Model-based design of growth-attenuated viruses

PLoS Computational Biology

Volumn 2, Issue 9, 2006, Pages 1001-1016

  Lim, Kwang Il ^a,b   Lang, Tobias ^a,c   Lam, Vy ^a,d   Yin, John ^a  

^a University of Wisconsin Madison   (United States)

^b University of California   (United States)

^c UNIVERSITY OF STUTTGART   (Germany)

^d VIRGINIA BIOINFORMATICS INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RNA; TRANSCRIPTION; VIRUSES;

CANNOT LINKS; GENETIC MODIFICATIONS; LIVE VIRUS; MODEL-BASED DESIGN; PATHOGENIC EFFECTS; PATHOGENIC MECHANISMS; SUBUNIT VACCINE; VESICULAR STOMATITIS VIRUS; VIRAL GENOME; WILD TYPES;

VACCINES;

GLYCOPROTEIN; LIVE VACCINE; MESSENGER RNA; VIRUS PROTEIN; VIRUS VACCINE;

ANIMAL CELL; ARTICLE; COMPUTER MODEL; COMPUTER SIMULATION; CONTROLLED STUDY; GENE EXPRESSION; GENE LOCATION; GENE OVEREXPRESSION; GENE REARRANGEMENT; GENETIC TRANSCRIPTION; GENOTYPE PHENOTYPE CORRELATION; NONHUMAN; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RNA TRANSLATION; VESICULAR STOMATITIS VIRUS; VIROGENESIS; VIRUS ADSORPTION; VIRUS ASSEMBLY; VIRUS ATTENUATION; VIRUS GENOME; VIRUS INFECTION; VIRUS NUCLEOCAPSID; VIRUS REPLICATION; ANIMAL; BIOLOGICAL MODEL; BIOLOGY; BIOSYNTHESIS; CELL LINE; GENETICS; HAMSTER; METABOLISM; MOUSE; PHYSIOLOGY; PROMOTER REGION; PROTEIN SYNTHESIS;

RNA VIRUSES; VESICULAR STOMATITIS VIRUS;

ANIMALS; CELL LINE; COMPUTATIONAL BIOLOGY; CRICETINAE; GENOME, VIRAL; MICE; MODELS, BIOLOGICAL; NUCLEOCAPSID; PROMOTER REGIONS, GENETIC; PROTEIN BIOSYNTHESIS; RNA, MESSENGER; VACCINES, ATTENUATED; VESICULAR STOMATITIS INDIANA VIRUS; VIRAL PROTEINS; VIRAL VACCINES; VIRUS REPLICATION;

EID: 33749350509     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi/0020116     Document Type: Article

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