The effect of endogenous nitric oxide on mechanical ciliostimulation of human nasal mucosa

Clinical and Experimental Allergy

Volumn 36, Issue 10, 2006, Pages 1254-1259

  Alberty, J ^a,b   Stoll, W ^a   Rudack, C ^a  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b Department of Otorhinolaryngology ^*  (Germany)

Author keywords

Allergic rhinitis; Mechanical ciliostimulation; Mucociliary transport; Nitric oxide

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; TUMOR NECROSIS FACTOR ALPHA;

ALLERGIC RHINITIS; ARTICLE; CILIARY MOTILITY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; EXPLANT; FLUORESCENCE; HUMAN; HUMAN CELL; IN VITRO STUDY; INCUBATION TIME; LASER MICROSCOPY; MECHANICAL STIMULATION; NOSE MUCOSA; PRIORITY JOURNAL;

CILIA; ESCHERICHIA COLI; HUMANS; LIPOPOLYSACCHARIDES; MICROSCOPY, CONFOCAL; MUCOCILIARY CLEARANCE; NASAL MUCOSA; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; RHINITIS, ALLERGIC, SEASONAL; STRESS, MECHANICAL; TISSUE CULTURE TECHNIQUES; UP-REGULATION;

EID: 33749317173     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/j.1365-2222.2006.02563.x     Document Type: Article

References (31)

1. Boek WM, Graamans K, Natzijl H, van Rijk PP, Huizing EH. Nasal mucociliary transport: new evidence for a key role of ciliary beat frequency. Laryngoscope 2002; 112:570-3.
2. Houtmeyers E, Gosselink R, Gayan-Ramirez G, Decramer M. Regulation of mucociliary clearance in health and disease. Eur Respir J 1999; 13:1177-88.
3. Jain B, Rubinstein I, Robbins RA, Sisson JH. TNF-alpha and IL-1 beta upregulate nitric oxide-dependent ciliary motility in bovine airway epithelium. Am J Physiol 1995; 268:L911-7.
4. Kim JW, Min YG, Rhee CS et al. Regulation of mucociliary motility by nitric oxide and expression of nitric oxide synthase in the human sinus epithelial cells. Laryngoscope 2001; 111:246-50.
5. Furukawa K, Harrison DG, Saleh D, Shennib H, Chagnon FP, Giaid A. Expression of nitric oxide synthase in the human nasal mucosa. Am J Respir Crit Care Med 1996; 153:847-50.
6. Hess A, Bloch W, Rocker J, Addicks K, Stennert E, Michel O. In vitro expression of inducible nitric oxide synthase in the nasal mucosa of guinea pigs after incubation with lipopolysaccharides or cytokines. Eur Arch Otorhinolaryngol 1998; 255:448-53.
7. Kharitonov SA, Rajakulasingam K, O'Connor B, Durham SR, Barnes PJ. Nasal nitric oxide is increased in patients with asthma and allergic rhinitis and may be modulated by nasal glucocorticoids. J Allergy Clin Immunol 1997; 99:58-64.
8. Sato M, Fukuyama N, Sakai M, Nakazawa H. Increased nitric oxide in nasal lavage fluid and nitrotyrosine formation in nasal mucosa - indices for severe perennial nasal allergy. Clin Exp Allergy 1998; 28:597-605.
9. Alberty J, August C, Stoll W, Rudack C. The effect of endogenous nitric oxide on cholinergic ciliary stimulation of human nasal mucosa. Laryngoscope 2004; 114:1642-7.
10. Di Benedetto G, Lopez-Vidriero MT, Clarke SW. The effect of perfusion flow-rate on ciliary activity in vitro. Clin Respir Physiol 1987; 23 (Suppl. 12):364s.
11. Wong LB, Miller IF, Yeates DB. Regulation of ciliary beat frequency by autonomic mechanisms: in vitro. J Appl Physiol 1988; 65:1895-901.
12. 2+ signaling in intact tracheal epithelium maintained under normal gravity and simulated microgravity. Am J Respir Cell Mol Biol 1998; 18:602-10.
13. Homolya L, Steinberg TH, Boucher RC. Cell to cell communication in response to mechanical stress via bilateral release of ATP and UTP in polarized epithelia. J Cell Biol 2000; 150:1349-60.
14. Takeno S, Osada R, Furukido K, Chen JH, Yajin K. Increased nitric oxide production in nasal epithelial cells from allergic patients - RT-PCR analysis and direct imaging by a fluorescence indicator: DAF-2 DA. Clin Exp Allergy 2001; 31:881-8.
15. Mwimbi XK, Muimo R, Green M, Mehta A. Protein kinase C regulates the flow rate-dependent decline in human nasal ciliary beat frequency in vitro. J Aerosol Med 2000; 13:273-80.
16. Sanderson MJ, Dirksen ER. Mechanosensitivity of cultured ciliated cells from the mammalian respiratory tract: implications for the regulation of mucociliary transport. Proc Natl Acad Sci USA 1986; 83:7302-6.
17. Barr GS, Tewary AK. Alteration of airflow and mucociliary transport in normal subjects. J Laryngol Otol 1993; 107:603-4.
18. Simmen D, Scherrer JL, Moe K, Heinz B. A dynamic and direct visualization model for the study of nasal airflow. Arch Otolaryngol Head Neck Surg 1999; 125:1015-21.
19. Boitano S, Dirksen ER, Sanderson MJ. Intercellular propagation of calcium waves mediated by inositol trisphosphate. Science 1992; 258:292-5.
20. Felix JA, Woodruff ML, Dirksen ER. Stretch increases inositol 1,4,5-trisphosphate concentration in airway epithelial cells. Am J Respir Cell Mol Biol 1996; 14:296-301.
21. Yang B, Schlosser RJ, McCaffrey TV. Dual signal transduction mechanisms modulate ciliary beat frequency in upper airway epithelium. Am J Physiol 1996; 270:L745-51.
22. Chen JH, Takeno S, Osada R, Ueda T, Yajin K. Modulation of ciliary activity by tumor necrosis factor-alpha in cultured sinus epithelial cells. Possible roles of nitric oxide. Hiroshima J Med Sci 2000; 49:49-55.
23. 2+-dependent and -independent manner. Am J Physiol 1998; 275:C790-7.
24. i enhances ciliary activity in rabbit trachea. J Physiol (London) 1999; 516:179-90.
25. Zagoory O, Braiman A, Priel Z. The mechanism of ciliary stimulation by acetylcholine: roles of calcium, PKA, and PKG. J Gen Physiol 2002; 119:329-39.
26. 2+ action on ciliary beat frequency in single ovine airway epithelial cells. J Physiol (London) 1999; 520 (Part 3):851-65.
27. Salathe M, Lieb T, Bookman RJ. Lack of nitric oxide involvement in cholinergic modulation of ovine ciliary beat frequency. J Aerosol Med 2000; 13:219-30.
28. Zhang L, Sanderson MJ. The role of cGMP in the regulation of rabbit airway ciliary beat frequency. J Physiol 2003; 551:765-76.
29. Ma W, Silberberg SD, Priel Z. Distinct axonemal processes underlie spontaneous and stimulated airway ciliary activity. J Gen Physiol 2002; 120:875-85.
30. Motta G, Passali D, De VI et al. A multicenter trial of specific local nasal immunotherapy. Laryngoscope 2000; 110:132-9.
31. Sun SS, Hsieh JF, Tsai SC, Ho YJ, Kao CH. Evaluation of nasal mucociliary clearance function in allergic rhinitis patients with technetium 99m-labeled macroaggregated albumin rhinoscintigraphy. Ann Otol Rhinol Laryngol 2002; 111:77-9.