Stereoselective pharmacokinetics of cetirizine in the guinea pig: Role of protein binding

Biopharmaceutics and Drug Disposition

Volumn 27, Issue 6, 2006, Pages 291-297

  Gupta, Anubha ^a   Hammarlund Udenaes, Margareta ^a   Chatelain, Pierre ^b   Massingham, Roy ^b   Jonsson, E Niclas ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b UCB PHARMA   (Belgium)

Author keywords

Antihistamines; Pharmacokinetic; Protein binding; Stereoselective

Indexed keywords

ANTIHISTAMINIC AGENT; CETIRIZINE; DEXTROCETIRIZINE; LEVOCETIRIZINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; BLOOD SAMPLING; COMPARTMENT MODEL; COMPUTER PROGRAM; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG INFUSION; DRUG PROTEIN BINDING; ENANTIOMER; EQUILIBRIUM DIALYSIS; GUINEA PIG; HUMAN; IN VITRO STUDY; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; NONHUMAN; RACEMIC MIXTURE; STEADY STATE; STEREOCHEMISTRY;

ANIMALS; ANTI-ALLERGIC AGENTS; CETIRIZINE; DIALYSIS; GUINEA PIGS; HUMANS; MODELS, STATISTICAL; PROTEIN BINDING; STEREOISOMERISM;

EID: 33749351417     PISSN: 01422782     EISSN: 1099081X     Source Type: Journal    
DOI: 10.1002/bdd.509     Document Type: Article

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