Topography of ampiiiregulin expression in cultured human keratinocytes: Colocalization with the epidermal growth factor receptor and CD44

In Vitro Cellular and Developmental Biology - Animal

Volumn 34, Issue 2, 1998, Pages 183-189

  Nylander, Nicola ^a   Smith, Lynne T ^a   Underwood, Robert A ^a   Piepkorn, Michael ^a  

^a UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

Amphiregulin; CD44; Epidermal growth factor receptor; Heparin binding epidermal growth factor; Proteoglycan

Indexed keywords

AMPHIREGULIN; EPIDERMAL GROWTH FACTOR RECEPTOR; HERMES ANTIGEN; PLEIOTROPHIN;

ANTIBODY LABELING; ARTICLE; CELL GROWTH; CELLULAR DISTRIBUTION; GROWTH REGULATION; HUMAN; HUMAN CELL; KERATINOCYTE; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RECEPTOR BINDING; SKIN CELL;

EID: 33749286075     PISSN: 10712690     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Ahmed, L; Piepkom, M. The antiproliferalive effects of enzymatic deglycosylation and metabolic undersulfation of proteoglycans from the cell surface. J. Invest. Dermatol. 97:43-49; 1991.
2. Amalric, F.; Bouche, G.; Bonnet, H., et al. Fibroblast growth factor-2 (FGF2) in the nucleus: translocation process and targets. Biochem. Pharmacol. 47:111-115; 1994.
3. Bennett, K. L; Jackson, D. G.; Simon, J. C., et al. CD44 isoforms containing exon V3 are responsible for the presentation of heparin-binding growth factor. J. Cell Biol. 128:687-698; 1995.
4. Cook, P. W.; Mattox, P. A.; Keeble, W. W., et al. A heparin sulfate-regulated human keratinocyte autocrine factor is similar or identical to amphiregulin. Mol. Cell. Biol. 11:2547-2557; 1991.
5. Cook, P. W.; Mattox, P. A.; Keeble, W. W., et al. Inhibition of autonomous human keratinocyle proliferation and amphiregulin mitogenic activity by sulfated polysaccharides. In Vitro Cell. Dev. Biol. 28A:218-222; 1992a.
6. Cook, P. W.; Pittelkow, M. R.; Keeble, W. W., et al. Amphiregulin messenger RNA is elevated in psoriatic epidermis and gastrointestinal carcinomas. Cancer Res. 52:3224-3227; 1992b.
7. Ebert, M.; Yokoyama, M.; Kobrin, M. S., et al. Induction and expression of amphiregulin in human pancreatic cancer. Cancer Res. 54:3959-3962; 1994.
8. Elder, J, T.; Xia, L.-Q.; Majmudar, G., et al. Selective overexpression of amphiregulin in cutaneous squamous and basal cell carcinoma. J. Invest. Dermatol. 100:492; 1993.
9. Hardas, B.; Yang, Q.; Elder, J. T. Regulation of amphiregulin, a heparinbinding, EGF-like growth factor, in human skin. J. Invest. Dermatol. 98:575; 1992.
10. Hashimoto, K.; Higashiyama, S.; Asada, H., et al. Heparin-binding epidermal growth factor-like growth factor is an autocrine growth factor for human keratinocytes. J. Biol. Chem. 269:20060-20066; 1994.
11. Hawker, J. R., Jr.; Granger, H. J. Nuclear accumulation of exogenous basic fibroblast growth factor in endothelial, fibroblast, and myoblast cell lines results in diverse biological responses. In Vitro Cell. Dev. Biol. 30A:653-663; 1994.
12. Jackson, D. G.; Buckley, J.; Bell, J. I. Multiple variants of the human lymphocyte homing receptor CD44 generated by insertions at a single site in the extracellular domain. J. Biol. Chem. 267:4732-4739; 1992.
13. Johnson, G. R.; Kannan, B.; Shoyab, M., et al. Amphiregulin induces tyrosine phosphorylation of the epidermal growth factor receptor and p!85erbB2. Evidence that amphiregulin acts exclusively through the epidermal growth factor receptor at the surface of human epithelial cells. J. Biol. Chem. 268:2924-2931; 1993.
14. Johnson, G. R.; Saeki, T.; Auersperg, N., et al. Response to and expression of amphiregulin by ovarian carcinoma and normal ovarian surface epithelial cells: nuclear localization of endogenous amphiregulin. Biochem. Biophys. Res. Commun. 180:481-488; 1991.
15. Johnson, G. R.; Saeki, T.; Gordon, A. W., et al. Autocrine action of amphiregulin in a colon carcinoma cell line and immunocytochemical localization of amphiregulin in human colon. J. Cell Biol. 118:741751; 1992.
16. Johnson, G. R.; Wbng, L. Heparan sulfate is essential to amphiregulin-induced mitogenic signaling by the epidermal growth factor receptor. J. Biol. Chem. 43:27149-27151; 1994.
17. Kugelman, L. C.; Ganguly, S.; Haggerty, J. G., et al. The core protein of epican, a heparan sulfate proteoglycan on keratinocytes, is an alternative form of CD44. J. Invest. Dermatol. 99:381-385; 1992.
18. Li, S.; Plowman, G. D.; Buckley, S. D., et al. Heparin inhibition of autonomous growth implicates amphiregulin as an autocrine growth factor for normal human mammary epithelial cells. J. Cell. Physiol. 153:103-111; 1992.
19. Modrell, B.; McDonald, V. L.; Shoyab, M. The interaction of amphiregulin with nuclei and putative nuclear localization sequence binding proteins. Growth Factors 7:305-314; 1992.
20. Nakamura, K.; Iwamoto, R.; Mekada, E. Membrane-anchored heparin-binding EGF-like growth factor (HB-EGF) and diphtheria toxin receptorassociated protein (DRAP27)/CD9 form a complex with integrin α3β1 at cell-cell contact sites. J. Cell Biol. 129:1691-1705; 1995.
21. Nanney, L. B.; Slosckeck, C. M.; King, L. E., et al. Immunolocalization of epidermal growth factor receptors in normal developing human skin. J. Invest. Dermatol. 94:742-748; 1990.
22. Normanno, N.; Qi, C.-F.; Gullick, W. J., et al. Expression of amphiregulin, cripto-1, and heregulin alpha in human breast cancer cells. Int. J. Oncol. 2:903-911; 1993.
23. Piepkorn, M. Overexpression of amphiregulin, a major autocrine growth factor for cultured human keratinocytes, in hyperproliferative skin diseases. Am. J. Dermatopathol. 18:165-171; 1996.
24. Piepkorn, M.; Lo, C.; Plowman, G. Amphiregulin-dependent proliferation of cultured human keratinocytes: autocrine growth, the effects of exogenous recombinant cytokine, and apparent requirement for heparinlike glycosaminoglycans. J. Cell. Physiol. 159:114-120; 1994.
25. Piepkorn, M.j Underwood, R. A.; Henneman, C., et al. Expression of amphiregulin is regulated in cultured human keratinocytes and in developing fetal skin. J. Invest. Dermatol. 105:802-809; 1995.
26. Plowman, G. D.; Green, J. M.; McDonald, V. L., et al. The amphiregulin gene encodes a novel epidermal growth factor-related protein with tumorinhibitory activity. Mol. Cell. Biol. 10:1969-1981; 1990.
27. Sakai, Y.; Nelson, K. G.; Snedeker, S., et al. Expression of epidermal growth factor in suprabasal cells of stratified squamous epithelia: implications for a role in differentiation. Cell Growth & Differ. 5:527-535; 1994.
28. Screaton, G. R.; Cell, M. V.; Jackson, D. G., et al. Genomic structure of DNA encoding the lymphocyte homing receptor CD44 reveals at least 12 alternatively spliced exons. Proc. Natl. Acad. Sci. USA 89:1216012164; 1992.
29. Sehgal, I.; Bailey, J.; Hitzemann, K., et al. Epidermal growth factor receptordependent stimulation of amphiregulin expression in androgen-stimulated human prostate cancer cells. Mol. Biol. Cell 5:339-347; 1994.
30. Shoyab, M.; McDonald, V. L; Bradley, J. G., et al. Amphiregulin: a bifunctional growth-modulating glycoprotein produced by the phorbol 12myristate 13-acetate-treated human breast adenocarcinoma cell line MCF-7. Proc. Natl. Acad. Sci. USA 85:6528-6532; 1988.
31. Shoyab, M.; Plowman, G. D.; McDonald, V. L., et al. Structure and function of human amphiregulin: a member of the epidermal growth factor family. Science 243:1074-1076; 1989.