Nano- and microparticles as adjuvants in vaccine design: Success and failure is related to host natural antibodies

Vaccine

Volumn 24, Issue 42-43, 2006, Pages 6534-6541

  Sinyakov, Michael S ^a   Dror, Moti ^a   Lublin Tennenbaum, Tammy ^a   Salzberg, Samuel ^a   Margel, Shlomo ^a   Avtalion, Ramy R ^a  

^a BAR ILAN UNIVERSITY   (Israel)

Author keywords

Acquired antibodies; Aeromonas salmonicida; Natural antibodies

Indexed keywords

A LAYER PROTEIN; A LAYER PROTEIN ALUMINUM POTASSIUM SULFATE; A LAYER PROTEIN BOVINE SERUM ALBUMIN SEPHAROSE CONJUGATE; A LAYER PROTEIN INCOMPLETE FREUND ADJUVANT; A LAYER PROTEIN POLYACROLEIN CONJUGATE; A LAYER PROTEIN SEPHAROSE CONJUGATE; BOVINE SERUM ALBUMIN; BOVINE SERUM ALBUMIN ALUMINUM; BOVINE SERUM ALBUMIN INCOMPLETE FREUND ADJUVANT; BOVINE SERUM ALBUMIN POLYACROLEIN CONJUGATE; IMMUNOLOGICAL ADJUVANT; NANOPARTICLE; PROTEIN; UNCLASSIFIED DRUG;

AEROMONAS SALMONICIDA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY PRODUCTION; ANTIBODY RESPONSE; ANTIGENICITY; ARTICLE; BACTERIAL STRAIN; CELLULAR IMMUNITY; CONJUGATION; CONTROLLED STUDY; CORRELATION ANALYSIS; COVALENT BOND; FEMALE; GOLDFISH; IMMUNE RESPONSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; VACCINATION;

ACROLEIN; ADJUVANTS, IMMUNOLOGIC; AEROMONAS SALMONICIDA; ALUMINUM COMPOUNDS; ANIMALS; ANTIBODIES; ANTIGENS; ANTIGENS, BACTERIAL; CATTLE; CHEMISTRY, PHARMACEUTICAL; DRUG DESIGN; EMULSIONS; GOLDFISH; INDICATORS AND REAGENTS; MICE; MICE, INBRED BALB C; NANOPARTICLES; POLYMERS; SEPHAROSE; SERUM ALBUMIN, BOVINE; VACCINES;

EID: 33749446992     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2006.06.021     Document Type: Article

References (38)

1. Lovgren-Bengtsson K. Preparation and use of adjuvants. In: Kaufmann S.H.E., and Kabelitz D. (Eds). Methods in microbiology vol. 25 (1998), Academic Press, San Diego 471-502
2. Bomford R. Adjuvants for anti-parasite vaccines. Parasit Today 5 (1989) 41-46
3. Heath A.W., and Playfair J.H.L. Cytokines as immunological adjuvant. Vaccine 10 (1992) 427-434
4. Degling L., and Stjärnkvist P. Biodegradable microspheres. XVIII. The adjuvant effect of polyacryl starch microparticles with conjugated human serum albumin. Vaccine 13 (1995) 629-636
5. Langhein C., and Newman J.F. Antibody response to bacterial antigens covalently bound to biodegradable polymerized serum albumin beads. J Appl Bacteriol 63 (1987) 443-448
6. Andreev S.M., Sinyakov M.S., Norimov A.S., and Shikunova O.A. Immunogenic and protective activities of influenza virus haemagglutinin conjugated with synthetic polymer microspheres. Immunologiya [Moscow] 1 (1990) 36-38
7. Barrow E.L., Winchester G.A., Staas J.K., Quenelle D.C., and Barrow W.W. Use of microsphere technology for targeted delivery of rifampin to mycobacterium tuberculosis-infected macrophages. Antimicrob Agents Chemother 42 (1998) 2682-2689
8. Seong S.Y., Cho N.H., Kwon I.C., and Jeong S.Y. Protective immunity of microsphere-based mucosal vaccines against lethal intranasal challenge with streptococcus pneumoniae. Infect Immun 67 (1999) 3587-3592
9. Flick-Smith H.C., Eyles J.E., Hebdon R., Waters E.L., Beedham R.J., Stagg T.J., et al. Mucosal or parenteral administration of microsphere-associated bacillus anthracis protective antigen protects against anthrax infection in mice. Infect Immun 70 (2002) 2022-2028
10. Xie H., Gursel I., Ivins B.E., Singh M., O'Hagan D.T., Ulmer J.B., et al. CpG oligodeoxynucleotides adsorbed onto polylactide-co-glycolide microparticles improve the antigenicity and protective activity of the licensed anthrax vaccine. Infect Immun 73 (2005) 828-833
11. Degling L., Stjärnkvist P., and Sjöholm I. Interferon-γ in starch microparticles: nitric- oxide generating activity in vitro and antileishmanial effect in mice. Pharm Res 10 (1993) 783-790
12. Kovacsovics-Bankowski M., Clark K., Benacerraf B., and Rock K.L. Efficient major histocompatibility complex class I presentation of exogenous antigen upon phagocytosis by macrophages. Proc Natl Acad Sci USA 90 (1993) 4942-4946
13. + T cell responses by antigens covalently linked to synthetic microspheres does not require adjuvant. Int Immunol 7 (1995) 45-53
14. + T cell response induced by particulate antigen targeted to phagocytic cells. Int Immunol 9 (1997) 91-103
15. Kreuter J. Nanoparticles as potent adjuvants for vaccines. In: Gregoriadis G. (Ed). New generation vaccines (1993), Plenum Press, New York 73-81
16. Kreuter J. Nanoparticles and microparticles for drug and vaccine delivery. J Anat 189 (1996) 503-505
17. Callender D.P., Jayaprakash N., Bell A., Petraitis V., Petratienes R., Candelario M., et al. Pharmacokinetics of oral zidovudine entrapped in biodegradable nanospheres in rabbits. Antimicrob Agents Chemother 43 (1999) 972-974
18. Cui Z., and Mumper R.J. Microparticles and nanoparticles as delivery systems for DNA vaccines. Crit Rev Ther Drug Carrier Syst 20 (2003) 103-137
19. Vila A., Sanchez A., Evora C., Soriano I., Vila Jato J.L., and Alonso M.J. PEG-PLA nanoparticles as carriers for nasal vaccine delivery. J Aerosol Med 17 (2004) 174-185
20. Margel S., Burdygin I., Reznikov V., Nitzan B., Melamed O., Kedem M., et al. Functional nanospheres: synthesis and biological applications. Recent Res Dev Polym Sci 1 (1997) 51-78
21. Jani P., Halbert G.W., Langridge J., and Florence A.T. The uptake and translocation of latex nanospheres and microspheres after oral administration to rats. J Pharm Pharmacol 41 (1989) 809-812
22. Florence A.T., Hillery A.M., Hussain N., and Jani P.U. Factors affecting the oral uptake and translocation of polystyrene nanoparticles: histological and analytical evidence. J Drug Target 3 (1995) 65-70
23. Austin B., and Adams C. Fish pathogens. In: Austin B., Altwegg M., Gosling P.J., and Joseph S. (Eds). The genus aeromonas (1996), Wiley, New York 197-243
24. Kay W.W., Buckley J.T., Ishiguro E.E., Phipps B.M., Monette J.P.L., and Trust T.J. Purification and disposition of a surface protein associated with virulence of Aeromonas salmonicida. J Bacteriol 147 (1981) 1077-1084
25. Austin B. Progress in understanding the fish pathogen Aeromonas salmonicida. Trends Biotechnol 15 (1997) 131-134
26. Margel S, Gura S. Nucleation and growth of magnetic metal oxide nanoparticles of controlled size distribution and its use. American Patent Application No. 09/084, 726 (1998).
27. Margel S. Characterization and chemistry of polyaldehyde microspheres. J Polym Sci Chem Ed 22 (1984) 3521-3533
28. Markwell M.A.K., Haas S.M., Bieber L.L., and Tolbert N.E. A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples. Anal Biochem 87 (1978) 206-210
29. Sinyakov M.S., Dror M., Zhevelev H.M., Margel S., and Avtalion R.R. Natural antibodies and their significance in active immunization and protection against a defined pathogen in fish. Vaccine 20 (2002) 3668-3674
30. Dror M., Sinyakov M.S., Okun E., Dym M., Sredni B., and Avtalion R.R. Experimental handling stress as infection-facilitating factor for the goldfish ulcerative disease. Vet Immunol Immunopathol 109 (2006) 279-287
31. Scales R.W., Jacobs Jr. N.F., and Skaggs R. Use of immunoglobulin coupled to agarose beads for examining the specificity of conjugates. J Clin Microbiol 2 (1975) 292-295
32. Porath J., and Axén R. Immobilization of enzymes to agar, agarose and sephadex supports. Meth Enzymol 44 (1976) 19-45
33. Grönlund H., Vrtala S., Wiedermann U., Dekan G., Kraft D., Valenta R., et al. Carbohydrate-based particles: a new adjuvant for allergen-specific immunotherapy. Immunology 107 (2002) 523-529
34. Avtalion R.R. Environmental control of the immune response in fish. CRC Crit Rev Environ Contr 11 (1981) 163-188
35. Fearon D.T., and Locksley R. The instructive role of innate immunity in the acquired immune response. Science 272 (1996) 50-54
36. Boes M. Role of natural and immune IgM antibodies in immune responses. Mol Immunol 37 (2000) 1141-1149
37. Magnadóttir B. Innate immunity of fish (overview). Fish Shellfish Immunol 20 (2006) 137-151
38. Nagabhushanam V., Solache A., Ting L.M., Escaron C.J., Zhang J.Y., and Ernst J.D. Innate inhibition of adaptive immunity: mycobacterium tuberculosis-induced IL-6 inhibits macrophage responses to IFN-gamma. J Immunol 171 (2003) 4750-4757