Markers for endothelial dysfunction, but not markers for oxidative stress correlate with classical risk factors and the severity of coronary artery disease

Scandinavian Cardiovascular Journal

Volumn 40, Issue 5, 2006, Pages 274-279

  Ruef, Johannes ^a   Márz, Winfried ^b   Winkelmann, Bernhard R ^c  

^a Red Cross Hospital Cardiology Center   (Germany)

^b SYNLAB ACADEMY   (Germany)

^c Clinical Research Institute   (Germany)

Author keywords

Atherosclerosis; Coronary artery disease; Endothelial dysfunction; Oxidative stress; Plasma markers

Indexed keywords

8 ISOPROSTANE; ACETYLSALICYLIC ACID; ANGIOTENSIN RECEPTOR ANTAGONIST; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BIOLOGICAL MARKER; C REACTIVE PROTEIN; CALCIUM ANTAGONIST; CHOLESTEROL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; GLUTATHIONE; GLUTATHIONE PEROXIDASE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; HOMOCYSTEINE; INSULIN; INTERCELLULAR ADHESION MOLECULE 1; L SELECTIN; LIPID PEROXIDE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MYELOPEROXIDASE; NITRIC OXIDE; PADGEM PROTEIN; SUPEROXIDE DISMUTASE; THROMBOMODULIN; TRIACYLGLYCEROL; VASCULAR CELL ADHESION MOLECULE 1; VON WILLEBRAND FACTOR;

ACUTE CORONARY SYNDROME; ADULT; AGED; ANTIOXIDANT ACTIVITY; ARTICLE; ATHEROGENESIS; BLOOD SAMPLING; CASE CONTROL STUDY; CIGARETTE SMOKING; CONTROLLED STUDY; CORONARY ARTERY DISEASE; CORONARY RISK; CORRELATION ANALYSIS; DIABETES MELLITUS; DIAGNOSTIC VALUE; DISEASE ASSOCIATION; DISEASE CLASSIFICATION; DISEASE SEVERITY; ENDOTHELIAL DYSFUNCTION; ENZYME ANALYSIS; FEMALE; HUMAN; HYPERTENSION; MAJOR CLINICAL STUDY; MALE; OXIDATIVE STRESS; PREDICTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; RISK ASSESSMENT; RISK FACTOR; STABLE ANGINA PECTORIS; VASCULAR DISEASE;

ADULT; AGED; BIOLOGICAL MARKERS; CORONARY ARTERIOSCLEROSIS; CORONARY ARTERY DISEASE; DATA INTERPRETATION, STATISTICAL; DIABETES MELLITUS; ENDOTHELIUM, VASCULAR; FEMALE; HEALTH SURVEYS; HUMANS; MALE; MIDDLE AGED; OXIDATIVE STRESS; RISK FACTORS;

EID: 33749419349     PISSN: 14017431     EISSN: 16512006     Source Type: Journal    
DOI: 10.1080/14017430600925300     Document Type: Article

References (20)

1. Forgione, MA and Leopold, JA and Loscalzo, J. (2000) Roles of endothelial dysfunction in coronary artery disease Curr Opin Cardiol., 15, pp. 409-15.
2. Ruef, J and Peter, K and Nordt, TK and Runge, MS and Kubler, W and Bode, C. (1999) Oxidative stress and atherosclerosis: Its relationship to growth factors, thrombus formation and therapeutic approaches Thromb Heamost., 82(Suppl 1), pp. 32-7.
3. Ridker, PM and Brown, NJ and Vaughan, DE and Harrison, DG and Mehta, JL. (2004) Established and emerging plasma biomarkers in the prediction of first atherothrombotic events Circulation., 109(Suppl IV), pp. IV6-IV19.
4. Winkelmann, BR and März, W and Boehm, BO and Zotz, R and Hager, J and Hellstern, P and (2001) Rationale and design of the LURIC study -a resource for functional genomics, pharmacogenomics and long-term prognosis of cardiovascular disease Pharmacogenomics., 2, pp. S1-73.
5. März, W and Winker, K and Nauck, M and Böhm, BO and Winkelmann, BR. (2003) Effects of statins on C-reactive protein and interleukin-6 (the Ludwigsafen Risk and Cardiovascular Health Study) Am J Cardiol., 92, pp. 305-8.
6. Ridker, PM. (2003) Clinical application of C-reactive protein for cardiovascular disease detection and prevention Circulation., 107, pp. 363-9.
7. Malik, I and Danesh, J and Whincup, P and Bhatia, V and Papacosta, O and Walker, M and (2001) Soluble adhesion molecules and prediction of coronary heart disease: A prospective study and meta-analysis Lancet., 358, pp. 971-6.
8. Blann, AD and McCollum, CN and Lip, GYH. (2002) Relationship between plasma markers of endothelial cell integrity and the Framingham cardiovascular disease risk factor scores in apparently healthy individuals Blood Coagul Fibrinolysis., 13, pp. 513-8.
9. Torres, JL and Ridker, PM. (2003) Clinical use of high-sensitive C-reactive protein for the prediction of adverse cardiovascular events Curr Opin Cardiol., 18, pp. 471-8.
10. Ridker, PM and Buring, JE and Rifai, N. (2001) Soluble P-selectin and the risk of future cardiovascular events Circulation., 103, pp. 491-5.
11. Ridker, PM and Hennekens, CH and Roitman-Johnson, B and Stanpfer, MJ and Allen, J. (1998) Plasma concentration of soluble intercellular adhesion molecule 1 and risks of future myocardial infarction in apparently healthy men Lancet., 351, pp. 88-92.
12. Hope, SA and Meredith, IT. (2003) Cellular adhesion molecules and cardiovascular disease. Part II. Their association with conventional and emerging risk factors, acute coronary events and cardiovascular risk prediction Intern Med J., 33, pp. 450-62.
13. Kurita, A and Matsui, T and Ishizuka, T and Takase, B and Satomura, K. (2005) Significance of plasma nitric oxide/endothelin-1 ratio for prediction of coronary artery disease Angiology., 56, pp. 259-64.
14. Haught, WH and Mansour, M and Rothlein, R and Kishimoto, TK and Mainolfi, EA and Hendricks, JB and (1996) Alterations in circulating intercellular adhesion molecule-1 and L-selectin: Further evidence for chronic inflammation in ischemic heart disease Am Heart J., 132, pp. 1-8.
15. Albertini, JP and Valensi, P and Lormeau, B and Vaysse, J and Attali, JR and Gattegno, L. (1999) Soluble L-selectin level is a marker for coronary artery disease in type 2 diabetic patients Diabetes Care., 22, pp. 2044-8.
16. Kaneda, H and Taguchi, J and Ogasawara, K and Aizawa, T and Ohno, M. (2002) Increased levels of advanced oxidation protein products in patients with coronary artery disease Atherosclerosis., 162, pp. 221-5.
17. Kostner, K and Hornykewycz, S and Yang, P and Neuntreufl, T and Glogar, D and Weidinger, F and (1997) Is oxidative stress causally liked to unstable angina pectoris? A study in 100 CAD patients and matched controls Cardiovasc Res., 36, pp. 330-6.
18. Zhang, R and Brennan, ML and Fu, X and Aviles, RJ and Pearce, GL and Penn, MS and (2001) Association between myeloperoxidase levels and risk of coronary artery disease JAMA., 286, pp. 2136-42.
19. Brennan, ML and Penn, MS and Van Lente, F and Nambi, V and Shishehbor, MH and Aviles, RJ and (2003) Prognostic value of myeloperoxidase in patients with chest pain N Engl J Med., 349, pp. 1595-604.
20. Loeper, J and Goy, J and Klein, JM and Dufour, M and Bedu, O and Loeper, S and (1991) The evolution of oxidative stress indicators in the course of myocardial infarction Free Radic Res Commun., 12-13, pp. 675-80.