasonal allergic rhinitis. Ann. Allergy Asthma Immunol. 90, 214-222
32. Wilson A.M., Dempsey O.J., Sims E.J. et al. (2000) Evaluation of treatment response in patients with seasonal allergic rhinitis using domiciliary nasal peak inspiratory flow. Clin. Exp. Allergy 30, 833-838
33. Wilson A.M., Sims E.J., Orr L.C. et al. (2001) Effects of topical corticosteroid and combined mediator blockade on domiciliary and laboratory measurements of nasal function in seasonal allergic rhinitis. Ann. Allergy Asthma Immunol. 87, 344-349
34. Wilson A.M., Dempsey O.J., Sims E.J. et al. (2001) A comparison of topical budesonide and oral montelukast in seasonal allergic rhinitis and asthma. Clin. Exp. Allergy 31, 616-624
35. Wilson A.M., Orr L.C., Sims E.J. et al. (2001) Effects of monotherapy with intra-nasal corticosteroid or combined oral histamine and leukotriene receptor antagonists in seasonal allergic rhinitis. Clin. Exp. Allergy 31, 61-68
36. Wilson A.M., Orr L.C., Coutie W.J. et al. (2002) A comparison of once daily fexofenadine versus the combination of montelukast plus loratadine on domiciliary nasal peak flow and symptoms in seasonal allergic rhinitis. Clin. Exp. Allergy 32, 126-132
37. Bukstein D.A. (2003) Role of leukotriene receptor antagonists (LTRAs) in seasonal allergic rhinitis. Ann. Allergy Asthma Immunol. 91, 417-418
38. Jackson C.M. & Lipworth B.J. (2004) Combined mediator antagonism for allergic rhinitis. Allergy 59, 276-279
39. Kieff D.A. & Busaba N.Y. (2005) Efficacy of montelukast in the treatment of nasal polyposis. Ann. Otol. Rhinol. Laryngol. 114, 941-945
40. Kutting B., Nieschalk M. & Brehler R. (2000) A new concept for treatment of sinonasal polyposis. Allergy 55, 1091-1092
41. Nathan R.A. (2005) Leukotriene receptor antagonists are not as effective as intranasal corticosteroids for managing nighttime symptoms of allergic rhinitis. J. Allergy Clin. Immunol. 116, 463-464
42. Ragab S., Parikh A., Darby Y.C. et al. (2001) An open audit of montelukast, a leukotriene receptor antagonist, in nasal polyposis associated with asthma. Clin. Exp. Allergy 31, 1385-1391
43. Sander C. & Rajakulasingam K. (2002) Leukotriene receptor antagonists for the treatment of allergic rhinitis. Clin. Exp. Allergy 32, 4-7
44. Shahab R., Phillips D.E. & Jones A.S. (2004) Prostaglandins, leukotrienes and perennial rhinitis. J. Laryngol. Otol. 118, 500-507
45. Ulualp S.O., Sterman B.M. & Toohill R.J. (1999) Antileukotriene therapy for the relief of sinus symptoms in aspirin triad disease. Ear Nose Throat J. 78, 604-606, 608, 613, passim
46. Wilson A.M., White P.S., Gardiner Q. et al. (2001) Effects of leukotriene receptor antagonist therapy in patients with chronic rhinosinusitis in a real life rhinology clinic setting. Rhinology 39, 142-146
47. Ciprandi G., Tosca M.A., Milanese M. et al. (2004) Antihistamines added to an antileukotriene in treating seasonal allergic rhinitis: histamine and leukotriene antagonism. Allergy Immunol. (Paris) 36, 67-70, 72
48. Baena-Cagnani C.E., Berger W.E., DuBuske L.M. et al. (2003) Comparative effects of desloratadine versus montelukast on asthma symptoms and use of beta 2-agonists in patients with seasonal allergic rhinitis and asthma. Int. Arch. Allergy Immunol. 130, 307-313
49. Berges-Gimeno M.P., Simon R.A. & Stevenson D.D. (2002) The effect of leukotriene-modifier drugs on aspirin-induced asthma and rhinitis reactions. Clin. Exp. Allergy 32, 1491-1496
50. Malerba M., Radaeli A., Ceriani L. et al. (2002) Comparison of oral montelukast and inhaled fluticasone in the treatment of asthma associated with chronic rhinopolyposis: a single-blind, randomized, pilot study. Curr. Ther. Res. Clin. Exp. 63, 355-365
51. Parnes S.M. & Chuma A.V. (2000) Acute effects of antileukotrienes on sinonasal polyposis and sinusitis. Ear Nose Throat J. 79, 18-25
52. Pullerits T., Praks L., Skoogh B.E. et al. (1999) Randomized placebo-controlled study comparing a leukotriene receptor antagonist and a nasal glucocorticoid in seasonal allergic rhinitis. Am. J. Respir. Crit. Care Med. 159, 1814-1818
53. Moinuddin R., deTineo M., Maleckar B. et al. (2004) Comparison of the combinations of fexofenadine-pseudoephedrine and loratadine-montelukast in the treatment of seasonal allergic rhinitis. Ann. Allergy Asthma Immunol. 92, 73-79
54. Mostafa B.E., Abdel H.H., Mohammed H.E. et al. (2005) Role of leukotriene inhibitors in the postoperative management of nasal polyps. ORL J. Otorhinolaryngol. Relat. Spec. 67, 148-153
55. Lee D.K., Haggart K., Currie G.P. et al. (2003) The effects of histamine and leukotriene receptor antagonism on nasal mannitol challenge in allergic rhinitis. Br. J. Clin. Pharmacol. 55, 639-642