메뉴 건너뛰기




Volumn 108, Issue 7, 2006, Pages 2216-2222

Thrombotic complications in childhood acute lymphoblastic leukemia: A meta-analysis of 17 prospective studies comprising 1752 pediatric patients

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRACYCLINE; ANTITHROMBIN III; ASPARAGINASE; PREDNISONE;

EID: 33749332107     PISSN: 00064971     EISSN: 00064971     Source Type: Journal    
DOI: 10.1182/blood-2006-04-015511     Document Type: Article
Times cited : (325)

References (114)
  • 1
    • 14644438502 scopus 로고    scopus 로고
    • A systematic literature review of the clinical and epidemiological burden of acute lymphoblastic leukaemia (ALL)
    • Redaelli A, Laskin BL, Stephens JM, Botteman MF, Pashos CL. A systematic literature review of the clinical and epidemiological burden of acute lymphoblastic leukaemia (ALL). Europ J Cancer Care. 2005;14:53-62.
    • (2005) Europ J Cancer Care , vol.14 , pp. 53-62
    • Redaelli, A.1    Laskin, B.L.2    Stephens, J.M.3    Botteman, M.F.4    Pashos, C.L.5
  • 2
    • 0346849903 scopus 로고    scopus 로고
    • Thrombosis in children with acute lymphoblastic leukaemia: Epidemiology of thrombosis in children with acute lymphoblastic leukaemia
    • Athale UH, Chan AKC. Thrombosis in children with acute lymphoblastic leukaemia: epidemiology of thrombosis in children with acute lymphoblastic leukaemia. Thrombosis Res. 2003;111:125-131.
    • (2003) Thrombosis Res , vol.111 , pp. 125-131
    • Athale, U.H.1    Chan, A.K.C.2
  • 3
    • 0345802675 scopus 로고    scopus 로고
    • Thrombosis in children with acute lymphoblastic leukaemia: Pathogenesis of thrombosis in children with acute lymphoblastic leukaemia: effect of the disease and therapy
    • Athale UH, Chan AKC. Thrombosis in children with acute lymphoblastic leukaemia: pathogenesis of thrombosis in children with acute lymphoblastic leukaemia: effect of the disease and therapy. Thrombosis Res. 2003;111:199-212.
    • (2003) Thrombosis Res , vol.111 , pp. 199-212
    • Athale, U.H.1    Chan, A.K.C.2
  • 4
    • 0346787804 scopus 로고    scopus 로고
    • Thrombosis in children with acute lymphoblastic leukaemia: Pathogenesis of thrombosis in children with acute lymphoblastic leukaemia: effect of host environment
    • Athale UH, Chan AKC. Thrombosis in children with acute lymphoblastic leukaemia: pathogenesis of thrombosis in children with acute lymphoblastic leukaemia: effect of host environment. Thrombosis Res. 2003;111:321-327.
    • (2003) Thrombosis Res , vol.111 , pp. 321-327
    • Athale, U.H.1    Chan, A.K.C.2
  • 5
    • 0042351192 scopus 로고    scopus 로고
    • The complex nature of the prothrombotic state in acute lymphoblastic leukemia of childhood
    • Jaime-Perez JC, Gomez-Almaguer D. The complex nature of the prothrombotic state in acute lymphoblastic leukemia of childhood. Haematologica. 2003;88:ELT25.
    • (2003) Haematologica , vol.88
    • Jaime-Perez, J.C.1    Gomez-Almaguer, D.2
  • 6
    • 0033051113 scopus 로고    scopus 로고
    • Thrombosis related to the use of L-Asparaginase in adults with acute lymphoblastic leukemia: A need to consider coagulation monitoring and clotting factor replacement
    • Alberts SR, Bretscher M, Wiltsie JC, O'Neill BP, Mokri B, Witzig TE. Thrombosis related to the use of L-Asparaginase in adults with acute lymphoblastic leukemia: a need to consider coagulation monitoring and clotting factor replacement. Leuk Lymphoma. 1999;32:489-496.
    • (1999) Leuk Lymphoma , vol.32 , pp. 489-496
    • Alberts, S.R.1    Bretscher, M.2    Wiltsie, J.C.3    O'Neill, B.P.4    Mokri, B.5    Witzig, T.E.6
  • 7
    • 0035035486 scopus 로고    scopus 로고
    • Cryoprecipitate-induced mesenteric venous thrombosis during L-Asparaginase therapy for acute lymphoblastic leukemia
    • Musa MO, Al-Fair F, Al-Mohareb F, Al-Saeed H, Aljurf M. Cryoprecipitate-induced mesenteric venous thrombosis during L-Asparaginase therapy for acute lymphoblastic leukemia. Leuk Lymphoma. 2001;40:429-431.
    • (2001) Leuk Lymphoma , vol.40 , pp. 429-431
    • Musa, M.O.1    Al-Fair, F.2    Al-Mohareb, F.3    Al-Saeed, H.4    Aljurf, M.5
  • 8
    • 0022444252 scopus 로고
    • Lack of pathogenetic role of protein C and S in thrombosis associated with asparaginase-prednisone-vincristine therapy for leukemia
    • Pui CH, Chesney CM, Bergum PW, Jackson CW, Rapaport SI. Lack of pathogenetic role of protein C and S in thrombosis associated with asparaginase-prednisone-vincristine therapy for leukemia. Br J Haematol. 1986;64:283-290.
    • (1986) Br J Haematol , vol.64 , pp. 283-290
    • Pui, C.H.1    Chesney, C.M.2    Bergum, P.W.3    Jackson, C.W.4    Rapaport, S.I.5
  • 9
    • 0019131326 scopus 로고
    • Dural venous sinus thrombosis in acute lymphoblastic leukemia
    • Lockman LA, Mastri A, Priest JR, Nesbit M. Dural venous sinus thrombosis in acute lymphoblastic leukemia. Pediatrics. 1980;66:943-947.
    • (1980) Pediatrics , vol.66 , pp. 943-947
    • Lockman, L.A.1    Mastri, A.2    Priest, J.R.3    Nesbit, M.4
  • 10
    • 0038616075 scopus 로고    scopus 로고
    • Cerebrovascular complications of L-Asparaginase in the therapy of acute lymphoblastic leukemia
    • Kieslich M, Porto L, Lanfermann H, Jacobi G, Schwabe D, Bohles H. Cerebrovascular complications of L-Asparaginase in the therapy of acute lymphoblastic leukemia. J Ped Hematol Oncol. 2003;25:484-487.
    • (2003) J Ped Hematol Oncol , vol.25 , pp. 484-487
    • Kieslich, M.1    Porto, L.2    Lanfermann, H.3    Jacobi, G.4    Schwabe, D.5    Bohles, H.6
  • 11
    • 0023187934 scopus 로고
    • Involvement of von Willebrand factor in thrombosis following asparaginase-prednisone-vincristine therapy for leukemia
    • Pui CH, Jackson CW, Chesney CM, Abildgaard CF. Involvement of von Willebrand factor in thrombosis following asparaginase-prednisone-vincristine therapy for leukemia. Am J Hematol. 1987;25:291-298.
    • (1987) Am J Hematol , vol.25 , pp. 291-298
    • Pui, C.H.1    Jackson, C.W.2    Chesney, C.M.3    Abildgaard, C.F.4
  • 12
    • 0021931786 scopus 로고
    • Thromboembolic complicatins associated with L-Asparaginase therapy
    • Kucuk O, Kwaan HC, Gunnar W, Vazquez RM. Thromboembolic complicatins associated with L-Asparaginase therapy. Cancer. 1985;55:702-706.
    • (1985) Cancer , vol.55 , pp. 702-706
    • Kucuk, O.1    Kwaan, H.C.2    Gunnar, W.3    Vazquez, R.M.4
  • 13
    • 0023800081 scopus 로고
    • Sequelae of thrombotic or hemorrhagic complications following L-Asparaginase therapy for childhood lymphoblastic leukemia
    • Ott N, Ramsay NK, Priest JR, et al. Sequelae of thrombotic or hemorrhagic complications following L-Asparaginase therapy for childhood lymphoblastic leukemia. Am J Ped Hematol Oncol. 1988;10:191-195.
    • (1988) Am J Ped Hematol Oncol , vol.10 , pp. 191-195
    • Ott, N.1    Ramsay, N.K.2    Priest, J.R.3
  • 14
    • 17044452961 scopus 로고
    • Thrombotic complications during L-Asparaginase related to protein C deficiency
    • [letter]
    • Velenga E, Broekmans AW, Kluft C. Thrombotic complications during L-Asparaginase related to protein C deficiency [letter]. Thromb Haemostas. 1985;53:443.
    • (1985) Thromb Haemostas , vol.53 , pp. 443
    • Velenga, E.1    Broekmans, A.W.2    Kluft, C.3
  • 15
    • 0018958359 scopus 로고
    • Thrombotic and hemorrhagic strokes complicating early therapy for childhood acute lymphoblastic leukemia
    • Priest JR, Ramsay NK, Latchaw RE et al. Thrombotic and hemorrhagic strokes complicating early therapy for childhood acute lymphoblastic leukemia. Cancer. 1980;46:1548-1554.
    • (1980) Cancer , vol.46 , pp. 1548-1554
    • Priest, J.R.1    Ramsay, N.K.2    Latchaw, R.E.3
  • 16
    • 0018989932 scopus 로고
    • AT III deficiency during L-asp therapy
    • Pitney WR, Phadke KP, Dean S. AT III deficiency during L-asp therapy. Lancet. 1980;1:493-494.
    • (1980) Lancet , vol.1 , pp. 493-494
    • Pitney, W.R.1    Phadke, K.P.2    Dean, S.3
  • 18
    • 0033462128 scopus 로고    scopus 로고
    • Assessment of coagulation disorders in patients with acute leukemia before and after cytostatic treatment
    • Chojnowski K, Wawrzyniak E, Trelinski J, Niewiarowska J, Cierniewski C. Assessment of coagulation disorders in patients with acute leukemia before and after cytostatic treatment. Leuk Lymphoma. 1999;36:77-84.
    • (1999) Leuk Lymphoma , vol.36 , pp. 77-84
    • Chojnowski, K.1    Wawrzyniak, E.2    Trelinski, J.3    Niewiarowska, J.4    Cierniewski, C.5
  • 19
    • 0034017471 scopus 로고    scopus 로고
    • Children with acute lymphoblastic leukemia: Is there any subgroup of children without elevated thrombin generation? A preliminary study utilizing measurements of thrombin-antithrombin III complexes
    • Uszynski M, Osinska M, Zekanowska E, Ziolkowska E. Children with acute lymphoblastic leukemia: is there any subgroup of children without elevated thrombin generation? a preliminary study utilizing measurements of thrombin-antithrombin III complexes. Med Sci Monit. 2000;6:108-111.
    • (2000) Med Sci Monit , vol.6 , pp. 108-111
    • Uszynski, M.1    Osinska, M.2    Zekanowska, E.3    Ziolkowska, E.4
  • 20
    • 0020678228 scopus 로고
    • L-asparaginase induced antithrombin III deficiency: Evidence against the production of a hypercoagulable state
    • Bauer KA, Teitel JM, Rosenberg RD. L-asparaginase induced antithrombin III deficiency: evidence against the production of a hypercoagulable state. Thromb Res. 1983;29:437-442.
    • (1983) Thromb Res , vol.29 , pp. 437-442
    • Bauer, K.A.1    Teitel, J.M.2    Rosenberg, R.D.3
  • 21
    • 0024326179 scopus 로고
    • Changes in hemostatic and fibrinolytic proteins in patients receiving L-asparaginase therapy
    • Saito M, Asakura H, Jokaji H, et al. Changes in hemostatic and fibrinolytic proteins in patients receiving L-asparaginase therapy. Am J Hematol. 1989;32:20-23.
    • (1989) Am J Hematol , vol.32 , pp. 20-23
    • Saito, M.1    Asakura, H.2    Jokaji, H.3
  • 22
    • 0027190609 scopus 로고
    • Hypercoagulability during induction therapy of acute lymphoblastic leukemia is of scarce clinical relevance: Gruppo Italiano Malattie Ematologiche Maligne dell' Adulto
    • de Stefano V, Gugliotta L, Mazzucconi MG, Leone G, Mandelli F. Hypercoagulability during induction therapy of acute lymphoblastic leukemia is of scarce clinical relevance: Gruppo Italiano Malattie Ematologiche Maligne dell' Adulto. Blood. 1993;81:2468-2469.
    • (1993) Blood , vol.81 , pp. 2468-2469
    • De Stefano, V.1    Gugliotta, L.2    Mazzucconi, M.G.3    Leone, G.4    Mandelli, F.5
  • 23
    • 13344287038 scopus 로고    scopus 로고
    • Disseminated intravascular coagulation in adult acute lymphoblastic leukemia: Frequent complications with fibrinogen levels less than 100 mg/dl
    • Sarris A, Cortes J, Kantarjian H, et al. Disseminated intravascular coagulation in adult acute lymphoblastic leukemia: frequent complications with fibrinogen levels less than 100 mg/dl. Leuk Lymphoma. 1996;21:85-92.
    • (1996) Leuk Lymphoma , vol.21 , pp. 85-92
    • Sarris, A.1    Cortes, J.2    Kantarjian, H.3
  • 24
    • 0026782856 scopus 로고
    • Acute lymphoblastic leukemia: Hypofibrinogenemia with a low incidence of clinical complications is often found during induction remission therapy
    • Solano C, Lopez J, Gomez N, Fernandez-Ranada JM. Acute lymphoblastic leukemia: hypofibrinogenemia with a low incidence of clinical complications is often found during induction remission therapy. Blood. 1992;80:1366-1368.
    • (1992) Blood , vol.80 , pp. 1366-1368
    • Solano, C.1    Lopez, J.2    Gomez, N.3    Fernandez-Ranada, J.M.4
  • 25
    • 0017763722 scopus 로고
    • The effect of L-asparaginase of plasma coagulation factors in acute lymphoblastic leukemia
    • Ramsay NK, Coccia PF, Krivit W, Nesbit ME, Edson JR. The effect of L-asparaginase of plasma coagulation factors in acute lymphoblastic leukemia. Cancer. 1977;40:1398-1401.
    • (1977) Cancer , vol.40 , pp. 1398-1401
    • Ramsay, N.K.1    Coccia, P.F.2    Krivit, W.3    Nesbit, M.E.4    Edson, J.R.5
  • 26
    • 0028877101 scopus 로고
    • Inefficacy of fresh frozen plasma in the treatment of L-Asparaginase-induced coagulation factor deficiencies during all induction therapy
    • Nowak-Gottl U, Rath B, Binder M, et al. Inefficacy of fresh frozen plasma in the treatment of L-Asparaginase-induced coagulation factor deficiencies during all induction therapy. Haematologica. 1995;80:451-453.
    • (1995) Haematologica , vol.80 , pp. 451-453
    • Nowak-Gottl, U.1    Rath, B.2    Binder, M.3
  • 27
    • 0026356652 scopus 로고
    • Clotting abnormalities in children during maintenance chemotherapy for acute lymphoblastic leukemia
    • Arico M, Gamba G, Raiteri E, Montani N, De Amici M, Burgio R. Clotting abnormalities in children during maintenance chemotherapy for acute lymphoblastic leukemia. Haematologica. 1991;76:472-474.
    • (1991) Haematologica , vol.76 , pp. 472-474
    • Arico, M.1    Gamba, G.2    Raiteri, E.3    Montani, N.4    De Amici, M.5    Burgio, R.6
  • 28
    • 0021253795 scopus 로고
    • Intensified therapy in acute lymphoblastic and acute undifferentiated leukaemia in adults
    • Hoelzer D, Thiel E, Loffler H, et al. Intensified therapy in acute lymphoblastic and acute undifferentiated leukaemia in adults. Blood. 1984;64:38-47.
    • (1984) Blood , vol.64 , pp. 38-47
    • Hoelzer, D.1    Thiel, E.2    Loffler, H.3
  • 29
    • 0027984405 scopus 로고
    • Fresh frozen plasma has no beneficial effect on the hemostatic system in children receiving L-Asparaginase
    • Halton JM, Mitchell LG, Vegh P, Eves M, Andrew ME. Fresh frozen plasma has no beneficial effect on the hemostatic system in children receiving L-Asparaginase. Am J Hematol. 1994;47:157-161.
    • (1994) Am J Hematol , vol.47 , pp. 157-161
    • Halton, J.M.1    Mitchell, L.G.2    Vegh, P.3    Eves, M.4    Andrew, M.E.5
  • 30
    • 0026628059 scopus 로고
    • Treatment of adult acute lymphoblastic leukaemia over a 16 year period
    • Bassan R, Battista R, Rohatiner AZS, et al. Treatment of adult acute lymphoblastic leukaemia over a 16 year period. Leukemia. 1992,6:186-190.
    • (1992) Leukemia , vol.6 , pp. 186-190
    • Bassan, R.1    Battista, R.2    Rohatiner, A.Z.S.3
  • 31
    • 0344849429 scopus 로고    scopus 로고
    • Changes of hemostatic factors in children with acute lymphoblastic leukaemia receiving combined chemotherapy including high dose methylprednisolone and L-Asparaginase
    • Oner AF, Gurgey A, Kirazli S, Okur H, Tunc B. Changes of hemostatic factors in children with acute lymphoblastic leukaemia receiving combined chemotherapy including high dose methylprednisolone and L-Asparaginase. Leuk Lymphoma. 1999;33:361-364.
    • (1999) Leuk Lymphoma , vol.33 , pp. 361-364
    • Oner, A.F.1    Gurgey, A.2    Kirazli, S.3    Okur, H.4    Tunc, B.5
  • 32
    • 0025743639 scopus 로고
    • A regimen for antithrombin III substitution in patients with acute lymphoblastic leucemia under treatment with L-asparaginase
    • Belmonte MM, Guliotta L, Delvos U, et al. A regimen for antithrombin III substitution in patients with acute lymphoblastic leucemia under treatment with L-asparaginase. Haematologica. 1991;76:209-214.
    • (1991) Haematologica , vol.76 , pp. 209-214
    • Belmonte, M.M.1    Guliotta, L.2    Delvos, U.3
  • 33
    • 0021032126 scopus 로고
    • Influence of intensive asparaginase in the treatment of childhood non-T-cell acute lymphoblastic leukaemia
    • Sallan SE, Hitchcock-Bryan S, Gelber R, Robert Cassady J, Frei E III, Nathan DG. Influence of intensive asparaginase in the treatment of childhood non-T-cell acute lymphoblastic leukaemia. Cancer Res. 1983;43:5601-5607.
    • (1983) Cancer Res , vol.43 , pp. 5601-5607
    • Sallan, S.E.1    Hitchcock-Bryan, S.2    Gelber, R.3    Robert Cassady, J.4    Frei III, E.5    Nathan, D.G.6
  • 34
    • 0025642988 scopus 로고
    • Non-randomised study comparing toxicity of Escherichia coli and Erwinia asparaginase in children with leukaemia
    • Eden OB, Shaw MP, Lilleyman JS, Richards S. Non-randomised study comparing toxicity of Escherichia coli and Erwinia asparaginase in children with leukaemia. Med Pediatr Oncol. 1990;18:497-502.
    • (1990) Med Pediatr Oncol , vol.18 , pp. 497-502
    • Eden, O.B.1    Shaw, M.P.2    Lilleyman, J.S.3    Richards, S.4
  • 35
    • 0022620372 scopus 로고
    • Improved disease-free survival of children with acute lymphoblastic leukaemia at high risk for early relapse with the New York regimen: A new intensive therapy protocol: A report from the Children's Cancer Study Group
    • Steinherz PG, Gaynon P, Miller DR, et al. Improved disease-free survival of children with acute lymphoblastic leukaemia at high risk for early relapse with the New York regimen: a new intensive therapy protocol: a report from the Children's Cancer Study Group. J Clin Oncol. 1986;4:744-752.
    • (1986) J Clin Oncol , vol.4 , pp. 744-752
    • Steinherz, P.G.1    Gaynon, P.2    Miller, D.R.3
  • 36
    • 0021014939 scopus 로고
    • Sequential changes in platelet function and coagulation in leukemic children treated with L-Asparaginase, prednisone and vincristine
    • Pui CH, Jackson CW, Chesney C, et al. Sequential changes in platelet function and coagulation in leukemic children treated with L-Asparaginase, prednisone and vincristine. J Clin Oncol. 1983;1:380-385.
    • (1983) J Clin Oncol , vol.1 , pp. 380-385
    • Pui, C.H.1    Jackson, C.W.2    Chesney, C.3
  • 37
    • 0017796689 scopus 로고
    • Combination chemotherapy for acute lymphoblastic leukaemia in adults
    • Lister TA, Whitehouse JM, Beard ME, et al. Combination chemotherapy for acute lymphoblastic leukaemia in adults. Br Med J. 1978;1:199-203.
    • (1978) Br Med J , vol.1 , pp. 199-203
    • Lister, T.A.1    Whitehouse, J.M.2    Beard, M.E.3
  • 38
    • 0028079405 scopus 로고
    • Acquired antithrombin III deficiency secondary to asparaginase therapy in childhood acute lymphoblastic leukaemia
    • Andrew M, Brooker L, Mitchell L. Acquired antithrombin III deficiency secondary to asparaginase therapy in childhood acute lymphoblastic leukaemia. Blood Coag Fibrinolysis. 1994;5:S24-S36.
    • (1994) Blood Coag Fibrinolysis , vol.5
    • Andrew, M.1    Brooker, L.2    Mitchell, L.3
  • 40
    • 0035216041 scopus 로고    scopus 로고
    • Disseminated intravascular coagulation in acute leukaemia
    • Barbui T, Falanga A. Disseminated intravascular coagulation in acute leukaemia. Seminars Thromb Hemost. 2001;27:593-604.
    • (2001) Seminars Thromb Hemost , vol.27 , pp. 593-604
    • Barbui, T.1    Falanga, A.2
  • 41
    • 0034994309 scopus 로고    scopus 로고
    • Thrombotic risk in children with acute lymphoblastic leukaemia
    • Dreyfus M. Thrombotic risk in children with acute lymphoblastic leukaemia. Ped Hematol Oncol. 2001;18:233-234.
    • (2001) Ped Hematol Oncol , vol.18 , pp. 233-234
    • Dreyfus, M.1
  • 42
    • 0344196932 scopus 로고    scopus 로고
    • Prospective evaluation of the thrombotic risk in children with acute lymphoblastic leukemia carrying the MTHFR TT 677 genotype, the prothrombin G20210A variant, and further prothrombotic risk factors
    • Nowak-Gottl U, Wermes C, Junker R, et al. Prospective evaluation of the thrombotic risk in children with acute lymphoblastic leukemia carrying the MTHFR TT 677 genotype, the prothrombin G20210A variant, and further prothrombotic risk factors. Blood. 1999;93:1595-1599.
    • (1999) Blood , vol.93 , pp. 1595-1599
    • Nowak-Gottl, U.1    Wermes, C.2    Junker, R.3
  • 43
    • 0343431525 scopus 로고    scopus 로고
    • Prothrombotic risk factors in children with acute lymphoblastic leukemia treated with delayed E. coli asparaginase (COALL-92 and 97 protocols)
    • Mauz-Korholz C, Junker R, Gobel U, Nowak-Gottl U. Prothrombotic risk factors in children with acute lymphoblastic leukemia treated with delayed E. coli asparaginase (COALL-92 and 97 protocols). Thromb Haemost. 2000;83:840-843.
    • (2000) Thromb Haemost , vol.83 , pp. 840-843
    • Mauz-Korholz, C.1    Junker, R.2    Gobel, U.3    Nowak-Gottl, U.4
  • 44
    • 12444304442 scopus 로고    scopus 로고
    • Trend to efficacy and safety using antithrombin concentrate in prevention of thrombosis in children receiving L-asparaginase for acute lymphoblastic leukemia: Results of the PAARKA study
    • Mitchell L, Andrew M, Hanna K, et al. Trend to efficacy and safety using antithrombin concentrate in prevention of thrombosis in children receiving L-asparaginase for acute lymphoblastic leukemia: results of the PAARKA study. Thromb Haemost. 2003;90:235-244.
    • (2003) Thromb Haemost , vol.90 , pp. 235-244
    • Mitchell, L.1    Andrew, M.2    Hanna, K.3
  • 45
    • 0036213044 scopus 로고    scopus 로고
    • Comparison of venography and ultrasound for the diagnosis of asymptomatic deep vein thrombosis in the upper body in children: Results of the PARKAA study: Prophylactic Antithrombin Replacement in Kids with ALL treated with Asparaginase
    • Male C, Chait P, Ginsberg JS, et al. Comparison of venography and ultrasound for the diagnosis of asymptomatic deep vein thrombosis in the upper body in children: results of the PARKAA study: Prophylactic Antithrombin Replacement in Kids with ALL treated with Asparaginase. Thromb Haemost. 2002;87:593-598.
    • (2002) Thromb Haemost , vol.87 , pp. 593-598
    • Male, C.1    Chait, P.2    Ginsberg, J.S.3
  • 46
    • 0035283163 scopus 로고    scopus 로고
    • Improved outcome for children with acute lymphoblastic leukemia: Results of Dana-Farber Consortium Protocol 91-01
    • Silverman LB, Gelber RD, Dalton VK, et al. Improved outcome for children with acute lymphoblastic leukemia: results of Dana-Farber Consortium Protocol 91-01. Blood. 2001;97:1211-1217.
    • (2001) Blood , vol.97 , pp. 1211-1217
    • Silverman, L.B.1    Gelber, R.D.2    Dalton, V.K.3
  • 47
    • 0037089437 scopus 로고    scopus 로고
    • Comparison of Escherichia coli-asparaginase with Erwinia-asparaginase in the treatment of childhood lymphoid malignancies: Results of a randomized European Organization for Research and Treatment of Cancer-Children's Leukemia Group phase 3 trial
    • Duval M, Suciu S, Ferster A, et al. Comparison of Escherichia coli-asparaginase with Erwinia-asparaginase in the treatment of childhood lymphoid malignancies: results of a randomized European Organization for Research and Treatment of Cancer-Children's Leukemia Group phase 3 trial. Blood. 2002;99:2734-2739.
    • (2002) Blood , vol.99 , pp. 2734-2739
    • Duval, M.1    Suciu, S.2    Ferster, A.3
  • 49
    • 0026548513 scopus 로고
    • High incidence of disseminated intravascular coagulation during remission induction of adult patients with acute lymphoblastic leukemia
    • Sarris AH, Kempin S, Berman E, et al. High incidence of disseminated intravascular coagulation during remission induction of adult patients with acute lymphoblastic leukemia. Blood. 1992;79:1305-1310.
    • (1992) Blood , vol.79 , pp. 1305-1310
    • Sarris, A.H.1    Kempin, S.2    Berman, E.3
  • 50
    • 0026702771 scopus 로고
    • Incidence of thrombotic complications in adult patients with acute lymphoblastic leukaemia receiving L-asparaginase during induction therapy: A retrospective study: The GIMEMA Group
    • Gugliotta L, Mazzucconi MG, Leone G, et al. Incidence of thrombotic complications in adult patients with acute lymphoblastic leukaemia receiving L-asparaginase during induction therapy: a retrospective study: The GIMEMA Group. Eur J Haematol. 1992;49:63-66.
    • (1992) Eur J Haematol , vol.49 , pp. 63-66
    • Gugliotta, L.1    Mazzucconi, M.G.2    Leone, G.3
  • 52
    • 9644307948 scopus 로고    scopus 로고
    • Symptomatic venous thromboembolism in acute leukemia: Incidence, risk factors, and impact on prognosis
    • Ziegler S, Sperr WR, Knobl P, et al. Symptomatic venous thromboembolism in acute leukemia: incidence, risk factors, and impact on prognosis. Thromb Res. 2005;115:59-64.
    • (2005) Thromb Res , vol.115 , pp. 59-64
    • Ziegler, S.1    Sperr, W.R.2    Knobl, P.3
  • 53
    • 9644265540 scopus 로고    scopus 로고
    • Thrombosis associated with L-asparaginase therapy and low fibrinogen levels in adult acute lymphoblastic leukemia
    • Beinart G, Damon L. Thrombosis associated with L-asparaginase therapy and low fibrinogen levels in adult acute lymphoblastic leukemia. Am J Hematol. 2004;77:331-335.
    • (2004) Am J Hematol , vol.77 , pp. 331-335
    • Beinart, G.1    Damon, L.2
  • 54
    • 3042777511 scopus 로고    scopus 로고
    • Thromboembolism in adults with acute lymphoblastic leukemia during induction with L-asparaginase-containing multi-agent regimens: Incidence, risk factors, and possible role of antithrombin
    • Elliott MA, Wolf RC, Hook CC, et al. Thromboembolism in adults with acute lymphoblastic leukemia during induction with L-asparaginase-containing multi-agent regimens: incidence, risk factors, and possible role of antithrombin. Leuk Lymphoma. 2004;45:1545-1549.
    • (2004) Leuk Lymphoma , vol.45 , pp. 1545-1549
    • Elliott, M.A.1    Wolf, R.C.2    Hook, C.C.3
  • 55
    • 0025348062 scopus 로고
    • Tura S Hypercoagulability during L-asparaginase treatment: The effect of antithrombin III supplementation in vivo
    • Gugliotta L, D'Angelo A, Mattioli Belmonte M, et al. Tura S Hypercoagulability during L-asparaginase treatment: the effect of antithrombin III supplementation in vivo. Br J Haematol. 1990;74:465-470.
    • (1990) Br J Haematol , vol.74 , pp. 465-470
    • Gugliotta, L.1    D'Angelo, A.2    Mattioli Belmonte, M.3
  • 56
    • 0025130158 scopus 로고
    • L-asparaginase treatment reduces the anticoagulant potential of the protein C system without affecting vitamin K-dependent carboxylation
    • Vigano'D'Angelo S, Gugliotta L, Mattioli Belmonte M, Cascione ML, Pattarini E, D'Angelo A. L-asparaginase treatment reduces the anticoagulant potential of the protein C system without affecting vitamin K-dependent carboxylation. Thromb Res. 1990;59:985-994.
    • (1990) Thromb Res , vol.59 , pp. 985-994
    • Vigano'D'angelo, S.1    Gugliotta, L.2    Mattioli Belmonte, M.3    Cascione, M.L.4    Pattarini, E.5    D'Angelo, A.6
  • 57
    • 0025176891 scopus 로고
    • Fibrinopeptide a changes during remission induction treatment with L-asparaginase in acute lymphoblastic leukemia: Evidence for activation of blood coagulation
    • Rodeghiero F, Castaman G, Dini E. Fibrinopeptide A changes during remission induction treatment with L-asparaginase in acute lymphoblastic leukemia: evidence for activation of blood coagulation. Thromb Res. 1990;57:31-38.
    • (1990) Thromb Res , vol.57 , pp. 31-38
    • Rodeghiero, F.1    Castaman, G.2    Dini, E.3
  • 58
    • 0028218161 scopus 로고
    • Antithrombin III infusion suppresses the hypercoagulable state in adult acute lymphoblastic leukaemia patients treated with a low dose of Escherichia coli L-asparaginase: A GIMEMA study
    • Mazzucconi MG, Gugliotta L, Leone G, et al. Antithrombin III infusion suppresses the hypercoagulable state in adult acute lymphoblastic leukaemia patients treated with a low dose of Escherichia coli L-asparaginase: a GIMEMA study. Blood Coagul Fibrinolysis. 1994;5:23-28.
    • (1994) Blood Coagul Fibrinolysis , vol.5 , pp. 23-28
    • Mazzucconi, M.G.1    Gugliotta, L.2    Leone, G.3
  • 60
    • 0028589586 scopus 로고
    • Negligible hemostatic toxicty of intermediate-dose erwinase in adult patients with acute lymphoblastic leucemia: Preliminary data
    • Nocentini F, Gugliotta L, Catani L, et al. Negligible hemostatic toxicty of intermediate-dose erwinase in adult patients with acute lymphoblastic leucemia: preliminary data. Haematologica. 1994;79:546-549.
    • (1994) Haematologica , vol.79 , pp. 546-549
    • Nocentini, F.1    Gugliotta, L.2    Catani, L.3
  • 61
    • 0019958843 scopus 로고
    • Depression of functional and antigenic plasma antithrombin III (AT-III) due to therapy with L-asparaginase
    • Liebman HA, Wada JK, Patch MJ, McGehee W. Depression of functional and antigenic plasma antithrombin III (AT-III) due to therapy with L-asparaginase. Cancer. 1982;50:451-456.
    • (1982) Cancer , vol.50 , pp. 451-456
    • Liebman, H.A.1    Wada, J.K.2    Patch, M.J.3    McGehee, W.4
  • 63
    • 0025639167 scopus 로고
    • Thrombotic complications during L-asparaginase treatment for acute lymphocytic leukemia
    • Castaman G, Rodeghiero F, Dini E. Thrombotic complications during L-asparaginase treatment for acute lymphocytic leukemia. Haematologica. 1990;75:567-569.
    • (1990) Haematologica , vol.75 , pp. 567-569
    • Castaman, G.1    Rodeghiero, F.2    Dini, E.3
  • 64
    • 0027469269 scopus 로고
    • Evidence of a hypercoagulable state in patients with acute lymphoblastic leukemia treated with low dose of E. coli L-asparaginase: A GIMEMA study
    • Leone G, Gugliotta L, Mazzucconi MG, et al. Evidence of a hypercoagulable state in patients with acute lymphoblastic leukemia treated with low dose of E. coli L-asparaginase: a GIMEMA study. Thromb Haemost. 1993;69:12-15.
    • (1993) Thromb Haemost , vol.69 , pp. 12-15
    • Leone, G.1    Gugliotta, L.2    Mazzucconi, M.G.3
  • 65
    • 0020693506 scopus 로고
    • Fatal pulmonary embolism and antithrombin III deficiency in adult lymphoblastic leukaemia during L-asparaginase therapy
    • Barbui T, Rodeghiero F, Meli S, Dini E. Fatal pulmonary embolism and antithrombin III deficiency in adult lymphoblastic leukaemia during L-asparaginase therapy. Acta Haematol. 1983;69:188-191.
    • (1983) Acta Haematol , vol.69 , pp. 188-191
    • Barbui, T.1    Rodeghiero, F.2    Meli, S.3    Dini, E.4
  • 66
    • 30644472060 scopus 로고    scopus 로고
    • The risk of thrombosis in patients with acute leukemia: Occurrence of thrombosis at diagnosis and during treatment
    • De Stefano V, Sora F, Rossi E, et al. The risk of thrombosis in patients with acute leukemia: occurrence of thrombosis at diagnosis and during treatment. J Thromb Haemost. 2005;3:1985-1992.
    • (2005) J Thromb Haemost , vol.3 , pp. 1985-1992
    • De Stefano, V.1    Sora, F.2    Rossi, E.3
  • 67
    • 0025851862 scopus 로고
    • Long-term results of the HEAVD protocol for adult acute lymphoblastic leukaemia
    • Bassan R, Battista R, D'Emilio A, et al. Long-term results of the HEAVD protocol for adult acute lymphoblastic leukaemia. Eur J Cancer. 1991;27:441-447.
    • (1991) Eur J Cancer , vol.27 , pp. 441-447
    • Bassan, R.1    Battista, R.2    D'Emilio, A.3
  • 68
    • 0027696712 scopus 로고
    • Erwinia- and E. coli-derived L-asparaginase have similar effects on hemostasis: Pilot study in 10 patients with acute lymphoblastic leukemia
    • Castaman G, Rodeghiero F. Erwinia- and E. coli-derived L-asparaginase have similar effects on hemostasis: pilot study in 10 patients with acute lymphoblastic leukemia. Haematologica. 1993;78:57-60.
    • (1993) Haematologica , vol.78 , pp. 57-60
    • Castaman, G.1    Rodeghiero, F.2
  • 69
    • 0029049651 scopus 로고
    • L-asparaginase in acute lymphoblastic leukemia treatment: The role of human antithrombin III concentrates in regulating the prothrombotic state induced by therapy
    • Pogliani EM, Parma M, Baragetti I, et al. L-asparaginase in acute lymphoblastic leukemia treatment: the role of human antithrombin III concentrates in regulating the prothrombotic state induced by therapy. Acta Haematol. 1995;93:5-8.
    • (1995) Acta Haematol , vol.93 , pp. 5-8
    • Pogliani, E.M.1    Parma, M.2    Baragetti, I.3
  • 70
    • 0037439493 scopus 로고    scopus 로고
    • Prophylactic Antithrombin Replacement in Kids with Acute Lymphoblastic Leukemia Treated with Asparaginase Group (PARKAA): A prospective cohort study determining the prevalence of thrombotic events in children with acute lymphoblastic leukemia and a central venous line who are treated with L-Asparaginase
    • Results of the Prophylactic Antithrombin Replacement in Kids with Acute Lymphoblastic Leukemia Treated with Asparaginase (PARKAA) Study
    • Mitchell LG, Andrew M, Hanna K, et al. Prophylactic Antithrombin Replacement in Kids with Acute Lymphoblastic Leukemia Treated with Asparaginase Group (PARKAA): a prospective cohort study determining the prevalence of thrombotic events in children with acute lymphoblastic leukemia and a central venous line who are treated with L-Asparaginase: results of the Prophylactic Antithrombin Replacement in Kids with Acute Lymphoblastic Leukemia Treated with Asparaginase (PARKAA) Study. Cancer. 2003;97:508-516.
    • (2003) Cancer , vol.97 , pp. 508-516
    • Mitchell, L.G.1    Andrew, M.2    Hanna, K.3
  • 71
    • 0033395147 scopus 로고    scopus 로고
    • Clinical relevance of genetic risk factors for thrombosis in paediatric oncology patients with central venous catheters
    • Wermes C, von Depka Prondzinski M, Lichtinghagen R, Barthels M, Welte K, Sykora KW. Clinical relevance of genetic risk factors for thrombosis in paediatric oncology patients with central venous catheters. Eur J Pediatr. 1999;158:S143-S146.
    • (1999) Eur J Pediatr , vol.158
    • Wermes, C.1    Von Depka Prondzinski, M.2    Lichtinghagen, R.3    Barthels, M.4    Welte, K.5    Sykora, K.W.6
  • 72
    • 0028069252 scopus 로고
    • Increased endogenous thrombin generation in children with acute lymphoblastic leukemia: Risk of thrombotic complications in L-Asparaginase- induced antithrombin III deficiency
    • Mitchell L, Hoogendoom H, Giles AR, Vegh P, Andrew M. Increased endogenous thrombin generation in children with acute lymphoblastic leukemia: risk of thrombotic complications in L-Asparaginase-induced antithrombin III deficiency. Blood. 1994;83:386-391.
    • (1994) Blood , vol.83 , pp. 386-391
    • Mitchell, L.1    Hoogendoom, H.2    Giles, A.R.3    Vegh, P.4    Andrew, M.5
  • 73
    • 0038107371 scopus 로고    scopus 로고
    • Thromboembolic events in children with acute lymphoblastic leukemia (BFM protocols): Prednisone verss dexamethasone administration
    • Nowak-Gottl U, Ahike E, Fleischhack G, et al. Thromboembolic events in children with acute lymphoblastic leukemia (BFM protocols): prednisone verss dexamethasone administration. Blood. 2003;101:2529-2533.
    • (2003) Blood , vol.101 , pp. 2529-2533
    • Nowak-Gottl, U.1    Ahike, E.2    Fleischhack, G.3
  • 74
    • 0033652859 scopus 로고    scopus 로고
    • Thrombin generation in children with acute lymphoblastic leukemia: Effect of leukemia immunophenotype subgroups
    • Giordano P, Del Vecchio GC, Santoro N, et al. Thrombin generation in children with acute lymphoblastic leukemia: effect of leukemia immunophenotype subgroups. Ped Hematol Oncol. 2000;17:667-672.
    • (2000) Ped Hematol Oncol , vol.17 , pp. 667-672
    • Giordano, P.1    Del Vecchio, G.C.2    Santoro, N.3
  • 75
    • 0034909125 scopus 로고    scopus 로고
    • Prophylactic therapy with enoxaparin during L-asparaginase treatment in children with acute lymphoblastic leukemia
    • Elhasid R, Lanir N, Sharon R, et al. Prophylactic therapy with enoxaparin during L-asparaginase treatment in children with acute lymphoblastic leukemia. Blood Coagul Fibrin. 2001;12:367-370.
    • (2001) Blood Coagul Fibrin , vol.12 , pp. 367-370
    • Elhasid, R.1    Lanir, N.2    Sharon, R.3
  • 76
    • 0035424112 scopus 로고    scopus 로고
    • Thrombotic events revisited in children with acute lymphoblastic leukemia: Impact of concomitant Escherichia coli asparaginase/prednisone administration
    • Nowak-Gottl U, Heinecke A, von Kries R, Nurnberger W, Munchow N, Junker R. Thrombotic events revisited in children with acute lymphoblastic leukemia: impact of concomitant Escherichia coli asparaginase/prednisone administration. Thromb Res. 2001;103:165-172.
    • (2001) Thromb Res , vol.103 , pp. 165-172
    • Nowak-Gottl, U.1    Heinecke, A.2    Von Kries, R.3    Nurnberger, W.4    Munchow, N.5    Junker, R.6
  • 77
    • 0029559237 scopus 로고
    • Resistance to activated protein C (APCR) in children with acute lymphoblastic leukaemia: The need for a prospective multicentre study
    • Nowak-Gottl U, Aschka I, Koch HG, et al. Resistance to activated protein C (APCR) in children with acute lymphoblastic leukaemia: the need for a prospective multicentre study. Blood Coagul Fibrinolysis. 1995;6:761-764.
    • (1995) Blood Coagul Fibrinolysis , vol.6 , pp. 761-764
    • Nowak-Gottl, U.1    Aschka, I.2    Koch, H.G.3
  • 79
    • 0021932510 scopus 로고
    • Altered von Willebrand factor molecule in children with thrombosis following asparaginase-prednisone-vincristine therapy for leukemia
    • Pui CH, Chesney CM, Weed J, Jackson CW. Altered von Willebrand factor molecule in children with thrombosis following asparaginase-prednisone- vincristine therapy for leukemia. J Clin Oncol. 1985;3:1266-1272.
    • (1985) J Clin Oncol , vol.3 , pp. 1266-1272
    • Pui, C.H.1    Chesney, C.M.2    Weed, J.3    Jackson, C.W.4
  • 80
    • 0025003474 scopus 로고
    • The coagulopathy of childhood leukemia: Thrombin activation or primary fibrinolysis?
    • Abshire TC, Gold SH, Odom LF, Carson SD, Hathaway WE. The coagulopathy of childhood leukemia: thrombin activation or primary fibrinolysis? Cancer. 1990;66:716-721.
    • (1990) Cancer , vol.66 , pp. 716-721
    • Abshire, T.C.1    Gold, S.H.2    Odom, L.F.3    Carson, S.D.4    Hathaway, W.E.5
  • 81
    • 0022443776 scopus 로고
    • Four-agent induction and intensive asparaginase therapy for treatment of childhood acute lymphoblastic leukemia
    • Clavell LA, Gelber RD, Cohen HJ, et al. Four-agent induction and intensive asparaginase therapy for treatment of childhood acute lymphoblastic leukemia. N Engl J Med. 1986;315:657-663.
    • (1986) N Engl J Med , vol.315 , pp. 657-663
    • Clavell, L.A.1    Gelber, R.D.2    Cohen, H.J.3
  • 82
    • 0029797696 scopus 로고    scopus 로고
    • Changes in coagulation and fibrinolysis in childhood ALL: A two-step dose reduction of one E. coli asparaginase preparation
    • Nowak-Gottl U, Ahlke E, Schulze-Westhoff P, Boos J. Changes in coagulation and fibrinolysis in childhood ALL: a two-step dose reduction of one E. coli asparaginase preparation. Br J Haematol. 1996;95:123-126.
    • (1996) Br J Haematol , vol.95 , pp. 123-126
    • Nowak-Gottl, U.1    Ahlke, E.2    Schulze-Westhoff, P.3    Boos, J.4
  • 83
    • 0030326241 scopus 로고    scopus 로고
    • Influence of two different Escherichia coli asparaginase preparations on fibrinolytic proteins in childhood ALL
    • Nowak-Gottl U, Werber G, Ziemann D, Ahlke E, Boos J. Influence of two different Escherichia coli asparaginase preparations on fibrinolytic proteins in childhood ALL. Haematologica. 1996;81:127-131.
    • (1996) Haematologica , vol.81 , pp. 127-131
    • Nowak-Gottl, U.1    Werber, G.2    Ziemann, D.3    Ahlke, E.4    Boos, J.5
  • 84
    • 0022590309 scopus 로고
    • Hemostatic changes in children with acute lymphoblastic leukemia treated according to two different Lasparaginase schedules
    • Miniero R, Pastore G, Saracco P, et al. Hemostatic changes in children with acute lymphoblastic leukemia treated according to two different Lasparaginase schedules. Am J Pediatr Hematol Oncol. 1986;8:116-120.
    • (1986) Am J Pediatr Hematol Oncol , vol.8 , pp. 116-120
    • Miniero, R.1    Pastore, G.2    Saracco, P.3
  • 85
    • 0030832963 scopus 로고    scopus 로고
    • Changes in coagulation and fibrinolysis in childhood acute lymphoblastic leukaemia re-induction therapy using three different asparaginase preparations
    • Nowak-Gottl U, Ahlke E, Klosel K, Jurgens H, Boos J. Changes in coagulation and fibrinolysis in childhood acute lymphoblastic leukaemia re-induction therapy using three different asparaginase preparations. Eur J Pediatr. 1997;156:848-850.
    • (1997) Eur J Pediatr , vol.156 , pp. 848-850
    • Nowak-Gottl, U.1    Ahlke, E.2    Klosel, K.3    Jurgens, H.4    Boos, J.5
  • 86
    • 0027978784 scopus 로고
    • Minimal effects of E. coli and Erwinia asparaginase on the coagulation system in childhood acute lymphoblastic leukemia: A randomized study
    • Risseeuw-Appel IM, Dekker I, Hop WC, Hahlen K. Minimal effects of E. coli and Erwinia asparaginase on the coagulation system in childhood acute lymphoblastic leukemia: a randomized study. Med Pediatr Oncol. 1994;23:335-343.
    • (1994) Med Pediatr Oncol , vol.23 , pp. 335-343
    • Risseeuw-Appel, I.M.1    Dekker, I.2    Hop, W.C.3    Hahlen, K.4
  • 87
    • 0022883955 scopus 로고
    • Correction of hemostatic imbalances induced by L-asparaginase therapy in children with acute lymphoblastic leukemia
    • Zaunschirm A, Muntean W. Correction of hemostatic imbalances induced by L-asparaginase therapy in children with acute lymphoblastic leukemia. Pediatr Hematol Oncol. 1986;3:19-25.
    • (1986) Pediatr Hematol Oncol , vol.3 , pp. 19-25
    • Zaunschirm, A.1    Muntean, W.2
  • 88
    • 0022547976 scopus 로고
    • Effect of L-asparaginase therapy for acute lymphoblastic leukemia on plasma vitamin K-dependent coagulation factors and inhibitors
    • Bezeaud A, Drouet L, Leverger G, Griffin JH, Guillin MC. Effect of L-asparaginase therapy for acute lymphoblastic leukemia on plasma vitamin K-dependent coagulation factors and inhibitors. J Pediatr. 1986;108:698-701.
    • (1986) J Pediatr , vol.108 , pp. 698-701
    • Bezeaud, A.1    Drouet, L.2    Leverger, G.3    Griffin, J.H.4    Guillin, M.C.5
  • 89
    • 0020031961 scopus 로고
    • The effect of L-asparaginase on antithrombin, plasminogen, and plasma coagulation during therapy for acute lymphoblastic leukemia
    • Priest JR, Ramsay NK, Bennett AJ, Krivit W, Edson JR. The effect of L-asparaginase on antithrombin, plasminogen, and plasma coagulation during therapy for acute lymphoblastic leukemia. J Pediatr. 1982;100:990-995.
    • (1982) J Pediatr , vol.100 , pp. 990-995
    • Priest, J.R.1    Ramsay, N.K.2    Bennett, A.J.3    Krivit, W.4    Edson, J.R.5
  • 90
    • 0029962921 scopus 로고    scopus 로고
    • Inhibition of hypercoagulation by antithrombin substitution in E. coli L-asparaginase-treated children
    • Nowak-Gottl U, Kuhn N, Wolff JE, et al. Inhibition of hypercoagulation by antithrombin substitution in E. coli L-asparaginase-treated children. Eur J Haematol. 1996;56:35-38.
    • (1996) Eur J Haematol , vol.56 , pp. 35-38
    • Nowak-Gottl, U.1    Kuhn, N.2    Wolff, J.E.3
  • 91
    • 0025076181 scopus 로고
    • Unbalanced coagulation-fibrinolysis potential during L-asparaginase therapy in children with acute lymphoblastic leukaemia
    • Semeraro N, Montemurro P, Giordano P, et al. Unbalanced coagulation-fibrinolysis potential during L-asparaginase therapy in children with acute lymphoblastic leukaemia. Thromb Haemost. 1990;64:38-40.
    • (1990) Thromb Haemost , vol.64 , pp. 38-40
    • Semeraro, N.1    Montemurro, P.2    Giordano, P.3
  • 92
    • 0023683703 scopus 로고
    • Intravascular coagulation phenomena associated with prevalent fall in fibrinogen and plasminogen during L-asparaginase treatment in leukemic children
    • Legnani C, Palareti G, Pession A, et al. Intravascular coagulation phenomena associated with prevalent fall in fibrinogen and plasminogen during L-asparaginase treatment in leukemic children. Haemostasis. 1988;18:179-186.
    • (1988) Haemostasis , vol.18 , pp. 179-186
    • Legnani, C.1    Palareti, G.2    Pession, A.3
  • 93
    • 0023782228 scopus 로고
    • Increased antithrombin III concentration in children with acute lymphatic leukaemia receiving L-asparaginase therapy
    • O'Meara A, Daly M, Hallinan FH. Increased antithrombin III concentration in children with acute lymphatic leukaemia receiving L-asparaginase therapy. Med Pediatr Oncol. 1988;16:169-174.
    • (1988) Med Pediatr Oncol , vol.16 , pp. 169-174
    • O'Meara, A.1    Daly, M.2    Hallinan, F.H.3
  • 94
    • 0023219058 scopus 로고
    • Effect of L-asparaginase administration on coagulation and platelet function in children with leukemia
    • Homans AC, Rybak ME, Baglini RL, Tiarks C, Steiner ME, Forman EN. Effect of L-asparaginase administration on coagulation and platelet function in children with leukemia. J Clin Oncol. 1987;5:811-817.
    • (1987) J Clin Oncol , vol.5 , pp. 811-817
    • Homans, A.C.1    Rybak, M.E.2    Baglini, R.L.3    Tiarks, C.4    Steiner, M.E.5    Forman, E.N.6
  • 95
    • 0035079642 scopus 로고    scopus 로고
    • Effects of high-dose methotrexate on the hemostatic system in childhood acute lymphoblastic leukemia
    • Totan M, Dagdemir A, Ak AR, Albayrak D, Kucukoduk S. Effects of high-dose methotrexate on the hemostatic system in childhood acute lymphoblastic leukemia. Med Pediatr Oncol. 2001;36:429-433.
    • (2001) Med Pediatr Oncol , vol.36 , pp. 429-433
    • Totan, M.1    Dagdemir, A.2    Ak, A.R.3    Albayrak, D.4    Kucukoduk, S.5
  • 96
    • 0346248551 scopus 로고    scopus 로고
    • Thromboembolism in children with acute lymphoblastic leukemia treated on Dana Farber Cancer Institute Protocols: Effect of age and risk stratification of ALL
    • Athale U, Mah D, Davidson A, Nagel K, Odame I, Chan AKC. Thromboembolism in children with acute lymphoblastic leukemia treated on Dana Farber Cancer Institute Protocols: effect of age and risk stratification of ALL. Med Ped Oncol. 2003;41:310.
    • (2003) Med Ped Oncol , vol.41 , pp. 310
    • Athale, U.1    Mah, D.2    Davidson, A.3    Nagel, K.4    Odame, I.5    Chan, A.K.C.6
  • 97
    • 21344437094 scopus 로고    scopus 로고
    • Thrombotic complications in children treated for ALL: A single centre experience
    • Mathew LG, Ortin M, Pinkerton CR. Thrombotic complications in children treated for ALL: a single centre experience. Med Ped Oncol. 2003;41:310.
    • (2003) Med Ped Oncol , vol.41 , pp. 310
    • Mathew, L.G.1    Ortin, M.2    Pinkerton, C.R.3
  • 98
    • 0141478862 scopus 로고    scopus 로고
    • T-immunophenotype is associated with an increased prevalence of thrombosis in children with acute lymphoblastic leukemia: A retrospective study
    • Giordano P, Santoro N, Del Vecchio GC, Rizzari C, Masera G, De Mattia D. T-immunophenotype is associated with an increased prevalence of thrombosis in children with acute lymphoblastic leukemia: a retrospective study. Haematologica. 2003;88:1079-1080.
    • (2003) Haematologica , vol.88 , pp. 1079-1080
    • Giordano, P.1    Santoro, N.2    Del Vecchio, G.C.3    Rizzari, C.4    Masera, G.5    De Mattia, D.6
  • 99
    • 0036311693 scopus 로고    scopus 로고
    • Low plasma levels of hemostatic proteins during the induction phase in children with acute lymphoblastic leukemia: A retrospective study by the JACLS
    • Hongo T, Okada S, Ohzeki T, et al. Low plasma levels of hemostatic proteins during the induction phase in children with acute lymphoblastic leukemia: a retrospective study by the JACLS. Pediatrics Intern. 2002;44:293-299.
    • (2002) Pediatrics Intern , vol.44 , pp. 293-299
    • Hongo, T.1    Okada, S.2    Ohzeki, T.3
  • 101
    • 0032859845 scopus 로고    scopus 로고
    • Bleeding and thrombosis in children with acute lymphoblastic leukaemia, treated according to the ALL-BFM-90 protocol
    • Sutor AH, Mall V, Thomas KB. Bleeding and thrombosis in children with acute lymphoblastic leukaemia, treated according to the ALL-BFM-90 protocol. Klin Padiatr. 1999;211:201-204.
    • (1999) Klin Padiatr , vol.211 , pp. 201-204
    • Sutor, A.H.1    Mall, V.2    Thomas, K.B.3
  • 102
    • 0020066012 scopus 로고
    • A syndrome of thrombosis and hemorrhage complicating L-asparaginase therapy for childhood acute lymphoblastic leukemia
    • Priest JR, Ramsay NK, Steinherz PG, et al. A syndrome of thrombosis and hemorrhage complicating L-asparaginase therapy for childhood acute lymphoblastic leukemia. J Pediatr. 1982;100:984-989.
    • (1982) J Pediatr , vol.100 , pp. 984-989
    • Priest, J.R.1    Ramsay, N.K.2    Steinherz, P.G.3
  • 103
    • 0030023875 scopus 로고    scopus 로고
    • Exact estimates for a rate ratio
    • Martin DO, Austin H. Exact estimates for a rate ratio. Epidemiology. 1996;7:29-33.
    • (1996) Epidemiology , vol.7 , pp. 29-33
    • Martin, D.O.1    Austin, H.2
  • 104
    • 0025062987 scopus 로고
    • Cancer procoagulant in acute lymphoblastic leukemia
    • Alessio MG, Falanga A, Consonni R, et al. Cancer procoagulant in acute lymphoblastic leukemia. Eur J Haematol. 1990;45:78-81.
    • (1990) Eur J Haematol , vol.45 , pp. 78-81
    • Alessio, M.G.1    Falanga, A.2    Consonni, R.3
  • 105
    • 33749350909 scopus 로고    scopus 로고
    • Pathogenesis of thrombosis in cancer
    • Donati MB, Falanga A. Pathogenesis of thrombosis in cancer. Hematol J. 2003;4:63-67.
    • (2003) Hematol J , vol.4 , pp. 63-67
    • Donati, M.B.1    Falanga, A.2
  • 106
    • 0031054398 scopus 로고    scopus 로고
    • Incidence of objectively diagnosed thromboembolic disease in cancer patients undergoing cytotoxic chemotherapy and/or hormonal therapy
    • Shlebak AA, Smith DB. Incidence of objectively diagnosed thromboembolic disease in cancer patients undergoing cytotoxic chemotherapy and/or hormonal therapy. Cancer Chemother Pharmacol. 1997;39:462-466.
    • (1997) Cancer Chemother Pharmacol , vol.39 , pp. 462-466
    • Shlebak, A.A.1    Smith, D.B.2
  • 107
    • 0942265619 scopus 로고    scopus 로고
    • Symptomatic venous thromboembolism in cancer patients treated with chemotherapy: An underestimated phenomenon
    • Otten HM, Mathijssen J, ten Cate H, et al. Symptomatic venous thromboembolism in cancer patients treated with chemotherapy: an underestimated phenomenon. Arch Intern Med. 2004;164:190-194.
    • (2004) Arch Intern Med , vol.164 , pp. 190-194
    • Otten, H.M.1    Mathijssen, J.2    Ten Cate, H.3
  • 108
    • 13444256137 scopus 로고    scopus 로고
    • Malignancies, prothrombotic mutations, and the risk of venous thrombosis
    • Blom JW, Doggen CJ, Osanto S, Rosendaal FR. Malignancies, prothrombotic mutations, and the risk of venous thrombosis. JAMA. 2005;293:715-722.
    • (2005) JAMA , vol.293 , pp. 715-722
    • Blom, J.W.1    Doggen, C.J.2    Osanto, S.3    Rosendaal, F.R.4
  • 109
    • 0028008663 scopus 로고
    • Venous thromboembolic complications (VTE) in children: First analyses of the Canadian Registry of VTE
    • Andrew M, David M, Adams M, et al. Venous thromboembolic complications (VTE) in children: first analyses of the Canadian Registry of VTE. Blood. 1994;83:1251-1257.
    • (1994) Blood , vol.83 , pp. 1251-1257
    • Andrew, M.1    David, M.2    Adams, M.3
  • 111
  • 112
    • 17844369421 scopus 로고    scopus 로고
    • Thrombosis of the cerebral veins and sinuses
    • Jan Stam MD. Thrombosis of the cerebral veins and sinuses. New Engl J Med. 2005;352:1791-1798.
    • (2005) New Engl J Med , vol.352 , pp. 1791-1798
    • Jan Stam, M.D.1
  • 114
    • 4544373299 scopus 로고    scopus 로고
    • Consultations on patients with venous or arterial diseases
    • (Am Soc Hematol Educ Program)
    • Alving BM, Francis CW, Hiatt WR, Jackson MR. Consultations on patients with venous or arterial diseases. Hematology (Am Soc Hematol Educ Program). 2003:540-558.
    • (2003) Hematology , pp. 540-558
    • Alving, B.M.1    Francis, C.W.2    Hiatt, W.R.3    Jackson, M.R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.