Being specific about race-specific medicine: Physicians should be able to prescribe BiDil, if it is appropriate, to any patient, regardless of race

Health Affairs

Volumn 25, Issue 5, 2006, Pages

  Kahn, Jonathan ^a   Sankar, Pamela ^b  

^a HAMLINE UNIVERSITY   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HYDRALAZINE; HYDRALAZINE PLUS ISOSORBIDE DINITRATE; ISOSORBIDE DINITRATE; ISOSORBIDE HYDRALAZINE COMBINATION; ISOSORBIDE-HYDRALAZINE COMBINATION; VASODILATOR AGENT;

AFRICAN AMERICAN; CONGESTIVE HEART FAILURE; DRUG APPROVAL; DRUG COMBINATION; DRUG INDUSTRY; ETHNOLOGY; FOOD AND DRUG ADMINISTRATION; GENETIC PREDISPOSITION; GENETICS; HEART FAILURE; HUMAN; RISK; SHORT SURVEY; UNITED STATES;

AFRICAN AMERICANS; DRUG APPROVAL; DRUG COMBINATIONS; DRUG INDUSTRY; GENETIC PREDISPOSITION TO DISEASE; HEART FAILURE; HEART FAILURE, CONGESTIVE; HUMANS; HYDRALAZINE; ISOSORBIDE DINITRATE; RISK; UNITED STATES; UNITED STATES FOOD AND DRUG ADMINISTRATION; VASODILATOR AGENTS;

EID: 33749352359     PISSN: 02782715     EISSN: 02782715     Source Type: Journal    
DOI: 10.1377/hlthaff.25.w375     Document Type: Short Survey

References (8)

1. G. Puckrein, "BiDil: From Another Vantage Point," Health Affairs 25 (2006): w368-w374 (published online 15 August 2006; 10.1377/hlthaff25.w368).
2. P. Sankar and J. Kahn, "BiDil: Race Medicine or Race Marketing?" Health Affairs 24 (2005): w455-w463 (published online 11 October 2005; 10.1377/hlthaff.w5.455).
3. S.A. Hunt et al., "ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult," Circulation 112, no. 12 (2005): e154-e235 (available online at http://circ.ahajournals.org/cgi/ content/full/112/12/e154; accessed 1 June 2006).
4. D. Gellene, "Heart Pill Intended Only for Blacks Sparks Debate," Los Angeles Times, 16 June 2005.
5. D. Gellene, "Heart Pill Intended Only for Blacks Sparks Debate," Los Angeles Times, 2005.Ibid.
6. To obtain this information, we visited the Centers for Disease Control and Prevention's (CDC's) Wonder Web site, http://wonder.cdc.gov. The percentages were derived from queries for information concerning compressed mortality by race, adjusted for ages 45-64 and age 65 and above. In the over-age-sixty-five group, the crude death rate for blacks is 142.9 per 100,000; for whites it is 153.3 per 100,000 (accessed 11 January 2005).
7. See J.G. Douglas et al., "Management of High Blood Pressure in African Americans," Archives of Internal Medicine 163, no. 5 (2003): 525-541 (available online at http://ishib.org/supportfiles/ Mgt_of_Hypertension_in_African_Americans.pdf; accessed 13 June 2006);
8. and A.L. Taylor et al., "Combination of Isosorbide Dinitrate and Hydralazine in Blacks with Heart Failure," New England Journal of Medicine 351, no. 20 (2004): 2049-2057.